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Apicore Us Llc patents

Recent patent applications related to Apicore Us Llc. Apicore Us Llc is listed as an Agent/Assignee. Note: Apicore Us Llc may have other listings under different names/spellings. We're not affiliated with Apicore Us Llc, we're just tracking patents.

ARCHIVE: New 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 | Company Directory "A" | Apicore Us Llc-related inventors

Novel polymorphs of ponatinib hydrochloride

Novel crystalline ponatinib hydrochloride forms designated form alpha and form beta are disclosed. Form alpha is characterized by data selected from an xrpd pattern with peaks at about 6.5, 9.0, 12.25, 14.4, 16.70, 19.6, 22.2, 24.5, 28.2±0.2 degrees 2-theta; an xrpd pattern substantially as depicted in fig. ... Apicore Us Llc

Novel polymorph of regadenoson and process for preparation thereof

Processes are provided for the preparation of a stable polymorphic form c of regadenoson, the process involving steps of a) obtaining a solution of regadenoson in benzyl alcohol solvent, b) maintaining the reaction mixture of step a) to about 10° c. To about 90° c., and c) isolating the stable polymorphic form c of regadenoson. ... Apicore Us Llc

Process for preparation of isosulfan blue

Isosulfan blue and processes for the preparation thereof are provided. A process is also provided for preparation of the intermediate, 2-chlorobenzaldehyde-5-sulfonic acid, sodium salt of formula (2), used in the preparation thereof and a procedure for the isolation of benzaldehyde-2,5-disulfonic acid, di-sodium salt of the formula (3). ... Apicore Us Llc

Processes for making ponatinib and intermediates thereof

Methods are disclosed for making 3-(imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-n-[4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]benzamide, intermediates and pharmaceutically acceptable salts thereof.. . ... Apicore Us Llc

Methods of making carfilzomib and intermediates thereof

Racemization-free methods are disclosed for the synthesis of carfilzomib. Novel intermediates and methods of making carfilzomib employing fragment condensation using the novel intermediates are disclosed. ... Apicore Us Llc

Process for the preparation of novel polymorphic forms of 5-fluoro-1,3-dihydro-1-hydroxy-2,1- benzoxaborole

Novel polymorphic forms of tavaborole, form a and form b, and methods of making same are disclosed. Methods are disclosed for the manufacture of the novel polymorphic forms a and b. ... Apicore Us Llc

Methods of making eribulin mesylate

Novel processes are disclosed for the preparation of eribulin mesylate. Novel intermediate compounds used in the processes for making eribulin mesylate as well as processes for making the intermediates are disclosed.. ... Apicore Us Llc

Process for preparation and purification of pomalidomide

Processes are disclosed for making pomalidomide which involve reducing 2-(2,6-dioxopiperidin-3-yl)-4-nitroisoindoline-1,3-dione using a catalyst and at least one solvent. The process may include reacting 3-nitrophthalic anhydride with α-amino glutarimide hydrochloride to obtain the 2-(2,6-dioxopiperidin-3-yl)-4-nitroisoindoline-1,3-dione. ... Apicore Us Llc

Methods of making netupitant and intermediates thereof

Methods are disclosed for the preparation of netupitant and pharmaceutically acceptable salts thereof which are novel, easily reproducible, environmentally safe and cost effective. The methods may employ inexpensive starting materials and the preparation processes for intermediates are simple and highly reproducible. ... Apicore Us Llc

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