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Ardea Biosciences Inc patents


Recent patent applications related to Ardea Biosciences Inc. Ardea Biosciences Inc is listed as an Agent/Assignee. Note: Ardea Biosciences Inc may have other listings under different names/spellings. We're not affiliated with Ardea Biosciences Inc, we're just tracking patents.

ARCHIVE: New 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 | Company Directory "A" | Ardea Biosciences Inc-related inventors


Cxcr-2 inhibitors for treating crystal arthropathy disorders

N-(2-((2,3-difluorobenzyl)thio)-6-(((2r,3s)-3,4-dihydroxybutan-2-yl)oxy)pyrimidin-4-yl)azetidine-1-sulfonamide (compound 3) and n-(6-(((2r,3s)-3,4-dihydroxy butan-2-yl)oxy)-2-((4-fluoro benzyl)thio)pyrimidin-4-yl)-3-methyl-azetidine-1-sulfonamide (compound 4) are known chemokine modulators and are therefore useful in the treatment of diseases/conditions in which modulation of chemokine receptor activity is beneficial. In particular, provided herein are compositions and methods for the treatment and prevention of gout.. ... Ardea Biosciences Inc

Polymorphic forms of 2-(5-bromo-4-(4-cyclopropylnaphthalen-1-yl)-4h-1,2,4-triazol-3-ylthio)acetic acid and uses thereof

Crystalline polymorph forms of 2-(5-bromo-4-(4-cyclopropyl naphthalen-1-yl)-4h-1,2,4-triazol-3-ylthio)acetic acid are described. Pharmaceutical compositions and the uses of such compounds, compound forms, and compositions for the treatment of a variety of diseases and conditions are also presented.. ... Ardea Biosciences Inc

Cxcr-2 inhibitors for treating disorders

N-(6-(((2r,3s)-3,4-dihydroxy butan-2-yl)oxy)-2-((4-fluoro benzyl)thio)pyrimidin-4-yl)-3-methylazetidine-1-sulfonamide (compound 4), a known chemokine modulator, in combination with colchicine is useful in the treatment of diseases/conditions in which modulation of chemokine receptor activity, interleukin-1 (il-1) activity, and/or myeloperoxidase (mpo) activity is beneficial. In particular, provided herein are compositions and methods for the treatment and prevention of such diseases/conditions.. ... Ardea Biosciences Inc

S-triazolyl alpha-mercapto acetanilides as inhibitors of hiv reverse transcriptase

. . A series of s-triazolyl α-mercaptoacetanilides having general structure (1) are provided, where q is co2h, conr2, so3h, or so2nr2. The compounds inhibit several variants of the reverse transcriptase of hiv, and are useful in the treatment of hiv infections.. ... Ardea Biosciences Inc

Atropisomers of triazole derivative

Atropisomers of 2-(5-bromo-4-(4-cyclopropyl naphthalen-1-yl)-4h- 1,2,4-triazol-3-ylthio)acetic acid are described. Pharmaceutical compositions and the uses of such compounds, compound forms, and compositions for the treatment of a variety of diseases and conditions are also presented.. ... Ardea Biosciences Inc

Novel compounds and compositions and methods of use

Described herein are compounds useful in the modulation of blood uric acid levels, formulations containing them and methods of using them. In some embodiments, the compounds described herein are used in the treatment or prevention of disorders related to aberrant levels of uric acid.. ... Ardea Biosciences Inc

Derivatives of n-(arylamino) sulfonamides as inhibitors of mek

This invention concerns n-(2-arylamino) aryl sulfonamides, which are inhibitors of mek and are useful in treatment of cancer and other hyperproliferative diseases.. . ... Ardea Biosciences Inc








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