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Recent patent applications related to Ardian Inc. Ardian Inc is listed as an Agent/Assignee. Note: Ardian Inc may have other listings under different names/spellings. We're not affiliated with Ardian Inc, we're just tracking patents.

ARCHIVE: New 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 | Company Directory "A" | Ardian Inc-related inventors


Catheter apparatuses for modulation of nerves in communication with pulmonary system and associated systems and methods

Devices and systems for the selective positioning of an intravascular neuromodulation device are disclosed herein. Such systems can include, for example, an elongated shaft and a therapeutic assembly carried by a distal portion of the elongated shaft. ... Ardian Inc

Helical push wire electrode

Helical push wire electrodes are provided. The electrodes may create a continuous helical lesion. ... Ardian Inc

Methods for therapeutic renal denervation

Methods for therapeutic renal denervation are disclosed herein. One aspect of the present application, for example, is directed to methods that block, reduce and/or inhibit renal sympathetic nerve activity to achieve a reduction in central sympathetic tone. ... Ardian Inc

Methods and devices for localized disease treatment by ablation

Provided herein are methods, systems, and devices for increasing heat shock protein expression and treating conditions for which increased heat shock protein expression is expected to be beneficial using thermal ablation.. . ... Ardian Inc

Neuromodulation devices for delivering neuromodulation energy to proximal vascular portions and distal vascular portions and associated systems and methods

Neuromodulation devices for delivering neuromodulation therapy to distal vascular portions and proximal vascular portions and associated systems and methods. A neuromodulation device can include an elongated shaft having a proximal portion and a distal portion, each portion being sized and shaped for simultaneous positioning and deployment within respective proximal and distal vascular portions of a human vasculature. ... Ardian Inc

Catheter apparatuses, systems, and methods for renal neuromodulation

Catheter apparatuses, systems, and methods for achieving renal neuromodulation by intravascular access are disclosed herein. One aspect of the present application, for example, is directed to apparatuses, systems, and methods that incorporate a catheter treatment device comprising an elongated shaft. ... Ardian Inc

Renal neuromodulation methods and systems for treatment of hyperaldosteronism

Methods for treating hyperaldosteronism with therapeutic renal neuromodulation and associated systems and methods are disclosed herein. One aspect of the present technology, for example, is directed to methods that at least partially inhibit sympathetic neural activity in renal nerves proximate a renal blood vessel of a human patient. ... Ardian Inc

Catheter-based devices and associated methods for immune system neuromodulation

Catheter-based devices and associated methods for immune system neuromodulation of human patients are disclosed herein. One aspect of the present technology is directed to methods of treating a human patient diagnosed with an immune system condition. ... Ardian Inc

Methods and systems for optimizing perivascular neuromodulation therapy using computational fluid dynamics

Methods and systems for optimizing perivascular neuromodulation therapy using computational fluid dynamics. Digital data regarding three-dimensional imaging of a target blood vessel and corresponding hemodynamic data are inputs to generating a computational fluid dynamics (cfd) model. ... Ardian Inc

Methods and apparatus for intravascularly-induced neuromodulation

Methods and apparatus are provided for intravascularly-induced neuromodulation using a pulsed electric field, e.g., to effectuate irreversible electroporation or electrofusion, necrosis and/or inducement of apoptosis, alteration of gene expression, changes in cytokine upregulation, etc., in target neural fibers. In some embodiments, the intravascular pef system comprises a catheter having a pair of bipolar electrodes for delivering the pef, with a first electrode positioned on a first side of an impedance-altering element and a second electrode positioned on an opposing side of the impedance-altering element. ... Ardian Inc

Renal neuromodulation methods and devices for treatment of polycystic kidney disease

Methods for treating polycystic kidney disease with therapeutic renal neuromodulation and associated systems and methods are disclosed herein. One aspect of the present technology is directed to methods that at least partially inhibit sympathetic neural activity in nerves proximate a renal artery of a kidney of a patient. ... Ardian Inc

Methods and apparatus for performing a non-continuous circumferential treatment of a body lumen

Methods and apparatus are provided for non-continuous circumferential treatment of a body lumen. Apparatus may be positioned within a body lumen of a patient and may deliver energy at a first lengthwise and angular position to create a less-than-full circumferential treatment zone at the first position. ... Ardian Inc

Spiral electrode for neuromodulation therapy

Catheters having spiral electrodes and methods for their use in neuromodulation therapy. A therapeutic assembly is disposed at a distal portion of a neuromodulation catheter and is adapted to be located at a target location within a target blood vessel of a human patient. ... Ardian Inc

Multi-electrode catheter assemblies for renal neuromodulation and associated systems and methods

Catheter apparatuses, systems, and methods for achieving renal neuromodulation by intravascular access are disclosed herein. One aspect of the present technology, for example, is directed to a treatment device having a multi-electrode array configured to be delivered to a renal blood vessel. ... Ardian Inc

03/22/18 / #20180078758

Methods and apparatus for bilateral renal neuromodulation

Methods and apparatus are provided for bilateral renal neuromodulation, e.g., via a pulsed electric field, via a stimulation electric field, via localized drug delivery, via high frequency ultrasound, via thermal techniques, etc. Such neuromodulation may effectuate irreversible electroporation or electrofusion, necrosis and/or inducement of apoptosis, alteration of gene expression, action potential attenuation or blockade, changes in cytokine up-regulation and other conditions in target neural fibers. ... Ardian Inc

03/08/18 / #20180064907

Catheters with enhanced flexibility and associated devices, systems, and methods

A neuromodulation catheter includes an elongate shaft and a neuromodulation element. The shaft includes two or more first cut shapes and two or more second cut shapes along a helical path extending around a longitudinal axis of the shaft. ... Ardian Inc

02/15/18 / #20180042535

Monitoring of neuromodulation using biomarkers

Provided herein are methods, devices, compositions, and kits for monitoring neuromodulation efficacy based on changes in the level or activity of one or more target biomarkers.. . ... Ardian Inc

02/01/18 / #20180028256

Devices, systems and methods for evaluation and feedback of neuromodulation treatment

The present disclosure relates to devices, systems and methods for evaluating the success of a treatment applied to tissue in a patient, such as a radio frequency ablative treatment used to neuromodulate nerves associated with the renal artery. A system monitors parameters or values generated during the course of a treatment. ... Ardian Inc

01/25/18 / #20180021574

Methods and apparatus for multi-vessel renal neuromodulation

Methods and apparatus are provided for multi-vessel neuromodulation, e.g., via a pulsed electric field. Such multi-vessel neuromodulation may effectuate irreversible electroporation or electrofusion, necrosis and/or inducement of apoptosis, alteration of gene expression, action potential attenuation or blockade, changes in cytokine up-regulation and other conditions in target neural fibers. ... Ardian Inc

01/25/18 / #20180021542

Packaging for catheter treatment devices and associated devices, systems, and methods

Packaging for catheter treatment devices, such as catheters including multi-electrode arrays, are disclosure herein. In one embodiment, for example, a catheter package assembly comprises a tray, a lid, and a coiled sheath disposed in the tray. ... Ardian Inc

12/21/17 / #20170361100

Methods and apparatus for renal neuromodulation

Methods and apparatus are provided for renal neuromodulation using a pulsed electric field to effectuate electroporation or electrofusion. It is expected that renal neuromodulation (e.g., denervation) may, among other things, reduce expansion of an acute myocardial infarction, reduce or prevent the onset of morphological changes that are affiliated with congestive heart failure, and/or be efficacious in the treatment of end stage renal disease. ... Ardian Inc

12/14/17 / #20170354461

Catheter apparatuses for modulation of nerves in communication with the pulmonary system and associated systems and methods

Devices and systems for the selective positioning of an intravascular neuromodulation device are disclosed herein. Such systems can include, for example, an elongated shaft and a therapeutic assembly carried by a distal portion of the elongated shaft. ... Ardian Inc

12/07/17 / #20170348050

Methods and apparatus for monopolar renal neuromodulation

Methods and apparatus are provided for monopolar neuromodulation, e.g., via a pulsed electric field. Such monopolar neuromodulation may effectuate irreversible electroporation or electrofusion, necrosis and/or inducement of apoptosis, alteration of gene expression, action potential attenuation or blockade, changes in cytokine up-regulation and other conditions in target neural fibers. ... Ardian Inc

12/07/17 / #20170347954

Methods for assessing efficacy of renal neuromodulation and associated systems and devices

Provided herein are methods, devices and compositions for assessing neuromodulation efficacy based on changes in the level of one or more biomarkers in plasma or urine collected from a human subject following a renal neuromodulation procedure.. . ... Ardian Inc

11/23/17 / #20170333126

Ovarian neuromodulation and associated systems and methods

Methods for treating polycystic ovary syndrome with therapeutic ovarian neuromodulation and associated systems and methods are disclosed herein. Polycystic ovary syndrome can be associated, for example, with a condition including at least one of oligo/amenorrhea, infertility, hirsutism, obesity, metabolic syndrome, insulin resistance, and increased cardiovascular risk profile. ... Ardian Inc

11/16/17 / #20170326363

Methods and apparatus for renal neuromodulation

Methods and apparatus are provided for renal neuromodulation using a pulsed electric field to effectuate electroporation or electrofusion. It is expected that renal neuromodulation (e.g., denervation) may, among other things, reduce expansion of an acute myocardial infarction, reduce or prevent the onset of morphological changes that are affiliated with congestive heart failure, and/or be efficacious in the treatment of end stage renal disease. ... Ardian Inc

11/16/17 / #20170325733

Systems and methods for assessing sympathetic nervous system tone for neuromodulation therapy

Systems and methods for assessing sympathetic nervous system (sns) tone for renal neuromodulation therapy are disclosed herein. A system configured in accordance with embodiments of the present technology can include, for example, a detector attached to or implanted in a patient and a receiver communicatively coupled to the detector. ... Ardian Inc

11/09/17 / #20170319853

Endovascular nerve monitoring devices and associated systems and methods

Endovascular nerve monitoring devices and associated systems and methods are disclosed herein. A nerve monitoring system configured in accordance with a particular embodiment of the present technology can include a shaft having a proximal portion and a distal portion and a nerve monitoring assembly at the distal portion. ... Ardian Inc

11/09/17 / #20170319273

Apparatus, systems, and methods for achieving intravascular, thermally-induced renal neuromodulation

Apparatus, systems, and methods for achieving thermally-induced renal neuromodulation by intravascular access are disclosed herein. One aspect of the present application, for example, is directed to apparatuses, systems, and methods that incorporate a treatment device comprising an elongated shaft. ... Ardian Inc

11/09/17 / #20170319272

Apparatus, systems, and methods for achieving intravascular, thermally-induced renal neuromodulation

Apparatus, systems, and methods for achieving thermally-induced renal neuromodulation by intravascular access are disclosed herein. One aspect of the present application, for example, is directed to apparatuses, systems, and methods that incorporate a treatment device comprising an elongated shaft. ... Ardian Inc

11/09/17 / #20170319271

Apparatus, systems, and methods for achieving intravascular, thermally-induced renal neuromodulation

Apparatus, systems, and methods for achieving thermally-induced renal neuromodulation by intravascular access are disclosed herein. One aspect of the present application, for example, is directed to apparatuses, systems, and methods that incorporate a treatment device comprising an elongated shaft. ... Ardian Inc

09/21/17 / #20170265937

Renal neuromodulation for treatment of patients

A method and apparatus for treatment of heart failure, hypertension and renal failure by stimulating the renal nerve. The goal of therapy is to reduce sympathetic activity of the renal nerve. ... Ardian Inc

09/14/17 / #20170258522

Catheter apparatuses, systems, and methods for renal neuromodulation

Catheter apparatuses, systems, and methods for achieving renal neuromodulation by intravascular access are disclosed herein. One aspect of the present application, for example, is directed to apparatuses, systems, and methods that incorporate a catheter treatment device comprising an elongated shaft. ... Ardian Inc

08/31/17 / #20170245926

Methods for therapeutic renal neuromodulation

Methods and apparatus are provided for treating hypertension, e.g., via a pulsed electric field, via a stimulation electric field, via localized drug delivery, via high frequency ultrasound, via thermal techniques, etc. Such neuromodulation may effectuate irreversible electroporation or electrofusion, necrosis and/or inducement of apoptosis, alteration of gene expression, action potential attenuation or blockade, changes in cytokine up-regulation and other conditions in target neural fibers. ... Ardian Inc

08/31/17 / #20170245925

Methods for therapeutic renal denervation

Methods for therapeutic renal denervation are disclosed herein. One aspect of the present application, for example, is directed to methods that block, reduce and/or inhibit renal sympathetic nerve activity to achieve a reduction in central sympathetic tone. ... Ardian Inc

08/24/17 / #20170239480

Methods and apparatus for bilateral renal neuromodulation

Methods and apparatus are provided for bilateral renal neuromodulation, e.g., via a pulsed electric field, via a stimulation electric field, via localized drug delivery, via high frequency ultrasound, via thermal techniques, etc. Such neuromodulation may effectuate irreversible electroporation or electrofusion, necrosis and/or inducement of apoptosis, alteration of gene expression, action potential attenuation or blockade, changes in cytokine up-regulation and other conditions in target neural fibers. ... Ardian Inc

08/17/17 / #20170232275

Methods for therapeutic renal neuromodulation

Methods and apparatus are provided for treating hypertension, e.g., via a pulsed electric field, via a stimulation electric field, via localized drug delivery, via high frequency ultrasound, via thermal techniques, etc. Such neuromodulation may effectuate irreversible electroporation or electrofusion, necrosis and/or inducement of apoptosis, alteration of gene expression, action potential attenuation or blockade, changes in cytokine up-regulation and other conditions in target neural fibers. ... Ardian Inc

08/03/17 / #20170215794

Systems and methods for monitoring and evaluating neuromodulation therapy

Systems and methods for informing and evaluating neuromodulation therapy are disclosed herein. A system configured in accordance with embodiments of the present technology can include, for example, a guidewire having a proximal portion, a distal portion configured to be positioned at a target site in a blood vessel of a human patient, and a sensing element positioned along the distal portion. ... Ardian Inc

07/20/17 / #20170202617

Methods for renal neuromodulation via neuromodulatory agents

Methods and apparatus are provided for thermally-induced renal neuromodulation. Thermally-induced renal neuromodulation may be achieved via direct and/or via indirect application of thermal energy to heat or cool neural fibers that contribute to renal function, or of vascular structures that feed or perfuse the neural fibers. ... Ardian Inc

07/20/17 / #20170202500

Biomarker sampling in the context of neuromodulation devices, systems, and methods

Methods for treating a patient using therapeutic renal neuromodulation and associated devices, systems, and methods are disclosed herein. One aspect of the present technology is directed to biomarker sampling in the context of neuromodulation devices, systems, and methods. ... Ardian Inc

05/11/17 / #20170128129

Low profile catheter assemblies and associated systems and methods

Catheters including elements configured to deliver energy to nerves at or near a treatment location within a body lumen. A treatment assembly is transformable between a low-profile delivery configuration wherein a pair of electrodes are in a staggered arrangement relative to each other along the longitudinal axis, and an expanded deployed configuration wherein the pair of electrodes is aligned along an electrode axis that is orthogonal relative to the longitudinal axis.. ... Ardian Inc

05/11/17 / #20170127987

Monitoring of neuromodulation using biomarkers

Provided herein are methods, devices, compositions, and kits for monitoring neuromodulation efficacy based on changes in the level or activity of one or more target biomarkers.. . ... Ardian Inc

05/04/17 / #20170119463

Multi-electrode apposition judgment using pressure elements

Apparatus and methods for determining positioning of a energy delivery element include deploying a energy delivery element at a treatment site proximal to a vessel wall; using a multi-region pressure sensing apparatus to sense pressures applied in a plurality of directions about the energy delivery element; and determining an orientation of the energy delivery element based on the pressures measured in the plurality of directions about the energy delivery element.. . ... Ardian Inc

04/06/17 / #20170095679

Catheter-based devices and associated methods for immune system neuromodulation

Catheter-based devices and associated methods for immune system neuromodulation of human patients are disclosed herein. One aspect of the present technology is directed to methods of treating a human patient diagnosed with an immune system condition. ... Ardian Inc

03/23/17 / #20170080230

Methods for renal neuromodulation

Methods and apparatus are provided for renal neuromodulation using a pulsed electric field to effectuate electroporation or electrofusion. It is expected that renal neuromodulation (e.g., denervation) may, among other things, reduce expansion of an acute myocardial infarction, reduce or prevent the onset of morphological changes that are affiliated with congestive heart failure, and/or be efficacious in the treatment of end stage renal disease. ... Ardian Inc

03/23/17 / #20170080214

Methods and apparatus for bilateral renal neuromodulation

Methods and apparatus are provided for bilateral renal neuromodulation, e.g., via a pulsed electric field, via a stimulation electric field, via localized drug delivery, via high frequency ultrasound, via thermal techniques, etc. Such neuromodulation may effectuate irreversible electroporation or electrofusion, necrosis and/or inducement of apoptosis, alteration of gene expression, action potential attenuation or blockade, changes in cytokine up-regulation and other conditions in target neural fibers. ... Ardian Inc

03/09/17 / #20170065337

Methods for catheter-based renal neuromodulation

Methods and apparatus are provided for monopolar neuromodulation, e.g., via a pulsed electric field. Such monopolar neuromodulation may effectuate irreversible electroporation or electrofusion, necrosis and/or inducement of apoptosis, alteration of gene expression, action potential attenuation or blockade, changes in cytokine up-regulation and other conditions in target neural fibers. ... Ardian Inc

03/09/17 / #20170065336

Methods for therapeutic renal neuromodulation

Methods and apparatus are provided for treating hypertension, e.g., via a pulsed electric field, via a stimulation electric field, via localized drug delivery, via high frequency ultrasound, via thermal techniques, etc. Such neuromodulation may effectuate irreversible electroporation or electrofusion, necrosis and/or inducement of apoptosis, alteration of gene expression, action potential attenuation or blockade, changes in cytokine up-regulation and other conditions in target neural fibers. ... Ardian Inc

03/02/17 / #20170056619

Catheters with enhanced flexibility and associated devices, systems, and methods

A neuromodulation catheter includes an elongate shaft and a neuromodulation element. The shaft includes two or more first cut shapes and two or more second cut shapes along a helical path extending around a longitudinal axis of the shaft. ... Ardian Inc

03/02/17 / #20170056087

Neuromodulation cryotherapeutic devices and associated systems and methods

Neuromodulation cryotherapeutic devices and associated systems and methods are disclosed herein. A cryotherapeutic device configured in accordance with a particular embodiment of the present technology can include an elongated shaft having distal portion and a supply lumen along at least a portion of the shaft. ... Ardian Inc

02/23/17 / #20170049512

Multi-electrode catheter assemblies for renal neuromodulation and associated systems and methods

Catheter apparatuses, systems, and methods for achieving renal neuromodulation by intravascular access are disclosed herein. One aspect of the present technology, for example, is directed to a treatment device having a multi-electrode array configured to be delivered to a renal blood vessel. ... Ardian Inc

01/26/17 / #20170021170

Methods and apparatus for multi-vessel renal neuromodulation

Methods and apparatus are provided for multi-vessel neuromodulation, e.g., via a pulsed electric field. Such multi-vessel neuromodulation may effectuate irreversible electroporation or electrofusion, necrosis and/or inducement of apoptosis, alteration of gene expression, action potential attenuation or blockade, changes in cytokine up-regulation and other conditions in target neural fibers. ... Ardian Inc

01/26/17 / #20170020597

Devices, systems and methods for evaluation and feedback of neuromodulation treatment

The present disclosure relates to devices, systems and methods for evaluating the success of a treatment applied to tissue in a patient, such as a radio frequency ablative treatment used to neuromodulate nerves associated with the renal artery. A system monitors parameters or values generated during the course of a treatment. ... Ardian Inc

01/19/17 / #20170014178

Methods and apparatus for pulsed electric field neuromodulation via an intra-to-extravascular approach

Methods and apparatus are provided for pulsed electric field neuromodulation via an intra-to-extravascular approach, e.g., to effectuate irreversible electroporation or electrofusion, necrosis and/or inducement of apoptosis, alteration of gene expression, changes in cytokine upregulation and other conditions in target neural fibers. In some embodiments, the itev pef system comprises an intravascular catheter having one or more electrodes configured for intra-to-extravascular placement across a wall of patient's vessel into proximity with target neural fibers. ... Ardian Inc

01/19/17 / #20170014177

Methods and systems for thermally-induced renal neuromodulation

Methods and system are provided for thermally-induced renal neuromodulation. Thermally-induced renal neuromodulation may be achieved via direct and/or via indirect application of thermal energy to heat or cool neural fibers that contribute to renal function, or of vascular structures that feed or perfuse the neural fibers. ... Ardian Inc

01/12/17 / #20170007325

Microwave catheter apparatuses, systems, and methods for renal neuromodulation

Microwave catheter apparatuses, systems, and methods for achieving renal neuromodulation by intravascular access are disclosed herein. One aspect of the present application, for example, is directed to apparatuses, systems, and methods that incorporate a catheter treatment device comprising an elongated shaft. ... Ardian Inc

01/12/17 / #20170007320

Renal neuromodulation for treatment of patients

A method and apparatus for treatment of heart failure, hypertension and renal failure by stimulating the renal nerve. The goal of therapy is to reduce sympathetic activity of the renal nerve. ... Ardian Inc

01/12/17 / #20170007319

Renal neuromodulation for treatment of patients

A method and apparatus for treatment of heart failure, hypertension and renal failure by stimulating the renal nerve. The goal of therapy is to reduce sympathetic activity of the renal nerve. ... Ardian Inc








ARCHIVE: New 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009



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