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Academia Sinica patents


Recent patent applications related to Academia Sinica. Academia Sinica is listed as an Agent/Assignee. Note: Academia Sinica may have other listings under different names/spellings. We're not affiliated with Academia Sinica, we're just tracking patents.

ARCHIVE: New 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 | Company Directory "A" | Academia Sinica-related inventors


Plasmid, transformed plant cell and transgenic plant comprising the same, and methods for preparing a transgenic plant and for increasing yield of a plant under abiotic stresses

A method for increasing yield of a plant, and particularly a method for increasing yield of a plant under abiotic stresses. The method includes preventing or reducing antagonism of snf1 protein kinase (snrk1a) by a protein encoded by seq id no: 2 or seq id no: 4.. ... Academia Sinica

Compositions and methods relating to universal glycoforms for enhanced antibody efficacy

The present disclosure relates to compositions and methods of use comprising antibodies or binding fragments thereof further comprising universal fc glycoforms.. . ... Academia Sinica

Core constructs and their uses in configuring pharmaceutical molecules

The present disclosure provides various core constructs. According to embodiments of the present disclosure, the core construct can be used to configure pharmaceutical molecules. ... Academia Sinica

Apparatus and method for enhancing figure of merit in composite thermoelectric materials with aerogel

At least one of the present embodiments generally relates to an apparatus and a method for enhancing the figure of merit (zt) in composite thermoelectric materials using aerogel such as e.g., silicate/silica aerogel, carbon aerogel, chalcogenide aerogel and metal oxide aerogel. For example, the present embodiments provide apparatuses and methods for the addition of aerogels to two commonly used p and n type thermoelectric materials and thereby enhancing their thermoelectric figure of merits to record levels.. ... Academia Sinica

Antagonists for interleukin-17 receptor b (il-17rb) and its ligand il-17b for cancer therapy

Methods and compositions for treatment and therapy of cancer are provided. Specifically, antagonists specific for interleukin-17 receptor b (il-17rb) and its ligand il-17b are provided. ... Academia Sinica

Novel glucagon-like peptide 1 modulator and uses thereof

Disclosed herein are novel glucagon-like peptide-1 (glp-1) modulators and their uses in manufacturing medicaments for the treatment and/or prophylaxis of diseases and/or disorders associated with hyperglycemia.. . ... Academia Sinica

Human inkt cell activation using glycolipids

Glycosphingolipids (gsls) compositions and methods for inkt-independent induction of chemokines are disclosed.. . ... Academia Sinica

Transgenic plants expressing type 2c protein phosphatase abscisic acid (pp2caba) proteins and uses thereof

The present disclosure relates to transgenic plants that over-express pp2caba and methods of using such for enhancing osmotic stress tolerance.. . ... Academia Sinica

Broadband meta-optical device

The present invention provides an optical component comprising a dielectric layer and a nanorod array; the nanorod array is formed on a surface of the dielectric layer and extends along a lateral direction and a vertical direction. The nanorod array comprises a plurality of nanorods extending along the dielectric layer. ... Academia Sinica

Anti-vegfr2 human antibody for anti-angiogenic and targeted cancer therapy

An isolated antibody or an antigen-binding fragment thereof having a specific binding affinity to an epitope located within the domain 1 or domain 3 of human vascular endothelial growth factor receptor 2 (vegfr2; seq id no: 74) is disclosed. The epitope within the domain 3 of the vegfr2 is located between amino acid residues 250 and 270 of seq id no: 74. ... Academia Sinica

Alkynyl sugar analogs for labeling and visualization of glycoconjugates in cells

Methods for metabolic oligosaccharide engineering that incorporates derivatized alkyne-bearing sugar analogs as “tags” into cellular glycoconjugates are disclosed. Alkynyl derivatized fuc and alkynyl derivatized mannac sugars are incorporated into cellular glycoconjugates. ... Academia Sinica

A therapeutic gene cocktail for heart regeneration

A combination of active agents selected from a foxm1 enhancer, an id1 enhancer, and a jnk3 inhibitor and the uses thereof in promoting cardiomyocyte proliferation and treating heart diseases in a subject in need of the treatment.. . ... Academia Sinica

Platelet-like proteo-microparticles and method of using such in drug delivery

Proteo-microparticles such as proteoliposomes comprising a microparticle (e.g., a liposome) and platelet membrane proteins, wherein the proteo-microparticles are capable of binding to monocytes, neutrophils, or other circulating blood cells capable of migrating to an injured site. Also provided herein are uses of the proteoliposomes for delivering a therapeutic agent via monocytes to an injured site.. ... Academia Sinica

Methods for enhancing maturation of cardiomyocytes

Methods for promoting maturation of cardiomyocytes, involving introducing a microrna combination containing mir-125b, mir-199a, mir-221, and/or mir222, or suppression of erbb4 in immature cardiomyocytes, which may be co-cultured with endothelial cells.. . ... Academia Sinica

03/08/18 / #20180067992

Divide-and-conquer global alignment algorithm for finding highly similar candidates of a sequence in database

A divide-and-conquer global alignment algorithm for finding highly similar candidates of a sequence in database is disclosed. The invention gives a divide-and-conquer algorithm called kart, that separates the given sequence into smaller pieces whose alignment can be carried out independently, and their concatenated alignment constitutes the global alignment of the entire sequence. ... Academia Sinica

03/01/18 / #20180057804

Endoglycosidase mutants for glycoprotein remodeling and methods of using it

A mutant of endos2 includes one or more mutations in the sequence of a wild-type endos2 (seq id no: 1), wherein the one or more mutations are in a peptide region located within residues 133-143, residues 177-182, residues 184-189, residues 221-231, and/or residues 227-237, wherein the mutant of endos2 has a low hydrolyzing activity and a high tranglycosylation activity, as compared to those of the wild-type endos2. A method for preparing an engineered glycoprotein using the mutant of endos2 includes coupling an activated oligosaccharide to a glycoprotein acceptor. ... Academia Sinica

03/01/18 / #20180055887

Method for preparing induced mesenchymal stem cells and improving mesenchymal stem cell's characters and its applications

The present invention generally relates to a method for preparing induced mesenchymal stem cells (imscs) and its applications. The imscs, like mscs, can differentiate into multiple lineages, which may be beneficial for disease treatments. ... Academia Sinica

02/15/18 / #20180044437

Anti-inflammatory molecules with tissue-targeting functions

The present disclosure provides various molecular constructs having a targeting element and an effector element. Methods for treating osteoporosis using such molecular constructs are also disclosed.. ... Academia Sinica

02/15/18 / #20180042977

Development of a standardized and effect-optimized herbal extract of wedelia chinensis and its use for treating disease

A method for preparing a standardized wedelia chinensis extract and an extract prepared by the method. Also provided is a method for qualifying the standardized extract by characterizing its most abundant compounds and its biological activity in vitro. ... Academia Sinica

02/01/18 / #20180030473

Mutated nucleotide molecule, and transformed plant cells and plants comprising the same

The present invention relates to a method for producing male sterile plant, a mutated nucleotide molecule comprising a nucleotide sequence of the transcription factor bhlh142 and an inserted t-dna segment, and a novel transformed plant cell and a male-sterile mutant plant comprising the mutated nucleotide molecule, in which the transcription factor bhlh142 is not expressed. The present invention also relates to a novel reversible male sterile transgenic plant, wherein the transcription factor bhlh142 is overexpressed, and its preparation method. ... Academia Sinica

02/01/18 / #20180030097

Epitope-substituted vaccine for use in improving safety and immunogenicity against dengue viruses

Isolated mutant dengue virus e protein variants are disclosed. The variant comprises an amino acid sequence that is at least 80% identical to seq id no: 1 and has one or more amino acid residue substitutions at position corresponding to asn8 (n8), arg9 (r9), val12 (v12) and/or glu13 (e13). ... Academia Sinica

01/25/18 / #20180025108

Computational method for predicting functional sites of biological molecules

In a general aspect, a method for inferring one or more biomolecule-to-biomolecule interaction sites includes receiving data representative of a plurality of prediction models. Each prediction model is associated with a different atom type of a plurality of atom types and characterizes biomolecule-to-biomolecule interaction site specific patterns common to a plurality of three dimensional probability density maps. ... Academia Sinica

01/25/18 / #20180021460

Probes and methods for detecting amyloidogenic proteins

Disclosed herein are novel photocontrollable probes and methods for detecting aggregated forms of amyloidogenic proteins in cells, tissues, or organs of a live subject. Results of such detection may be useful for making prognosis on the subject whether he/she suffers from a neurodegenerative disease and/or diabetes mellitus.. ... Academia Sinica

01/11/18 / #20180011104

Reactive labelling compounds and uses thereof

Provided are azido-bodipy compounds of formula (i), cyclooctyne-based fluorogenic probes of formula (iv), and activity-based probes of formula (vi). These compounds undergo azide-alkyne cycloadditions (aac) with to form triazolyl products. ... Academia Sinica

01/11/18 / #20180009877

A phage-displayed single-chain variable fragment library

Disclosed herein is a phage-displayed single-chain variable fragment (scfv) library, that comprised a plurality of phage-displayed scfvs characterized with (1) a specific cs combination; (2) a specific distribution of aromatic residues in each cdr; and (3) a specific sequence in each cdr. The present scfv library could be used to efficiently produce different antibodies with binding affinity to different antigens. ... Academia Sinica

12/21/17 / #20170362265

Methods for modular synthesis of n-glycans and arrays thereof

The present disclosure relates to novel modular methods for generating a diversity of n-glycans of high mannose, hybrid and complex types. The present disclosure also relates to exemplary arrays of the synthesized n-glycans spotted onto aluminium oxide coated slides. ... Academia Sinica

12/21/17 / #20170360924

Human inkt cell activation using glycolipids with altered glycosyl groups

Glycosphingolipids (gsls) bearing α-glucose (α-glc) that preferentially stimulate human invariant nkt (inkt) cells are provided. Gsls with α-glucose (α-glc) that exhibit stronger induction in humans (but weaker in mice) of cytokines and chemokines and expansion and/or activation of immune cells than those with α-galactose (α-gal) are disclosed. ... Academia Sinica

12/21/17 / #20170360884

Method for treating influenza a virus infection

Disclosed herein is a method of treating influenza a virus (iav) infection by a fusion protein. According to some embodiments of the present disclosure, the fusion protein comprises a hbd peptide and a igg1 fc region. ... Academia Sinica

12/21/17 / #20170360863

Use of polyacetylenic glycosides for suppression of granulocytic myeloid-derived suppressor cell activities and tumor metastasis

A pharmacological composition for use in inhibiting differentiation, functional activities, and population of granulo-cytic myeloid-derived suppressor cells (gmdscs) and/or suppressing, tumor metastasis in a subject in need thereof is disclosed. The composition comprises a therapeutically effective amount of bidens pilosa extract, or more than one polyacetylenic compounds purified or isolated from the b. ... Academia Sinica

12/14/17 / #20170355750

High-throughput screening of functional antibody fragments, immunoconjugate comprising the same, and adaptor-drug conjugate for screening

Disclosed herein are methods for high-throughput screening of a functional antibody fragment for an immunoconjugate that targets a protein antigen. The method combines a phage-displayed synthetic antibody library and high-throughput cytotoxicity screening of non-covalently assembled immunotoxins or cytotoxic drug to identify highly functional synthetic antibody fragments for delivering toxin payloads.. ... Academia Sinica

11/30/17 / #20170340700

Use of an antimicrobial peptide tp4 in treating a cancer

The preset invention relates to a new approach for treating a cancer, particularly a malignant tumor, a multidrug-resistant (mdr) cancer, a recurrent cancer or a metastatic cancer, using a specific cationic antimicrobial peptide (cap), tilapia piscidin 4 (tp4), which is derived from nile tilapia (oreochromis niloticus). Also provided is a method for treating a breast cancer, particularly triple negative breast cancer (tnbc) with tp4.. ... Academia Sinica

11/23/17 / #20170332645

Plant defense signaling peptides and applications thereof

The present invention relates to a novel plant defense signaling peptide and applications thereof.. . ... Academia Sinica

10/12/17 / #20170290886

Treatment of neurodevelopmental disorders

Disclosed herein are methods for treating a neurodevelopmental disorder in a subject in need thereof. The method includes administering to the subject in need thereof an effective amount of a methyl-cpg-binding protein 2 (mecp2) or a nucleic acid encoding the mecp2 to alleviate or ameliorate the symptoms associated with the neurodevelopmental disorder. ... Academia Sinica

10/12/17 / #20170290820

Methods and compositions for treating beta-thalassemia and sickle cell disease

Compounds, pharmaceutical compositions, and methods for treating anemia β-thalassemia anemia or sickle cell anemia.. . ... Academia Sinica

10/05/17 / #20170283878

Modulation of globoseries glycosphingolipid synthesis and cancer biomarkers

The present disclosure relates to methods and compositions which can modulate the globoseries glycosphingolipid synthesis. Particularly, the present disclosure is directed to glycoenzyme inhibitor compound and compositions and methods of use thereof that can modulate the synthesis of globoseries glycosphingolipid ssea-3/ssea-4/globoh in the biosynthetic pathway; particularly, the glycoenzyme inhibitors target the alpha-4galt; beta-4galnact-i; or beta-3galt-v enzymes in the globoseries synthetic pathway. ... Academia Sinica

10/05/17 / #20170283793

Dna sequence and a mutator insertion sequence for increasing mutation rate

The invention relates to a dna sequence for increase of a mutation rate over a specific region of dna. Particularly, the invention provides a unique guanine nucleotide sequence and a mutator insertion sequence incorporated with the guanine nucleotide sequence and their applications in increasing a mutation rate.. ... Academia Sinica

10/05/17 / #20170283493

Methods for enhancing permeability to blood-brain barrier, and uses thereof

Disclosed herein is a method of facilitating the delivery of an agent across blood-brain barrier (bbb) of a subject. The method includes administering to the subject in sequence or concomitantly, an effective amount of a growth factor selected from the group consisting of, vascular endothelial growth factor (vegf), insulin-like growth factor i (igf-1), igf-ii, a portion thereof and a combination thereof; and an agent that is any of a therapeutic agent or an imaging agent. ... Academia Sinica

10/05/17 / #20170283477

Animal model of longevity and related methods for increasing longevity and inhibiting tumorigenesis

The present invention includes a genetically-modified non-human animal model of longevity and increased health span, which is associated with reduced tumorigenesis and tumor metastasis, as well as related methods for increasing longevity and health span, reducing tumorigenesis and tumor metastasis, and identifying active agents that confer increased longevity or health span, or reduced tumorigenesis or tumor metastasis.. . ... Academia Sinica

09/28/17 / #20170275389

Novel glycan conjugates and use thereof

This disclosure includes an immunogenic composition containing (a) a glycan conjugate including a carrier and one or more glycans, wherein each of the one or more glycans is conjugated with the carrier through a linker, and optionally (b) an adjuvant. The one or more glycan is each a globo h derivative.. ... Academia Sinica

08/24/17 / #20170239282

Bidens pilosa and polyacetylenic compounds for prevention and treatment of coccidiosis

A composition for use in prevention, inhibition and/or treatment of coccidiosis in an animal is disclosed. The composition comprises an effective amount of bidens pilosa, an active constituent thereof, or an active compound isolated therefrom. ... Academia Sinica

08/17/17 / #20170233658

Batch-process supertorrefaction system and method

A compact, transportable batch-process supertorrefaction system includes at least one supertorrefying unit, a liquid tank containing molten salt, and a wash tank including a plurality of basins containing water having different temperatures and different salinity. The liquid tank and the wash tank sequentially supply the molten salt and the water to a receiving space of the at least one supertorrefying unit to supertorrefy the biomass into charcoal and to rinse and cool the charcoal, respectively. ... Academia Sinica

08/10/17 / #20170229703

Method of preparation a battery electrode by spray coating, an electrode and a battery made by method thereof

The present invention provides a method of preparing a battery electrode, comprising: (a) providing electroactive particles; (b) mixing the electroactive particles with a graphene-based material to form a composite; and (c) spray coating the composite onto a substrate to form the battery electrode; wherein the percentage of the electroactive particles to the graphene-based material is 40-95 wt %. Furthermore, the present invention provides a high performance battery electrode and lithium sulfur battery or lithium metal oxide-sulfur battery.. ... Academia Sinica

08/10/17 / #20170226169

Bipartite molecules and uses thereof in treating diseases associated with abnormal protein aggregates

Bipartite molecules comprising a peptide affinity moiety and at least one charged moiety and uses thereof in reducing formation of abnormal protein aggregate and treating diseases associated with such abnormal protein aggregate, including neurodegenerative disease characterized by formation of protein aggregates.. . ... Academia Sinica

08/10/17 / #20170224716

Methods and compositions for treating pain

The invention provides a new use of adenosine analogs for the treatment of pain through activation of neurokinin 1 (nk1) receptor signaling pathway, thereby inducing the activation of activation of m-type potassium channel to induce outward currents. A method and pharmaceutical composition for treating pain comprising an adenonsine analog that activates nk1 receptor signaling, thereby inducing outward current are also provided.. ... Academia Sinica

08/03/17 / #20170219593

Methods and systems for cancer diagnosis and prognosis

The disclosure provides for compositions and methods of making and using a foam composition and its utility in clinical applications.. . ... Academia Sinica

07/27/17 / #20170215041

Building design information based indoor positioning system

An indoor positioning system based on building design information is disclosed. The system includes a server computer to provide indoor position information relating to a building, a plurality of beacons to be installed in selected locations in the building and to broadcast by each beacon an indoor position message indicating the indoor position of the beacon, and an installer to configure the beacons with their corresponding indoor position information. ... Academia Sinica

07/13/17 / #20170199184

Capture, purification, and release of biological substances using a surface coating

This invention relates to a surface coating for capture circulating rare cells, comprising a nonfouling composition to prevent the binding of non-specific cells and adsorption of serum components; a bioactive composition for binding the biological substance, such as circulating tumor cells; with or without a linker composition that binds the nonfouling and bioactive compositions. The invention also provide a surface coating for capture and purification of a biological substance, comprising a releasable composition to release the non-specific cells and other serum components; a bioactive composition for binding the biological substance, such as circulating tumor cells; with or without a linker composition that binds the releasable and bioactive compositions. ... Academia Sinica

06/29/17 / #20170183660

Aptamer targeting mage-a3 peptide and uses thereof

Disclosed herein is an aptamer targeting a mhc-presented peptide and its uses thereof. The mhc-presented peptide is expressed in various cancer cells; therefor, the aptamer of the disclosure is useful as a bio-tool to label and/or treat peptide-presenting cancer cells. ... Academia Sinica

06/29/17 / #20170182001

Novel sesquiterpene derivatives and their use in inflammation or cancer treatment

A new class of sesquiterpene derivative useful for treating cancerous and inflammatory diseases are disclosed. These deoxyelephantopin derivatives are effective in suppressing proliferation, migration, mobility, invasion, growth, and/or metastasis of cancer cells in a patient, or useful for enhancing an anti-proliferative effect of another anti-cancer drug on cancer cells when treating a patient, or for sensitizing and/or enhancing an anti-cancer effect of a gluthathione synthesis blocker on inhibition of triple negative breast cancer cell activity, or for treatment and/or prophylaxis of lipopolysaccharide-stimulated inflammatory response in a patient, or for all of the above. ... Academia Sinica

06/22/17 / #20170173154

Multi-drug delivery system and use thereof

Disclosed herein is a multiple drugs delivery system and its uses in treating diseases. The multiple drugs delivery system includes, an anti-peg antibody for directing the pegylated therapeutic to the treatment site; and a hydrogel for retaining the anti-peg antibody and/or the pegylated therapeutic at the treatment site for at least 3 days. ... Academia Sinica

06/08/17 / #20170159051

Small interfering rna and pharmaceutical composition and method for inhibiting galectin-12 expression and/or enhancing lipolysis containing the same

A small interfering rna is provided. The small interfering rna consists of a passenger strand and a guide strand, wherein the sequence of the passenger strand comprises the sequence of seq id no. ... Academia Sinica

06/01/17 / #20170153250

Diagnosis and treatment of kawasaki disease

Described is a method of diagnosing, treating, or monitoring a treatment for kawasaki disease in a subject. The method includes detecting the level of a biomarker in a sample obtained from the subject, the biomarker being il-7f, scd40l, mpif-1, e-selectin, ip-10, or il-33. ... Academia Sinica

06/01/17 / #20170153195

Method and device for detecting charged particles

Disclosed herein is a device for the detection of charged particles of a sample material. The device includes at least, a charge stripping means disposed in a first electric field, and a detection electrode disposed in a second electric field. ... Academia Sinica

05/18/17 / #20170137792

Recombinant polynucleotide sequence for producing astaxanthin and uses thereof

Disclosed herein are recombinant polynucleotide sequences, vectors, host cells and methods for producing astaxanthin. The recombinant polynucleotide sequence is designed to provide a higher level of astaxanthin precursors via a shorter metabolic pathway, and thereby attains higher level of end products (e.g., astaxanthin) with desired stereoisomeric form and/or esterified form.. ... Academia Sinica

05/04/17 / #20170121425

Humanized anti-ige antibodies that crosslink cd23 on b lymphocytes but do not sensitize mast cells

A novel humanized anti-ige antibody is disclosed. The antibody is capable of binding to free ige, membrane-bound ige on b lymphocytes, ige bound by cd23, but not to ige bound by high-affinity ige.fc receptor on mast cells. ... Academia Sinica

04/13/17 / #20170102387

Zanamivir phosphonate congeners with anti-influenza activity and determining oseltamivir susceptibility of influenza viruses

Methods and compositions for detection of drug resistant pathogens and treatment against infections thereof are provided. Methods for detection of oseltamivir-resistant influenza viruses by competitive binding assays utilizing non-oseltamivir influenza virus neuraminidase inhibitors and oseltamivir carboxylate are provided. ... Academia Sinica

03/23/17 / #20170082909

Supercontinuum generation apparatus and method

Apparatuses and methods for supercontinuum generation using a laser beam and a plurality of condensed state transparent plates are presented. As an example, plate material to be used for one of the plurality of plates is determined. ... Academia Sinica

03/23/17 / #20170081632

Composition and method for controlling insects and microorganims using pseudomonas taiwanensis

Described herein are method and compositions for controlling insects and microorganisms growth using pseudomonas taiwanensis and its culture broth.. . ... Academia Sinica

03/09/17 / #20170068214

Plasmonic multicolor meta-hologram

A phase-modulated optical component for the visible spectrum is provided and is capable of producing images in three primary colors. The phase-modulated optical component is primarily structured by a plurality of aluminum nanorods that are arranged in several two-dimensional arrays to form a plurality of pixels. ... Academia Sinica

02/23/17 / #20170051038

Recombinant decoy receptor 3 for treating spinal cord injury

Disclosed herein are methods for treating spinal cord injury using recombinant decoy receptor 3 (dcr3) polypeptide. Also disclosed herein are methods for improving the locomotor function recovery of a spinal cord injured subject with a dcr3 polypeptide.. ... Academia Sinica

02/23/17 / #20170049794

Pdia4 protein as a target for diagnosis, monitoring and treatment of diabetes

A pdia4 inhibitor for use in preventing, alleviating and/or treating diabetes and/or diabetes-related complications in a subject in need thereof is disclosed, wherein the pdia4 inhibitor does not comprise cytopiloyene. A pdia4 inhibitor and one other anti-diabetic agent for use in combination therapy in preventing, alleviating, treating diabetes and diabetes-related complications, and/or reversing diabetes in a subject in need thereof is also disclosed, wherein the pdia4 inhibitors for use in combination therapy may comprise cytopiloyene. ... Academia Sinica

02/16/17 / #20170044239

Phage-displayed antibody libraries and uses thereof

Disclosed herein are phage-displayed single-chain variable fragment (scfv) libraries, which comprised a plurality of scfvs with a specific sequence in each cdr. The present scfv libraries could be used to efficiently produce different antibodies with high binding affinity to h1 hemagglutinin of influenza virus. ... Academia Sinica

02/09/17 / #20170038378

Glycan arrays on ptfe-like aluminum coated glass slides and related methods

Aluminum coated glass slides provide a novel glycan array platform. Specifically, aluminum coated glass slides increase sensitivity of fluorescent based assay methods. ... Academia Sinica

01/19/17 / #20170016011

Method for high efficiency protein delivery into plastids

The present invention provides a recombinant dna molecule encoding a fusion protein, comprising a first dna sequence encoding a high-efficiency transit peptide operably linked to a second dna sequence encoding a passenger protein, wherein the high-efficiency transit peptide is selected from the group consisting of transit peptides of the precursors of translocon at the inner envelope membrane of chloroplasts 40 kd (prtic40), chaperonin 10-2 (prcpn10-2), fibrillin 1b (prfibrillin), atp sulfurylase 1 (praps1), atp sulfurylase 3 (praps3), 5′-adenylylsulfate reductase 3 (prapr3), stromal ascorbate peroxidase (prsapx), prtic40-e2a (a prtic40 variant), prcpn10-1-Δc7c37s (a chaperonin 10-1 variant), a functional fragment of any of the transit peptides and an equivalent thereof. And the present invention also provides a method of high efficiency delivery of a protein into plastids using the high-efficiency transit peptides.. ... Academia Sinica








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