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University Of Tennessee Research Foundation
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University Of Tennessee Research Foundation patents


Recent patent applications related to University Of Tennessee Research Foundation. University Of Tennessee Research Foundation is listed as an Agent/Assignee. Note: University Of Tennessee Research Foundation may have other listings under different names/spellings. We're not affiliated with University Of Tennessee Research Foundation, we're just tracking patents.

ARCHIVE: New 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 | Company Directory "U" | University Of Tennessee Research Foundation-related inventors


Method and constructing a neuroscience-inspired artificial neural network with visualization of neural pathways

A method and apparatus for constructing one of a neuroscience-inspired artificial neural network and a neural network array comprises one of a neuroscience-inspired dynamic architecture, a dynamic artificial neural network array and a neural network array of electrodes associated with neural tissue such as a brain, the method and apparatus... University Of Tennessee Research Foundation

Redox flow battery with increased-surface-area electrode and asymmetric electrolyte concentration

A flow battery having stable electrochemical performance is provided. The flow battery includes a separator disposed between a positive electrode and a negative electrode, a first flow plate to distribute a positive electrolyte to the positive electrode, and a second flow plate to distribute a negative electrolyte to the negative... University Of Tennessee Research Foundation

Selective androgen receptor degrader (sard) ligands and methods of use thereof

This invention is directed to pyrrole, pyrazole, imidazole, triazole, and morpholine based selective androgen receptor degrader (SARD) compounds including heterocyclic anilide rings and their synthetic precursors, R-isomers, and non-hydroxylated and/or non-chiral propanamides, and pharmaceutical compositions and uses thereof in treating prostate cancer, advanced prostate cancer, castration resistant prostate cancer, triple... University Of Tennessee Research Foundation

Scn plants and methods for making the same

The invention relates to genes which may be utilized for resistance to soybean cyst nematode. More specifically the present disclosure relates to identification of gene(s) that can confer upon a soybean plant resistance to soybean cyst nematode (SCN) and methods to use these loci and genes to obtain soybean strains... University Of Tennessee Research Foundation

Diagnosing and treating iga nephropathy

Provided are methods of diagnosing IgA nephropathy in a subject. Optionally, the methods comprise isolating an IgG from the subject and determining whether the IgG binds to a galactose-deficient IgA1. Optionally, the methods comprise providing a biological sample from the subject and detecting in the sample a mutation in a... University Of Tennessee Research Foundation

Surface-functionalized polyolefin fibers and their use in methods for extracting metal ions from liquid solutions

A fiber useful in the absorption of metal ions from aqueous solutions, the fiber comprising a polyolefin backbone having a diameter of at least 1 micron and having covalently appended on its surface halogen atoms and vinyl-addition polymeric grafts functionalized with metal-binding groups, such as at least one functional group... University Of Tennessee Research Foundation

Methods and compositions for preventing and treating tooth erosion

Methods and compositions are provided for reducing, treating or preventing dental erosion in a patient in need of such treatment, the methods and compositions comprising administering a therapeutically effective amount of an alkalinizing agent and a re-mineralizing agent to the teeth.... University Of Tennessee Research Foundation

System and high frequency leakage reduction through selective harmonic elimination in electrosurgical generators

An electrosurgical generator includes: a power supply configured to output a DC waveform; an inverter coupled to the power supply, the inverter including a plurality of switching elements; and a controller coupled to the inverter and configured to generate a switching angle waveform including a plurality of switching pulses. The... University Of Tennessee Research Foundation

Compositions, producing nanoalloys and/or nanocomposites using tandem laser ablation synthesis in solution-galvanic replacement reaction

Compositions, systems, and methods for producing nanoalloys and/or nanocomposites using tandem laser ablation synthesis in solution-galvanic replacement reaction (LASiS-GRR) are disclosed. The method may include disposing a first metal composition within a reaction cell, adding a quantity of a second metal composition into the reaction cell, ablating, with a laser,... University Of Tennessee Research Foundation

In situ gelling form for long-acting drug delivery

The present invention relates to an injectable polymer matrix drug delivery system comprising a biodegradable polymer, a solvent or a combination of solvents, and an active pharmaceutical ingredient.... University Of Tennessee Research Foundation

Carbonation of metal silicates for long-term co2 sequestration

In a preferred embodiment, the invention relates to a process of sequestering carbon dioxide. The process comprises the steps of: (a) reacting a metal silicate with a caustic alkali-metal hydroxide to produce a hydroxide of the metal formerly contained in the silicate; (b) reacting carbon dioxide with at least one... University Of Tennessee Research Foundation

Targeting immunotherapy for amyloidosis

Disclosed are methods and compositions for targeting antibodies to amyloid deposits. For example, amyloid-reactive peptides that bind amyloid deposits are administered to a subject. Antibodies to the amyloid-reactive peptides are then administered to the subject. Upon administration of the antibodies, the amyloid-reactive peptides bind the antibodies and thus pre-target the... University Of Tennessee Research Foundation

Inhibitory peptides of viral infection

Disclosed are methods of treating and/or inhibiting a viral infection in a subject. The methods include administering a therapeutically effective amount of heparin-binding peptide. Also disclosed herein are methods for blocking viral binding to a cell. Further disclosed are anti-viral compositions for administration to a subject infected with a virus.... University Of Tennessee Research Foundation

Comprehensive process for selectively separating lignocellulosic biomass into purified components with high yield

A comprehensive process for treating lignocellulosic biomass in order to separate the biomass into its component parts, the process comprising: a) contacting the lignocellulosic biomass with a first solvent for a period of time and at a first temperature at a severity in the range of about 2 to about... University Of Tennessee Research Foundation

Selective androgen receptor modulator and methods of use thereof

This invention provides substituted acylanilide compounds and uses thereof in treating a variety of diseases or conditions in a subject including, inter alia, a muscle wasting disease and/or disorder such as Duchenne muscular dystrophy or Becker muscular dystrophy.... University Of Tennessee Research Foundation

Compounds for treatment of cancer

The present invention relates to novel compounds having anti-cancer activity, methods of making these compounds, and their use for treating cancer and drug-resistant tumors, e.g. melanoma, metastatic melanoma, drug resistant melanoma, prostate cancer and drug resistant prostate cancer.... University Of Tennessee Research Foundation

Intrinsic and activated a4bx6 scintillators

Mixed halide scintillation materials of a first general formula A4B(1-y)MyX′6(1-z)X″6z and a second general formula A(4-y)BMyX′6(1-z)X″6z are disclosed. In the general formulas, A is an alkali metal, B is an alkali earth metal, and X′ and X″ are two different halogen atoms. Scintillation materials of the first general formula include... University Of Tennessee Research Foundation

Radiation detector for imaging applications with stabilized light output

A radiation detection system may include a detector. The detector may include a scintillator to convert ionizing radiation, which originates externally to the detector, into visible light, a sensor configured to detect the visible light from the scintillator, and a light source. The radiation detection system may further include a... University Of Tennessee Research Foundation

Flex roller-crimper for improved management and termination of cover crops and other plant material

Herein is described an agricultural device that can include a frame; and a plurality of roller-crimping devices supported by the frame arranged in at least one row oriented in a direction that is transverse to a direction of travel of the agricultural device. Each of the plurality of roller-crimping devices... University Of Tennessee Research Foundation

System and harmonic control of dual-output generators

A dual-output generator is configured to output two or more waveforms at different frequencies. In particular, the dual-output generator is configured to provide low-frequency output, which may be suitable for ultrasonic surgical instruments, and a high-frequency output, which may be suitable for electrosurgical instruments, while reducing the amplitude of all... University Of Tennessee Research Foundation

Tampering detection and location identification of digital audio recordings

Systems and methods for detecting a tampering and identifying a location of a digital recording are provided. A frequency sequence and a phase angle sequence may be extracted from the digital recording. A portion of the frequency sequence may be matched to one of a plurality of reference frequency sequences,... University Of Tennessee Research Foundation

Ternary metal halide scintillators

Metal halide scintillators are described. More particularly, the scintillators include doped (e.g., europium-doped) ternary metal halides, such as those of the formulas A2BX4 and AB2X5, wherein A is an alkali metal, such as Li, Na, K, Rb, Cs or any combination thereof; B is an alkali earth metal, such as... University Of Tennessee Research Foundation

Methods for improvement of semen quality

A method for improving quality of a mammalian semen sample includes providing an insoluble carrier carrying at least one ligand that binds to an indicator of impaired sperm membrane integrity and/or motility, or the insoluble carrier carrying at least one molecule capable of binding to the at least one ligand,... University Of Tennessee Research Foundation

Multigraft copolymer superelastomers by emulsion polymerization

Multigraft copolymers having various structures, e.g., comb and centipede structures, can be prepared from emulsion copolymerization of monomers and macromonomers. The emulsion copolymerization can be initiated by a thermally activated radical initiator or a redox initiation system. The multigraft copolymers can have high molecular weight and/or a large number of... University Of Tennessee Research Foundation

Iron nitride magnetic material including coated nanoparticles

The disclosure describes techniques for forming nanoparticles including Fe16N2 phase. In some examples, the nanoparticles may be formed by first forming nanoparticles including iron, nitrogen, and at least one of carbon or boron. The carbon or boron may be incorporated into the nanoparticles such that the iron, nitrogen, and at... University Of Tennessee Research Foundation

Selective androgen receptor degrader (sard) ligands and methods of use thereof

This invention provides novel indole, indazole, benzimidazole, indoline, quinolone, isoquinoline, and carbazole selective androgen receptor degrader (SARD) compounds, pharmaceutical compositions and uses thereof in treating prostate cancer, advanced prostate cancer, castration resistant prostate cancer, other AR-expressing cancers, androgenic alopecia or other hyper androgenic dermal diseases, Kennedy's disease, amyotrophic lateral sclerosis... University Of Tennessee Research Foundation

Transient stability simulation and operation of power systems

Systems and methods for simulating and operating a power system following a contingency are provided. Semi-analytic solutions (SASs) for the power system state variables may be derived offline for a plurality of contingencies. Following a contingency, the SASs may be evaluated online, faster than real time, to study transient stability... University Of Tennessee Research Foundation

Nanocomposite electrode material for proton conducting fuel cell

An electrode includes a proton conducting electrolyte phase, an electronic conducting phase, and a metal or metal alloy catalyst in contact with each of the phases. The electronic conducting phase is infiltrated with the proton conducting electrolyte phase such that the phases form a solid nanocomposite with bulk electronic conductivity.... University Of Tennessee Research Foundation

Nanocomposite electrode material for proton conducting electrochemical devices

An electrode includes a proton conducting electrolyte phase, an electronic conducting phase, and a metal catalyst, metal alloy catalyst, or metal oxide catalyst in contact with each of the phases. The electronic conducting phase is infiltrated with the proton conducting electrolyte phase such that the phases form a solid nanocomposite... University Of Tennessee Research Foundation

Selective androgen receptor degrader (sard) ligands and methods of use thereof

This invention provides novel 3-amino propanamide selective androgen receptor degrader (SARD) compounds, pharmaceutical compositions and uses thereof in treating prostate cancer, advanced prostate cancer, castration resistant prostate cancer, androgenic alopecia or other hyperandrogenic dermal diseases, Kennedy's disease, amyotrophic lateral sclerosis (ALS), and uterine fibroids, and to methods for reducing the... University Of Tennessee Research Foundation

Methods of plant transformation using transformable cell suspension culture and uses thereof

The subject invention pertains to a method of rapidly transforming a plant with a gene of interest. The method of the current invention comprises the steps of a) preparing a bacterial culture, wherein the bacterial culture comprises a vector containing the gene of interest, b) producing a plant cell suspension... University Of Tennessee Research Foundation

Methods for detecting a biomarker by alternating current electrokinetics

Methods are described for detecting pathogens, infectious diseases, and physiological conditions by quantifying change of impedance over time of when a biological sample is applied onto a lab-on-a-chip. The lab-on-a-chip utilizes alternating-current electrokinetic (ACEK) phenomena such that molecules move or are carried in an electric field generated by the application... University Of Tennessee Research Foundation

Selective androgen receptor degrader (sard) ligands and methods of use thereof

This invention provides novel indole, indazole, benzimidazole, indoline, quinolone, isoquinoline, and carbazole selective androgen receptor degrader (SARD) compounds, pharmaceutical compositions and uses thereof in treating prostate cancer, advanced prostate cancer, castration resistant prostate cancer, androgenic alopecia or other hyper androgenic dermal diseases, Kennedy's disease, amyotrophic lateral sclerosis (ALS), and uterine... University Of Tennessee Research Foundation

Treatment and prophylaxis of amyloidosis

Methods useful for effecting prophylaxis or treatment of amyloidosis, including AA Amyloidosis and AL amyloidosis, by administering peptides comprising neoepitopes, such as AA fragments from a C-terminal region of AA, and antibodies specific for neoepitopes of aggregated amyloid proteins, for example, antibodies specific for the C-terminal region of AA fibrils.... University Of Tennessee Research Foundation

Novel glycerol dehydration methods and products thereof

Methods and systems for suppressing coking in dehydration reactions catalyzed by solid acids. Dehydration reactions catalyzed by one or more solid acid catalysts can be performed in the presence of a super critical carbon dioxide medium which prevents or minimizes coking of the solid acid catalysts. Methods and systems are... University Of Tennessee Research Foundation

03/02/17 / #20170057930

Compounds for treatment of cancer

The present invention relates to colchicine-binding site compounds having anti-cancer activity, compositions comprising the same, and their use for treating various forms of cancer.... University Of Tennessee Research Foundation

03/02/17 / #20170058196

Mixed halide scintillators for radiation detection

Mixed halide scintillation materials of the general formula AB(1-y)MyX′wX″(3-w), where 0≦y≦1, 0.05≦w≦1, A may be an alkali metal, B may be an alkali earth metal, and X′ and X″ may be two different halogen atoms, and of the general formula A(1-y)BMyX′wX″(3-w), where 0≦y≦1, 0.05≦w≦1, A maybe an alkali metal, B... University Of Tennessee Research Foundation

02/23/17 / #20170050921

Selective androgen receptor degrader (sard) ligands and methods of use thereof

This invention provides novel 3-amino propanamide selective androgen receptor degrader (SARD) compounds, pharmaceutical compositions and uses thereof in treating prostate cancer, advanced prostate cancer, castration resistant prostate cancer, androgenic alopecia or other hyperandrogenic dermal diseases, Kennedy's disease, amyotrophic lateral sclerosis (ALS), and uterine fibroids, and to methods for reducing the... University Of Tennessee Research Foundation

02/16/17 / #20170043303

Cross-linked polymeric membranes for carbon dioxide separation

wherein R1, R2, R3, R4, R5, and R6 are independently selected from hydrocarbon groups having at least 1 and up to 6 carbon atoms; A1 and A2 are independently selected from cyclic hydrocarbon groups; L1 and L2 are linking groups or covalent bonds; n is an integer of at least... University Of Tennessee Research Foundation

02/02/17 / #20170029370

Selective androgen receptor degrader (sard) ligands and methods of use thereof

This invention provides novel indole, indazole, benzimidazole, indoline, quinolone, isoquinoline, and carbazole selective androgen receptor degrader (SARD) compounds, pharmaceutical compositions and uses thereof in treating prostate cancer, advanced prostate cancer, castration resistant prostate cancer, other AR-expressing cancers, androgenic alopecia or other hyper androgenic dermal diseases, Kennedy's disease, amyotrophic lateral sclerosis... University Of Tennessee Research Foundation

01/19/17 / #20170014370

Sarms and use thereof

This invention is directed to substituted acylanilide compounds and uses thereof in improving or preserving lung function and cardiac function in a subject suffering from Duchenne muscular dystrophy.... University Of Tennessee Research Foundation

01/19/17 / #20170014371

Sarms and use thereof

This invention is directed to substituted acylanilide compounds and uses thereof in treating muscular dystrophies such as Duchenne muscular dystrophy and Becker muscular dystrophy and in improving or preserving lung function and cardiac function in a subject suffering from Duchenne muscular dystrophy.... University Of Tennessee Research Foundation

01/19/17 / #20170016068

Single nucleotide polymorphisms (snp) and association with resistance to immune tolerance induction

This application discloses methods, systems and kits for correlating the presence or absence of certain nucleic acid sequences within a population with the ability to create immune tolerance in that same population. Tolerance can be induced by solo or repeated administration of antigen, including soluble antigens administered either intravenously or... University Of Tennessee Research Foundation

01/19/17 / #20170016940

Universal grid analyzer

Embodiments of the present invention may provide a device for monitoring electric power at the distribution level. The device may include an analog-to-digital converter (ADC) to convert an input signal into digital samples at time intervals, a receiver to generate a pulse-per-second (PPS) signal, an oscillator to generate an oscillator... University Of Tennessee Research Foundation

01/05/17 / #20170005170

Semiconductor composition containing iron, dysprosium, and terbium

An amorphous semiconductor composition includes 1 to 70 atomic percent iron, 15 to 65 atomic percent dysprosium, 15 to 35 atomic percent terbium, balance X, wherein X is at least one of an oxidizing element and a reducing element. The composition has an essentially amorphous microstructure, an optical transmittance of... University Of Tennessee Research Foundation








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