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Ajinomoto Co Inc patents


Recent patent applications related to Ajinomoto Co Inc. Ajinomoto Co Inc is listed as an Agent/Assignee. Note: Ajinomoto Co Inc may have other listings under different names/spellings. We're not affiliated with Ajinomoto Co Inc, we're just tracking patents.

ARCHIVE: New 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 | Company Directory "A" | Ajinomoto Co Inc-related inventors


Crystallized oxalate decarboxylase and methods of use

Oxalate decarboxylase crystals, including stabilized crystals, such as cross-linked crystals of oxalate decarboxylase, are disclosed. Methods to treat a disorder associated with elevated oxalate concentration using oxalate decarboxylase crystals are also disclosed. ... Ajinomoto Co Inc

Heparosan-producing bacterium and heparosan manufacturing method

A method for producing heparosan is provided. Heparosan is produced by culturing an escherichia bacterium having a heparosan-producing ability and modified so that expression of one or more genes, such as rbsr, rbsk, rbsb, hsra, glgb, glgx, micf, rcsd, rcsb, ybix, ybil, ybij, ybic, ybib, rfah, nusg, pcor, pcos, pcoe, yhcn, yhco, aaeb, aaea, aaex, g1455, alpa, g1453, yrba, mlab, mlac, mlad, mlae, mlaf, yrbg, norw, ybji, ybjj, ybjk, rybb, yjjy, yjtd, thrl, thra, thrb, frua, psuk, ytft, yjff, fbp, yagu, paoa, paob, gsic, gsid, ylie, irp2, irp1, bhsa, ycfs, lepb, rnc, era, dapa, gcvr, bcp, hyfa, rpoe, nadb, yfic, srmb, g1414, g1413, nuoe, nuof, nuog, glmz, hemy, hemx, hemd, rlml, artq, artm, artj, rlmc, ybjo, yejo, yejm, yejl, rpos, ygbn, ygbm, ygbl, g3798, g3797, g3796, g3795, g3794, g3793, g3792, ryja, soxr, soxs, yjcc, yjcb, efeu, and efeo, is/are increased in a medium, and collecting heparosan from the medium.. ... Ajinomoto Co Inc

Method for producing n epsilon-acyl-l-lysine

The present invention provides a method for producing nε-dodecanoyl-l-lysine using an enzyme having properties suitable for the industrial production of nε-dodecanoyl-l-lysine. More specifically, the present invention provides a method for producing nε-acyl-l-lysine including reacting a carboxylic acid or a salt thereof and l-lysine or a salt thereof in the presence of a protein having an amino acid sequence of seq id no: 1; a protein having an amino acid sequence in which one or several amino acid residues are inserted, added, deleted, or substituted in the amino acid sequence of seq id no: 1 and having nε-acyl-l-lysine-specific aminoacylase activity; and a protein which has 90% or higher homology with the amino acid sequence of seq id no: 1 and having nε-acyl-l-lysine-specific aminoacylase activity.. ... Ajinomoto Co Inc

Method for producing aldehyde

A method is provided for producing an objective substance, for example, an aromatic aldehyde such as vanillin. The objective substance is produced from a carbon source or a precursor of the objective substance by using a coryneform bacterium that is able to produce the objective substance, wherein bacterium has been modified so that the activity of alcohol dehydrogenase is reduced.. ... Ajinomoto Co Inc

Crystallized oxalate decarboxylase and methods of use

. . Oxalate decarboxylase crystals, including stabilized crystals, such as cross-linked crystals of oxalate decarboxylase, are disclosed. Methods to treat a disorder associated with elevated oxalate concentration using oxalate decarboxylase crystals are also disclosed. ... Ajinomoto Co Inc

Method for producing gamma-glutamyl-valyl-glycine

A microorganism useful as an expression host for γ-glu-val synthetase and a method for producing γ-glu-val-gly using γ-glu-val synthetase expressed in the microorganism are provided. By using γ-glu-val synthetase expressed in a bacterium, such as escherichia bacteria, modified so that the activity of a protein encoded by a ybdk gene (ybdk) is reduced as an expression host, γ-glu-val-gly is produced from glu, val, and gly as raw materials.. ... Ajinomoto Co Inc

Moisturizer and cosmetic including the same

Moisturizers including an acyl neutral amino acid having an acyl group with a carbon atom number of 2 to 18, and salts thereof, and cosmetics containing such a moisturizer promote the production of moisturizing-related proteins, such as filaggrin, involucrin, transglutaminase 1, keratin 10, and loricrin, and provide a moisturizing effect.. . ... Ajinomoto Co Inc

Agricultural and horticultural material, and plant cultivation method which promote coloring in fruit

Coloring of fruits is promoted by applying a one or more the amino acids leucine, isoleucine, and/or phenylalanine, in combination with abscisic acid to a fruit plant, such as those of the genus vitaceae or rosaceae. The amino acid(s) and abscisic acid may be present in a solution(s) having concentrations of 0.2 mm to 100 mm and 0.1 μm to 10 mm, respectively.. ... Ajinomoto Co Inc

Culture medium for proliferating stem cell, which contains sulfated compound

. . A medium which comprises a fibroblast growth factor (fgf), and a sulfated compound or a pharmaceutically acceptable salt thereof at a concentration which promotes the growth of a stem cell in the presence of fgf, is useful for culturing stem cells.. . ... Ajinomoto Co Inc

Ameliorating agent for exercise-induced gastrointestinal disorders

Ingesting an agent containing cystine or a salt thereof, as an active ingredient, is effective for improving exercise-induced gastrointestinal disorder, providing an improvement effect equal to or better than that by the conventional technology on exercise-induced gastrointestinal disorders including exercise-induced decline in gastrointestinal tract barrier function.. . ... Ajinomoto Co Inc

Frozen dumpling and production method therefor, container for frozen dumpling, and packaging for frozen dumpling

The frozen gyoza dumpling of the present invention contains frozen gyoza dumpling itself 1 and frozen batter liquid 2 attached to the gyoza dumpling itself, wherein not less than 40% weight of the total attached frozen batter liquid 2 attaches to outer peripheral edge part of the bottom surface 14 of the gyoza dumpling itself and extends downwardly and sidewardly from the outer peripheral edge. In addition, the container of the present invention preferably contains the frozen gyoza dumpling of the present invention, the inside of the container has a supporting surface to support not less than 60% of the bottom surface 14 of the gyoza dumpling itself 1, and a recess part to preferably receive the frozen batter liquid. ... Ajinomoto Co Inc

Method for screening salty-taste modifying substance

A method for screening an objective substance such as a salty-taste modifying substance is provided. It is identified by using a tmc6 protein whether a test substance is an objective substance such as a salty-taste modifying substance.. ... Ajinomoto Co Inc

Method for producing l-amino acid

A method for producing an l-amino acid such as l-glutamic acid is provided. An l-amino acid is produced by culturing a bacterium having an l-amino acid-producing ability, which has been modified so that the activity of a c4-dicarboxylic acid-uptake carrier such as dcta, dcua, and dcub is increased, in a medium, and collecting the l-amino acid from the medium or cells of the bacterium.. ... Ajinomoto Co Inc

Chelated iron-containing culture medium for neural stem cells

. . . . Culture media, which contain chelated iron, promote cell proliferation of neural stem cells and/or neural progenitor cells while maintaining undifferentiated state and multipotency.. . ... Ajinomoto Co Inc

02/15/18 / #20180044703

Method for producing an acidic substance having a carboxyl group

An acidic substance having a carboxyl group is produced by culturing in a medium a microorganism which has been modified to enhance expression of the ybjl gene, and collecting the acidic substance having a carboxyl group from the medium.. . ... Ajinomoto Co Inc

02/08/18 / #20180037918

Method for secretory production of protein

A novel technique for improving secretory production of a heterologous protein by coryneform bacteria is described, as well as a method for secretory production of a heterologous protein. A coryneform bacterium is described that has been modified to have a specific mutation so as to harbor a phos gene, and when cultured, is able to to produce a heterologous protein by secretory production.. ... Ajinomoto Co Inc

01/18/18 / #20180017570

Evaluating method, evaluating apparatus, evaluating program product, evaluating system, and terminal apparatus

An evaluating method includes an evaluating step of evaluating a state of lung cancer for a subject to be evaluated using a concentration value of at least one of homoarginine, gaba, 3-me-his, adma, spermine, spermidine, cystathionine, sarcosine, aaiba, baiba, putrescine, n-acetyl-l-lys, hypotaurine, baba, and ethylglycine in blood of the subject.. . ... Ajinomoto Co Inc

01/18/18 / #20180017545

Evaluating method, evaluating apparatus, evaluating program product, evaluating system, and terminal apparatus

An evaluating method includes an evaluating step of evaluating a future risk of relapse of ulcerative colitis for a subject to be evaluated having ulcerative colitis in a remission phase using a concentration value of histidine, albumin, hemoglobin, or glutamic acid in blood of the subject.. . ... Ajinomoto Co Inc

01/18/18 / #20180016580

Morpholino oligonucleotide manufacturing method

Using a morpholino nucleotide wherein 5′-hydroxy group or a hydroxy group present on the substituent of the 5′-hydroxy group is protected by a protecting group having an alkyl group having not less than 10 and not more than 300 carbon atoms and/or an alkenyl group having not less than 10 and not more than 300 carbon atoms as a starting material, a method capable of efficiently producing the morpholino oligonucleotide in a high yield by a liquid phase synthesis can be provided.. . ... Ajinomoto Co Inc

01/18/18 / #20180016554

Human serum albumin-containing culture medium for growth of neural stem cells

A medium, which contains human serum albumin, is useful for proliferating neural stem cells and/or neural progenitor cells.. . ... Ajinomoto Co Inc

11/09/17 / #20170320904

Precipitation promoter and precipitation method in which same is used

. . . . . . . . Precipitation promoters, which are an organic compound having one or more linear aliphatic hydrocarbon groups having not less than 10 carbon atoms, wherein the aliphatic hydrocarbon group has not less than 20 carbon atoms in total are useful for precipitating an organic compound protected by an organic group having one or more aliphatic hydrocarbon groups having not less than 10 carbon atoms from a solvent.. . ... Ajinomoto Co Inc

10/05/17 / #20170290149

Resin sheet

. . Resin sheets which includes a support and a resin composition layer in contact on the support, and which are characterized in that an extracted water conductivity a of a cured product of the resin composition layer when extracted at 120° c. For 20 hours is 50 μs/cm or less and an extracted water conductivity b of the cured product of the resin composition layer when extracted at 160° c. ... Ajinomoto Co Inc

10/05/17 / #20170290148

Method for producing printed wiring board

Printed wiring boards with reduced curing unevenness and the like may be produced by (a) preparing an adhesive sheet having a support and a resin composition layer provided on the support, (b) laminating the adhesive sheet on an internal layer substrate so that the resin composition layer is in contact with the internal layer substrate, and (c) thermally curing the adhesive sheet by heating from t1 (° c.) to t2 (° c.), to form an insulating layer, wherein the adhesive sheet is thermally cured so that a relation of y>2700x is satisfied in which x is the sum of a difference between a maximum expansion rate of the support in the md direction during heating from t1 (° c.) to t2 (° c.) and an expansion rate of the support at the end of heating and a difference between a maximum expansion rate of the support in the td direction during heating from t1 (° c.) to t2 (° c.) and an expansion rate of the support at the end of heating and y is the lowest melt viscosity of the resin composition layer at 120° c. Or higher.. ... Ajinomoto Co Inc

09/21/17 / #20170268033

Method of analyzing l-tryptophan in biological samples, and kit used therein

Disclosed is a method for quantifying l-tryptophan involving a step for mixing a specimen, l-tryptophan oxidase, and water, a step for allowing the obtained reaction solution to stand a predetermined period of time in the presence of oxygen, and a step for measuring the reaction product resulting from action of enzymes present in the reaction solution after allowing to stand. The l-tryptophan oxidase has a given amino acid sequence and has oxidase activity that generates hydrogen peroxide and ammonia by acting on the l-tryptophan in the presence of oxygen and water. ... Ajinomoto Co Inc

09/14/17 / #20170260127

Aqueous solution containing bis(n epsilon lauroyllysine)dicarboxylic acid diamide and/or salt thereof, and method for producing same

. . The present invention provides a method of producing an aqueous solution containing bis(nε-lauroyl lysine)dicarboxylic acid diamide and/or a salt thereof, and having a ph of 9-11, which includes a first step of reacting nε-lauroyl lysine and/or a salt thereof with dicarboxylic acid dichloride in a water solvent having a ph of 12-14 to form bis(nε-lauroyl lysine)dicarboxylic acid diamide and/or a salt thereof, a second step of adjusting the aqueous solution obtained in the first step to ph 7.5-8.5, a third step of adding nε-lauroyl lysine to the aqueous solution obtained in the second step and filtering the mixture, and a fourth step of adjusting the aqueous solution obtained in the third step to ph 9-11.. . ... Ajinomoto Co Inc

08/03/17 / #20170221745

Support, adhesive sheet, laminated structure, semiconductor device, and method for manufacturing printed wiring board

. . A method for manufacturing a printed wiring board which includes: step (a) of laminating an adhesive sheet including a support and a resin composition layer bonded to the support to an inner layer board so that the resin composition layer is bonded to the inner layer board; step (b) of thermally curing the resin composition layer to form an insulating layer; and step (c) of removing the support, in this order, in which the support satisfies a condition (md1): a maximum expansion coefficient emd in an md direction at 120° c. Or more is less than 0.2% and a condition (td1): a maximum expansion coefficient etd in a td direction at 120° c. ... Ajinomoto Co Inc

08/03/17 / #20170218361

Morpholino oligonucleotide manufacturing method

Morpholino oligonucleotides can be produced efficiently in a high yield by a liquid-phase synthesis method, which includes subjecting a reaction mixture of a condensation reaction to an extraction operation and separating the morpholino oligonucleotide as a resultant product to the organic layer side.. . ... Ajinomoto Co Inc

08/03/17 / #20170218305

Transparent solid detergent

The present invention provides a transparent solid detergent containing (a) n-acyl acidic amino acid salt, (b) acylglycine salt and (c) polyvalent alcohol, at a proportion of (a) 4.5-5000 parts by weight and (c) 2.5-2400 parts by weight, per 1 part by weight of (b), which suppresses coloration by heating during production, is superior in preservation stability at low temperature and high temperature, is low irritant, and shows good sense of use.. . ... Ajinomoto Co Inc

07/20/17 / #20170206335

Evaluating method, evaluating apparatus, evaluating program product, evaluating system, and terminal apparatus

. . An evaluating method includes an evaluating step of evaluating a future risk of lifestyle-related disease for a subject to be evaluated using a concentration value of an amino acid included in amino acid concentration data on the concentration value of the amino acid in blood collected from the subject.. . ... Ajinomoto Co Inc

06/01/17 / #20170154841

Resin composition

. . Resin compositions containing (a) an epoxy resin, (b) a curing agent, and (c) an inorganic filler in which the content of (c) the inorganic filler is 55% by mass or higher with respect to 100% by mass of a non-volatile component within the resin composition, the average particle diameter of (c) the inorganic filler is 0.05 to 0.35 μm, the product of the specific surface area (m2/g) of (c) the inorganic filler and the true density of (c) the inorganic filler is 1 to 77 m2/g and the moisture permeation of a cured product obtained by thermally cured the resin composition is 0.05 to 2.8 g˜mm/m2·24 h are useful for making printed wiring boards.. . ... Ajinomoto Co Inc

05/18/17 / #20170137563

Coated particles

. . An object of the present invention is to provide curing agent composite particles for epoxy resin, which are less likely to aggregate, and are excellent in storage stability and solvent resistance. Coated particles of the present invention comprise (a) curing agent particles for epoxy resin, and (b) an alkoxy oligomer, wherein the surfaces of the curing agents for epoxy resin particle are coated with the alkoxy oligomer.. ... Ajinomoto Co Inc

05/04/17 / #20170121743

Method for producing l-amino acid of glutamate family

A method for producing an l-amino acid of glutamate family such as l-glutamic acid is provided. An l-amino acid of glutamate family is produced by culturing a coryneform bacterium having an ability for producing an l-amino acid of glutamate family, which has been modified so that the activity of an α-ketoglutaric acid (α-kg) uptake carrier is increased, in a medium, and collecting the l-amino acid of glutamate family from the medium.. ... Ajinomoto Co Inc

04/27/17 / #20170112751

Cosmetic composition

A method for perming or coloring hair, in which hair is treated with a cosmetic composition including a protein-glutaminase and not including an alkaline substance. A method of enhancing hair-permeation of an active ingredient included in a cosmetic composition, in which a protein glutaminase is included in the cosmetic composition. ... Ajinomoto Co Inc

03/30/17 / #20170087078

Cosmetic composition containing 3-o-alkyl-l-ascorbic acid or salt thereof

. . The present invention provides a cosmetic composition containing (a) 3-o-alkyl-l-ascorbic acid wherein the alkyl group has 8-12 carbon atoms or a salt thereof, (b) one or more kinds of nonionic surfactants selected from the group consisting of polyoxyethylene polyoxypropylene alkyl ether, polyoxyethylene sorbitan fatty acid ester, polyoxyethylene alkyl ether and polyoxyethylene alkenyl ether, and having an hlb value of 12.5-17, and (c) one or more kinds of oil agents selected from the group consisting of amino acid ester, dimer acid ester, hydroxy acid ester, alkyl glyceryl ether and alkenyl glyceryl ether, which is superior in solubilization stability, preservation stability and sense of use, and free of time-dependent development of an odor which poses a problem when in use.. . ... Ajinomoto Co Inc

03/23/17 / #20170086306

Method for manufacturing wiring board

Wiring boards, including an embedded type wiring boards and flexible wiring boards, may be produce by: (1) preparing a wiring layer-attached base including a base and a wiring layer provided on at least one surface of the base, (2) laminating an adhesive sheet including (i) a thermosetting resin composition layer and (ii) a resin film layer on the wiring layer-attached base so that the wiring layer will be embedded in (i) the thermosetting resin composition layer and performing thermal curing to form an insulating layer, (3) forming via holes in the insulating layer, (4) forming a conductor layer, and (5) removing the base.. . ... Ajinomoto Co Inc

03/16/17 / #20170073714

Method for producing l-amino acids

. . A method for producing an l-amino acid is provided. An l-amino acid is produced by culturing a bacterium belonging to the family enterobacteriaceae and having an l-amino acid-producing ability, wherein the bacterium has been modified so that the activity of aconitase is increased, or the activities of aconitase and acetaldehyde dehydrogenase are increased, in a medium, and collecting the l-amino acid from the medium or cells of the bacterium.. ... Ajinomoto Co Inc

03/09/17 / #20170067085

Yeast, yeast extract containing gamma-glu-abu, and a method for producing the same

A yeast extract containing 0.2% or more of γ-glu-abu based on dry weight of the yeast extract is produced by culturing a yeast, such as saccharomyces cervisiae or candida utilis, in a medium containing a compound selected from abu (l-2-aminobutyric acid) and γ-glu-abu (l-γ-glutamyl-l-2-aminobutyric acid), and preparing a yeast extract from the obtained cells.. . ... Ajinomoto Co Inc

02/16/17 / #20170044513

Protein deamidase

A novel protein deamidase having an activity of directly acting on a side chain amide group of an asparagine residue in a protein to form a side chain carboxyl group and release ammonia, a microorganism that produces the same, a gene encoding the same, a method for producing the same, and use of the same are provided. A bacterium classified into the class actinobacteria is cultured to generate protein deamidase, and the enzyme is collected from culture.. ... Ajinomoto Co Inc

02/09/17 / #20170035721

Composition for preventing or improving peripheral neuropathy

. . Compositions which contain an amino acid containing serine and a lipid containing a n-3 fatty acid are useful for the prophylaxis or improvement of peripheral neuropathy.. . ... Ajinomoto Co Inc

01/12/17 / #20170009200

Medium for stem cell use

. . Culture media which contain a water-soluble polymer, such as polyvinyl alcohol and the like, and albumin, and the like, are useful for the proliferation of stem cells, and show good culture results, particularly with ips cells, and maintain the stability of the medium properties, as well as using a reduced amount of albumin.. . ... Ajinomoto Co Inc

01/12/17 / #20170008922

Branched chain-containing aromatic compound

The present invention provides a particular branched chain-containing aromatic compound. The branched chain-containing aromatic compound of the present invention is easily-soluble in isopropyl acetate superior in liquid-separation operability, and can be used for a production method of peptide and the like, which provides a final product simply by extraction separation, without crystallization and isolation of each intermediate in each step.. ... Ajinomoto Co Inc

01/05/17 / #20170000122

Agricultural and horticultural composition and method for cultivating plant

A composition for agricultural or horticultural application, which contains isoleucine as an active ingredient, and is sprinkled on a fruit vegetable, fruit tree, or grain plant, or a harvested fruit as a solution having an isoleucine concentration of 0.5 to 75 mm, is sprinkled on a leaf surface and/or a fruit of a plant to provide at least one of promotion of blooming, promotion of the appearance of the fruit, improvement in number of fruit produced, promotion of ripening of fruit, improvement in essential amino acid and/or γ-aba content, promotion of carotenoid synthesis, and improvement in antioxidant capacity.. . ... Ajinomoto Co Inc








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