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University Of Leicester patents


Recent patent applications related to University Of Leicester. University Of Leicester is listed as an Agent/Assignee. Note: University Of Leicester may have other listings under different names/spellings. We're not affiliated with University Of Leicester, we're just tracking patents.

ARCHIVE: New 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 | Company Directory "U" | University Of Leicester-related inventors


Aortopathy

The invention relates to aortopathy, and in particular, to compositions and methods for the diagnosis and treatment of aortopathy.... University Of Leicester

Monoclonal antibodies, compositions and methods for detecting mucin-like protein (mlp) as a biomarker for ovarian and pancreatic cancer

In various embodiments the invention provides anti-mucin-like protein (MLP) monoclonal antibodies, compositions and methods for detecting MLP as a biomarker for mucin-secreting type of cancer such as ovarian or pancreatic cancer.... University Of Leicester

Methods for inhibiting angiogenesis in a subject in need thereof

In one aspect, the present invention provides methods for preventing, treating, reverting and/or delaying angiogenesis in a mammalian subject suffering from, or at risk for developing, an angiogenesis-dependent disease or condition, comprising administering to the subject an amount of a MASP-2 inhibitory agent effective to inhibit angiogenesis. In some embodiments... University Of Leicester

Methods for treating conditions associated with masp-2 dependent complement activation

In one aspect, the invention provides methods of inhibiting the effects of MASP-2-dependent complement activation in a living subject. The methods comprise the step of administering, to a subject in need thereof, an amount of a MASP-2 inhibitory agent effective to inhibit MASP-2-dependent complement activation. In some embodiments, the MASP-2... University Of Leicester

Methods for inhibiting fibrosis in a subject in need thereof

In one aspect, the invention provides methods for treating, inhibiting, alleviating or preventing fibrosis in a mammalian subject suffering, or at risk of developing a disease or disorder caused or exacerbated by fibrosis and/or inflammation. In one embodiment, the invention provides methods of treating a subject suffering from renal fibrosis.... University Of Leicester

Csn5 polypeptides and uses thereof for screening therapeutic agents

The present invention relates to mutated CSN5 polypeptides and their use in a method of screening modulators of CSN5 activity that could be used as therapeutic agents.... University Of Leicester

Methods for treating conditions associated with masp-2 dependent complement activation

In one aspect, the invention provides methods of inhibiting the effects of MASP-2-dependent complement activation in a living subject. The methods comprise the step of administering, to a subject in need thereof, an amount of a MASP-2 inhibitory agent effective to inhibit MASP-2-dependent complement activation. In some embodiments, the MASP-2... University Of Leicester

Methods for treating disseminated intravascular coagulation by inhibiting masp-2 dependent complement activation

In one aspect, the invention provides methods of inhibiting the effects of MASP-2-dependent complement activation in a living subject. In one embodiment, the invention provides methods of treating a subject suffering from a complement mediated coagulation disorder, such as disseminated intravascular coagulation. The methods comprise the step of administering, to... University Of Leicester

Methods for inhibiting fibrosis in a subject in need thereof

In one aspect, the invention provides methods for treating, inhibiting, alleviating or preventing fibrosis in a mammalian subject suffering, or at risk of developing a disease or disorder caused or exacerbated by fibrosis and/or inflammation. In one embodiment, the invention provides methods of treating a subject suffering from renal fibrosis.... University Of Leicester

Senescent cell biomarkers

The invention relates to senescent cell biomarkers and the uses thereof. The invention also extends to methods and kits for detecting senescence, and drug conjugates and pharmaceutical compositions for killing senescent cells.... University Of Leicester

System for a brain-computer interface

The invention provides a two-step approach to providing a BCI system. In a first step the invention provides a low-power implantable platform for amplifying and filtering the extracellular recording, performing analogue to digital conversion (ADC) and detecting action potentials in real-time, which is connected to a remote device capable of... University Of Leicester

Methods for treating conditions associated with masp-2 dependent complement activation

In one aspect, the invention provides methods of inhibiting the effects of MASP-2-dependent complement activation in a living subject. The methods comprise the step of administering, to a subject in need thereof, an amount of a MASP-2 inhibitory agent effective to inhibit MASP-2-dependent complement activation. In some embodiments, the MASP-2... University Of Leicester

Methods for treating conditions associated with masp-2 dependent complement activation

In one aspect, the invention provides methods of inhibiting the effects of MASP-2-dependent complement activation in a living subject. The methods comprise the step of administering, to a subject in need thereof, an amount of a MASP-2 inhibitory agent effective to inhibit MASP-2-dependent complement activation. In some embodiments, the MASP-2... University Of Leicester

Methods for treating conditions associated with masp-2 dependent complement activation

In one aspect, the invention provides methods of inhibiting the effects of MASP-2-dependent complement activation in a living subject. The methods comprise the step of administering, to a subject in need thereof, an amount of a MASP-2 inhibitory agent effective to inhibit MASP-2-dependent complement activation. In some embodiments, the MASP-2... University Of Leicester

Solder flux

There is provided the use of at least one ionic liquid as a soldering/brazing flux. There is also provided a method of soldering a metal comprising applying a solder/braze comprising a flux to a surface of the metal and heating said metal to a desired soldering/brazing temperature, wherein the soldering/brazing... University Of Leicester

Methods for treating conditions associated with masp-2 dependent complement activation

In one aspect, the invention provides methods of inhibiting the effects of MASP-2-dependent complement activation in a human subject suffering from TMA associated with hematopoietic stem cell transplant. The methods comprise the step of administering, to a subject in need thereof, an amount of a MASP-2 inhibitory agent effective to... University Of Leicester

Genetically modified non-human mammals and cells

Genetically modified mammals are described which lack the mannan binding lectin associated serine protease MASP-2, together with methods and constructs for their production. Such mammals are useful as models for disorders of the complement system, and in the identification of treatments for such disorders. Also described are mammals which lack... University Of Leicester

Ecg evaluation

A method for assessing the electrical function of a heart, a method for determining a subject's need for the implantation of an implantable cardioverter defibrillator or the need for administration of an anti-arrhythmic agent, and apparatus for assessing the function of the heart and a computer program product. The methods... University Of Leicester

Improvements in or relating to structured illumination microscopy utilising acousto-optic deflectors

An apparatus (10) for structured illumination microscopy (SIM) comprises a pulsed femtosecond MiTai laser (11) operable to generate a pulsed beam. The beam pulses are directed on to a specimen (12) via an optical arrangement including a beam steering apparatus comprising a pair of acousto-optic deflectors AODx, AODy, each operable... University Of Leicester

Tanning of substrates using ionic liquids

The invention provides a process for tanning a substrate using at least one ionic liquid. The at least one ionic liquid can be used in at least one of the following tanning steps: tanning, re-tanning, preservation, liming, pickling, impregnation, lubrication, dyeing, fatliquoring or finishing.... University Of Leicester

In-bottle detection method

This invention relates to a method for analysing a liquid when inside a container in order to detect counterfeiting or adulteration of the liquid, the container being at least partially transparent to visible light. The method comprises the steps of: (a) measuring a first transmission spectrum through the container and... University Of Leicester








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