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Universit xc9 De Montr xc9 al patents


Recent patent applications related to Universit xc9 De Montr xc9 al. Universit xc9 De Montr xc9 al is listed as an Agent/Assignee. Note: Universit xc9 De Montr xc9 al may have other listings under different names/spellings. We're not affiliated with Universit xc9 De Montr xc9 al, we're just tracking patents.

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Pyrimido[4,5-b]indole derivatives and use thereof in the expansion of hematopoietic stem cells

Pyrimido[4,5-b]indole derivatives are provided. These compounds are useful to expand hematopoietic stem cell populations, particularly, human hematopoietic stem cell populations. The compounds are also useful in the medical treatment of diseases that involve hematopoietic stem cells.... Universit xc9 De Montr xc9 al

Markers of poor prognosis acute myeloid leukemias (amls) and uses thereof

Genes exhibiting specific mutational and/or transcriptional patterns in poor prognosis AMLs, such as EVI1-rearranged acute myeloid leukemias (EVI1-r AMLs), relative to other types of AMLs and/or normal CD34+ cells, are disclosed. The use of these mutational and/or transcriptional patterns, for example the expression level of the PRKC Apoptosis WT1 Regulator... Universit xc9 De Montr xc9 al

Biosensor based on g-beta-gamma-interacting proteins to monitor g-protein activation

Resonance energy transfer (RET)- or protein-fragment complement assay (PCA)-based biosensors useful for assessing the activity of G-proteins are described. These biosensors are based on the competition between the Got subunit and a Gβγ interacting protein (βγ IP) for the binding to the Gβγ dimer. These biosensors comprises (1) a βγ... Universit xc9 De Montr xc9 al

Processes for producing limxo4 and products thereof

There is provided a process for producing LiMXO4, comprising the steps of reacting a source of lithium, a source of M, and a source of X together, in a melted state at a reaction temperature between 900 to 1450 C, in the presence of an excess of (A) a solid-solid... Universit xc9 De Montr xc9 al

Method for identifying novel minor histocompatibility antigens

A novel method for human minor histocompatibility antigen (MiHA) discovery, novel MiHAs identified using this method, as well as uses of the novel MiHAs, are described. One of the features of the novel method is the inclusion of personalized translated transcriptome and/or exome in the database used for peptide identification... Universit xc9 De Montr xc9 al

Compounds and use thereof in the expansion of hematopoietic stem cells and/or hematopoietic progenitor cells

Compounds of general formula or salts or prodrugs thereof, are provided and described herein. The compounds are useful to expand hematopoietic stem cell and/or hematopoietic progenitor cell populations. Particularly, the hematopoietic cells are human cells. The compounds are also useful in the medical treatment of hematopoietic disorder/malignancy, an autoimmune disease... Universit xc9 De Montr xc9 al

Systems and methods for the monitoring of protein complex formation in cells

Described herein is a bioluminescence resonance energy transfer (BRET) based system and method to monitor ternary complex formation in real-time in live cells with high sensitivity and accuracy. This system transfers energy simultaneously between a luciferase donor and intermediate and terminal acceptors, appropriately chosen to also enable transfer from the... Universit xc9 De Montr xc9 al








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