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Biontech Ag patents


Recent patent applications related to Biontech Ag. Biontech Ag is listed as an Agent/Assignee. Note: Biontech Ag may have other listings under different names/spellings. We're not affiliated with Biontech Ag, we're just tracking patents.

ARCHIVE: New 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 | Company Directory "B" | Biontech Ag-related inventors


Recombinant vaccines and use thereof

The present invention relates to fusion molecules of antigens, the nucleic acids coding therefor and the use of such fusion molecules and nucleic acids. In particular, said invention relates to fusion molecules, comprising an antigen and the trans-membrane region and cytoplasmic region of a mhc molecule and/or the cytoplasmic region of a mhc or a snare molecule.. ... Biontech Ag

Identification of surface-associated antigens for tumor diagnosis and therapy

The invention relates to the identification of gene products that are the result of tumor-associated expression and the nucleic acids encoding the same. The invention also relates to the therapy and diagnosis of diseases wherein these gene products are the result of an aberrant tumor-associated expression. ... Biontech Ag

Single-chain tnf ligand family molecules and fusion proteins and derivatives thereof

The present invention relates to a polypeptide comprising a component a with at least three tumor necrosis factor (tnf) homology domains of tnf-ligand family members (thd) in which c-terminal and n-terminal reference points are defined by consensus sequences and which are connected through short stretches of additional c-terminal and/or n-terminal amino acids of the thd or variants thereof, and a component b comprising a dimerization domain. Further, the present invention relates to a polypeptide comprising at least three thds in which c-terminal and n-terminal reference points are defined by consensus sequences and which are connected through short stretches of additional c-terminal and/or n-terminal amino acids of the thd or variants thereof. ... Biontech Ag

Compositions and methods for diagnosis and treatment of cancer

The present invention relates to the diagnosis and treatment of cancerous diseases, in particular cancerous diseases expressing seprase (fap-alpha; fibroblast activation protein alpha). More particularly, the invention concerns peptides targeting seprase.. ... Biontech Ag

Particles comprising single stranded rna and double stranded rna for immunomodulation

The present invention relates to chimeric particles comprising single stranded rna (ssrna), double stranded rna (dsrna) and at least one cationic agent, a pharmaceutical composition containing said particles and to a method of producing the same. The particles of the present invention are particularly useful as an immunostimulating medicament with a superlative pattern of immunostimulation.. ... Biontech Ag

Particles comprising protamine and rna in combination with endosome destabilizing agents

The present invention relates to particles comprising protamine, rna and at least one endosome destabilizing agent, to methods of their production and to pharmaceutical compositions or kits containing the particles. It further relates to particles comprising protamine and rna for use in methods of treatment or prevention of diseases and to kits comprising such particles together with at least one endosome destabilizing agent.. ... Biontech Ag

Stabilised formulations of rna

The present invention relates to stable low-salt aqueous formulations of particles comprising a polycation, preferably protamine, and rna, which formulations are preferably isotonic, to pharmaceutical compositions or kits comprising such formulations and to their use in medicine. It further relates to methods for preparing the formulations of the invention and to methods for physically stabilizing particles comprising a polycation, preferably protamine, and rna.. ... Biontech Ag

Tumor vaccination involving a humoral immune response against self-proteins

The present invention relates to tumor immunotherapy, in particular to tumor vaccination, using chimeric proteins comprising all or a portion of a hepatitis b virus core antigen protein and an amino acid sequence comprising an epitope derived from the extracellular portion of a tumor-associated antigen. In particular, the present invention provides virus-like particles comprising said chimeric proteins, which are useful for eliciting a humoral immune response in a subject against the tumor-associated antigen, in particular against cells carrying said tumor-associated antigen on their surface, wherein the tumor-associated antigen is a self-protein in said subject.. ... Biontech Ag

Identification of surface-associated antigens for tumor diagnosis and therapy

The invention relates to identifying tumor-associated genetic products and encoding nucleic acids thereof. A therapy and diagnosis of diseases in which the tumor-associated genetic products are aberrantly expressed, proteins, polypeptides and peptides which are expressed in association with tumor and the encoding nucleic acids for said proteins, polypeptides and peptides are also disclosed.. ... Biontech Ag

Modification of rna, producing an increased transcript stability and translation efficiency

It was the object of the present invention to provide rna with increased stability and translation efficiency and means for obtaining such rna. It should be possible to obtain increased grades of expression by using said rna in gene therapy approaches.. ... Biontech Ag








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