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Universite Paris Diderot Paris 7 patents


Recent patent applications related to Universite Paris Diderot Paris 7. Universite Paris Diderot Paris 7 is listed as an Agent/Assignee. Note: Universite Paris Diderot Paris 7 may have other listings under different names/spellings. We're not affiliated with Universite Paris Diderot Paris 7, we're just tracking patents.

ARCHIVE: New 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 | Company Directory "U" | Universite Paris Diderot Paris 7-related inventors


Mutant smoothened and methods of using the same

The emergence of mutations in tyrosine kinases following treatment of cancer patients with molecular-targeted therapy represents a major mechanism of acquired drug resistance. Here, mutations in the serpentine receptor, Smoothened (SMO) are described, which result in resistance to a Hedgehog (Hh) pathway inhibitor, such as in medulloblastoma. Amino acid substitutions... Universite Paris Diderot Paris 7

Polypeptides for engineering integrase chimeric proteins and their use in gene therapy

The present invention relates to polypeptide for engineering integrase chimeric proteins and their use in gene therapy. In particular, the present invention relates to a polypeptide which comprises the amino acid sequence ranging from the amino acid residue at position 617 to the amino acid residue at position 622 in... Universite Paris Diderot Paris 7

Selective porphyrin-catalyzed electrochemical reduction of co2 into co in water

The present invention relates to the use of complexes of water soluble porphyrins of formula (I) below wherein R1 to R10 and R1′ to R10′ are as defined in claim 1, with iron as catalysts for the selective electrochemical reduction of CO2 into CO, electrochemical cells comprising them, and methods... Universite Paris Diderot Paris 7

Human monoclonal antibodies against orexin receptor type 1

The present disclosure relates to human monoclonal antibodies against orexin receptor type 1 (OX1R, hyprocretin 1) and uses thereof for the treatment of cancer. The antibodies are characterized by their CDRs: NYYMN, YISGSSRNIYYADFVKG, SNYDGMDV (Heavy chain) and AGTSSDVGGSNYVS, PGKAP, SSYTYYSTRV (Light Chain)) or the CDRS having at least 50% or... Universite Paris Diderot Paris 7

Methods and pharmaceutical compositions using orexins (oxa, oxb) for the treatment of prostate cancers

The present disclosure relates to methods and pharmaceutical compositions for the treatment of prostate cancers. In particular, the present invention relates to an OX1R agonist for use in the treatment of prostate cancer in a subject in need thereof.... Universite Paris Diderot Paris 7

Porous polysaccharide scaffold comprising nano-hydroxyapatite and use for bone formation

The present invention relate to three dimensional porous polysaccharide matrices able to induce mineralisation of a tissue in osseous site, as well as in non-osseous site, in the absence of stem cells or growth factors.... Universite Paris Diderot Paris 7

Polypeptides for the treatment of angiogenesis or lymphangiogenesis-related diseases

The present invention relates to polypeptides for the treatment of angiogenesis or lymphangiogenesis-related diseases. In particular, the present invention relates to a a polypeptide which comprises or consists of a sequence of at least 5 consecutive amino acids in SEQ ID NO: 1 and which comprises at least one amino... Universite Paris Diderot Paris 7

Time-controlled glucose releasing hydrogels and applications thereof

The present invention relates generally to a hydrogel releasing glucose in a time-controlled manner, to medical applications thereof, and to a method for preparing said hydrogel.... Universite Paris Diderot Paris 7

Methods and pharmaceutical compositions for the treatment of erythropoietic protoporphyria

The present invention relates to methods and pharmaceutical compositions for the treatment of Erythropoietic Protoporphyria. In particular, the present invention relates to a method for increasing the amount of functional FECH in a erythroid cell carrying the hypomorphic allele IVS3 48C/T (rs2272783) in trans to a deleterious mutation in the... Universite Paris Diderot Paris 7

Population of immunoregulatory t cells specific for an irrelevant antigen and uses thereof for preventing or treating immune diseases

The present invention relates methods and compositions for preventing or treating various immune diseases including graft-versus-host disease (GVHD) using populations or compositions of immunoregulatory T cells specific for an irrelevant antigen; such cells being activated in vivo by a simultaneous, separate or sequential administration of said antigen.... Universite Paris Diderot Paris 7

Methods for treating neuromuscular junction-related diseases

The present invention relates to methods for treating neuromuscular junction-related diseases. In particular, the present invention relates to a method of treating a neuromuscular junction-related disease in a subject in need thereof comprising ad ministering the subject with a therapeutically effective amount of at least one inhibitor of glycogen synthase... Universite Paris Diderot Paris 7

Pharmaceutical compositions comprising agonists of orexin-1 receptor ox1r for the treatment of inflammatory bowel diseases

The present invention relates to methods and pharmaceutical compositions for the treatment of inflammatory bowel diseases. The presents methods relates to a method of treating an inflammatory bowel disease in a subject in need thereof comprising administering the subject with a therapeutically effective amount of at least one OX1R agonist.... Universite Paris Diderot Paris 7

Method for the continuous evaluation of the ventriculo-aortic coupling of at-risk patients by analysis of pressure-flow loops

The invention relates to the field of cardiovascular resuscitation and, more specifically, it concerns a novel method of monitoring the ventriculo-aortic coupling of at-risk patients on the basis of the aortic pressure/flow loop of the patient and the zoning of this loop.... Universite Paris Diderot Paris 7

Optical device for measuring the position of an object

The invention relates to an optical device for measuring the position of an object along a first axis, the object being subjected to light radiations emitted by a light source. The optical device comprises: an imaging system comprising an objective for collecting light radiations diffused by the object, the imaging... Universite Paris Diderot Paris 7

Synergistic combination of biomarkers for detecting and assessing hepatic fibrosis

The application relates to hepatic fibrosis, specifically to hepatic fibrosis that may appear in a patient infected with one or more hepatitis viruses and/or who is suffering from hepatitis, specifically chronic hepatitis. The application provides methods and means for determining the stage (or degree) of hepatic fibrosis of such a... Universite Paris Diderot Paris 7

Methods for predicting acute rejection in heart recipients

The present invention relates to method for predicting acute rejection in heart recipients. In particular, the present invention relates to a method for predicting acute rejection in a heart recipient comprising the steps consisting of i) determining the expression level (ELi) of at least one miRNAi selected from the group... Universite Paris Diderot Paris 7

Composition comprising a combination of dna methylation inhibitor and a vitamin d receptor agonist for the treatment of drug resistant cancer or for the prevention of tumor relapse

The present invention concerns a combination of (i) a DNA methylation inhibitor, and (ii) a Vitamin D receptor agonist, for simultaneous or sequential use in the treatment of a drug resistant cancer and/or in prevention of tumor relapse in a patient suffering from cancer. The present invention also relates to... Universite Paris Diderot Paris 7

Detection of platelet-derived shed cd31

The present invention relates to various soluble forms of CD31, including a novel form which is shed by activated platelets and released into the circulation. Methods for detecting said soluble forms of CD31 are disclosed, as are methods of specifically 1 detecting said platelet-derived shed CD31 and the use of... Universite Paris Diderot Paris 7

Porphyrin molecular catalysts for selective electrochemical reduction of co2 into co

The present invention relates to porphyrins of formula (I): wherein R1 to R6, R1′ to R6′, X, X′ Y and Y′ are as described in claim 1. The invention also relates to complexes of said porphyrins with transition metals, in particular iron, preferably as Fe(III) or Fe(0) complex, and salts... Universite Paris Diderot Paris 7

Use of cranberry proanthocyanidin for treatment of oropharyngeal bacterial colonization

The present invention relates to a method for preventing Gram-negative bacterial colonization of an oropharyngeal material, the said method comprising bringing into contact a composition comprising a cranberry-derived proanthocyanidin extract on at least a part of the surface area of the said material.... Universite Paris Diderot Paris 7

Cd300a receptors as virus entry cofactors

The present invention concerns an inhibitor of an interaction between CD300a and an aminophospholipid for use in preventing or treating a virus infection by inhibition of the interaction between CD300a and viral aminophospholipid.... Universite Paris Diderot Paris 7








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