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Affibody Ab patents


Recent patent applications related to Affibody Ab. Affibody Ab is listed as an Agent/Assignee. Note: Affibody Ab may have other listings under different names/spellings. We're not affiliated with Affibody Ab, we're just tracking patents.

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Polypeptides

The present disclosure relates to a class of engineered polypeptides having a binding affinity for carbonic anhydrase ix (caix), and provides a caix binding polypeptide comprising the sequence ex2x3x4ax6x7eix10x11lpn lx16x17x18qx20x21afix25x26lwd (seq id no. 369). ... Affibody Ab

Polypeptides

The present disclosure relates to a class of engineered polypeptides having a binding affinity for the neonatal fc receptor (in the following referred to as fcrn), and provides an fcrn binding polypeptide comprising the sequence ex2 x3 x4 ax6 x7 eirwlpnl x16x17 x18 qrx21 afix25 x26lx28 x29. The present disclosure also relates to the use of such an fcrn binding polypeptide as an agent for modifying pharmacokinetic and pharmacodynamic properties and as a therapeutic agent.. ... Affibody Ab

Method for reducing the immune response to a biologically active protein

A new use of a molecule comprising at least one moiety which is a biologically active protein and at least one moiety capable of binding to a serum albumin of a mammal is provided, for preparation of a medicament which elicits no or a reduced immune response upon administration to the mammal, as compared to the immune response elicited upon administration to the mammal of the biologically active protein per se. Also provided is a method of reducing or eliminating the immune response elicited upon administration of a biologically active protein to a human or non-human mammal, which comprises coupling the polypeptide to at least one moiety capable of binding to a serum albumin of the mammal.. ... Affibody Ab

Alzheimer abeta peptide binding polypeptide

The present disclosure relates to a class of engineered polypeptides having a binding affinity for amyloid β (aβ) peptides (in the following referred to as aβ), comprising the amino acid sequence ex2x3yx5x6nlx9ax11qlcax16ix18x19x20 ed. The present disclosure also relates to the use of such aβ peptide binding polypeptides as therapeutic, prognostic and/or diagnostic agents.. ... Affibody Ab

Il-17a-binding polypeptides

The present disclosure relates to a class of engineered polypeptides having a binding affinity for interleukin-17a (il-17a), and provides an il-17a binding polypeptide comprising the sequence ex2dx4ax6x7eix10x11 lpnl x16x17x18qx20x21afix25 x26lx28x29. Also disclosed is the use of such an interleukin-17a binding polypeptide as a diagnostic, prognostic and/or therapeutic agent.. ... Affibody Ab

New polypeptides

The present disclosure relates to dimers of engineered polypeptides having a binding affinity for the neonatal fc receptor fcrn, and provides an fcrn binding dimer, comprising a first monomer unit, a second monomer unit and an amino acid linker, wherein said first and second monomer unit search comprises an fcrn binding motif. Said fcrn binding dimer binds fcrn with higher capacity compared to said first monomer unit or second monomer unit alone. ... Affibody Ab

New polypeptide

The present disclosure relates to a class of engineered polypeptides having a binding affinity for interleukin-6, and provides an il-6 binding polypeptide comprising the sequence eex3x4awx7eih x11 lpnlx16x17x18qx20 x21afix25x26lx28x29. The present disclosure also relates to the use of such an il-6 binding polypeptide as a therapeutic, prognostic and/or diagnostic agent.. ... Affibody Ab

Polypeptide libraries with a predetermined scaffold

Populations of polypeptide variants based on a common scaffold, each polypeptide in the population comprising the scaffold amino acid sequence exxxaxxeix xlpnltxxqx xafixklxdd psqssellse akklndsq (seq id no: 1) or akyakexxxaxx eixxlpnltx xqxxafixkl xddpsqssel lseakklnds q (seq id no: 2), wherein each x individually corresponds to an amino acid residue which is varied in the population are disclosed. Also populations of polynucleotides, wherein each member encodes a member of a polypeptide population are disclosed. ... Affibody Ab








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