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Ab Science patents


Recent patent applications related to Ab Science. Ab Science is listed as an Agent/Assignee. Note: Ab Science may have other listings under different names/spellings. We're not affiliated with Ab Science, we're just tracking patents.

ARCHIVE: New 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 | Company Directory "A" | Ab Science-related inventors


Diazaspiroalkaneone-substituted oxazole derivatives as spleen tyrosine kinase inhibitors

The present invention is concerned with substituted oxazole derivatives that selectively modulate, regulate, and/or inhibit signal transduction mediated by certain native and/or mutant protein kinases implicated in a variety of human and animal diseases such as cell proliferative, metabolic, autoimmune, allergic, and degenerative disorders. In particular, the presently disclosed compounds are syk inhibitors.. ... Ab Science

Use of masitinib for treatment of an amyotrophic lateral sclerosis patient subpopulation

Disclosed is a method for treating patients afflicted with non-aggressive or moderately aggressive amyotrophic lateral sclerosis (als) whose rate of change of the revised amyotrophic lateral sclerosis functional rating scale (alsfrs-r) prior to treatment initiation is <1.1 points per month, the method including administering a tyrosine kinase inhibitor or mast cell inhibitor, in particular masitinib, or a pharmaceutically acceptable salt or solvate thereof, optionally in combination with at least one pharmaceutically active ingredient.. . ... Ab Science

Masitinib combination for use in treating breast cancer

. . Disclosed is a method for treating breast cancer in a subject in need thereof, including administering to the subject a therapeutically effective amount of a tyrosine kinase inhibitor or a pharmaceutically acceptable salt or solvate thereof, optionally in combination with a therapeutically effective amount of a chemotherapeutic agent.. . ... Ab Science

Use of an inhibitor of kinase activity, particularly masitinib, for treatment of prostate cancer

A treatment of patients afflicted with prostate cancer, wherein the treatment includes administering to a mammal in need thereof at least one tyrosine kinase inhibitor or mast cell inhibitor that is an inhibitor of kinase activity selected from the tyrosine kinases of: c-kit, pdgfr, lyn, fyn, or any combination thereof, in particular masitinib, optionally in combination with at least one pharmaceutically active ingredient.. . ... Ab Science

Use of masitinib for the treatment of progressive supranuclear palsy

A mast cell inhibitor, a pharmaceutical composition and a method for treating patients afflicted with progressive supranuclear palsy (psp), wherein the patients are treated with a tyrosine kinase inhibitor, c-kit inhibitor or mast cell inhibitor, in particular masitinib or a pharmaceutically acceptable salt or solvate thereof, optionally in combination with at least one pharmaceutically active ingredient.. . ... Ab Science

Use of masitinib for the treatment of crohn's disease

A method for treating patients afflicted with crohn's disease, wherein the patients are treated with a tyrosine kinase inhibitor, mast cell inhibitor or c-kit inhibitor, in particular masitinib, optionally in combination with at least one pharmaceutically active ingredient for treatment of crohn's disease.. . ... Ab Science








ARCHIVE: New 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009



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