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University Of Florida Research Foundation patents


Recent patent applications related to University Of Florida Research Foundation. University Of Florida Research Foundation is listed as an Agent/Assignee. Note: University Of Florida Research Foundation may have other listings under different names/spellings. We're not affiliated with University Of Florida Research Foundation, we're just tracking patents.

ARCHIVE: New 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 | Company Directory "U" | University Of Florida Research Foundation-related inventors


Novel small molecule anticancer agents

The invention relates to methods of treating cell proliferative disorders. The invention further relates to pharmaceutical compositions for treating cell proliferative disorders, especially cancer.... University Of Florida Research Foundation

Mitigation of contamination of electroplated cobalt-platinum films on substrates

Various embodiments to mitigate the contamination of electroplated cobalt-platinum films on substrates are described. In one embodiment, a device includes a substrate, a titanium nitride diffusion barrier layer formed upon the substrate, a titanium layer formed upon the titanium nitride diffusion barrier layer, a platinum seed layer, and a cobalt-platinum... University Of Florida Research Foundation

Biisoquinoline compounds and methods of treatment

The instant invention describes biisoquinoline compounds having therapeutic activity, and methods of treating dis-orders such as cancer, tumors and cell proliferation related disorders, or affect cell differentiation, dedifferentiation or transdifferentiation.... University Of Florida Research Foundation

Mitochondrial-targeted antioxidants protect against mechanical ventilation-induced diaphragm dysfunction and skeletal muscle atrophy

The present disclosure provides methods and compositions for preventing or treating MV-induced or disuse-induced skeletal muscle infirmities in a mammalian subject. The methods further include administering to the subject an effective amount of an aromatic-cationic peptide.... University Of Florida Research Foundation

Raav-guanylate cyclase compositions and methods for treating leber's congenital amaurosis-1 (lca1)

Disclosed are viral vector compositions comprising polynucleotide sequences that express one or more biologically-active mammalian guanylate cyclase proteins. Also disclosed are methods for their use in preventing, treating, and/or ameliorating at least one or more symptoms of a disease, disorder, abnormal condition, or dysfunction resulting at least in part from... University Of Florida Research Foundation

Use of anoctamin as a biomarker for radiation biodosimetry

In one embodiment, the present invention pertains to the use of anoctamin as a biomarker for determining radiation dosimetery. In certain embodiments, the present invention relates to the use of anoctamin as a biomarker for diagnosing the presence of radiation toxicity in a subject who has been exposed to ionizing... University Of Florida Research Foundation

Organic microgel system for 3d printing of silicone structures

An organic microgel system as support material for 3D printing of soft materials such as silicone and methods for manufacturing and using the organic microgel system are disclosed. In some embodiments, the organic microgel system comprises a plurality of microgel particles formed by blending a di-block copolymer and a tri-block... University Of Florida Research Foundation

Optical privatizing device, system and use

Embodiments are directed to an optical privatizing device (100), system and methods of use. The device includes a removable frame (101) removably attachable to a sensor housing (1A). A device includes a blurring lens (130) coupled to the removable frame (101) and configured to optically modify light passing to a... University Of Florida Research Foundation

Artificial self-sufficient cytochrome p450s

The disclosure relates to the field of fusion proteins. In some aspects, the invention relates to artificial fusion proteins comprising cytochrome P450 enzymes linked to reductase enzymes and uses thereof. In some aspects, the disclosure relates to compounds produced by artificial cytochrome P450 enzymes.... University Of Florida Research Foundation

Site-specific integrating recombinant aav vectors for gene therapy and improved production methods

Provided herein are methods of site-specific integration of a heterologous sequence into a host genome (e.g., by administering a recombinant adeno-associated virus (rAAV) to a host cell in the presence of a Rep protein), and methods for treating diseases and disorders by delivering an rAAV that comprises a nucleic acid... University Of Florida Research Foundation

Mems capacitive shear sensor system having an interface circuit

A sensor system comprising a Micro-Electro-Mechanical Systems (MEMS)-based capacitive floating element shear stress sensor, the associated packaging, and the interface circuitry required for operation as an instrumentation-grade sensing system is disclosed herein. One implementation of the interface circuitry is an analog synchronous modulation/demodulation scheme enabling time-resolved measurements of both mean... University Of Florida Research Foundation

Capsid-modified raav vectors and methods of use

Disclosed are tyrosine-modified rAAV vectors, as well as infectious virions, compositions, and pharmaceutical formulations that comprise them. Also disclosed are methods of preparing and methods for using the disclosed tyrosine-phosphorylated capsid protein mutant rAAV vectors in a variety of diagnostic and therapeutic applications including in vivo and ex vivo gene... University Of Florida Research Foundation

Mems capacitive shear sensor system having an interface circuit

A sensor system comprising a Micro-Electro-Mechanical Systems (MEMS)-based capacitive floating element shear stress sensor, the associated packaging, and the interface circuitry required for operation as an instrumentation-grade sensing system is disclosed herein. One implementation of the interface circuitry is an analog synchronous modulation/demodulation scheme enabling time-resolved measurements of both mean... University Of Florida Research Foundation

Common-mask guided image reconstruction for enhanced four-dimensional cone-beam computed tomography

A system for constructing images representing a 4DCT sequence of an object from a plurality of projections taken from a plurality of angles with respect to the object and at a plurality of times, first portions of the object being less static than second portions of the object. The system... University Of Florida Research Foundation

Context-sensitive flow interrupter and drainage outflow optimization system

Embodiments of the invention provide methods and devices for improved drainage systems and tubing. In one embodiment, a context-sensitive flow interrupter is provided that inhibits or facilitates flow of fluid when engaged with a mating holder. In another embodiment, outflow is optimized through control of the pressure in gas pockets... University Of Florida Research Foundation

Recombinant aav production in mammalian cells

The present invention includes methods and compositions for the production of high titer recombinant Adeno-Associated Virus (rAAV) in a variety of mammalian cells. The disclosed rAAV are useful in gene therapy applications. Disclosed methods based on co-infection of cells with two or more replication-defective recombinant herpes virus (rHSV) vectors are... University Of Florida Research Foundation

Virtual barricade for radiation inspection of predefined paths

A method of operating a radiation inspection system includes identifying a regulatory region along a predetermined path where public access is restricted based upon criteria other than radiation exposure, measuring a radiation exposure level from a radiation source of the radiation inspection system within the regulatory region, irradiating a target... University Of Florida Research Foundation

Rotating radiation shutter collimator

A shutter for controlling radiation exposure includes a rotatable member. The rotatable member is rotatable between an open position and a closed position. The rotatable member includes a passageway, wherein the passageway is positioned to receive radiation in the open position and is not positioned to receive radiation in the... University Of Florida Research Foundation

Three-dimensional image reconstruction using transmission and scatter radiography methods

A method for image reconstruction includes irradiating an object with a beam of radiation from a radiation source, measuring an attenuated portion of the beam, estimating a density of the object, determining a predicted attenuated portion of the beam using the density estimate, and iteratively adjusting the density estimate of... University Of Florida Research Foundation

Nanocomposite magnetic materials for magnetic devices and systems

Nanocomposite magnetic materials, methods of manufacturing nanocomposite magnetic materials, and magnetic devices and systems using these nanocomposite magnetic materials are described. A nanocomposite magnetic material can be formed using an electro-infiltration process where nanomaterials (synthesized with tailored size, shape, magnetic properties, and surface chemistries) are infiltrated by electroplated magnetic metals... University Of Florida Research Foundation

High electron mobility transistors with improved heat dissipation

III-nitride based high electron mobility transistors (HEMTs), such as AlGaN/GaN HEMTs on Silicon substrates, with improved heat dissipation are described herein. A semiconductor device having improved heat dissipation may include a substrate having a top surface and a bottom surface, a nucleation layer on the top surface of the substrate,... University Of Florida Research Foundation

Interactive mixed reality system and uses thereof

An interactive mixed reality simulator is provided that includes a virtual 3D model of internal or hidden features of an object; a physical model or object being interacted with; and a tracked instrument used to interact with the physical object. The tracked instrument can be used to simulate or visualize... University Of Florida Research Foundation

Wireless power transfer via electrodynamic coupling

Wireless power transmission (WPT) systems are provided. According to an embodiment, the WPT system uses one or more power transmitting coils and a receiver for electromagnetically coupled wireless power transfer. The electrodynamic receiver can be in the form of an electrodynamic transducer where a magnet is allowed to oscillate near... University Of Florida Research Foundation

Protein biomarkers for acute, subacute and chronic traumatic injuries of the central nervous system

Proteins that are differentially expressed or elevated in tissue and biofluids after central nervous system injuries are described. Elevated or reduced levels of the proteins, alone or in various combinations or ratios, can be used to assess severity of central nervous system injury (CNS injury) including traumatic brain injury (TBI),... University Of Florida Research Foundation

Screening for neurological disease using speech articulation characteristics

Detection of neurological diseases such as Parkinson's disease can be accomplished through analyzing a subject's speech for acoustic measures based on human factor cepstral coefficients (HFCC). Upon receiving a speech sample from a subject, a signal analysis can be performed that includes identifying articulation range and articulation rate using HFCC... University Of Florida Research Foundation

Capacitive microphone with integrated cavity

A capacitive microphone and method of fabricating the same are provided. One or more holes can be formed in a first printed circuit board (PCB). A diaphragm can be surface micro-machined onto an interior surface of the first PCB at a region having the one or more holes. Interface electronics... University Of Florida Research Foundation

Macrocyclic therapeutic agents, methods of manufacture, and methods of treatment

The instant invention describes macrocyclic compounds having therapeutic activity, and the mechanism and methods of treating disorders such as autoimmune diseases, inflammation, and cancer, tumors and cell proliferation related disorders.... University Of Florida Research Foundation

Lipoteichoic acid from lactobacilli as a potent immune stimulatory adjuvant for vaccine development

The present invention provides compositions and methods useful for vaccination and generating CD8+ T lymphocyte immune memory against one or more antigens utilizing lipoteichoic acid.... University Of Florida Research Foundation

System and internal inspection of rail components

An internal imaging system has a radiation source and a plurality of detectors positioned to receive portions of the plurality of collimated beams that have been attenuated by interaction with the target. The radiation source is configured to irradiate a target with a plurality of collimated beams of radiation. Two... University Of Florida Research Foundation

Materials and methods for the treatment of latent viral infection

The subject invention pertains to materials and methods for the treatment of latent viral infections.... University Of Florida Research Foundation

Method of treating or retarding the development of blindness

A method for treating an ocular disorder characterized by the defect or absence of a normal gene in the ocular cells of a human or animal subject involves administering to the subject by subretinal injection an effective amount of a recombinant adeno-associated virus carrying a nucleic acid sequence encoding the... University Of Florida Research Foundation

 new patent  Aav vectors with high transduction efficiency and uses thereof for gene therapy

The present invention provides AAV capsid proteins comprising modification of one or a combination of the surface-exposed lysine, serine, threonine and/or tyrosine residues in the VP3 region. Also provided are rAAV virions comprising the AAV capsid proteins of the present invention, as well as nucleic acid molecules and rAAV vectors... University Of Florida Research Foundation

 new patent  Integrated miniature polarimeter and spectrograph using static optics

Embodiments provide an integrated miniature polarimeter and spectrograph (IMPS) and associated methods for using an IMPS to determine Stokes parameters to describe a source beam. In one embodiment an IMPs is provided comprising a spectropolarimeter module. The spectropolarimeter module comprises a miniature optical bench; a slit component; a birefringent wedge;... University Of Florida Research Foundation

Nickel titanium alloys, methods of manufacture thereof and article comprising the same

Disclosed herein is a shape memory alloy comprising 48 to 50 atomic percent nickel, 15 to 30 atomic percent hafnium, 1 to 5 atomic percent aluminum; with the remainder being titanium. Disclosed herein too is a method of manufacturing a shape memory alloy comprising mixing together to form an alloy... University Of Florida Research Foundation

Mixtures, articles having low coefficients of friction, methods of making these, and methods of using these

The present disclosure provides for mixtures, methods for making mixtures, articles, methods for making articles, and methods of using articles. In an aspect, the articles have superior tribological properties owing to combinations of polytetrafluoroethylene and an irradiated fluoropolymer described herein.... University Of Florida Research Foundation

03/22/18 / #20180078423

Bilayered devices for enhanced healing

Disclosed herein is a multilayered wound dressing comprising a first layer; the first layer including channels that facilitate neovascularization of a wound; and a second layer in contact with the first layer, the second layer having the same or different chemical composition as the first layer; where the second layer... University Of Florida Research Foundation

03/08/18 / #20180064760

Methods for treating or preventing graft versus host disease

A method of treating or preventing graft versus host disease (GVHD) in a subject receiving a graft comprising hematopoietic cells is provided. The method comprises contacting the graft ex vivo with an amount of a Myxoma Virus effective to inhibit proliferation of T lymphocytes in the graft and to treat... University Of Florida Research Foundation

03/08/18 / #20180067291

Telescope and telescope array for use in spacecraft

A catadioptric telescope is a modified version of a conventional Maksutov-Cassegrain optical telescope. In accordance with the invention, the reflecting surfaces of the primary mirror and the secondary spot mirror are on the second surfaces of the primary mirror and correcting lens, respectively. In further accordance with the invention, two... University Of Florida Research Foundation

03/01/18 / #20180057840

Raav vector compositions, methods for targeting vascular endothelial cells and use in treatment of type i diabetes

Disclosed are capsid-modified rAAV expression vectors, as well as infectious virions, compositions, and pharmaceutical formulations that include them. Also disclosed are methods of preparing and using novel capsid-protein-mutated rAAV vector constructs in a variety of diagnostic and therapeutic applications including, inter alia, as delivery agents for diagnosis, treatment, or amelioration... University Of Florida Research Foundation

03/01/18 / #20180059123

Neural proteins as biomarkers for nervous system injury and other neural disorders

The present invention identifies biomarkers that are diagnostic of nerve cell injury and/or neuronal disorders. Detection of different biomarkers of the invention are also diagnostic of the degree of severity of nerve injury, the cell(s) involved in the injury, and the subcellular localization of the injury.... University Of Florida Research Foundation

02/22/18 / #20180049654

Devices, plethysmographic monitoring at the nose

The present invention relates to novel lip/cheek probes for detection of pulse-based differences in light absorbence across the vascularized tissue of a lip or cheek of a patient. These probes are fabricated to provide signals to estimate arterial oxygen saturation, and/or to obtain other photoplethysmographic data. The present invention also... University Of Florida Research Foundation

02/22/18 / #20180051279

Methods of identifying biologically active random peptides in plants and libraries of plants expressing candidate biologically active random peptides

The present disclosure provides methods and systems for identifying biologically active random peptides (BARPs) in plants. The present disclosure also provides libraries of transformed plants, where each plant expresses a different candidate BARP. Also provided are engineered, isolated BARPs capable of producing a non-wild type phenotype in plants.... University Of Florida Research Foundation

02/22/18 / #20180051299

Compositions and methods for treating diseases

... University Of Florida Research Foundation

02/15/18 / #20180044379

Co-assembly peptides, nanostructures, and methods of making and using the same

Provided herein are charge complementary peptides that can be optionally coupled to a cargo polypeptide that are capable of self-assembling under stimulating conditions. The charge complementary peptides can be capable of forming supramolecular structures. Also provided herein are methods of using the charge complementary peptides provided herein.... University Of Florida Research Foundation

02/08/18 / #20180036385

Aav-mediated gene therapy for rpgr x-linked retinal degeneration

Described herein are methods of preventing, arresting progression of or ameliorating vision loss and other conditions associated with retinitis pigmentosa and x-linked retinitis pigmentosa in a subject. The methods include administering to said subject an effective concentration of a composition comprising a recombinant adeno-associated virus (AAV) carrying a nucleic acid... University Of Florida Research Foundation

02/08/18 / #20180037466

Method for the generation of power

Disclosed herein is a method comprising heating a strontium-containing compound using radiation in a first reactor; decomposing the strontium-containing compound into an oxide and carbon dioxide as a result of heat generated by the exposure to the radiation; reacting the oxide and the carbon dioxide in a second reactor; where... University Of Florida Research Foundation

02/08/18 / #20180038873

Use of nhe3 as a biomarker for radiation biodosimetry

Embodiments of the present invention are directed to the use of NHE3 as an early biomarker for radiation biodosimetry. In other embodiments, the present invention relates to the use of NHE3 as a biomarker for determining the absorbed radiation dose in a subject who has been exposed to a known... University Of Florida Research Foundation

02/01/18 / #20180027804

Particle based enhanced removal for disinfection of surfaces

A suspension for removing microbes from a surface comprises contacting a plurality of modified particles (MPs), comprise a plurality of microparticles are coated by one or more polymers or their surfaces are covalently bonded to functionality that promotes a cationic surface. The microparticles can be a metal, metal oxide, an... University Of Florida Research Foundation

02/01/18 / #20180030096

Recombinant aav1, aav5, and aav6 capsid mutants and uses thereof

Provided herein are modified recombinant adeno-associated virus (rAAV) capsid proteins, such as modified rAAV1, rAAV5, and rAAV6 capsid proteins, rAAV particles comprising such capsid proteins, nucleic acid molecules encoding such capsid proteins, as well as compositions, kits and methods of use thereof.... University Of Florida Research Foundation

02/01/18 / #20180030209

Mesh size control of lubrication in gemini hydrogels

A device comprises a surface that is a hydrogel having a targeted mesh size that permits a low-speed friction coefficient near or lower that that typically reported for cartilage of 0.01 to 0.02, a transition. The device can be a contact lens to sit on the cornea where, during a... University Of Florida Research Foundation

02/01/18 / #20180030461

Citrus tristeza virus based vectors for foreign gene/s expression

... University Of Florida Research Foundation

02/01/18 / #20180033511

Optoelectronic nuclear batteries based on radionuclide nanoencapsulation and organic photodiodes

Embodiments of the present disclosure relate to compositions including a doped material, batteries including the composition, photovoltaic devices including the battery, and the like.... University Of Florida Research Foundation

01/25/18 / #20180020663

Conjugated polyelectrolytes and methods of using the same

Various embodiments disclosed relate to conjugated polyelectrolytes and methods of using the same. Various embodiments provide a conjugated polyelectrolyte including a subunit having the structure —R1—Y—R2—Z—. At each occurrence, R1 is independently chosen from 1,4-bonded phenylene substituted by —X—R3—R4 j times and 2,5-bonded thiophene substituted by —X—R3—R4 j times. At... University Of Florida Research Foundation

01/25/18 / #20180021140

High speed 3d printing system for wound and tissue replacement

A method or apparatus for creating a three-dimensional tissue construct of a desired shape for repair or replacement of a portion of an organism. The method may comprise injecting at least one biomaterial in a three-dimensional pattern into a first material such that the at least one biomaterial is held... University Of Florida Research Foundation

01/25/18 / #20180022815

Bi-specific chimeric antigen receptor and uses thereof

Provided herein are bi-specific chimeric antigen receptors (CARs), such as those specific for CD138 and BCMA. Use of the CARs in immune cells (e.g., T cells), compositions, and methods are also contemplated.... University Of Florida Research Foundation

01/25/18 / #20180026259

Mixed redox couple electrodes for rate capability and overdischarge protection

A composite electrode is a composite of conductive materials of at least a first material and a second material, wherein the first material undergoes a parasitic reaction in a region where the second material is stable, and the first material and second material are stable at the first material's nominal... University Of Florida Research Foundation

01/18/18 / #20180015172

Engineered receptor/ligand system for delivery of therapeutic agents

Provided herein are compositions and methods related to targeted delivery of a therapeutic or diagnostic agent to a subject utilizing an engineered receptor-ligand system, such as an engineered dockerin-cohesin system. As described herein, previously-developed targeted delivery systems for delivering therapeutic and diagnostic agents to a tissue of interest have drawbacks... University Of Florida Research Foundation

01/18/18 / #20180017569

Medication adherence monitoring system

The present invention relates to the detection of markers in exhaled breath, wherein the detection of the presence or absence of the marker(s) in exhaled breath is used to assess various clinical data, including patient adherence in taking the medication and patient enzymatic (metabolic) competence in metabolizing the medication. An... University Of Florida Research Foundation

01/18/18 / #20180019491

Hydrogen oxidation and generation over carbon films

An electrode comprises an acid treated, cathodically cycled carbon-comprising film or body. The carbon consists of single walled nanotubes (SWNTs), pyrolytic graphite, microcrystalline graphitic, any carbon that consists of more than 99% sp2 hybridized carbons, or any combination thereof. The electrode can be used in an electrochemical device functioning as... University Of Florida Research Foundation

01/11/18 / #20180008155

Methods and devices for central photoplethysmographic monitoring

Provided according to embodiments of the present invention are methods of monitoring individuals that include securing a photoplethysmography probe to at least one of a pre-auricular region and a post-auricular region of the individual and obtaining photoplethysmography signals from the photoplethysmography probe. Photoplethysmography probes and helmets related to such methods... University Of Florida Research Foundation

01/11/18 / #20180008328

Articles comprising reversibly attached screws comprising a biodegradable composition, methods of manufacture thereof and uses thereof

Disclosed herein is an article comprising a first screw and a second screw, the first screw being reversibly attached to the second screw such that a longitudinal axis of the first screw coincides with or is parallel to a longitudinal axis of the second screw; the first screw and the... University Of Florida Research Foundation

01/11/18 / #20180008737

Self-sterilizing device using plasma fields

Embodiments of the invention relate to a method and apparatus for self-sterilizing a surface or other portion of the apparatus and/or sterilizing other objects. Embodiments can utilize self-generated and/or remotely controlled plasma fields for the purpose of self-sterilization and/or sterilization of another object. Embodiments of the invention can have broad... University Of Florida Research Foundation

01/04/18 / #20180007772

Devices employing one or more plasma actuators

Various embodiments relate to plasma actuators that generate fluidic flow. In one or more embodiments, a plasma actuator includes a first electrode and a second electrode. A dielectric film physically separates the first electrode and the second electrode of the plasma actuator. The dielectric film is configured to be attached... University Of Florida Research Foundation

12/28/17 / #20170367976

Pharmaceutical capsules for medication adherence monitoring and methods of forming the same

Provided according to embodiments of the invention pharmaceutical capsules that include a capsule body and a capsule cap, wherein the capsule cap envelops an open end of the capsule body to form a capsule core; and an adherence sheath that envelops a portion of the capsule core. Related capsules and... University Of Florida Research Foundation

12/28/17 / #20170370050

Waste to energy ash and engineered aggregate in road construction

Described herein are compositions and methods for waste-to-energy ash in engineered aggregate in road construction.... University Of Florida Research Foundation

Patent Packs
12/28/17 / #20170372640

Simulation features combining mixed reality and modular tracking

Techniques and systems are described for providing modularity, tracking and simulation features of a mixed reality simulator. A modular approach to tracking systems, tracked instruments, and interchangeable modular physical models is described. Enhanced indicators and indicator interfaces improve imaging probe and instrument orientation and alignment with respect to a physical... University Of Florida Research Foundation

12/21/17 / #20170361534

3d printing using phase changing materials as support

A method or apparatus for three-dimensionally printing. The method may comprise causing a phase change in a region of the first material by applying focused energy to the region using a focused energy source, and displacing the first material with a second material. The apparatus may comprise a container configured... University Of Florida Research Foundation

12/14/17 / #20170356009

Genome-modified recombinant adeno-associated virus vectors

Provided herein are recombinant adeno-associated virus (rAAV) nucleic acid vectors that comprise one or more modifications within at least one inverted terminal repeat (ITR) region. Exemplary modifications include ITR sequences comprising a glucocorticoid responsive element and/or a transcription factor binding site. Also provided are plasmids, libraries, rAAV particles, compositions, kits,... University Of Florida Research Foundation

12/07/17 / #20170347602

Oat variety fl0720

The invention provides oat seed and plants of the oat variety FL0720 that have resistance to crown rust. The invention further provides seed and plants of the oat variety FL0720 and progeny produced with at least one of these plants as a parent. The invention also relates to the plants,... University Of Florida Research Foundation

12/07/17 / #20170348387

Aav-mediated gene therapy for nphp5 lca-ciliopathy

Described herein are methods of preventing, arresting progression of or ameliorating vision loss and other conditions associated with Leber congenital amaurosis (LCA) in a subject. The methods include administering to said subject an effective concentration of a composition comprising a recombinant adeno-associated virus (AAV) carrying a nucleic acid sequence encoding... University Of Florida Research Foundation

11/23/17 / #20170333628

Devices and methods for minimizing infusion of air into an intravenous fluid line from an intravenous fluid bag by a pressure infusion cuff

The problem of infusing air into IV tubing and into a patient from a IV fluid bag inside a pressure infusion cuff is solved by collar embodiments that inhibit the air from being forced into the IV tubing. A collar can include one or more curved arms that create a... University Of Florida Research Foundation

11/16/17 / #20170326257

Satiation peptides for weight loss and altered taste sensitivity

The present application provides methods and compositions for AAV-mediated delivery of PYY and Glucagon-like Peptide 1 or an analog thereof (e.g., Exendin-4) to a subject (e.g., the saliva of a subject). In some embodiments, compositions and methods for topical delivery of Ex-4 and PYY peptides also are provided. Methods and... University Of Florida Research Foundation

11/16/17 / #20170327875

Sensitive and rapid candidatus liberibacter species detection

DNA amplification methods using novel primers obtained from the novel genes hyvI and hyvII from the Candidatus Liberibacter asiaticus genome are useful for detecting Ca. L. species in plants and insect hosts.... University Of Florida Research Foundation

11/09/17 / #20170320018

Continuous electrokinetic dewatering of phosphatic clay suspensions

Various methods and systems are provided for electrokinetic dewatering of suspensions such as, e.g., phosphatic clay. In one example, among others, a system for continuous dewatering includes a cake formation zone including a first anode and a first cathode each extending across a first portion of a separation chamber; a... University Of Florida Research Foundation

11/09/17 / #20170321306

Radiation shielding and mitigating alloys, methods of manufacture thereof and articles comprising the same

Embodiments of the present disclosure include compositions that include magnesium and gadolinium or magnesium and one or more metals.... University Of Florida Research Foundation

11/02/17 / #20170317678

Overlay architecture for programming fpgas

An overlay architecture and an associated method that uses datapath merging to provide minimal-overhead support for multiple source netlists, and optionally provides an adjustable amount of flexibility through a secondary interconnect network is disclosed.... University Of Florida Research Foundation

11/02/17 / #20170317678

Overlay architecture for programming fpgas

An overlay architecture and an associated method that uses datapath merging to provide minimal-overhead support for multiple source netlists, and optionally provides an adjustable amount of flexibility through a secondary interconnect network is disclosed.... University Of Florida Research Foundation

10/26/17 / #20170304794

Solar thermochemical reactor and methods of manufacture and use thereof

Disclosed herein is a solar reactor comprising a reactor member; an aperture for receiving solar radiation, the aperture being disposed in a plane on a wall of the reactor member, where the plane is oriented at any angle other than parallel relative to the centerline of the reactor member; a... University Of Florida Research Foundation

10/26/17 / #20170304797

Solar thermochemical reactor, methods of manufacture and use thereof and thermogravimeter

Disclosed herein is a solar thermochemical reactor comprising an outer member, an inner member disposed within an outer member, wherein the outer member surrounds the inner member and wherein the outer member has an aperture for receiving solar radiation and wherein an inner cavity and an outer cavity are formed... University Of Florida Research Foundation

10/26/17 / #20170306368

Methods for thaxtomin production and modified streptomyces with increased thaxtomin production

In accordance with the purpose(s) of the present disclosure, as embodied and broadly described herein, embodiments of the present disclosure, in some aspects, relate to genetically modified Streptomyces bacteria capable of increased thaxtomin production, genetically modified Streptomyces bacteria with reduced activity of a CebR protein encoded by a cebR gene... University Of Florida Research Foundation

Patent Packs
10/19/17 / #20170297058

Methods and structures for light regulating coatings

The present disclosure describes various embodiments of a structure for a composite light regulating film, methods of using the composite light regulating film, and for methods of making a composite light regulating film.... University Of Florida Research Foundation

10/19/17 / #20170298370

Viral based transient-expression vector system that allows multiple applications

Disclosed herein are viral vectors suitable for transfection into woody trees for purposes of delivering and expressing beneficial genes. Specifically exemplified herein are vectors for transfecting citrus trees. The vectors allow for the expression of useful proteins, such as those that can protect the tree from disease. Specifically exemplified herein... University Of Florida Research Foundation

10/05/17 / #20170283854

Multiplexed pcr assay for high throughput genotyping

The present invention relates to identification and characterization of polymorphisms in a nucleic acid sample. Methods and compositions for the unbiased amplification of multiple target sequences within a nucleic acid sample are provided.... University Of Florida Research Foundation

10/05/17 / #20170284429

Electro-fluid transducers

The present disclosure is directed towards electro-fluid transducers that may influence the flow of a fluid in and around a channel. In one such embodiment, a system comprises a first electrode at least partially encapsulated by a first dielectric; a second electrode at least partially encapsulated by a second dielectric,... University Of Florida Research Foundation

09/28/17 / #20170275178

Room temperature multiferroic thin films

Various examples are provided for multiferroic thin films. In one example, a multiferroic thin film device includes a thin film of multiferroic material and an electrode disposed on a side of the thin film of multiferroic material. The multiferroic material can be (Fex,Sr1-x)TiO3 In another example, a method for producing... University Of Florida Research Foundation

09/28/17 / #20170275337

High-transduction-efficiency raav vectors, compositions, and methods of use

The present invention provides AAV capsid proteins comprising modification of one or a combination of the surface-exposed lysine, serine, threonine and/or tyrosine residues in the VP3 region. Also provided are rAAV virions comprising the AAV capsid proteins of the present invention, as well as nucleic acid molecules and rAAV vectors... University Of Florida Research Foundation

09/21/17 / #20170267576

Durable and optically transparent superhydrophobic surfaces

Durable and optically transparent superhydrophobic surfaces have a coating of ceramic nanoparticles attached to a transparent substrate that are bound to the substrate through a flexible linker and a fluorocarbon moiety is bound to the surface of the ceramic nanoparticles. The nanoparticles provide the topography required for superhydrophobic surfaces and... University Of Florida Research Foundation

09/21/17 / #20170267700

Precursors for electron beam-induced deposition of gold and silver

Precursors are prepared and employed in electron beam induced decomposition (EBID). The EBID precursors are complexes of the formula: X-M-Y, where M is Au or Ag; X is F, Cl, Br, I, CN, OR1, O2CR2, or R3; Y is P(OR)3, NR3, unsubstituted or substituted pyrrole, unsubstituted or substituted pyridine, unsubstituted... University Of Florida Research Foundation

09/21/17 / #20170267811

Broadly absorbing electrochromic polymers

Copolymers including dioxythiophene repeating units and no acceptor units allow the formation of electrochromic polymers (ECPs) with vivid neutral state colors and very colorless oxidized states that can be switched rapidly. The dioxythiophene repeating units can included in sequences where all of one type of dioxythiophene is included exclusively as... University Of Florida Research Foundation

09/21/17 / #20170268019

Methods and compositions for preventing or reducing infections of crop plants by bacterial and fungal pathogens

The present invention teaches methods and compositions useful for treating, preventing, or curing pathogen infections of living plants. In particular, the present invention teaches methods of enhancing plant response to pathogen-associated molecular patterns. The methods and compositions described herein are effective at treating biotrophic pathogens, including Liberibacters.... University Of Florida Research Foundation

09/14/17 / #20170260403

Durable and superhydrophobic over coating

An overcoat that imparts a superhydrophobic surface to a painted surface of an object is a suspension of hydrophobic particles in a polymeric binder and a plasticizer in a solvent or mixed solvent. The particles are a metal oxide that is surface functionalized with a fluorinated alkyl silane or an... University Of Florida Research Foundation

08/31/17 / #20170245495

Chemical lure for asian citrus psyllid

The present disclosure relates to compositions containing a mixture of e.g. one or more or two or more compounds released by a citrus plant in quantities that are altered during infection with Huanglongbing disease, where the composition is an attractant for psyllids. Furthermore, compositions contain one or more active compounds... University Of Florida Research Foundation

08/24/17 / #20170238871

Novel pulse oximeter probes and methods for using the same

Provided according to embodiments of the invention are photoplethysmography probes designed for use on a user's nasal alar. Methods of using such photoplethysmography probes are also provided herein.... University Of Florida Research Foundation

08/24/17 / #20170239393

Magnetic nanoparticle embedded nanofibrous membrane

Various examples are provided for magnetic particle imbedded nanofibrous membranes. In one example, among others, a nanofibrous membrane includes one or more electrospun nanofibers forming form a layer of nanofibers, and a plurality of magnetic nanoparticles embedded in the one or more electrospun nanofibers. In another example, a method includes... University Of Florida Research Foundation

08/17/17 / #20170233754

Materials and methods to increase plant growth and yield

The present invention relates to materials and methods for modulating growth rates, yield, and/or resistance to drought conditions in plants. In one embodiment, a method of the invention comprises increasing expression of an hc1 gene (or a homolog thereof that provides for substantially the same activity), or increasing expression or... University Of Florida Research Foundation

08/10/17 / #20170224531

Preservative removal from eye drops

A BAK removal device is constructed as a plug of microparticles of a hydrophilic polymeric gel that displays a hydraulic permeability greater than 0.01 Da. The polymer hydrophilic polymeric gel comprises poly(2-hydroxyethyl methacrylate) (pHEMA). The particles are 2 to 100 μm and the plug has a surface area of 30... University Of Florida Research Foundation

08/10/17 / #20170230144

Joint fountain coding and network coding for loss-tolerant information spreading

A network system for increasing data throughput and decreasing transmission delay from a source node to a sink node via a relay node. The network system may comprise a source node configured to encode a plurality of data packets using rateless coding and transmit the plurality of data packets; at... University Of Florida Research Foundation

08/03/17 / #20170216543

Patterns for flow control and bioadhesion control

Disclosed herein is an article including a path that extends across at least a portion of a surface of the article, the path being defined by at least one channel that traverses at least a portion of the surface or a first plurality of spaced features disposed on or in... University Of Florida Research Foundation

08/03/17 / #20170217771

Solar thermochemical reactor, methods of manufacture and use thereof and thermogravimeter

Disclosed herein is a solar thermochemical reactor comprising an outer member, an inner member disposed within an outer member, wherein the outer member surrounds the inner member and wherein the outer member has an aperture for receiving solar radiation and wherein an inner cavity and an outer cavity are formed... University Of Florida Research Foundation

08/03/17 / #20170217912

Desferrithiocin polyether analogues

or a pharmaceutically acceptable salt thereof are useful in treating conditions such as metal overload, oxidative stress, and neoplastic and preneoplastic conditions.... University Of Florida Research Foundation

08/03/17 / #20170217984

Ligands for alpha-7 nicotinic acetylcholine receptors and methods of treating neurological and inflammatory conditions

Compounds are provided which bind to an allosteric site on the mammalian alpha-7 nicotinic acetylcholine receptor (alpha-7 nAChR) and act as positive allosteric modulators with or without allosteric agonist activity. The compounds are useful in diagnosing, preventing, or treating a variety of disorders involving cognition, learning, memory, neurodegeneration, drug addiction,... University Of Florida Research Foundation

08/03/17 / #20170218395

Methods of packaging multiple adeno-associated virus vectors

Provided herein are methods related to co-packaging of multiple rAAV particles, e.g., by introducing multiple nucleic acid vectors encoding proteins or polypeptides or RNAs of interest into a single cell preparation.... University Of Florida Research Foundation








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