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Thomas Jefferson University
Thomas Jefferson University Hospitals Inc
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Thomas Jefferson University patents


Recent patent applications related to Thomas Jefferson University. Thomas Jefferson University is listed as an Agent/Assignee. Note: Thomas Jefferson University may have other listings under different names/spellings. We're not affiliated with Thomas Jefferson University, we're just tracking patents.

ARCHIVE: New 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 | Company Directory "T" | Thomas Jefferson University-related inventors


Composition and muscle repair and regeneration

The invention provides methods for muscle repair or regeneration comprising administering therapeutically effective amounts of RAR agonists or stem cells that are pretreated with contact with a RAR agonist to a subject at a site of muscle damage. Additionally, the invention provides compositions comprising RAR agonist treated stem cells and... Thomas Jefferson University

Par4 inhibitor therapy for patients with par4 polymorphism

Disclosed herein are methods for determining whether a PAR4 inhibitor should be administered to a human subject, the methods comprising administering a PAR4 inhibitor to a subject determined to have a “G” allele for a single-nucleotide polymorphism (SNP) at rs773902, and not administering a PAR4 inhibitor to a subject determined... Thomas Jefferson University

Implantable vital sign sensor

An implantable vital sign sensor including a housing including a first portion, the first portion defining a first open end, a second open end opposite the first end, and a lumen there through, the first portion being sized to be implanted substantially entirely within the blood vessel wall of the... Thomas Jefferson University

Treatment and prevention of thrombosis using an anti-mir

Disclosed are anti-miR compositions and methods of use of the same for treatment of or reducing the occurrence of thrombosis and thrombosis related diseases and disorders by reducing platelet activation.... Thomas Jefferson University

Specific expression of half-trna in cancers

The present invention relates to systems, devices and methods for diagnosing cancer. In various embodiments, the present invention provides a method for quantifying a 5′-htRNA; a method for quantifying a 3′-htRNA; a method for obtaining a DNA library of 5′-htRNAs and a DNA library of 5′-htRNAs obtained therefrom; and a... Thomas Jefferson University

Compositions and methods of using transfer rnas (trnas)

The present invention includes a method for analyzing tRNA fragments. In one aspect, the present invention includes Sa method of identifying a subject in need of therapeutic intervention to treat a disease or disease progression comprises characterizing the identity of tRNA fragments. The invention further includes diagnosing identifying or monitoring... Thomas Jefferson University

Development of masked therapeutic antibodies to limit off-target effects: application to anti-egfr antibodies

In one embodiment, a masked monoclonal antibody (mAb) is provided, the mAb, encoded by a nucleic acid sequence or an amino acid sequence molecule comprising a signal sequence, a masking epitope sequence, a linker sequence that is cleavable by a protease specific to a target tissue; and an antibody or... Thomas Jefferson University

Diagnosis and treatment of cancers with microrna located in or near cancer-associated chromosomal features

MicroRNA genes are highly associated with chromosomal features involved in the etiology of different cancers. The perturbations in the genomic structure or chromosomal architecture of a cell caused by these cancer-associated chromosomal features can affect the expression of the miR gene(s) located in close proximity to that chromosomal feature. Evaluation... Thomas Jefferson University

Compositions and methods for treating cancer with aberrant lipogenic signaling

The technology described herein relates to pinacolyl boronate substituted stilbenes for the treatment of cancers, e.g. cancers expressing abnormally high levels of SREBP1.... Thomas Jefferson University

Interleukin-15 superagonist significantly enhances graft-versus-tumor activity

The invention features therapies using an IL-15-based superagonist complex to effectively treat subjects with cancer.... Thomas Jefferson University

Implantable vital sign sensor

An implantable vital sign sensor including a housing including a first portion, the first portion defining a first open end, a second open end opposite the first end, and a lumen there through, the first portion being sized to be implanted substantially entirely within the blood vessel wall of the... Thomas Jefferson University

Implantable vital sign sensor

An implantable vital sign sensor including a housing including a first portion, the first portion defining a first open end, a second open end opposite the first end, and a lumen there through, the first portion being sized to be implanted substantially entirely within the blood vessel wall of the... Thomas Jefferson University

Methods and compositions for treating cancers and enhancing therapeutic immunity by selectively reducing immunomodulatory m2 monocytes

The present disclosure provides pharmaceutical compositions comprising nucleic acids capable of targeting IGF-1R expression in M2 cells. The present disclosure also provides methods for the selective reduction of M2 cells by targeting expression of IGF-1R in these cells. The present disclosure further provides methods for treating cancer and enhancing therapeutic... Thomas Jefferson University

Antibiotic drug release sheath

An implantable medical device having a sheath formed of a polymer material, wherein the sheath forms a reservoir attached to or around the implantable medical device, and wherein the reservoir is sealed with a biocompatible pressure responsive coating; wherein the biocompatible coating is stable for at least 7-day post implantation... Thomas Jefferson University

Compositions and methods for identifying and targeting cancer cells of alimentary canal origin

Screening and diagnostic reagents, kits and methods for primary and/or metastatic stomach or esophageal cancer are disclosed. Compositions for and methods of imaging and treating primary and/or metastatic stomach or esophageal cancer are disclosed. Vaccines compositions and methods of for treating and preventing primary and/or metastatic stomach or esophageal cancer... Thomas Jefferson University

Par4 inhibitor therapy for patients with par4 polymorphism

Disclosed herein are methods for determining whether a PAR4 inhibitor should be administered to a human subject, the methods comprising administering a PAR4 inhibitor to a subject determined to have a “G” allele for a single-nucleotide polymorphism (SNP) at rs773902, and not administering a PAR4 inhibitor to a subject determined... Thomas Jefferson University

4-((2-hydroxy-3-methoxybenzyl)amino)benzenesulfonamide derivatives as potent and selective inhibitors of 12-lipoxygenase

Human lipoxygenases (LOXs) are a family of iron-containing enzymes involved in catalyzing the oxidation of polyunsaturated fatty acids to provide the corresponding bioactive hydroxyeicosatetraenoic acid (HETE) metabolites. These eicosanoid signaling molecules are involved in a number of physiologic responses such as platelet aggregation, inflammation, and cell proliferation. Platelet-type 12-(S)-LOX (12-LOX)... Thomas Jefferson University








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This listing is an abstract for educational and research purposes is only meant as a recent sample of applications filed, not a comprehensive history. Freshpatents.com is not affiliated or associated with Thomas Jefferson University in any way and there may be associated servicemarks. This data is also published to the public by the USPTO and available for free on their website. Note that there may be alternative spellings for Thomas Jefferson University with additional patents listed. Browse our Agent directory for other possible listings. Page by FreshPatents.com

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