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University Of Georgia Research Foundation Inc
University Of Georgia Research Foundation Inc Boyd Graduate Studies Research Center

University Of Georgia Research Foundation Inc patents


Recent patent applications related to University Of Georgia Research Foundation Inc. University Of Georgia Research Foundation Inc is listed as an Agent/Assignee. Note: University Of Georgia Research Foundation Inc may have other listings under different names/spellings. We're not affiliated with University Of Georgia Research Foundation Inc, we're just tracking patents.

ARCHIVE: New 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 | Company Directory "U" | University Of Georgia Research Foundation Inc-related inventors


Platinum prodrugs and methods of making and using thereof

Disclosed herein are prodrugs of platinum containing anticancer agents such as cisplatin that contain an alkylating moiety. Upon administration, the prodrugs release the platinum containing anticancer agent and the alkylating agent, which can form an adduct with DNA or can protect the platinum containing agent from removal. The disclosed prodrugs... University Of Georgia Research Foundation Inc

Piv5-based amplifying virus-like particles

Compositions, methods of use and methods of manufacture are provided for PIV5-based amplifying VLP (AVLP) that can deliver an expressible heterologous nucleotide sequence in target cells without producing progeny, and which demonstrate useful safety and therapeutic efficacy in multiple animal and human health applications, such as vaccination, gene therapy and... University Of Georgia Research Foundation Inc

Continuous and rapid quantification of stroke volume from magnetohydrodynamic voltages in magnetic resonance imaging

Described here are systems and methods for providing a non-invasive and continuous quantitative measurement of left ventricular stroke volume (“SV”) and flow volume during a magnetic resonance imaging (“MRI”) scan. In general, the method estimates quantitative measurements of SV from magnetohydrodynamic (“MHD”] voltages generated by blood flowing through the subject's... University Of Georgia Research Foundation Inc

Chimeric enzymes for conversion of lignin-derived chemicals

Disclosed herein are enzymes useful for the dealkylation of aromatic substrates, including the conversion of guaiacol or guaethol to catechol. Methods of converting aromatic substrates found in lignin-based feedstocks such as pyrolysis oil into products such as catechol are also disclosed. Also presented herein are methods for rapidly evolving and... University Of Georgia Research Foundation Inc

Ultra high-speed photonics based radio frequency switching

Various examples are provided for radio frequency (RF) switching. In one example, a RF switch includes a dual-drive Mach-Zehnder modulator (DDMZM) that can generate a single-sideband (SSB) signal by modulating an input RF signal onto an optical carrier; a tunable phase modulator incorporated loop mirror filter (PM-LMF) that can optically... University Of Georgia Research Foundation Inc

Pecan tree named 'tanner'

... University Of Georgia Research Foundation Inc

Photochemical cross-linkable polymers, methods of making photochemical cross-linkable polymers, methods of using photochemical cross-linkable polymers, and methods of making articles containing photochemical cross-linkable polymers

Embodiments of the present disclosure, in one aspect, relate to structures having a polymer composition covalently bonded to the surface of the structure, methods of attaching the polymer to the surface of the structure, methods of decreasing the amount of microorganisms formed on a structure, materials, methods of attaching materials,... University Of Georgia Research Foundation Inc

Nanoparticles for lipid homeostasis

Nanoparticles include a polymeric core and a high density lipoprotein (HDL) component where the ratio by weight of the HDL component to the polymeric core is in a range from about 1:9 to about 9:1, such as about 75:25 or less or about 7:3 or less. The nanoparticles may also... University Of Georgia Research Foundation Inc

Use of xanthophyll carotenoids to improve visual performance and neural efficiency

In one embodiment, the invention provides a method of enhancing a subject's macular pigment optical density, the method comprising administering to the subject a pharmaceutically effective amount of one or more Xanthophyll carotenoids. Preferably, the Xanthophyll carotenoids are selected from the group consisting of lutein (L), zeaxanthin (Z), and meso-zeaxanthin... University Of Georgia Research Foundation Inc

Piv5 as an oncolytic agent

The present invention includes the Paramyxovirus Parainfluenza Virus 5 (PIV5) as an oncolytic agent for treating various cancers, including, but not limited to breast cancer, lung cancer and melanoma. PIV5 oncolytic agents include both wild type PIV5 and various recombinant PIV5 constructs. Recombinant PIV5 constructs may include PIV5 lacking the... University Of Georgia Research Foundation Inc

Alkynes and methods of reacting alkynes with 1,3-dipole-functional compounds

1,3-Dipole-functional compounds (e.g., azide functional compounds) can be reacted with certain alkynes in a cyclization reaction to form heterocyclic compounds. Useful alkynes (e.g., strained, cyclic alkynes) and methods of making such alkynes are also disclosed. The reaction of 1,3-dipole-functional compounds with alkynes can be used for a wide variety of... University Of Georgia Research Foundation Inc

Systems and methods for measuring mitochondrial capacity

In one embodiment, measuring mitochondrial capacity includes performing arterial occlusions on a patient, measuring oxygenated hemoglobin/myoglobin and deoxygenated hemoglobin/myoglobin within the patient's body during the occlusions, calculating a blood volume correction factor that accounts for a change in blood volume that occurs during the arterial occlusions, and applying the correction... University Of Georgia Research Foundation Inc

Microbial approach for the production of 5-hydroxytryptophan

5-hydroxytryptophan (5-HTP), a precursor of serotonin, is produced in a microbial host cell. A modified bacterial phenylalanine 4-hydroxylase (P4H) catalyzes the tryptophan 5-hydroxylation reaction. Optionally the host cell includes a cofactor regeneration mechanism, allowing continuous production of 5-HTP without supplementation of exogenous cofactors.... University Of Georgia Research Foundation Inc

Recombinant mumps virus vaccine

The present invention provides the complete genomic sequence of the epidemic mumps virus (MuV) strain MuVIowa/US/06. Further, a reverse genetics system was constructed and used to rescue recombinant viral constructs that are attenuated compared to rMuVIowa/US/06 and JL vaccine viruses. Such constructs include viral constructs lacking the open reading frame... University Of Georgia Research Foundation Inc

Sequestration of carbon dioxide with hydrogen to useful products

Provided herein are genetically engineered microbes that include at least a portion of a carbon fixation pathway, and in one embodiment, use molecular hydrogen to drive carbon dioxide fixation. In one embodiment, the genetically engineered microbe is modified to convert acetyl CoA, molecular hydrogen, and carbon dioxide to 3-hydroxypropionate, 4-hydroxybutyrate,... University Of Georgia Research Foundation Inc

Therapeutic nanoparticles for accumulation in the brain

Nanoparticles containing a mitochondrial that are capable of crossing the blood-brain barrier and that have a targeting moiety, an antioxidant and an anti-inflammatory agent may be useful for treatment of traumatic brain injury.... University Of Georgia Research Foundation Inc

Metal-encapsulated carbonaceous dots

Nanoparticles described as metal-encapsulated carbonaceous dots or M@C-dots are disclosed. Also disclosed are specific M@C-dots with gadolinium, so called Gd@C-dots. These nanoparticles are biologically inert and preclude the release of metal in biological environments. In addition, despite a dimension exceeding the commonly recognized threshold for renal clearance, the disclosed nanoparticles... University Of Georgia Research Foundation Inc

Dwarf hybrid blueberry plant named 'to-1319'

... University Of Georgia Research Foundation Inc

Induced photodynamic therapy using nanoparticle scintillators as transducers

Photodynamic therapy systems comprising a nanoparticle that emits electromagnetic radiation having a first wavelength when irradiated with electromagnetic radiation, a photosensitizer which absorbs electromagnetic radiation of said first wavelength and a biocompatible mesoporous material are disclosed herein. In some examples, the photodynamic therapy system comprises a core comprising the nanoparticle,... University Of Georgia Research Foundation Inc

Vaccine delivery method

The present invention includes a composition including as one component a slurry matrix that is a liquid at room temperature and a gel at physiological pH, physiological salt concentrations and/or physiological temperatures and as a second component one or more antigens. Also include are methods of inducing an immune response... University Of Georgia Research Foundation Inc

Prodrug for release of cisplatin and cyclooxygenase inhibitor

... University Of Georgia Research Foundation Inc

Adenosine-specific rnase and methods of use

Provided herein are proteins having A-specific RNase activity. A protein having A-specific RNAse activity is referred to herein as a Csx1 protein. A Csx1 protein is an endoribonuclease, and has the activity of cleaving the phosphodiester bond in a single strand of a target RNA molecule on the 3′ (downstream)... University Of Georgia Research Foundation Inc

Carbohydrate-binding protein

The carbohydrate processing enzyme PNGase F was catalytically inactivated through mutation. Additional mutations yielded a catalytically inactive carbohydrate-binding protein with lectin-like properties including high affinity and specificity N-linked glycans, O-linked glycans, or both.... University Of Georgia Research Foundation Inc

Systems and methods for estimating and removing magnetic resonance imaging gradient field-induced voltages from electrophysiology signals

Systems and methods for estimating time-dependent voltages that are induced in electrophysiological monitoring systems by magnetic field gradients generated during a magnetic resonance imaging (“MRI”) scan are provided. The gradient-induced voltages are subsequently removed from signals acquired with the electrophysiological monitoring system during an MRI scan. As an example, the... University Of Georgia Research Foundation Inc

Exercise performance enhancers

Disclosed are compositions, articles, and method for enhancing exercise performance in a subject. The method involves contacting the oral cavity of the subject with a composition comprising a sweet and caloric food product for a period sufficient to cause a cephalic phase response in the subject.... University Of Georgia Research Foundation Inc

Site-specific antibody-drug glycoconjugates and methods

Compounds, compositions, and methods are provided for covalently linking an antibody or an antibody fragment to a cargo molecule, such as a therapeutic or a diagnostic agent, using a combination of enzymatic glycan remodeling and click chemistry. The method allows a cargo molecule to be selectively and efficiently attached post-translationally... University Of Georgia Research Foundation Inc

Cell lines for virus production and methods of use

... University Of Georgia Research Foundation Inc

Gd-encapsulated carbon dots and methods of making and using thereof

Gd-encapsulated carbonaceous dots (Gd@C-dots) hold great potential in clinical translation as Ti contrast agent for magnetic resonance imaging. However, current synthetic techniques yield particles with poor size control; hence, time-consuming size selection is often needed to obtain particles of desired sizes. Disclosed is a process whereby mesoporous silica nanoparticles are... University Of Georgia Research Foundation Inc

Microbial production of muconic acid and salicylic acid

The invention provides a recombinant microorganism that has been genetically engineered to contain metabolic pathway for the production of muconic acid from a salicylic acid intermediate. The genetically engineered metabolic pathway comprises both biosynthetic and biodegradative elements.... University Of Georgia Research Foundation Inc

Photochemical cross-linkable polymers, methods of making photochemical cross-linkable polymers, methods of using photochemical cross-linkable polymers, and methods of making articles containing photochemical cross-linkable polymers

Structures having a polymer composition covalently bonded to the surface of the structure, methods of attaching the polymer to the surface of the structure, methods of decreasing the amount of microorganisms formed on a structure, and the like, are disclosed.... University Of Georgia Research Foundation Inc

Photonic implementation of jamming avoidance response

Various examples are provided for jamming avoidance response (JAR), and photonic implementations thereof. In one example, a method includes generating optical pulses that correspond to raising envelope of a beat signal associated with an interference signal and a reference signal; generating optical spikes that correspond to positive zero crossing points... University Of Georgia Research Foundation Inc

Transgenic plants having altered expression of a xylan xylosyltransferase and methods of using same

Provided herein are plants having altered expression of an IRX10 or an IRX10-L protein. Such plants have phenotypes that may include decreased recalcitrance, increased growth, decreased lignin content, or a combination thereof. Also provided herein are methods of making and using such plants.... University Of Georgia Research Foundation Inc

Platinum(iv) compounds and methods of making and using same

Reactions of 1,3-dipole-functional (e.g., azide-functional) platinum(IV) compounds with cyclic alkynes under conditions effective for a cycloaddition reaction to form a heterocyclic compound are disclosed herein. In certain embodiments, the conditions effective for the cycloaddition reaction to form the heterocyclic compound includes the substantial absence of added catalyst (e.g., copper catalyst).... University Of Georgia Research Foundation Inc

Modification of drugs for incorporation into nanoparticles

Aspirin is chemically modified to generate a prodrug that releases aspirin in cellular milieu. The prodrug has a lipophilic tail that may enhance uptake efficiency in nanoparticles. Nanoparticles including the prodrugs may be effective for treating inflammatory disorders, including neurodegenerative disorders.... University Of Georgia Research Foundation Inc

03/23/17 / #20170086342

Dwarf hybrid blueberry plant named 'to-1088'

... University Of Georgia Research Foundation Inc

03/23/17 / #20170086343

Rabbiteye blueberry plant named 't-1101'

... University Of Georgia Research Foundation Inc

03/23/17 / #20170086344

Rabbiteye blueberry plant named 't-460'

... University Of Georgia Research Foundation Inc

03/16/17 / #20170072405

Devices and methods for separating particles

Embodiments of the present disclosure provide for devices, methods for separating particles, and the like.... University Of Georgia Research Foundation Inc

03/16/17 / #20170076622

Modular system for the real time assessment of critical thinking skills

Disclosed are various embodiments for assisting students in a development of critical thinking skills pertinent to solving problems. An educational system may access predefined education modules from memory that facilitate an interaction between a student and a user interface. The user input provided by the student is measured in real-time... University Of Georgia Research Foundation Inc

03/09/17 / #20170067080

Parainfluenza virus 5 based vaccines

The present invention provides safe, stable, efficacious, and cost-effective vaccines based on viral expression vectors that include a parainfluenza virus 5 (PIV5) genome including a heterologous nucleotide sequence expressing a heterologous polypeptide.... University Of Georgia Research Foundation Inc

02/09/17 / #20170037071

Mitochondria-targeting platinum(iv) prodrug

Pt(IV) compounds include a mitochondria targeting moiety. One example of a Pt(IV) compound having a mitochondria targeting moiety is a Pt(IV) cisplatin-based compound. Upon reduction, the mitochondrial targeting moieties are released resulting in a Pt(II) therapeutic agent. Pt(IV) compounds including a mitochondria targeting moiety can be included in nanoparticles. The... University Of Georgia Research Foundation Inc

02/02/17 / #20170028055

Avian reovirus vaccines

The present invention relates to novel strains of avian reovirus that were isolated from clinical cases of viral arthritis/tenosynovitis in chickens in the southeast United States. The invention is directed to these novel group 1 and group 2 avian reoviruses, diagnostic assays using antibodies and/or nucleotide- or amino acid-specific components... University Of Georgia Research Foundation Inc

02/02/17 / #20170029782

Devices and methods for separating particles

Devices for non-invasive, label-free separation of particles in liquid, including circulating tumors cells in blood, are provided. Embodiments of the disclosure provide for devices employing magnetic fluids and magnets for separation of circulating tumor cells from blood. Methods for separation of particles including circulating tumor cells are also provided.... University Of Georgia Research Foundation Inc

01/19/17 / #20170014361

Mitochondrial delivery of 3-bromopyruvate

A mitochondria targeted gold nanoparticle (T-3-BP-AuNP) decorated with 3-bromopyruvate (3-BP) and delocalized lipophilic triphenylphosphonium (TPP) cations to target the mitochondrial membrane potential (Δψm) was developed for delivery of 3-BP to cancer cell mitochondria by taking advantage of higher Δψm in cancer cell compared to normal cells. This construct showed remarkable... University Of Georgia Research Foundation Inc

01/12/17 / #20170008977

Glycopeptide and uses thereof

A glycolipopeptide comprising a carbohydrate component, a peptide component and a lipid component, for use as a therapeutic or prophylactic vaccine. Also provided are monoclonal and polyclonal antibodies that recognize the glycolipopeptide of the invention, as well as uses thereof.... University Of Georgia Research Foundation Inc

01/12/17 / #20170013751

Southern highbush blueberry plant named 'th-917'

... University Of Georgia Research Foundation Inc

01/05/17 / #20170000740

Combination therapeutic nanoparticles

... University Of Georgia Research Foundation Inc








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