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The Uab Research Foundation
The Uab Research Foundation_20100121
The Uab Research Foundation_20131212
The Uab Research Foundation_20100128

The Uab Research Foundation patents


Recent patent applications related to The Uab Research Foundation. The Uab Research Foundation is listed as an Agent/Assignee. Note: The Uab Research Foundation may have other listings under different names/spellings. We're not affiliated with The Uab Research Foundation, we're just tracking patents.

ARCHIVE: New 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 | Company Directory "T" | The Uab Research Foundation-related inventors


Multitargeting onocolytic adenovirus, methods of use, and methods of making

To increase the therapeutic potential of these oncolytic viruses based on a 24 base pair deletion in the viral E1 A gene (D24), a conditionally replicating adenovirus targeting multiple receptors upregulated on tumors was generated by incorporating an Ad5/3 fiber with a carboxyl terminus RGD ligand. The virus displayed full... The Uab Research Foundation

Diagnosing and treating iga nephropathy

Provided are methods of diagnosing IgA nephropathy in a subject. Optionally, the methods comprise isolating an IgG from the subject and determining whether the IgG binds to a galactose-deficient IgA1. Optionally, the methods comprise providing a biological sample from the subject and detecting in the sample a mutation in a... The Uab Research Foundation

Compositions and methods for inhibiting fibrosis

Provided herein are compositions and methods for treating or preventing fibrosis.... The Uab Research Foundation

Use of nitrite salts in chronic ischemia

Methods of treating a subject who has chronic tissue ischemia are disclosed. The methods can include administering to the subject a pharmaceutical composition comprising inorganic nitrite or a pharmaceutically acceptable salt thereof, for a time and in an amount sufficient to result in blood vessel growth in the ischemic tissue.... The Uab Research Foundation

Force profile control for the application of horizontal resistive force

Systems and methods for controlling application of horizontal resistive force to a user walking on a treadmill to provide substantially constant force even if the user changes his or her relative position on the treadmill. The systems and methods can improve the user experience when force is applied while also... The Uab Research Foundation

Protective helmets having energy absorbing tethers

In one embodiment, a tether system for use with a protective helmet worn by a user includes multiple tethers, each tether having a first end adapted to attach to a shell of the protective helmet and a second end adapted to attach to an article worn by the user, wherein... The Uab Research Foundation

Protective helmets having energy absorbing liners

In one embodiment, a protective helmet includes an outer shell and an inner liner provided within the outer shell, the liner comprising an energy absorber including a first layer, an opposed second layer, and a plurality of energy absorbing columns provided between the layers, wherein the columns include relatively long... The Uab Research Foundation

Protective helmets having energy absorbing shells

In one embodiment, a protective helmet includes an outer shell made of a polyethylene material, wherein the shell is locally deformable when impacted with a strong force and an inner liner provided within the outer shell. A protective helmet comprising: an outer shell made of a polyethylene material, wherein the... The Uab Research Foundation

System and performing exercise testing and training

Disclosed are various approaches for determining the maximum oxygen consumption of a person, also known as maximum aerobic capacity or VO2 Max. A person is positioned on a treadmill. Attached to the person is a harness configured to apply a horizontal force to the person. A work rate for the... The Uab Research Foundation

Methods for increasing cftr activity

The present disclosure provides compounds effective in increasing mucociliary clearance in a subject. In one embodiment, the compounds are of the general formula I. The present disclosure further shows that such compounds are effective in increasing activation of the CFTR, thereby increasing mucociliary clearance in the subject. The present disclosure... The Uab Research Foundation

Amyotrophic lateral sclerosis (als) biomarkers and uses thereof

Provided herein are Amyotrophic lateral sclerosis (ALS) biomarkers and methods of using these ALS biomarkers to diagnose and treat ALS.... The Uab Research Foundation

Msp nanopores and related methods

Provided herein are Mycobacterium smegmatis porin nanopores, systems that comprise these nanopores, and methods of using and making these nanopores. Such nanopores may be wild-type MspA porins, mutant MspA porins, wild-type MspA paralog porins, wild-type MspA homolog porins, mutant MspA paralog porins, mutant MspA homolog porins, or single-chain Msp porins.... The Uab Research Foundation

Systems and methods for providing radiotherapy treatment

In one embodiment, radiotherapy treatment is provided to a target volume of a patient by configuring a multileaf collimator of a radiation treatment machine in a first orientation so as to form an actual aperture having a first orientation, delivering radiation to the target volume through the actual aperture while... The Uab Research Foundation

Protective helmets for disaster situations

In one embodiment, a protective helmet for disaster situation includes a rigid outer shell and an electronic system integrated into the helmet that includes an electronic location system configured to transmit electromagnetic signals that can be used to locate the wearer of the helmet.... The Uab Research Foundation

Reclining transport chairs

A transport chair is provided that includes a base frame, a seat assembly pivotally mounted to the base, and a footrest assembly pivotally mounted to the base frame, the footrest assembly being associated with the seat assembly so as to pivot in unison with the seat assembly until the seat... The Uab Research Foundation

Nitrated lipids and methods of making and using thereof

Described herein are nitrated lipids and methods of making and using the nitrated lipids.... The Uab Research Foundation

Sumoylation assay and related reagents

Provided herein and methods and kits for identifying inhibitors of SUMOylation. The provided methods include contacting a candidate agent with (i) a SUMO-conjugating peptide comprising an N-terminal linker and a detectable tag, and (ii) a SUMO comprising a metal complex, under conditions that allow binding between the SUMO-conjugating peptide and... The Uab Research Foundation

Nitrite and nitrite-metheme therapy to detoxify stroma-free hemoglobin based blood substitutes

This disclosure relates to methods of using nitrite to detoxify stroma-free hemoglobin based blood substitutes. In particular, methods are described for using a blood substitute comprised of about equimolar amounts of nitrite and hemoglobin (e.g., nitrite-metHb) to treat, prevent, or ameliorate diseases of the blood in a subject, or as... The Uab Research Foundation

Hinged microfracture awls

In one embodiment, a hinged microfracture awl includes a handle, and a shaft that extends through and from the handle, the shaft being pivotally mounted to the handle with a hinge, wherein a distal end of the shaft includes a sharp tip adapted to pierce bone and a proximal end... The Uab Research Foundation

Msp nanopores and uses thereof

Provided herein are mutant single-chain Mycobacterium smegmatis porin (Msp) and uses thereof.... The Uab Research Foundation

Methods of reactivating a latent human immunodeficiency virus

Provided herein are methods of reactivating a latent Human Immunodeficiency Virus (HIV) infection in a cell or subject. The methods include contacting the cell with or administering to the subject one or more proteasome inhibitors, and contacting the cell with or administering to the subject one or more reactivating agents.... The Uab Research Foundation

Self-restoring crash cushions

In one embodiment, a self-restoring crash cushion including multiple diaphragms spaced along a length direction of the cushion, an elongated track adapted to be anchored to the ground that extends along the length direction under the cushion, the diaphragms being mounted to the track in a manner in which they... The Uab Research Foundation

Method for detecting an open-phase condition of a transformer

A method for detecting an open-phase condition of a transformer having a grounded-wye high voltage side connection including monitoring current flowing in a neutral connection on the high voltage side of the transformer in real time by voltage relaying and current relaying to identify an open phase condition signature in... The Uab Research Foundation








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