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Universit xc9 Laval patents

Recent patent applications related to Universit xc9 Laval. Universit xc9 Laval is listed as an Agent/Assignee. Note: Universit xc9 Laval may have other listings under different names/spellings. We're not affiliated with Universit xc9 Laval, we're just tracking patents.

ARCHIVE: New 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 | Company Directory "U" | Universit xc9 Laval-related inventors

Methods for producing dopaminergic neurons and uses thereof

The present application relates to a stem cell, a precursor or progenitor cell in which Plexin C1 has been inactivated, a dopaminergic (DA) neuron in which Plexin C1 has been inactivated, methods of preparing same and uses thereof for the treatment of Parkinson's disease.... Universit xc9 Laval

Tdp-43-binding polypeptides useful for the treatment of neurodegenerative diseases

Provided herein are antigen-binding constructs such as antibodies that bind to the RRM-1 domain of TDP-43. The antigen-binding constructs are capable of blocking the interaction of TDP-43 with NF-κB in cells. Also provided herein are method of using the antigen-binding constructs in the treatment of diseases associated with TPD-43 proteinopathy,... Universit xc9 Laval

Methods and products for increasing frataxin levels and uses thereof

Methods and products (e.g., recombinant proteins) are described for increasing frataxin expression/levels in a cell, as well as uses of such methods and products, for example for the treatment of Friedreich ataxia in a subject suffering therefrom.... Universit xc9 Laval

Microrna-132/212 for the treatment of neurodegenerative disorders

The present relates to the use of miRNA-132/212 mimics or activators comprising a doubled stranded ribonucleic acid molecule comprising a seed region sequence of miRNA-132 or miRNA-212, a spacer, a stabilizing sequence, and a carrier for the treatment of neurodegenerative disorders, including Alzheimer's disease, Tauopathies, Amyotrophic lateral sclerosis, Parkinson's disease,... Universit xc9 Laval

Prevention and treatment of alzheimer's disease by genome editing using the crispr/cas system

Methods and products related to genome editing using the CRISPR/Cas9 system to introduce an A673T substitution into an APP gene, such as guide RNAs and recombinant proteins, are described for decreasing APP levels produced by a cell, and use for the treatment of Alzheimer's disease and/or age-related cognitive decline in... Universit xc9 Laval

Built-up system, connector thereof, and making same

A connector for connecting a wood substrate to a concrete layer. The connector comprising a shank adapted to engagement with a bore in the wood substrate with a length of the shank aligned with a central axis of the bore, the shank having at least an external portion made of... Universit xc9 Laval

Fluorescent nanosensors and uses thereof

Fluorescent nanosensors for extracellular ion concentration measurements are disclosed herein. More specifically, a fluorescent nanosensor for extracellular ion measurements comprising a photoluminescent nanostructure disposed on a substrate surface is disclosed. The photoluminescent nanostructure comprises a fluorescent metallic core-silica shell containing nanoparticle, wherein the fluorescent silica shell comprises a fluorophore dispersed... Universit xc9 Laval

Method for use of homopiperazinium compounds in the treatment of cancer

wherein R1 and R2 are independently alkyl of 1 to 6 carbon atoms or cycloalkyl of 3 to 6 carbon atoms, Xa is CH or N, Ya is hydrogen or a substituent, each of which is independently selected; n is an integer from 1 to 5, J is a counter... Universit xc9 Laval

Fluidic centripetal device

A fluidic centripetal apparatus for testing components of a biological material in a fluid is presented. The fluidic centripetal device is adapted to be received within a rotatable holder. The apparatus comprises a fluidic component layer having fluidic features on at least a front face and a bottom component layer... Universit xc9 Laval

Writing of high mechanical strength fiber bragg gratings using ultrafast pulses and a phase mask

Methods and systems for writing a Bragg grating along a grating region of an optical fiber through a polymer coating of the optical fiber are provided. A light beam of ultrafast optical pulses is impinged on the grating region, the ultrafast optical pulses being characterised by writing wavelength at the... Universit xc9 Laval

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