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Alderbio Holdings Llc patents


Recent patent applications related to Alderbio Holdings Llc. Alderbio Holdings Llc is listed as an Agent/Assignee. Note: Alderbio Holdings Llc may have other listings under different names/spellings. We're not affiliated with Alderbio Holdings Llc, we're just tracking patents.

ARCHIVE: New 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 | Company Directory "A" | Alderbio Holdings Llc-related inventors


Anti-cgrp compositions and use thereof

The present invention is directed to antibodies and fragments thereof having binding specificity for cgrp. Another embodiment of this invention relates to the antibodies described herein, and binding fragments thereof, comprising the sequences of the vh, vl and cdr polypeptides described herein, and the polynucleotides encoding them. ... Alderbio Holdings Llc

Anti-cgrp compositions and use thereof

The present invention is directed to antibodies and fragments thereof having binding specificity for cgrp. Another embodiment of this invention relates to the antibodies described herein, and binding fragments thereof, comprising the sequences of the vh, vl and cdr polypeptides described herein, and the polynucleotides encoding them. ... Alderbio Holdings Llc

Anti-cgrp compositions and use thereof

The present invention is directed to antibodies and fragments thereof having binding specificity for cgrp. Another embodiment of this invention relates to the antibodies described herein, and binding fragments thereof, comprising the sequences of the vh, vl and cdr polypeptides described herein, and the polynucleotides encoding them. ... Alderbio Holdings Llc

Anti-cgrp compositions and use thereof

The present invention is directed to antibodies and fragments thereof having binding specificity for cgrp. Another embodiment of this invention relates to the antibodies described herein, and binding fragments thereof, comprising the sequences of the vh, vl and cdr polypeptides described herein, and the polynucleotides encoding them. ... Alderbio Holdings Llc

Antibodies to il-6 and use thereof

The present invention is directed to antibodies and fragments thereof and humanized versions thereof having binding specificity for il-6. Another embodiment of this invention relates to the antibodies described herein, and binding fragments thereof, comprising the sequences of the vh, vl and cdr polypeptides described herein, and the polynucleotides encoding them. ... Alderbio Holdings Llc

In vivo imaging using anti-il-6 antibodies

The present invention is directed to therapeutic methods using il-6 antagonists such as an ab 1 antibody or antibody fragment having binding specificity for il-6 to prevent or treat disease or to improve survivability or quality of life of a patient in need thereof. In preferred embodiments these patients will comprise those exhibiting (or at risk of developing) an elevated serum c-reactive protein level, reduced serum albumin level, elevated d-dimer or other cogulation cascade related protein(s), cachexia, fever, weakness and/or fatigue prior to treatment. ... Alderbio Holdings Llc

Antibodies to il-6 and use thereof

The present invention is directed to antibodies and fragments thereof and humanized versions thereof having binding specificity for il-6. Another embodiment of this invention relates to the antibodies described herein, and binding fragments thereof, comprising the sequences of the vh, vl and cdr polypeptides described herein, and the polynucleotides encoding them. ... Alderbio Holdings Llc

Anti-glycoprotein antibodies and uses thereof

A new class of antibodies having specificity for glycoproteins are described. The antibodies are shown to bind sensitively and specifically to mannosylated proteins, such as proteins produced by fungi. ... Alderbio Holdings Llc

Antagonists of il-6 to prevent or treat cachexia, weakness, fatigue, and/or fever

The present invention is directed to therapeutic methods and compositions, especially subcutaneous and intravenous composition using antibodies and fragments thereof having binding specificity for il-6 to prevent or treat cachexia, fever, weakness and/or fatigue in a patient in need thereof. In preferred embodiments, the anti-il-6 antibodies will be humanized and/or will be aglycosylated. ... Alderbio Holdings Llc

Antibodies to il-6 and use thereof

The present invention is directed to antibodies and fragments thereof having binding specificity for il-6. Another embodiment of this invention relates to the antibodies described herein, and binding fragments thereof, comprising the sequences of the vh, vl and cdr polypeptides described herein, and the polynucleotides encoding them. ... Alderbio Holdings Llc

Antibodies to il-6 and use thereof

The present invention is directed to therapeutic methods using il-6 antagonists such as an ab1 antibody or antibody fragment having binding specificity for il-6 to prevent or treat disease or to improve survivability or quality of life of a patient in need thereof. In preferred embodiments these patients will comprise those exhibiting (or at risk of developing) an elevated serum c-reactive protein level, reduced serum albumin level, elevated d-dimer or other coagulation cascade related protein(s), cachexia, fever, weakness and/or fatigue prior to treatment. ... Alderbio Holdings Llc

Anti-il-6 antibodies for the treatment of arthritis

The present invention is directed to therapeutic methods using il-6 antagonists such as anti-il-6 antibodies and fragments thereof having binding specificity for il-6 to prevent or treat rheumatoid arthritis.. . ... Alderbio Holdings Llc

Antagonists of il-6 to raise albumin and/or lower crp

The present invention is directed to therapeutic methods using il-6 antagonists such as antibodies and fragments thereof having binding specificity for il-6 to improve survivability or quality of life of a patient in need thereof. In preferred embodiments, the anti-il-6 antibodies will be humanized and/or will be aglycosylated. ... Alderbio Holdings Llc

Antibodies to il-6 and use thereof

The present invention is directed to antibodies and fragments thereof and humanized versions thereof having binding specificity for il-6. Another embodiment of this invention relates to the antibodies described herein, and binding fragments thereof, comprising the sequences of the vh, vl and cdr polypeptides described herein, and the polynucleotides encoding them. ... Alderbio Holdings Llc

01/18/18 / #20180016331

Methods of preventing or treating pain using anti-ngf antibodies

Antibodies and antibody fragments thereof with binding specificity to human nerve growth factor (ngf) and methods of use for treating pain. Methods of treating pain or eliciting an analgesic effect comprising administering an effective amount of an anti-human ngf antibody or antibody fragment thereof, which inhibits the association of ngf with trka, and/or p75. ... Alderbio Holdings Llc

11/23/17 / #20170334986

Antagonists of il-6 to raise albumin and/or lower crp

The present invention is directed to therapeutic methods using il-6 antagonists such as antibodies and fragments thereof having binding specificity for il-6 to improve survivability or quality of life of a patient in need thereof. In preferred embodiments these patients will comprise those exhibiting (or at risk of developing) an elevated serum c-reactive protein level or a reduced serum albumin level prior to treatment. ... Alderbio Holdings Llc

07/13/17 / #20170198036

Antagonists of il-6 to prevent or treat cachexia, weakness, fatigue, and/or fever

The present invention is directed to therapeutic methods using antibodies and fragments thereof having binding specificity for il-6 to prevent or treat cachexia, fever, weakness and/or fatigue in a patient in need thereof. In preferred embodiments these patients will comprise those exhibiting (or at risk of developing) an elevated serum c-reactive protein level. ... Alderbio Holdings Llc

06/22/17 / #20170174754

Anti-cgrp compositions and use thereof

The present invention is directed to antibodies and fragments thereof having binding specificity for cgrp. Another embodiment of this invention relates to the antibodies described herein, and binding fragments thereof, comprising the sequences of the vh, vl and cdr polypeptides described herein, and the polynucleotides encoding them. ... Alderbio Holdings Llc

05/18/17 / #20170137508

Methods of preventing inflammation and treating pain using anti-ngf compositions

This invention pertains to monovalent agents, including fab fragments and monovalent monoclonal antibodies analogous to metmab, having binding specificity to human nerve growth factor (“ngf”), and methods of treating pain in an individual wherein there is no substantial increase in the inflammatory response of the individual following administration of the monovalent agents.. . ... Alderbio Holdings Llc

05/18/17 / #20170137500

Antibody purification and purity monitoring

Processes for producing and purifying recombinant proteins are disclosed. In particular, the present disclosure provides processes of producing and purifying multi-subunit proteins expressed in yeast or filamentous fungal cells. ... Alderbio Holdings Llc

04/27/17 / #20170115307

Antibodies to il-6 and use thereof

The present invention is directed to therapeutic methods using il-6 antagonists such as an ab1 antibody or antibody fragment having binding specificity for il-6 to prevent or treat disease or to improve survivability or quality of life of a patient in need thereof. In preferred embodiments these patients will comprise those exhibiting (or at risk of developing) an elevated serum c-reactive protein level, reduced serum albumin level, elevated d-dimer or other coagulation cascade related protein(s), cachexia, fever, weakness and/or fatigue prior to treatment. ... Alderbio Holdings Llc

04/27/17 / #20170114122

Regulation of glucose metabolism using anti-cgrp antibodies

The present disclosure provides methods for the prevention or treatment of metabolic disorders. In exemplary embodiments, methods of administering an anti-cgrp antibody are provided, optionally in combination with a second agent, wherein peripheral and/or hepatic glucose utilization is increased, thereby preventing or treating diseases and disorders associated with insulin resistance. ... Alderbio Holdings Llc

04/20/17 / #20170107280

Antibodies to hgf and compositions containing

The present invention is directed to antibodies and fragments thereof having binding specificity for hgf. Another embodiment of this invention relates to the antibodies described herein, and binding fragments thereof, comprising the sequences of the vh, vl and cdr polypeptides described herein, and the polynucleotides encoding them. ... Alderbio Holdings Llc

02/23/17 / #20170051048

Methods of treating pain using anti-ngf antibodies that selectively inhibit the association of ngf with trka, without affecting the association of ngf with p75

This invention pertains to ngf antagonists including antibodies and fragments thereof (including fab fragments) having binding specificity to human nerve growth factor (hereinafter “ngf”), and methods of using one or more of said antibodies and fragments thereof to treat pain in an individual. More specifically the invention relates to methods of treating pain or eliciting an analgesic effect in an individual, comprising administering an effective amount of an ngf antagonist, e.g., an anti-human ngf antibody or fragment thereof or another moiety, such as a nucleic acid or polypeptide such as a fragment of ngf or trka which inhibits the association of ngf with trka, without appreciably inhibiting the association of ngf with p75. ... Alderbio Holdings Llc








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