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Trustees Of Tufts College
Trustees Of Tufts College D b a Tufts University
Trustees Of Tufts College Office Of Technology And Industry Collaboration
Trustees Of Tufts College aka Tufts University
Trustees Of Tufts College_20100114
Trustees Of Tufts College Tufts University

Trustees Of Tufts College patents


Recent patent applications related to Trustees Of Tufts College. Trustees Of Tufts College is listed as an Agent/Assignee. Note: Trustees Of Tufts College may have other listings under different names/spellings. We're not affiliated with Trustees Of Tufts College, we're just tracking patents.

ARCHIVE: New 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 | Company Directory "T" | Trustees Of Tufts College-related inventors


Photoluminescent nanoparticles and their uses in detection or quantification of singlet oxygen

A composition, as well as methods using the composition, for detection or quantification of a molecule at a singlet state (e.g., singlet oxygen). The composition includes one or more nanoparticles, and the nanoparticle has an energy donor, an energy acceptor associated with the energy donor, and an energy transfer mechanism... Trustees Of Tufts College

Tissue-engineered silk organs

This invention relates to a lamellae tissue layer, comprising a grooved silk fibroin substrate comprising tissue-specific cells. The silk fibroin substrates provides an excellent means of controlling and culturing cell and extracellular matrix development. A multitude of lamellae tissue layers can be used to create a tissue-engineered organ, such as... Trustees Of Tufts College

Imaging system to characterize dynamic changes in cell and particle characteristics

An imaging system for a biological sample includes a sample container having at least one biological cell that is in contact with an interface surface of a container interface. The imaging system also includes illuminating optics that output a light beam aligned with a sample plane, the light beam being... Trustees Of Tufts College

Methods and compositions for preparing a silk microsphere

Provided herein relates to methods and compositions for preparing a silk microsphere and the resulting silk microsphere. In some embodiments, the methods and compositions described herein are all aqueous, which can be used for encapsulating an active agent in a silk microsphere, while maintaining activity of the active agent during... Trustees Of Tufts College

Peptidomimetic inhibitors of post-proline cleaving enzymes

Disclosed are inhibitors of post-proline cleavage enzymes, such as inhibitors of dipeptidyl peptidase IV, as well as pharmaceutical compositions thereof, and methods for using such inhibitors. In particular, the inhibitors are improved over those in the prior art by selection of particular classes of side chains in the P1 and/or... Trustees Of Tufts College

Fap-activated therapeutic agents, and uses related thereto

Disclosed are prodrugs of anthracyclines (such as doxorubicin) and derivatives thereof that are selectively cleaved and activated by fibroblast activating protein (FAP). The prodrugs are useful for targeted delivery of “warhead” anthracycline or anthracycline derivative to FAP-expressing tissues, including cancer (e.g., solid tumors). Also provided are pharmaceutical compositions comprising the... Trustees Of Tufts College

Methods and kits for removing organic pollutants from a contaminated sample

Methods and kits for the removal of organic contaminants from contaminated samples are generally provided. In some embodiments, the methods and kits comprise a surfactant and adsorbent particles.... Trustees Of Tufts College

Concentrated aqueous silk fibroin solution and use thereof

The present invention provides for concentrated aqueous silk fibroin solutions and an all-aqueous mode for preparation of concentrated aqueous fibroin solutions that avoids the use of organic solvents, direct additives, or harsh chemicals. The invention further provides for the use of these solutions in production of materials, e.g., fibers, films,... Trustees Of Tufts College

Devices for wound healing

The present invention provides devices and methods for improving wound healing, in particular, in diabetic subjects.... Trustees Of Tufts College

Compositions and methods for stabilization of active agents

Provided herein are methods and compositions for stabilization of active agents. The active agents are distributed, mixed or embedded in a silk fibroin matrix, thereby retaining the bioactivity of the active agents upon storage and/or transportation. In some embodiments, the storage-stable vaccine-silk compositions are also provided herein.... Trustees Of Tufts College

Stable analogs of peptide and polypeptide therapeutics

The present invention relates to compositions of peptide and polypeptide analogs that are resistant to proteolysis, pharmaceutical uses thereof, and methods of preparation thereof.... Trustees Of Tufts College

Smart pro-drugs of serine protease inhibitors

The present invention relates to prodrugs of protease inhibitors, such as inhibitors of the proteosome, DPP IV, FAPα and the like. These“pro-inhibitors” are activated, i.e., cleaved, by an “activated protease” to release an active inhibitor moiety in proximity to a “target protease”. The identity of activating protease and target protease... Trustees Of Tufts College

Methods, compositions and kits for treating a subject using a recombinant heteromultimeric neutralizing binding protein

Methods, compositions and kits are provided for treating a subject exposed to or at risk for exposure to a disease agent using a pharmaceutical composition including at least one recombinant heteromultimeric neutralizing binding protein including two or multiple binding regions, such that the binding regions are not identical, and each... Trustees Of Tufts College

Target analyte sensors utilizing microspheres

A microsphere-based analytic chemistry system and method for making the same is disclosed in which microspheres or particles carrying bioactive agents may be combined randomly or in ordered fashion and dispersed on a substrate to form an array while maintaining the ability to identify the location of bioactive agents and... Trustees Of Tufts College

Methods for detecting target analytes and enzymatic reactions

A microsphere-based analytic chemistry system and method for making the same is disclosed in which microspheres or particles carrying bioactive agents may be combined randomly or in ordered fashion and dispersed on a substrate to form an array while maintaining the ability to identify the location of bioactive agents and... Trustees Of Tufts College

Compositions and methods for ocular delivery of a therapeutic agent

Embodiments of various aspects described herein are directed to silk-based compositions for ocular delivery of at least one active agent, e.g., at least one therapeutic agent and methods of using the same. In some embodiments, the silk-based compositions can provide sustained release of at least one therapeutic agent to at... Trustees Of Tufts College

Methods for determining the concentration of an analyte in solution

Disclosed is a method for measuring the concentration of an analyte or analytes in a solution. Although the methods can be conducted using a number of different assay formats, in one embodiment, the assays are conducted in reaction vessels defined, at least in part, by the distal ends of fiber... Trustees Of Tufts College

Fap-activated therapeutic agents, and uses related thereto

Disclosed are prodrugs of anthracyclines (such as doxorubicin) and derivatives thereof that are selectively cleaved and activated by fibroblast activating protein (FAP). The prodrugs are useful for targeted delivery of “warhead” anthracycline or anthracycline derivative to FAP-expressing tissues, including cancer (e.g., solid tumors). Also provided are pharmaceutical compositions comprising the... Trustees Of Tufts College

Fap-activated therapeutic agents, and uses related thereto

Disclosed are prodrugs of therapeutic or imaging agents, which prodrugs are selectively cleaved by fibroblast activating protein (FAP) to release the agents. Upon cleavage by FAP of the FAP substrate, the prodrug releases the agent in its active form or in a form that is readily metabolized to its active... Trustees Of Tufts College

Radioactive monolayer surface coating

Disclosed are compositions including a film enriched with a radioisotope relative to its natural abundance, wherein the film has a thickness of one to ten atomic or molecular layers, decay of the radioisotope comprises emission of electrons, and a majority of the emitted electrons have an energy less than or... Trustees Of Tufts College

Reagent-controlled stereoselective glycosylation

Provided are methods for the efficient stereoselective formation of glycosidic bonds, without recourse to prosthetic or directing groups.... Trustees Of Tufts College

System, multi-input multi-output communications over per-transmitter power-constrained channels

A multipath communication system forms a complex weighted compound signal for transmission through a channel environment wherein the compound signal includes a complex variable weighted compound signal related to a count of available antennas, a power constraint related to each said antenna, and a channel state characteristic.... Trustees Of Tufts College

Methods and arrays for target analyte detection and determination of target analyte concentration in solution

Arrays of single molecules and methods of producing an array of single molecules are described. Arrays with defined volumes between 10 attoliters and 50 picoliters enable single molecule detection and quantitation.... Trustees Of Tufts College

Injectable silk fibroin foams and uses thereof

The inventions provided herein relate to compositions, methods, delivery devices and kits for repairing or augmenting a tissue in a subject. The compositions described herein can be injectable such that they can be placed in a tissue to be treated with a minimally-invasive procedure (e.g., by injection). In some embodiments,... Trustees Of Tufts College

 new patent  Non-neuroinvasive viruses and uses thereof

Provided herein are compositions and methods for vaccination and research applications. In particular, provided herein are non-neuroinvasive herpesviruses and alpha herpesviruses and uses thereof.... Trustees Of Tufts College








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