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The United States Of America As Represented By The Secretary Department Of Health x26 Human Servic
The United States Of America As Represented By The Secretary Department Of Health x26 Human Services
The United States Of America As Represented By The Secretary Department Of Health x26 Human Service

The United States Of America As Represented By The Secretary Department Of Health & Human Servic patents


Recent patent applications related to The United States Of America As Represented By The Secretary Department Of Health & Human Servic. The United States Of America As Represented By The Secretary Department Of Health & Human Servic is listed as an Agent/Assignee. Note: The United States Of America As Represented By The Secretary Department Of Health & Human Servic may have other listings under different names/spellings. We're not affiliated with The United States Of America As Represented By The Secretary Department Of Health & Human Servic, we're just tracking patents.

ARCHIVE: New 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 | Company Directory "T" | The United States Of America As Represented By The Secretary Department Of Health & Human Servic-related inventors


Magnetic resonance magnification imaging

One aspect of the present disclosure provides an imaging method including: specifying an imaging focus region on a subject to be imaged, applying radiofrequency pulses to the subject to interact with a magnetic field gradient, wherein the radiofrequency pulses successively bend magnetization phases of respective electromagnetic signals from the specified... The United States Of America As Represented By The Secretary Department Of Health & Human Servic

Use of (2r, 6r)-hydroxynorketamine, (s)-dehydronorketamine and other stereoisomeric dehydro and hydroxylated metabolites of (r,s)- ketamine in the treatment of depression and neuropathic pain

The disclosure also provides novel ketamine metabolite prodrugs. The disclosure provides methods of treating, bipolar depression, major depressive disorder, neuropathic and chronic pain, including complex regional pain synthetic pain disorder (CRPD) by administering a purified ketamine metabolite or a ketamine metabolite prodrug directly to patients in need of such treatment.... The United States Of America As Represented By The Secretary Department Of Health & Human Servic

Selective oxidation of 5-methylcytosine by tet-family proteins

The present invention provides for novel methods for regulating and detecting the cytosine methylation status of DNA. The invention is based upon identification of a novel and surprising catalytic activity for the family of TET proteins, namely TET1, TET2, TET3, and CXXC4. The novel activity is related to the enzymes... The United States Of America As Represented By The Secretary Department Of Health & Human Servic

Selective oxidation of 5-methylcytosine by tet-family proteins

The present invention provides for novel methods for regulating and detecting the cytosine methylation status of DNA. The invention is based upon identification of a novel and surprising catalytic activity for the family of TET proteins, namely TET1, TET2, TET3, and CXXC4. The novel activity is related to the enzymes... The United States Of America As Represented By The Secretary Department Of Health & Human Servic

Devices and methods for detection of counterfeit or adulterated products and/or packaging

Disclosed are devices and methods for detecting a counterfeit or adulterated products and/or packaging. The device (20) includes a plurality of light sources (28) configured to emit light at a plurality of different wavelengths onto an object, at least two image acquisition devices (34a, 34b) adapted to acquire first and... The United States Of America As Represented By The Secretary Department Of Health & Human Servic

Use of peptide-based inhibitors of the stat3-il10 pathway for treating bacterial infection and granulomatous disease

The invention provides a method of treating pathogenic bacterial infection (e.g., tuberculosis infection) in an animal comprising administering a peptide-based inhibitor of the STAT3-IL10 pathway or a nucleic acid encoding the peptide-based inhibitor to the animal. The invention also provides methods of treating chronic granulomatous disease and Wegener's granulomatosis in... The United States Of America As Represented By The Secretary Department Of Health & Human Servic

Peptide-based stat inhibitor

A peptide or peptidomimetic comprising the amino acid sequence of the second helix of a STAT protein, or a variant of such sequence, wherein the peptide or peptidomimetic comprises about 40 or fewer amino acids and binds to a STAT protein, as well as a method of inhibiting a STAT... The United States Of America As Represented By The Secretary Department Of Health & Human Servic

Selective oxidation of 5-methylcytosine by tet-family proteins

The present invention provides for novel methods for regulating and detecting the cytosine methylation status of DNA. The invention is based upon identification of a novel and surprising catalytic activity for the family of TET proteins, namely TET1, TET2, TET3, and CXXC4. The novel activity is related to the enzymes... The United States Of America As Represented By The Secretary Department Of Health & Human Servic

Pharmacodynamic assays

The present disclosure provides a method of monitoring total protein acetylation in a cell exposed to an HDAC inhibitor that involves first contacting a cell that has been exposed to an HDAC inhibitor with a plurality of reagents that each recognize and bind to a nuclear or cytoplasmic acetylated protein.... The United States Of America As Represented By The Secretary Department Of Health & Human Servic

Selective oxidation of 5-methylcytosine by tet-family proteins

The present invention provides for novel methods for regulating and detecting the cytosine methylation status of DNA. The invention is based upon identification of a novel and surprising catalytic activity for the family of TET proteins, namely TET1, TET2, TET3, and CXXC4. The novel activity is related to the enzymes... The United States Of America As Represented By The Secretary Department Of Health & Human Servic

Selective oxidation of 5-methylcytosine by tet-family proteins

The present invention provides for novel methods for regulating and detecting the cytosine methylation status of DNA. The invention is based upon identification of a novel and surprising catalytic activity for the family of TET proteins, namely TET1, TET2, TET3, and CXXC4. The novel activity is related to the enzymes... The United States Of America As Represented By The Secretary Department Of Health & Human Servic

Immunostimulatory combinations of tlr ligands and methods of use

The present invention provides immunostimulatory combinations of TLR ligands and therapeutic and/or prophylactic methods that include administering an immunostimulatory combination to a subject. In general, the immunostimulatory combinations described herein can provide an increased immune response compared to other immunostimulatory combinations and/or compositions.... The United States Of America As Represented By The Secretary Department Of Health & Human Servic

Selective oxidation of 5-methylcytosine by tet-family proteins

The present invention provides for novel methods for regulating and detecting the cytosine methylation status of DNA. The invention is based upon identification of a novel and surprising catalytic activity for the family of TET proteins, namely TET1, TET2, TET3, and CXXC4. The novel activity is related to the enzymes... The United States Of America As Represented By The Secretary Department Of Health & Human Servic

Selective detection of haemophilus influenzae

A process for detecting Haemophilus influenzae nucleic acid in a sample includes producing an amplification product by amplifying a Haemophilus influenzae nucleotide sequence and measuring the amplification product to detect Haemophilus influenzae in the sample. Some embodiments allow direct serotype determination in a single step assay. Also provided are reagents... The United States Of America As Represented By The Secretary Department Of Health & Human Servic

Methods and compositions for modulating immune tolerance

The instant invention provides methods and compositions for modulation of the immune system. Specifically, the present disclosure provides methods and compositions for increasing T cell mediated immune response useful in the treatment of cancer and chronic infection.... The United States Of America As Represented By The Secretary Department Of Health & Human Servic

Conductive and retrievable devices

In one embodiment, a method is disclosed in which a retrieval apparatus is coupled to a retrieval portion of an implantable device. The implantable device includes a plurality of expandable members each having a portion that comes into contact with a tissue of a subject when expanded. A force is... The United States Of America As Represented By The Secretary Department Of Health & Human Servic

Treatment or prevention of an intestinal disease or disorder

Disclosed are methods of treating or preventing an intestinal disease or disorder comprising administering to a subject a modulator of leucine rich repeat kinase 2 (LRRK2) in an amount effective to treat or prevent an intestinal disease or disorder and methods of determining the susceptibility or risk of a subject... The United States Of America As Represented By The Secretary Department Of Health & Human Servic








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