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University Of Florida Research Foundation Incorporated patents


Recent patent applications related to University Of Florida Research Foundation Incorporated. University Of Florida Research Foundation Incorporated is listed as an Agent/Assignee. Note: University Of Florida Research Foundation Incorporated may have other listings under different names/spellings. We're not affiliated with University Of Florida Research Foundation Incorporated, we're just tracking patents.

ARCHIVE: New 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 | Company Directory "U" | University Of Florida Research Foundation Incorporated-related inventors


Raav-guanylate cyclase compositions and methods for treating leber's congenital amaurosis-1 (lca1)

Disclosed are viral vector compositions comprising polynucleotide sequences that express one or more biologically-active mammalian guanylate cyclase proteins. Also disclosed are methods for their use in preventing, treating, and/or ameliorating at least one or more symptoms of a disease, disorder, abnormal condition, or dysfunction resulting at least in part from... University Of Florida Research Foundation Incorporated

Use of anoctamin as a biomarker for radiation biodosimetry

In one embodiment, the present invention pertains to the use of anoctamin as a biomarker for determining radiation dosimetery. In certain embodiments, the present invention relates to the use of anoctamin as a biomarker for diagnosing the presence of radiation toxicity in a subject who has been exposed to ionizing... University Of Florida Research Foundation Incorporated

Organic microgel system for 3d printing of silicone structures

An organic microgel system as support material for 3D printing of soft materials such as silicone and methods for manufacturing and using the organic microgel system are disclosed. In some embodiments, the organic microgel system comprises a plurality of microgel particles formed by blending a di-block copolymer and a tri-block... University Of Florida Research Foundation Incorporated

Optical privatizing device, system and use

Embodiments are directed to an optical privatizing device (100), system and methods of use. The device includes a removable frame (101) removably attachable to a sensor housing (1A). A device includes a blurring lens (130) coupled to the removable frame (101) and configured to optically modify light passing to a... University Of Florida Research Foundation Incorporated

Artificial self-sufficient cytochrome p450s

The disclosure relates to the field of fusion proteins. In some aspects, the invention relates to artificial fusion proteins comprising cytochrome P450 enzymes linked to reductase enzymes and uses thereof. In some aspects, the disclosure relates to compounds produced by artificial cytochrome P450 enzymes.... University Of Florida Research Foundation Incorporated

Site-specific integrating recombinant aav vectors for gene therapy and improved production methods

Provided herein are methods of site-specific integration of a heterologous sequence into a host genome (e.g., by administering a recombinant adeno-associated virus (rAAV) to a host cell in the presence of a Rep protein), and methods for treating diseases and disorders by delivering an rAAV that comprises a nucleic acid... University Of Florida Research Foundation Incorporated

Mems capacitive shear sensor system having an interface circuit

A sensor system comprising a Micro-Electro-Mechanical Systems (MEMS)-based capacitive floating element shear stress sensor, the associated packaging, and the interface circuitry required for operation as an instrumentation-grade sensing system is disclosed herein. One implementation of the interface circuitry is an analog synchronous modulation/demodulation scheme enabling time-resolved measurements of both mean... University Of Florida Research Foundation Incorporated

Capsid-modified raav vectors and methods of use

Disclosed are tyrosine-modified rAAV vectors, as well as infectious virions, compositions, and pharmaceutical formulations that comprise them. Also disclosed are methods of preparing and methods for using the disclosed tyrosine-phosphorylated capsid protein mutant rAAV vectors in a variety of diagnostic and therapeutic applications including in vivo and ex vivo gene... University Of Florida Research Foundation Incorporated

Mems capacitive shear sensor system having an interface circuit

A sensor system comprising a Micro-Electro-Mechanical Systems (MEMS)-based capacitive floating element shear stress sensor, the associated packaging, and the interface circuitry required for operation as an instrumentation-grade sensing system is disclosed herein. One implementation of the interface circuitry is an analog synchronous modulation/demodulation scheme enabling time-resolved measurements of both mean... University Of Florida Research Foundation Incorporated

Common-mask guided image reconstruction for enhanced four-dimensional cone-beam computed tomography

A system for constructing images representing a 4DCT sequence of an object from a plurality of projections taken from a plurality of angles with respect to the object and at a plurality of times, first portions of the object being less static than second portions of the object. The system... University Of Florida Research Foundation Incorporated

Context-sensitive flow interrupter and drainage outflow optimization system

Embodiments of the invention provide methods and devices for improved drainage systems and tubing. In one embodiment, a context-sensitive flow interrupter is provided that inhibits or facilitates flow of fluid when engaged with a mating holder. In another embodiment, outflow is optimized through control of the pressure in gas pockets... University Of Florida Research Foundation Incorporated

Recombinant aav production in mammalian cells

The present invention includes methods and compositions for the production of high titer recombinant Adeno-Associated Virus (rAAV) in a variety of mammalian cells. The disclosed rAAV are useful in gene therapy applications. Disclosed methods based on co-infection of cells with two or more replication-defective recombinant herpes virus (rHSV) vectors are... University Of Florida Research Foundation Incorporated

Virtual barricade for radiation inspection of predefined paths

A method of operating a radiation inspection system includes identifying a regulatory region along a predetermined path where public access is restricted based upon criteria other than radiation exposure, measuring a radiation exposure level from a radiation source of the radiation inspection system within the regulatory region, irradiating a target... University Of Florida Research Foundation Incorporated

Rotating radiation shutter collimator

A shutter for controlling radiation exposure includes a rotatable member. The rotatable member is rotatable between an open position and a closed position. The rotatable member includes a passageway, wherein the passageway is positioned to receive radiation in the open position and is not positioned to receive radiation in the... University Of Florida Research Foundation Incorporated

Three-dimensional image reconstruction using transmission and scatter radiography methods

A method for image reconstruction includes irradiating an object with a beam of radiation from a radiation source, measuring an attenuated portion of the beam, estimating a density of the object, determining a predicted attenuated portion of the beam using the density estimate, and iteratively adjusting the density estimate of... University Of Florida Research Foundation Incorporated

Nanocomposite magnetic materials for magnetic devices and systems

Nanocomposite magnetic materials, methods of manufacturing nanocomposite magnetic materials, and magnetic devices and systems using these nanocomposite magnetic materials are described. A nanocomposite magnetic material can be formed using an electro-infiltration process where nanomaterials (synthesized with tailored size, shape, magnetic properties, and surface chemistries) are infiltrated by electroplated magnetic metals... University Of Florida Research Foundation Incorporated

High electron mobility transistors with improved heat dissipation

III-nitride based high electron mobility transistors (HEMTs), such as AlGaN/GaN HEMTs on Silicon substrates, with improved heat dissipation are described herein. A semiconductor device having improved heat dissipation may include a substrate having a top surface and a bottom surface, a nucleation layer on the top surface of the substrate,... University Of Florida Research Foundation Incorporated

Interactive mixed reality system and uses thereof

An interactive mixed reality simulator is provided that includes a virtual 3D model of internal or hidden features of an object; a physical model or object being interacted with; and a tracked instrument used to interact with the physical object. The tracked instrument can be used to simulate or visualize... University Of Florida Research Foundation Incorporated

Wireless power transfer via electrodynamic coupling

Wireless power transmission (WPT) systems are provided. According to an embodiment, the WPT system uses one or more power transmitting coils and a receiver for electromagnetically coupled wireless power transfer. The electrodynamic receiver can be in the form of an electrodynamic transducer where a magnet is allowed to oscillate near... University Of Florida Research Foundation Incorporated

Protein biomarkers for acute, subacute and chronic traumatic injuries of the central nervous system

Proteins that are differentially expressed or elevated in tissue and biofluids after central nervous system injuries are described. Elevated or reduced levels of the proteins, alone or in various combinations or ratios, can be used to assess severity of central nervous system injury (CNS injury) including traumatic brain injury (TBI),... University Of Florida Research Foundation Incorporated

Screening for neurological disease using speech articulation characteristics

Detection of neurological diseases such as Parkinson's disease can be accomplished through analyzing a subject's speech for acoustic measures based on human factor cepstral coefficients (HFCC). Upon receiving a speech sample from a subject, a signal analysis can be performed that includes identifying articulation range and articulation rate using HFCC... University Of Florida Research Foundation Incorporated

Capacitive microphone with integrated cavity

A capacitive microphone and method of fabricating the same are provided. One or more holes can be formed in a first printed circuit board (PCB). A diaphragm can be surface micro-machined onto an interior surface of the first PCB at a region having the one or more holes. Interface electronics... University Of Florida Research Foundation Incorporated

Macrocyclic therapeutic agents, methods of manufacture, and methods of treatment

The instant invention describes macrocyclic compounds having therapeutic activity, and the mechanism and methods of treating disorders such as autoimmune diseases, inflammation, and cancer, tumors and cell proliferation related disorders.... University Of Florida Research Foundation Incorporated

Lipoteichoic acid from lactobacilli as a potent immune stimulatory adjuvant for vaccine development

The present invention provides compositions and methods useful for vaccination and generating CD8+ T lymphocyte immune memory against one or more antigens utilizing lipoteichoic acid.... University Of Florida Research Foundation Incorporated

System and internal inspection of rail components

An internal imaging system has a radiation source and a plurality of detectors positioned to receive portions of the plurality of collimated beams that have been attenuated by interaction with the target. The radiation source is configured to irradiate a target with a plurality of collimated beams of radiation. Two... University Of Florida Research Foundation Incorporated

Materials and methods for the treatment of latent viral infection

The subject invention pertains to materials and methods for the treatment of latent viral infections.... University Of Florida Research Foundation Incorporated

Method of treating or retarding the development of blindness

A method for treating an ocular disorder characterized by the defect or absence of a normal gene in the ocular cells of a human or animal subject involves administering to the subject by subretinal injection an effective amount of a recombinant adeno-associated virus carrying a nucleic acid sequence encoding the... University Of Florida Research Foundation Incorporated








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