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University Of Southampton patents


Recent patent applications related to University Of Southampton. University Of Southampton is listed as an Agent/Assignee. Note: University Of Southampton may have other listings under different names/spellings. We're not affiliated with University Of Southampton, we're just tracking patents.

ARCHIVE: New 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 | Company Directory "U" | University Of Southampton-related inventors


Cleaning apparatus and method using an acoustic transducer

An apparatus and method for cleaning a surface, the apparatus comprising: a body defining a cavity, the body terminating in a distal end that is adapted, in use, to be in the vicinity of a surface to be cleaned such that the surface to be cleaned forms an end wall of a chamber including the cavity; at least one cleaning liquid inlet for flow of a cleaning liquid into the chamber; a divider located in or at the end of the cavity that divides the chamber into a first portion and a second portion, the second portion, in use, being in fluid communication with the surface to be cleaned; and an acoustic transducer associated with the first portion of the chamber to introduce acoustic energy into the chamber; wherein the divider is adapted to permit the passage of acoustic energy therethrough from the first portion of the chamber to the second portion of the chamber to thereby allow pressure fluctuations to be generated at the surface to be cleaned.. . ... University Of Southampton

Flip-flop

A single-phase flip-flop comprising: a master latch comprising: a first circuit to generate a master latch signal in response to a first master logic operation on a flip flop input signal and a first clock signal, and a second circuit to generate a master output signal in response to a second master logic operation on the first clock signal and master latch signal; a slave latch comprising: a third circuit to generate a slave output signal in response to a first slave logic operation on the first clock signal and one of the master output signal and an inverted slave output signal; and wherein the master latch is configured to capture the flip-flop input signal during a first portion of the first clock signal and the slave latch is configured to capture the master output signal during a second portion of the first clock signal.. . ... University Of Southampton

Fluid flow device on a porous substrate and method for making the same

A method of making a fluid flow device comprises providing a substrate of porous material, depositing a radiation-sensitive substance onto the substrate in a pattern defining one or more regions intended to receive and contain fluid during use of the device or occupying an area within such a region, such that the radiation-sensitive substance extends at least partly through the thickness of the substrate below the pattern, and exposing radiation onto the substrate thereby delivering energy to the radiation-sensitive substance in at least part of the pattern to change the radiation-sensitive substance from a first state to a second state through at least part of the thickness of the substrate. One of the first state and the second state may be less permeable than the other.. ... University Of Southampton

Reducing intron retention

Disclosed herein are methods, compositions, polynucleic acid polymers, assays, and kits for inducing processing of a partially processed mrna transcript to remove a retained intron to produce a fully processed mrna transcript that encodes a full-length functional form of a protein. Also described herein are methods and compositions for treating a disease or condition characterized by impaired production of a full-length functional form of a protein or for treating a disease or condition characterized by a defective splicing in a subject.. ... University Of Southampton

Optical (de)multiplexers

An optical demultiplexer/multiplexer, comprising: a multimode interference waveguide; at least one first coupling waveguide which meets the multimode interference waveguide at at least one first location and a plurality of second coupling waveguides which meet the multimode interference waveguide at a plurality of second locations which are spaced in a direction of transmission in relation to the at least one first location, with the at least one first coupling waveguide and the second coupling waveguides together with the multimode interference waveguide providing a first angled multimode interferometer which operates to demultiplex a first optical signal having optical channels of a plurality of wavelengths or multiplex optical signals of a plurality of wavelengths into a first optical signal having optical channels of the plurality of wavelengths; at least one third coupling waveguide which meets the multimode interference waveguide at at least one third location and a plurality of fourth coupling waveguides which meet the multimode interference waveguide at a plurality of fourth locations which are spaced in a direction of transmission in relation to the at least one third location, with the at least one third coupling waveguide and the plurality of fourth coupling waveguides together with the multimode interference waveguide providing a second angled multimode interferometer which operates to demultiplex a second optical signal having optical channels of a plurality of wavelengths or multiplex optical signals of a plurality of wavelengths into a second optical signal having optical channels of the plurality of wavelengths; whereby the demultiplexer/multiplexer provides for the demultiplexing/multiplexing of first and second optical signals having optical channels of a plurality of wavelengths. In a further embodiment the first coupling waveguide of an optical demultiplexer/multiplexer comprising. ... University Of Southampton

Modular electronic structures

A modular structural member (100) comprising: at least two connection portions (102), and a structural portion (101), the connection portions arranged to provide electrical and mechanical connection to other structural members, and wherein, electronic componentry (125) is provided on the structural portion, and/or the connection portions are arranged to receive a fastener (240; 260), to connect multiple connection portions together, which is provided with electronic componentry, and further wherein, a plurality of the structural members arranged to be connected together to form a structure.. . ... University Of Southampton

Melt-growth of single-crystal alloy semiconductor structures and semiconductor assemblies incorporating such structures

A method of fabricating at least one single-crystal alloy semiconductor structure, comprising: forming at least one seed on a substrate for growth of at least one single-crystal alloy semiconductor structure, the at least one seed containing an alloying material; providing at least one structural form on the substrate which is crystallized to form the at least one single-crystal alloy semiconductor structure, the at least one structural form being formed of a host material and comprising a main body which extends from the at least one seed and a plurality of elements which are connected in spaced relation to the main body; heating the at least one structural form such that the material of the at least one structural form has a liquid state; and cooling the at least one structural form, such that the material of the at least one structural form nucleates at the least one seed and crystallizes as a single crystal to provide at least one single-crystal alloy semiconductor structure, with a growth front of the single crystal propagating in the main body of the respective structural form away from the respective seed; wherein the plurality of elements of each structural form provide reservoirs of the alloying material in liquid state, such that successive ones of the plurality of elements act to maintain, in liquid state, an available supply of the alloying material to the growth front of the single crystal in the main body of the respective structural form.. . ... University Of Southampton

Hollow-core optical fibers

An anti-resonant hollow-core fiber comprising a first tubular, cladding element which defines an internal cladding surface, a plurality of second tubular elements which are attached to the cladding surface and together define a core with an effective radius, the second tubular elements being arranged in spaced relation and adjacent ones of the second tubular elements having a spacing therebetween, and a plurality of third tubular elements, each nested within a respective one of the second tubular elements.. . ... University Of Southampton

Modified antibodies containing modified igg2 domains which elicit agonist or antagonistic properties and use thereof

Through a combination of in vitro and in vivo approaches, the inventors show that human igg2 (h2) delivers unique fcγr-independent agonistic activity to anti-cd40 antibodies and to antibodies specific to other immunostimulatory receptors, including 4-1bb and cd28. Investigation of an anti-human cd40 mab, lob7.4, revealed that the unique activity of h2 was dependent upon the precise arrangement of hinge and ch1 disulfide bonds. ... University Of Southampton

Optical fibre assembly and method of making an optical fibre assembly

A method of forming an optical fibre assembly, comprises providing a planar substrate made of a first material; positioning an optical fibre with an outer layer of a first glass material on a surface of the substrate to form a pre-assembly; depositing a further glass material such as silica soot onto the pre-assembly, over at least a part of the optical fibre and adjacent parts of the substrate surface; and heating the pre-assembly to consolidate the further glass material into an amorphous volume in contact with at least parts of the surface of the substrate and the outer layer of the optical fibre, thereby bonding the optical fibre to the substrate to create the optical fibre assembly.. . ... University Of Southampton

Peptide-induced nk cell activation

This invention relates to nk cell activation and nk cell mediated immunity, immunogenic peptides, compositions and complexes; and associated methods of treatment or prophylaxis. In particular, a peptide capable of activating nk cell-mediated immunity, the peptide comprising or consisting of the amino acid sequence xnax2x1 wherein xn is an amino acid sequence of between 5 and 12 residues, and x1 is any amino acid; or leucine or isoleucine; and x2 is alanine, threonine, tryptophan, or serine.. ... University Of Southampton

Fluid flow device with flow control and method for making the same

A method of making a fluid flow device comprises: providing a substrate of porous material (2) impregnated with a light-sensitive substance (5) in a first state and which is configured to change from the first state to a second state when exposed to light (3), the second state being a solid state that is resistant to a solvent and the first being removable with the solvent; the substrate having a fluid flow channel (7) defined therein, the channel having a depth; exposing a beam of light (3) onto an area of the substrate surface within the fluid flow channel to deliver energy to a volume of the substrate below the area to change the light-sensitive substance to the second state; during exposure, creating a partial barrier to flow of fluid along the channel by controlling the amount of energy delivered to the volume below at least part of the area to change the light-sensitive substance to the second state in a volume of the substrate within the fluid flow channel that has a depth less than the depth of the fluid flow channel; and developing the substrate in the solvent to leave the light-sensitive substance which is in the solid state and remove the light-sensitive substance which is in the other state. The device may be a medical diagnostic device, and the substrate may be a paper substrate or may be a nitrocellulose substrate.. ... University Of Southampton

Modulation of gene expression and screening for deregulated protein expression

Disclosed herein include compositions and methods of modulating protein expression that utilizes an activator or a repressor of a non-sense mediated rna decay switch exon (nse). In some embodiments, also included herein are compositions and methods of modulating protein expression that uses an agent that targets a transposed element.. ... University Of Southampton

Nanoparticle catalysts for conversion of cyclohexanol to cyclohexanone

Methods for converting an alcohol, such as cyclohexanol to a ketone, such as cyclohexanone, include reacting the alcohol in the presence of a catalyst and oxygen to produce the ketone. In one exemplary embodiment, the catalyst comprises a microporous copper chloropyrophosphate framework including a plurality of noble metal nanoparticles. ... University Of Southampton

03/16/17 / #20170076014

A method of mapping images of human disease and of designing or selecting a medical device using a surrogate model

A method of designing or selecting an implantable medical device comprises the steps of: i) obtaining a plurality of measured data points of a characteristic of an anatomical feature of an individual; ii) using said data points to construct a surrogate model of said characteristic, the surrogate model being constructed by interpolating or regressing measured data points of the characteristic, and using said surrogate model to obtain predicted values of said characteristic at a plurality of locations; iii) using said predicted values to determine or select at least one value of a design parameter of the implantable medical device. There is further disclosed a method of monitoring or diagnosing a disease or disorder.. ... University Of Southampton

02/23/17 / #20170052146

Methods and apparatus for introducing a sample into a separation channel for electrophoresis

Methods and apparatus for introducing a sample into a separation channel for electrophoresis are disclosed. In one arrangement sample droplets having a membrane that encapsulates a sample are formed and brought to an injection position in contact with a transport medium of a separation channel. ... University Of Southampton

02/23/17 / #20170050187

Methods and apparatus for generating droplets

Methods and apparatus for generating droplets are disclosed. In one arrangement a peristaltic screw pump is configured to drive pulsatile flows of fluids in different conduits which are phased relative to each other such that a sequence of droplets are formed at a junction downstream from the pump.. ... University Of Southampton

02/16/17 / #20170043058

Polymer-clay composite and organoclay

The invention relates to a polymer-clay composite material comprising clay nanoparticles and a polymer, and wherein (a) the polymer comprises phosphate and/or phosphonate ligands; or (b) the polymer-clay composite further comprises linker molecules comprising a phosphate or phosphonate ligand, wherein the linker molecules are arranged to be anchored to the polymer. The invention further relates to organoclays, bmp-clay composite material. ... University Of Southampton








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