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Ventana Medical Systems Inc patents


Recent patent applications related to Ventana Medical Systems Inc. Ventana Medical Systems Inc is listed as an Agent/Assignee. Note: Ventana Medical Systems Inc may have other listings under different names/spellings. We're not affiliated with Ventana Medical Systems Inc, we're just tracking patents.

ARCHIVE: New 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 | Company Directory "V" | Ventana Medical Systems Inc-related inventors


 new patent  Opposables incorporating fluid control elements and automated specimen processing systems

Disclosed are specimen processing systems capable of processing specimens carried on slides. The specimen processing systems comprise opposables having at least one fluid control element. ... Ventana Medical Systems Inc

Assembly for storing and transporting tissue samples immersed in a fluid

A method and system for processing a sample in a fluid is provided. An assembly comprising a cap prefilled with a fixative solution, a valve, and a container for storing a tissue sample are provided. ... Ventana Medical Systems Inc

Descriptive measurements and quantification of staining artifacts for in situ hybridization

Immunohistochemistry (ihc) and in situ hybridization (ish) have the aim of detecting, localizing and quantifying certain analytes for various diagnostic purposes. The quality of the stains which are analyzed may deviate for various reasons. ... Ventana Medical Systems Inc

Haptens, hapten conjugates, compositions thereof and method for their preparation and use

A method for performing a multiplexed diagnostic assay, such as for two or more different targets in a sample, is described. One embodiment comprised contacting the sample with two or more specific binding moieties that bind specifically to two or more different targets. ... Ventana Medical Systems Inc

Compositions and methods for simultaneous inactivation of alkaline phosphatase and peroxidase enzymes during automated multiplex tissue staining assays

Disclosed are compositions and methods for inactivating one or more enzymes in a biological sample.. . ... Ventana Medical Systems Inc

Multiples multiplex immunohistochemical assay using primary antibodies of the same host species

Disclosed herein are methods and systems for detecting cd3 and cd16 in the same sample of a colorectal, head & neck, or lung tumor using immunohistochemical methods using primary antibodies from the same host species and secondary antibodies immunoreactive with antibodies of the host species of the primary antibodies. Methods to denature and block the first primary antibody contacted with the sample are provided.. ... Ventana Medical Systems Inc

Thermochemical-based antibody inactivation methods and systems

Methods, systems, compositions, and thermochemical processes for inactivating proteinaceous binding entities (pbes) such as antibodies in between staining cycles for preventing cross-reactivity in subsequent staining cycles. The thermochemical methods, compositions, or systems may feature incubating a sample in a solution comprising a buffer at a temperature sufficient to reduce or eliminate further detectability of the pbe. ... Ventana Medical Systems Inc

Inkjet deposition of reagents for histological samples

Devices and methods for the deposition of reagents onto cells or tissue samples are disclosed. Also disclosed are reagent compositions suitable for dispensing via a droplet-on-demand system.. ... Ventana Medical Systems Inc

Multiplex assay for improved scoring of tumor tissues stained for pd-l1

Multiplex assays for improved scoring of tumor tissues stained with pd-l1 featuring pd-l1 staining in a first color plus staining of one or more differentiating markers, such as a marker specific for tumor cells and a marker specific for immune cells, are disclosed. The differentiation between the tumor cells and immune cells may improve the ease of scoring, the accuracy and speed of scoring, and the reproducibility of scoring of pd-l1 positive samples for therapy purposes.. ... Ventana Medical Systems Inc

Anti-pd-l1 antibodies and diagnostic uses thereof

The invention provides programmed death-ligand 1 (pd-l1) antibodies and methods of using the same.. . ... Ventana Medical Systems Inc

System and method for image segmentation

An image segmentation method is disclosed that allows a user to select image component types, for example tissue types and or background, and have the method of the present invention segment the image according to the user's input utilizing the superpixel image feature data and spatial relationships.. . ... Ventana Medical Systems Inc

Systems and methods for area-of-interest detection using slide thumbnail images

The subject disclosure provides systems and methods for determination of area of interest (aoi) for different types of input slides. Slide thumbnails may be assigned into one of five different types, and separate algorithms for aoi detection executed depending on the slide type. ... Ventana Medical Systems Inc

Classifying nuclei in histology images

Disclosed, among other things, is a computer device and computer-implemented method of classifying cells within an image of a tissue sample comprising providing the image of the tissue sample as input; computing nuclear feature metrics from features of nuclei within the image; computing contextual information metrics based on nuclei of interest with the image; classifying the cells within the image using a combination of the nuclear feature metrics and contextual information metrics.. . ... Ventana Medical Systems Inc

Assay reaction controller magazine

Devices and methods for providing and dispensing opposables onto slides are provided in which magazines loaded with opposables include retention arms to reduce movement of the opposables during shipment and processing and to reduce or eliminate contamination.. . ... Ventana Medical Systems Inc

11/30/17 / #20170343556

Histochemical assay for evaluating expression of programmed death ligand 1 (pd-l1)

This disclosure relates to methods of assaying and scoring pd-l1 expression in tumors. Tumor samples are labeled with an antibody or antibody fragment that specifically binds to human pd-l1 and binding is detected. ... Ventana Medical Systems Inc

11/23/17 / #20170337695

Foreground segmentation and nucleus ranking for scoring dual ish images

The present disclosure describes a method of foreground segmentation and nucleus ranking for scoring dual ish images. The method has been developed to better identify those nuclei, within a selected field of view, that meet the criteria for dual ish scoring.. ... Ventana Medical Systems Inc

11/23/17 / #20170336363

Standardizing diffusion of a fluid into tissue

Disclosed are a system and method for evaluating a tissue sample that has been removed from a subject. Movement of fluid through the tissue sample is monitored by measuring time of flight of acoustic waves passed through the tissue sample. ... Ventana Medical Systems Inc

11/23/17 / #20170336303

Methods for tissue sample fixation using an extended soak in aldehyde-based solutions

An extended tissue fixation method is provided including at least one soak in a cold aldehyde-based fixative solution followed by a soak in a warm aldehyde-based fixative solution over a period greater than 2 days. Using the processes disclosed herein, improved tissue morphology and ihc staining as well as superior preservation of post-translation modification signals, e.g. ... Ventana Medical Systems Inc

11/09/17 / #20170323431

Quality metrics for automatic evaluation of dual ish images

The present disclosure is directed to a computer system designed to (i) receive a series of images as input; (ii) compute a number of metrics derived from focus features and color separation features within the images; and (iii) evaluate the metrics to return (a) an identification of the most suitable z-layer in a z-stack, given a series of z-layer images in a z-stack; and/or (b) an identification of those image tiles that are more suitable for cellular based scoring by a medical professional, given a series of image tiles from an area of interest of a whole slide scan.. . ... Ventana Medical Systems Inc

11/09/17 / #20170323148

Dot detection, color classification of dots and counting of color classified dots

The present disclosures relates to a method of detecting, classifying, and counting dots in an image of a tissue specimen comprising detecting dots in an image of the tissue sample that meet criteria for absorbance strength, black unmixed image channel strength, red unmixed image channel strength, and a difference of gaussian threshold, wherein the detected dots correspond to in situ hybridization signals in the tissue samples; classifying the detected dots as belonging to a black in situ hybridization signal or to a red in situ hybridization signal; and calculating a ratio of those dots belonging to the black in situ hybridization signal and those belonging to the red in situ hybridization signal.. . ... Ventana Medical Systems Inc

11/09/17 / #20170320054

Transporter systems, assemblies and associated methods for transporting tissue samples

A tissue sample that has been removed from a subject can be properly fixed for evaluation using the disclosed transporter assembly for carrying a tissue sample and method for fixing an unfixed tissue sample. In one embodiment, the disclosed assembly includes a transport container, a fixative in the transport container, and a cooling device that reduces and/or maintains the temperature of the fixative to perform a pre-soaking process at a temperature of less than about 7° c. ... Ventana Medical Systems Inc

10/26/17 / #20170309021

Systems and methods for co-expression analysis in immunoscore computation

Described herein are methods for co-expression analysis of multiple markers in a tissue sample comprising: computing a heat map of marker expression for each of a plurality of single marker channel images, wherein each of the plurality of single marker channel images comprise a single marker; identifying one or more candidate regions of interest in each heat map of marker expression; computing overlay masks comprising the identified one or more candidate regions of interest from each heat map of marker expression; determining one or more co-localized regions of interest from the overlay masks; mapping the one or more co-localized regions of interest to a same coordinate position in each of the plurality of single marker channel images; and estimating a number of cells in at least one of the determined one or more co-localized regions of interest in each of the plurality of single marker channel images.. . ... Ventana Medical Systems Inc

10/05/17 / #20170284969

Accurately calculating acoustic time-of-flight

The subject disclosure presents systems and computer-implemented methods for determining an acoustic time-of-flight (tof) of sound waves through a sample material with greater accuracy and in a more repeatable fashion, by invoking one or more of an envelope generation for an error function, fitting a non-linear curve to an ultrasound frequency sweep, or performing a clustered piece-wise linear regression on individual linear parts of the ultrasonic frequency sweep. The systems and methods are useful for, among other things, monitoring diffusion of fluids through porous materials, such as tissue samples.. ... Ventana Medical Systems Inc

10/05/17 / #20170284920

Diffusion monitoring protocol for optimized tissue fixation

The subject disclosure presents systems and computer-implemented methods for evaluating a tissue sample that has been removed from a subject. A change in speed of the energy traveling through the sample is evaluated to monitor changes in the biological sample during processing. ... Ventana Medical Systems Inc

10/05/17 / #20170284908

Autostainer hematoxylin and methods of use

This disclosure relates to hematoxylin staining formulations and particularly to formulations for use in autostainers. The disclosed compositions were discovered to possess atypical stability under storage while having high stain quality and sufficiently fast staining performance. ... Ventana Medical Systems Inc

10/05/17 / #20170284859

Obtaining true diffusivity constant

The subject disclosure presents systems and computer-implemented methods for calculating the diffusivity constant of a sample using acoustic time-of-flight (tof) based information correlated with a diffusion model to reconstruct a sample's diffusivity coefficient. Operations disclosed herein such as acoustically determining the phase differential accumulated through passive fluid exchange (i.e. ... Ventana Medical Systems Inc

09/21/17 / #20170270666

Computational pathology systems and methods for early-stage cancer prognosis

The subject disclosure presents systems and computer-implemented methods for providing reliable risk stratification for early-stage cancer patients by predicting a recurrence risk of the patient and to categorize the patient into a high or low risk group. A series of slides depicting serial sections of cancerous tissue are automatically analyzed by a digital pathology system, a score for the sections is calculated, and a cox proportional hazards regression model is used to stratify the patient into a low or high risk group. ... Ventana Medical Systems Inc

09/21/17 / #20170270346

Systems and methods for generating fields of view

Embodiments disclosed herein are directed, among other things, to imaging systems, methods, and apparatuses for automatically identifying fields of view (fovs) for regions in an image encompassing tumor are disclosed. In embodiments and in further aspects of the present invention, a computer-implemented method is disclosed for a tumor region based immune score computation. ... Ventana Medical Systems Inc

09/21/17 / #20170268068

Method for discrimination of metaplasias from neoplastic or preneoplastic lesions

The present invention relates to a method for discrimination of p16ink4a overexpressing metaplasias from neoplastic or preneoplastic p16ink4a overexpressing lesions by determination of the level of high risk hpv encoded gene-products such as e.g. Hpv e2 and/or hpv e7 molecules in biological samples in the course of cytological testing procedures. ... Ventana Medical Systems Inc

09/07/17 / #20170254813

Proximity assays using chemical ligation and hapten transfer

Methods for in situ detecting proximity of two targets of interest featuring an antibody conjugated with a cleavable bridge component having a detectable moiety and an antibody conjugated with a non-cleavable bridge component. The bridge components each have a chemical ligation group adapted to form a covalent bond under particular conditions and when the targets are in close proximity. ... Ventana Medical Systems Inc

08/24/17 / #20170243051

Image analysis system using context features

The present disclosure relates, among other things, to an image analysis method for identifying objects belonging to a particular objet class in a digital image of a biological sample. The method may include, among other things, analyzing the digital image for automatically or semi-automatically identifying objects in the digital image; analyzing the digital image for identifying, for each object, a first object feature value of a first object feature of said object; analyzing the digital image for computing one or more first context feature values; inputting both the first object feature value of each of the objects in the digital image and the first context feature value of said digital image into a first classifier; and executing the first classifier.. ... Ventana Medical Systems Inc

08/17/17 / #20170234886

Multiples immunohistochemical assay using primary antibodies of the same host species

Disclosed herein are methods and systems for detecting two different epitopes in the same sample using immunohistochemical methods using primary antibodies from the same host species and secondary antibodies immunoreactive with antibodies of the host species of the primary antibodies. Methods to denature and block the first primary antibody contacted with the sample are provided.. ... Ventana Medical Systems Inc

07/27/17 / #20170212122

Multiplex tp53/cen17/b cell gene-protein co-detection assay and uniquely specific probes for 19q12, insr, atm, dleu2, tp53, and 13q12

Disclosed herein are multiplex methods for co-detecting a b cell marker, tp53 nucleic acid, and chromosome 17 centromere dna in a single sample. Samples stained for the b cell marker (e.g., cd79a protein), tp53 nucleic acid, and chromosome 17 centromere dna may allow for the identification of the subtype of chronic lymphocytic leukemia (cll) with the 17p deletion. ... Ventana Medical Systems Inc

07/27/17 / #20170212019

Polymer stabilization of chromogen solutions

Disclosed embodiments concern a composition comprising dab chromogen, and/or derivative thereof, a stabilizer, and polymer capable of preventing or reducing dab precipitation relative to a composition that does not comprise the polymer. Also disclosed herein is a method for using the disclosed composition and embodiments of a kit.. ... Ventana Medical Systems Inc

07/20/17 / #20170206655

Systems and methods for color deconvolution

The present disclosure involves a computer-implemented unmixing algorithm that employs a least-square method involving image patches, and a computer-implemented unmixing or color deconvolution method that incorporates spatial smoothness and structure continuity constraints, for example, into a neighborhood graph regularizer, such as using a graph to enforce the pixel value similarities for those pixels in the same neighborhood.. . ... Ventana Medical Systems Inc

07/20/17 / #20170205416

Method of identifying treatment responsive non-small cell lung cancer using anaplastic lymphoma kinase (alk) as a marker

Disclosed herein are methods for identifying a subject as having nsclc that is predicted or is likely to respond to treatment with an alk inhibitor, for example crizotinib. The methods include identifying a sample including nsclc tumor cells as alk-positive or alk-negative using immunohistochemistry (ihc) and scoring methods disclosed herein. ... Ventana Medical Systems Inc

07/20/17 / #20170205399

Polymers and conjugates comprising the same

Polymers and conjugates comprising polymers are disclosed herein. In some embodiments, the conjugates disclosed are suitable for use as detection probes in immunohistochemical assays, including multiplex immunohistochemical assays.. ... Ventana Medical Systems Inc

06/29/17 / #20170184477

Compositions, methods, and systems for tissue fixation

The present disclosure relates to use of high-concentration aldehyde-based fixatives to fix tissue samples. Aldehyde concentrations are selected that significantly increase rate of diffusion of the fixative solution into the tissue. ... Ventana Medical Systems Inc

06/15/17 / #20170169567

Systems and methods for detection of structures and/or patterns in images

The subject disclosure presents systems and computer-implemented methods for automatic immune cell detection that is of assistance in clinical immune profile studies. The automatic immune cell detection method involves retrieving a plurality of image channels from a multi-channel image such as an rgb image or biologically meaningful unmixed image. ... Ventana Medical Systems Inc

06/01/17 / #20170152573

Single-stranded oligonucleotide probes for chromosome or gene copy enumeration

Single-stranded oligonucleotide probes, systems, kits and methods for chromosome enumeration, gene copy enumeration, or tissue diagnostics. The probes are particularly suited for detecting gene amplification, deletion, or rearrangement in tissue samples in a single, dual, or multiplexed assay. ... Ventana Medical Systems Inc

05/18/17 / #20170140246

Automatic glandular and tubule detection in histological grading of breast cancer

Methods, systems, and apparatuses for automatically identifying glandular regions and tubule regions in a breast tissue sample are provided. An image of breast tissue is analyzed to detect nuclei and lumen candidates, identify tumor nuclei and true lumen from the candidates, and group tumor nuclei with neighboring tumor nuclei and lumina to define tubule glandular regions and non-tubule glandular regions of the image. ... Ventana Medical Systems Inc

05/11/17 / #20170131303

Automated high volume slide processing system

An automated system is provided for performing slide processing operations on slides bearing biological samples. In one embodiment, the disclosed system includes a slide tray holding a plurality of slides in a substantially horizontal position and a workstation that receives the slide tray. ... Ventana Medical Systems Inc

05/11/17 / #20170131271

Antibody-nanoparticle conjugates and methods for making and using such conjugates

Disclosed herein are antibody-nanoparticle conjugates that include two or more nanoparticles (such as gold, palladium, platinum, silver, copper, nickel, cobalt, iridium, or an alloy of two or more thereof) directly linked to an antibody or fragment thereof through a metal-thiol bond. Methods of making the antibody-nanoparticle conjugates disclosed herein include reacting an arylphosphine-nanoparticle composite with a reduced antibody to produce an antibody-nanoparticle conjugate. ... Ventana Medical Systems Inc

05/04/17 / #20170122971

Opposables and automated specimen processing systems with opposables

A specimen processing system is capable of processing specimens carried on slides. The specimen processing system can sequentially deliver slides and opposables to specimen processing stations. ... Ventana Medical Systems Inc

04/27/17 / #20170115476

Automated coverslipper and methods of use

An apparatus and method for selecting and dispensing coverglasses over specimens on slides for the purpose of viewing specimens through a microscope. The selecting device contains suctioning mechanisms for picking up a coverglass from a stack of coverglasses. ... Ventana Medical Systems Inc

04/13/17 / #20170103521

Medical image analysis for identifying biomarker-positive tumor cells

A method for identifying biomarker-positive tumor cells is disclosed. The method includes, for example, reading a first digital image and a second digital image into memory, the first and second digital image depicting the same area of a first slide; identifying a plurality of nuclei and positional information of said nuclei by analyzing the light intensities in the first digital image; identifying cell membranes which comprise the biomarker by analyzing the light intensities in the second digital image and by analyzing the positional information of the identified nuclei; and identifying biomarker-positive tumor cells in said area, wherein a biomarker-positive tumor cell is a combination of one identified nucleus and one identified cell membrane that surrounds the identified nucleus.. ... Ventana Medical Systems Inc

04/06/17 / #20170098310

Edge-based local adaptive thresholding system and methods for foreground detection

Systems and methods for generating a locally adaptive threshold image for foreground detection performing operations including creating a saliency edge strength image or layer indicating edge or border pixels of the nuclei by performing tensor voting on pixels neighboring the initial edge pixels within an image region to refine true edges are featured. Further, for each of a plurality of regions or blocks of the image, an adaptive threshold image is determined by sampling a foreground pixel and a background pixel for each initial edge pixel or refined edge pixel, generating histograms for both background and foreground saliency (or gradient magnitude) modulated histograms, determining a threshold range for each block of the image, and interpolating the threshold at each pixel based on the threshold range at each block. ... Ventana Medical Systems Inc

04/06/17 / #20170097369

Automated specimen processing systems and methods of detecting specimen-bearing microscope slides

Systems and methods that enable automated processing of specimens carried on microscope slides are described herein. In some embodiments, the system can include, for example, a slide ejector assembly having a slide staging device configured to receive a slide and an over-travel inhibitor that includes a first vacuum port positioned to draw a first vacuum between the slide and a standby platform as the slide is moved across at least a portion of the standby platform. ... Ventana Medical Systems Inc

04/06/17 / #20170097289

Specimen processing systems, pipette assemblies and methods for preparing reagents

Systems and methods that enable automated processing of specimens carried on microscope slides are described herein. Aspects of the technology are directed, for example, to automated slide processing apparatuses capable of dispensing liquids onto microscope slides. ... Ventana Medical Systems Inc

04/06/17 / #20170097288

Automated specimen processing systems and methods

The disclosure presents systems and methods for processing a specimen slide using a specimen processing system. Specimen slides may sequentially be ejected from a slide carrier towards a label reader to determine an appropriate processing protocol for the slides. ... Ventana Medical Systems Inc

04/06/17 / #20170096487

Antibodies specifically binding to her3

The present invention relates to isolated antibodies, or an antigen portions thereof, which bind to human her3. The novel antibodies are of great utility since they allow for the sensitive and specific detection of human her3. ... Ventana Medical Systems Inc

03/30/17 / #20170089911

Quinone methide analog signal amplification

Disclosed herein are novel quinone methide analog precursors and embodiments of a method and a kit of using the same for detecting one or more targets in a biological sample. The method of detection comprises contacting the sample with a detection probe, then contacting the sample with a labeling conjugate that comprises an enzyme. ... Ventana Medical Systems Inc

03/23/17 / #20170082627

Significance of intratumoral her2 heterogeniety in breast cancer and uses therefore

Disclosed herein are methods for predicting the response to a her2-directed therapy and for scoring a breast cancer tumor sample. In some embodiments, the methods include contacting the sample with an antibody that specifically binds her2 protein and detecting presence and/or amount of her2 protein and contacting the sample with a nucleic acid probe that specifically binds to her2 genomic dna and detecting presence and/or amount of her2 genomic dna (such as her2 gene copy number). ... Ventana Medical Systems Inc

02/23/17 / #20170053397

Systems and methods for spectral unmixing of microscopic images using pixel grouping

Systems and methods for speeding up a spectral unmixing process by using pixel groups are disclosed. Operations including forming groups of similar pixels, and unmixing only one representative pixel from each pixel group enable determination of an unmixing result for all the pixels in the group. ... Ventana Medical Systems Inc

02/16/17 / #a process for removing hematoxylin precipitate from a surface of an automated hematoxylin stainer, systems adapted for performing such processes. the process and systems use a hematein precipitate removal solution having a ph in the range of between about 8.9 and 10.5 and including a liquid oxidizing component and alkaline component.

Ventana Medical Systems, Inc.

. . ... Ventana Medical Systems Inc

02/02/17 / #20170030810

Automated lean methods in anatomical pathology

An embodiment of the method of the invention is a method of automating information flow in a laboratory performing tissue staining comprising positioning a networked label printer adjacent to a cutting station, the printer configured to access patient data directly or indirectly from the hospital lis, the printer being configured with a data element scanner in electronic communication with said printer; inputting data from a tissue cassette-associated data element at said printer, whereby inputting data comprises reading the data from the cassette-associated data element and uploading the cassette data to the lis; identifying the corresponding test protocol identifier and then downloading the test protocol data to the printer; printing information on labels corresponding to each test specified in the lis for the patient; attaching a single label to each slide; and cutting a tissue section for each labeled slide and mounting the section on the slide.. . ... Ventana Medical Systems Inc

02/02/17 / #20170029877

Polytag probes

The present invention provides probes and probe systems for detection of nucleic acids, and in particular probes and probe systems comprising target nucleic acid probes which comprise a plurality of detection sequences and detection nucleic acid probes which hybridize to the detection sequences of the target nucleic acid probes and which further comprise a plurality of detectable moieties, such as haptens.. . ... Ventana Medical Systems Inc

01/26/17 / #20170023579

Multiplex her2 and estrogen receptor co-staining assays for detecting tumor heterogeneity

Disclosed herein are methods for detecting the presence and/or amount of her2 protein, her2 nucleic acid (for example, her2 genomic dna), er protein, and chromosome 17 centromere dna in a single sample. Samples stained for her2 protein, her2 dna, er protein, and chromosome 17 dna allow for the identification of various types of cancer cells, for example her2 protein positive/er protein positive/her2 gene positive cells, her2 protein positive/er protein negative/her2 gene positive cells, her2 protein negative/er protein positive/her2 gene positive cells, and her2 protein negative/er protein negative/her2 gene positive cells.. ... Ventana Medical Systems Inc

01/26/17 / #20170023450

Apparatus and method for biological sample processing

An apparatus and method are described that achieve independent and simultaneous processing of a plurality of substrate-supported biological samples. In one embodiment, substrate holders arranged in a minor arc are independently moveable between a processing position and an access position, and reagents are delivered to substrates held in the substrate holders through a nozzle plate that moves along the arc of substrate holders. ... Ventana Medical Systems Inc

01/12/17 / #20170010194

Automated specimen processing systems and multistep processing of microscope slides

Systems and methods that enable automated processing of specimens carried on microscope slides are described herein. Aspects of the technology are directed, for example, to automated specimen processing systems and methods for dispensing liquids onto slides. ... Ventana Medical Systems Inc

01/12/17 / #20170009305

Single-stranded oligonucleotide probes for chromosome or gene copy enumeration

Single-stranded oligonucleotide probes, systems, kits and methods for chromosome enumeration, gene copy enumeration, or tissue diagnostics. The probes are particularly suited for detecting gene amplification, deletion, or rearrangement in tissue samples in a single, dual, or multiplexed assay. ... Ventana Medical Systems Inc








ARCHIVE: New 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009



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