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Agios Pharmaceuticals Inc patents


Recent patent applications related to Agios Pharmaceuticals Inc. Agios Pharmaceuticals Inc is listed as an Agent/Assignee. Note: Agios Pharmaceuticals Inc may have other listings under different names/spellings. We're not affiliated with Agios Pharmaceuticals Inc, we're just tracking patents.

ARCHIVE: New 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 | Company Directory "A" | Agios Pharmaceuticals Inc-related inventors


Therapeutically active compositions and their methods of use

Provided are methods of treating a cancer characterized by the presence of a mutant allele of idh1/2 comprising administering to a subject in need thereof a compound described here.. . ... Agios Pharmaceuticals Inc

Therapeutically active compounds and their methods of use

Provided are compounds useful for treating cancer and methods of treating cancer, for example an advanced solid tumor, such as a glioma, or angioimmunoblastic t-cell lymphoma (aitl).. . ... Agios Pharmaceuticals Inc

Tablet compositions

. . Provided herein is a tablet comprising 2-methyl-1-[(4-[6-(trifluoromethyl)pyridin-2-yl]-6-{[2-(trifluoromethyl)pyridin-4-yl]amino}-1,3,5-triazin-2-yl)amino]propan-2-ol or a pharmaceutically acceptable salt thereof.. . ... Agios Pharmaceuticals Inc

Therapeutically active compounds and their methods of use

Provided are crystalline forms of 2-methyl-1-[(4-[6-(trifluoromethyl) pyridin-2-yl]-6-{[2-(trifluoromethyl)pyridin-4-yl]amino}-1,3,5-triazin-2-yl)amino]propan-2-ol mesylate useful for treating cancer and methods of treating cancer, comprising administering to a subject in need thereof said compound.. . ... Agios Pharmaceuticals Inc

Bicyclic pkm2 activators

Compounds and compositions comprising compounds that activate pyruvate kinase m2 (pkm2) are described herein. Also described herein are methods of using the compounds that activate pkm2 in the treatment of cancer.. ... Agios Pharmaceuticals Inc

N,6-bis(aryl or heteroaryl)-1,3,5-triazine-2,4-diamine compounds as idh2 mutants inhibitors for the treatment of cancer

Provided are compounds of formula (i), wherein: ring a and ring b are each independently an optionally substituted 5-6 membered monocyclic aryl or heteroaryl. The compounds are inhibitors of isocitrate dehydrogenase 2 (idh2) mutants useful for treating cancer.. ... Agios Pharmaceuticals Inc

Methods and compositions for cell-proliferation-related disorders

Methods of treating and evaluating subjects having neoactive mutants are described herein.. . ... Agios Pharmaceuticals Inc

Therapeutically active compounds and their methods of use

Provided are compounds useful for treating cancer and methods of treating cancer, comprising administering to a subject in need thereof a compound described herein.. . ... Agios Pharmaceuticals Inc

Pyruvate kinase activators for use in therapy

Described herein are methods for using compounds that activate pyruvate kinase.. . ... Agios Pharmaceuticals Inc

Therapeutic compositions and related methods of use

Compositions comprising compounds that modulate pyruvate kinase m2 (pkm2) are described herein. Also described herein are methods of using the compounds that modulate pkm2 in the treatment of cancer.. ... Agios Pharmaceuticals Inc

Therapeutically active compounds and their methods of use

Provided are compounds useful for treating cancer and methods of treating cancer, for example an advanced solid tumor, such as a glioma, or angioimmunoblastic t-cell lymphoma (aitl).. . ... Agios Pharmaceuticals Inc

Methods of treatment of malignancies

Provided are methods and compositions for treating cancers in patients carrying an idh1 mutation or idh2 mutation.. . ... Agios Pharmaceuticals Inc

Therapeutically active compositions and their methods of use

Provided are compounds of formula (i), wherein x, y, z, w, v, r2, r3 and m are defined as in the description. Their pharmaceutical compositions and their uses for treating cancers are also provided.. ... Agios Pharmaceuticals Inc

Therapeutic compounds and compositions

Compounds and compositions comprising compounds that modulate pyruvate kinase m2 (pkm2) are described herein. Also described herein are methods of using the compounds that modulate pkm2 in the treatment of cancer.. ... Agios Pharmaceuticals Inc

06/15/17 / #20170166541

Therapeutically active compositions and their methods of use

Compounds and compositions comprising compounds useful in the treatment of cancer are described herein.. . ... Agios Pharmaceuticals Inc

06/08/17 / #20170157132

Methods of treatment of malignancies

Provided are methods and compositions for treating cancers in patients carrying an idh1 mutation or idh2 mutation.. . ... Agios Pharmaceuticals Inc

05/18/17 / #20170137414

Compounds and their methods of use

Compounds and compositions comprising compounds that inhibit glutaminase are described herein. Also described herein are methods of using the compounds that inhibit glutaminase in the treatment of cancer.. ... Agios Pharmaceuticals Inc

04/20/17 / #20170107194

Therapeutically active compounds and their methods of use

Provided are compounds useful for treating cancer and methods of treating cancer comprising administering to a subject in need thereof a compound described herein.. . ... Agios Pharmaceuticals Inc

03/02/17 / #20170057994

Therapeutically active compounds and their methods of use

Provided are methods of treating a cancer characterized by the presence of a mutant allele of idh1/2 comprising administering to a subject in need thereof a compound described here.. . ... Agios Pharmaceuticals Inc

02/16/17 / #20170044620

Methods and compositions for cell-proliferation-related disorders

Methods of treating and evaluating subjects having neoactive mutants of idh (e.g., idh1 or idh2).. . ... Agios Pharmaceuticals Inc

02/16/17 / #20170044139

Therapeutically active compounds and their methods of use

Provided are compounds useful for treating cancer and methods of treating cancer comprising administering to a subject in need thereof a compound described herein.. . ... Agios Pharmaceuticals Inc

02/09/17 / #20170037031

Therapeutically active compounds and their methods of use

Provided are compounds useful for treating cancer and methods of making the compounds and intermediates described herein.. . ... Agios Pharmaceuticals Inc

01/19/17 / #20170015703

Therapeutically active compositions and their methods of use

Provided are methods of treating a cancer characterized by the presence of a mutant allele of idh1/2 comprising administering to a subject in need thereof a compound described here.. . ... Agios Pharmaceuticals Inc

01/19/17 / #20170014396

Pharmaceutical compositions of therapeutically active compounds

Provided are compounds and pharmaceutical compositions useful for treating cancer and methods of treating cancer comprising administering to a subject in need thereof a compound or pharmaceutical composition described herein.. . ... Agios Pharmaceuticals Inc

01/12/17 / #20170007661

Pharmaceutical compositions of therapeutically active compounds

Provided are compounds and pharmaceutical compositions useful for treating cancer and methods of treating cancer comprising administering to a subject in need thereof a compound or pharmaceutical composition described herein.. . ... Agios Pharmaceuticals Inc

01/12/17 / #20170007608

Activators of pyruvate kinase m2 and methods of treating disease

The invention described herein features methods, compositions, and kits that utilize activators of pyruvate kinase m2 (pkm2) for the treatment or amelioration of disorders related to pkm2 function and characterized by abnormally low levels of serine.. . ... Agios Pharmaceuticals Inc








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