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Arcturus Therapeutics Inc patents


Recent patent applications related to Arcturus Therapeutics Inc. Arcturus Therapeutics Inc is listed as an Agent/Assignee. Note: Arcturus Therapeutics Inc may have other listings under different names/spellings. We're not affiliated with Arcturus Therapeutics Inc, we're just tracking patents.

ARCHIVE: New 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 | Company Directory "A" | Arcturus Therapeutics Inc-related inventors


Una oligomers for therapeutics with prolonged stability

This invention provides una oligomers for therapeutics having prolonged stability. The una oligomers can be composed of one or more 2′-3′-seco-nucleomonomers and one or more natural or non-natural nucleotide monomers. ... Arcturus Therapeutics Inc

Una oligomers and compositions for treating amyloidosis

. . . . . . This invention encompasses compounds and compositions useful in methods for medical therapy, in general, for inhibiting expression of a ttr gene in a subject. The compounds have a first strand and a second strand, the monomers comprising una monomers and nucleic acid monomers, and the compounds are targeted to a sequence of a ttr gene.. ... Arcturus Therapeutics Inc

Therapeutic oligomers for treating amyloidosis

This invention provides pharmaceutical compositions containing a una oligomer targeted to ttr and a pharmaceutically acceptable carrier. The compositions can be used in methods for treating or preventing ttr-related amyloidosis in a primate. ... Arcturus Therapeutics Inc

Therapeutic una oligomers and uses thereof

This invention provides una oligomers for regulating the expression of a target gene. The una oligomers contain una monomer linkers, and may contain one or more nucleotides modified with a 2′-o-methyl group, one or more nucleotides modified with a 2′-deoxy-2′-fluoro group, and one or more phosphorothioate or chiral phosphorothioate intermonomer linkages. ... Arcturus Therapeutics Inc

Trinucleotide mrna cap analogs

What is described is a trinucleotide cap analog comprising m7g(5′)p3-n1pn2 for increased efficiency of in vitro transcription of m7g(5′)p3-rna, wherein m7g is n7-methylguanosine or analog, (5′)p3 is a 5′,5′-triphosphate bridge, and n1 or n2 or both ribonucleotide analogs linked to each other by a phosphate, p, and wherein the trinucleotide cap analog increases the efficiency of in vitro transcription.. . ... Arcturus Therapeutics Inc

Messenger una molecules and uses thereof

. . . . This invention provides a range of translatable messenger una (muna) molecules. The muna molecules can be translated in vitro and in vivo to provide an active polypeptide or protein, or to provide an immunization agent or vaccine component. ... Arcturus Therapeutics Inc

Molecules and agents for treating hepatitis b virus

. . . . . . This invention encompasses compounds and compositions useful in methods for medical therapy, in general, for inhibiting hepatitis b virus in a subject. The compounds have a first strand and a second strand, each of the strands being 19-29 monomers in length, the monomers comprising una monomers and nucleic acid monomers, and the compounds are targeted to a sequence of an hbv genome.. ... Arcturus Therapeutics Inc

Allele selective gene editing and uses thereof

. . . . This invention encompasses compounds, structures, compositions and methods for therapeutic guide molecules that direct crispr gene editing. A guide molecule for directing gene editing can be allele selective, or disease allele selective, and can exhibit reduced off target activity. ... Arcturus Therapeutics Inc

Compositions and agents against hepatitis b virus and uses thereof

. . This invention encompasses compounds and compositions useful in methods for medical therapy, in general, for inhibiting hepatitis b virus in a subject. The compounds have a first strand and a second strand, each of the strands being 19-29 monomers in length, the monomers comprising una monomers and nucleic acid monomers, and the compounds are targeted to a sequence of an hbv genome.. ... Arcturus Therapeutics Inc








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