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Zogenix Inc patents


Recent patent applications related to Zogenix Inc. Zogenix Inc is listed as an Agent/Assignee. Note: Zogenix Inc may have other listings under different names/spellings. We're not affiliated with Zogenix Inc, we're just tracking patents.

ARCHIVE: New 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 | Company Directory "Z" | Zogenix Inc-related inventors


Fenfluramine compositions and methods of preparing the same

Methods of preparing a fenfluramine active pharmaceutical ingredient are provided. Aspects of the method include (a) hydrolyzing a 2-(3-(trifluoromethyl)phenyl)acetonitrile composition to produce a 2-(3-(trifluoromethyl)phenyl)acetic acid composition; (b) reacting the 2-(3-(trifluoromethyl)phenyl)acetic acid composition with acetic anhydride and a catalyst to produce a 1-(3-(trifluoromethyl)phenyl)propan-2-one composition; and (c) reductively aminating the 1-(3-(trifluoromethyl)phenyl)propan-2-one composition with ethylamine using a borohydride reducing agent to produce a fenfluramine composition. ... Zogenix Inc

Compositions and methods for treating seizure disorders

Functional analogs of fenfluramine are provided. The subject fenfluramine functional analogs find use in the treatment of a variety of diseases. ... Zogenix Inc

Formulation for inhibiting formation of 5-ht2b agonists and methods of using same

Drug combinations and their use are disclosed. A first drug is administered in combination with a second drug. ... Zogenix Inc

Metabolism resistant fenfluramine analogs and methods of using the same

Metabolism-resistant fenfluramine analogs are provided. The subject fenfluramine analogs find use in the treatment of a variety of diseases. ... Zogenix Inc

Fenfluramine compositions and methods of preparing the same

Methods of preparing a fenfluramine active pharmaceutical ingredient are provided. Aspects of the method include (a) hydrolyzing a 2-(3-(trifluoromethyl)phenyl)acetonitrile composition to produce a 2-(3-(trifluoromethyl)phenyl)acetic acid composition; (b) reacting the 2-(3-(trifluoromethyl)phenyl)acetic acid composition with acetic anhydride and a catalyst to produce a 1-(3-(trifluoromethyl)phenyl)propan-2-one composition; and (c) reductively aminating the 1-(3-(trifluoromethyl)phenyl)propan-2-one composition with ethylamine using a borohydride reducing agent to produce a fenfluramine composition. ... Zogenix Inc

Combination treatment of specific forms of epilepsy

Formulations for and methods of treatment of dravet syndrome that avoid side effects are disclosed. The formulations comprise a 5-ht receptor agonists which does not agonize selected 5-ht receptor subtypes, and in particular does not agonize the receptor subtype 5-ht2b. ... Zogenix Inc

Piston closures for drug delivery capsules

A drug capsule and a method for making a drug capsule for a drug delivery device, such as an auto injector or needle-free injector, with improved stability and container closure integrity. The injector comprises a drug capsule sealed by a piston fabricated from ptfe modified by the inclusion of a co-polymer of ppve, preferably in an amount less than 1% by weight, resulting in better performance while the device is stored and subjected to temperature cycling.. ... Zogenix Inc

Methods of treating lennox-gastaut syndrome using fenfluramine

A method of treating and/or preventing symptoms of lennox-gastaut syndrome (lgs) also known as lennox syndrome in a patient such as a patient previously diagnosed with lennox syndrome, by administering an effective dose of fenfluramine or its pharmaceutically acceptable salt to that patient. Lennox syndrome patients are treated at a preferred dose of less than about 2.0 to about 0.01 mg/kg/day.. ... Zogenix Inc








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