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University Of Miami
University Of Miami Office Of Technology Transfer
University Of Miami A Florida Non profit Corporation
University Of Miami Intellectual Property Strategy And Licensing Ipsl
University Of Miami Office Of Technology Transfer University Of Miami School Of Medicine
University Of Miami_20100107

University Of Miami patents


Recent patent applications related to University Of Miami. University Of Miami is listed as an Agent/Assignee. Note: University Of Miami may have other listings under different names/spellings. We're not affiliated with University Of Miami, we're just tracking patents.

ARCHIVE: New 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 | Company Directory "U" | University Of Miami-related inventors


Kits and methods for pathogen detection

Kits and methods for detecting pathogens without the need for laboratory equipment are disclosed. The kits and methods described herein allow for near-room temperature amplification of pathogen polynucleotides in a biological sample in a one-compartment reaction vessel. The kits and methods may be used to detect any target nucleic acid,... University Of Miami

Treatment of cardiac remodeling and other heart conditions

The present disclosure provides novel methods for treating cardiac remodeling and heart conditions using specific compounds, as well as compositions, and pharmaceutical formulations. In some embodiments, the compounds may inhibit acetylation of MEF2 transcription factors.... University Of Miami

Biodegradable oceanic drifter tracking device

A water body drifter device for tracking movement of a fluid is disclosed. The drifter may include a floater assembly having a toroid shaped buoy fixedly connected to a floater head disposed interiorly to the toroid shaped buoy, the floater head having a recess and a cap sealably attached to... University Of Miami

Materials and methods for treating endothelial dysfunction and methods for monitoring efficacy of therapy in a subject

The present disclosure is directed to materials and methods for treating endothelial dysfunction in a subject in need thereof. Methods of determining efficacy of treatment are also provided.... University Of Miami

Cell culture media

A cell culture medium comprising adenosine triphosphate; a carrier protein; cholesterol, linoleic acid, and lipoic acid; glutathione; at least one nucleotide salvage pathway precursor base; phosphoethanolamine; selenium; transferrin; triiodothyronine; all-trans-retinoic acid (ATRA) and vitamin C; zinc, magnesium, and copper; an agent that increases intracellular cAMP; epidermal growth factor (EGF); hydrocortisone;... University Of Miami

Purification of carbon nanotubes via selective heating

The present invention provides methods for purifying a layer of carbon nanotubes comprising providing a precursor layer of substantially aligned carbon nanotubes supported by a substrate, wherein the precursor layer comprises a mixture of first carbon nanotubes and second carbon nanotubes; selectively heating the first carbon nanotubes; and separating the... University Of Miami

Apparatus, system, and 4-dimensional molecular printing

A method and apparatus for 4-dimensional printing are disclosed. The apparatus includes a polymer pen array translatable in three axes, a light source for illuminating the polymer pen array, a reactive surface disposed opposite the polymer pen array, and a flow-through microfluidic cell having a reactive chamber in fluid communication... University Of Miami

Interleukin-2/interleukin-2 receptor alpha fusion proteins and methods of use

Various methods and compositions are provided which can be employed to modulate the immune system. Compositions include a fusion protein comprising: (a) a first polypeptide comprising Interleukin-2 (IL-2) or a functional variant or fragment thereof; and (b) a second polypeptide, fused in frame to the first polypeptide, wherein the second... University Of Miami

Method for in vivo expansion of t regulatory cells

Compositions specific for TNF-receptor superfamily member 25 (TNFRSF25, DR3) modulate the immune response by regulating T regulatory cells.... University Of Miami

Methods for modulating iks channel activity

Disclosed herein are methods of using polyunsaturated fatty acids and derivatives thereof (“PUFAs”) to modulate Iks channels to treat conditions associated with a disruption in Iks channel activity, such as cardiac arrhythmias. In particular, disclosed herein are negatively charged PUFAs having decreased pKa values, which can activate (i.e., open) IKs... University Of Miami

Materials and methods of treating dyslipidemia

Described herein are materials and methods for treating dyslipidemia in a mammalian subject in need thereof comprising administering a growth hormone-releasing hormone (GHRH) antagonist or variant thereof to the subject.... University Of Miami

Perforin 2 defense against invasive and multidrug resistant pathogens

Perforin-2 (P2) is expressed by fibroblasts, microglia and macrophages and was found to be responsible for killing bacteria, for example, Mycobacteria smegmatis, M. avium, Salmonellae, MRSA (drug resistant Stapholococci), E. coli. Compounds identified by screening assays are selected based on the effects of these compounds on P2. Use of these... University Of Miami

Methods and compositions for transgene expression in a herpesvirus vector system

Compositions are provided comprising a replication-competent herpesvirus vector system and/or a herpesvirus vector particle comprising a heterologous recombinant transgene of interest encoding an antigen of interest (e.g., a tumor-associated antigen, a microbial antigen, etc.), wherein the recombinant transgene has been modified to comprise a codon usage signature of a herpesvirus... University Of Miami

Antibody-endostatin fusion protein and its variants

Methods of inhibiting the growth of tumors comprising administering chimeric fusion molecules comprising endostatin mutants and all or a portion of anti-Her2 or anti-EGFR antibodies.... University Of Miami

Compositions, kits and methods for in vitro antigen presentation, assessing vaccine efficacy, and assessing immunotoxicity of biologics and drugs

Nanoparticle-based compositions, assays, kits, methods and platforms for delivering an antigen (peptides, proteins) or a nucleic acid encoding an antigen to professional APCs (PAPCs) result in the generation of autologous APCs that present a natural peptide repertoire of the antigen for use in assessing the efficacy of a vaccine (e.g.,... University Of Miami

Rapid identification of pharmacological targets and anti-targets for drug discovery and repurposing

A computing system automatically analyzes various drug or other compound targets using biologic activity data for cellular proteins, and develops a target/anti-target matrix identifying pharmacologically responsive targets intended for drug engagement, and pharmacologically responsive anti-targets intended for avoidance of drug engagement. The system separates compounds into subsets based on biological... University Of Miami

Methods of modulating inflammasome activity to treat inflammatory conditions

Compositions and methods for reducing inflammation in the central nervous system (CNS) of a mammal that has been subjected to a stroke, traumatic injury to the CNS such as traumatic brain injury (TBI), spinal cord injury (SCI), or having an autoimmune or CNS disease have been developed. The compositions and... University Of Miami

Expanded utility of red-cell derived microparticles (rmp) for treatment of bleeding

Red blood cell membrane derived microparticles (RMP) are safe, economical, effective hemostatic agents in the treatment of a wide range of bleeding conditions and can, therefore, be considered as universal hemostatic agents. Effective RMP are produced from red blood cells using a high-pressure extrusion membrane shear process. The RMP can... University Of Miami

Method and system for microfilter-based capture and release of cancer associated cells

A slotted microfilter is coated with a phase changeable material having a hydrophobic state under a first temperature and a hydrophilic state under a second temperature. An example coating material is poly(N-isopropylacrylamide) (“PIPAAm”). The microfilter can be controlled to switch between a capture state where circulating tumor cells are captured... University Of Miami

Image guided small animal stereotactic radiation treatment system

A dual, imaging and radiation system provides for finely aligned movement of a subject through the use of a computer controlled mounting stage having separate, non-gantry translational and rotational controllable movement. The system cycles a subject tissue between a treatment position where radiation doses are applied and an imaging position... University Of Miami

Innate immune proteins as biomarkers for cns injury

The present invention provides novel markers of the severity of a central nervous system injury, such as spinal cord injury or traumatic brain injury, in a patient. In particular, protein components of inflammasomes in the cerebrospinal fluid that can be used to assess the serverity of central nervous system injury... University Of Miami








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