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Blanchette Rockefeller Neurosciences Institute patents

Recent patent applications related to Blanchette Rockefeller Neurosciences Institute. Blanchette Rockefeller Neurosciences Institute is listed as an Agent/Assignee. Note: Blanchette Rockefeller Neurosciences Institute may have other listings under different names/spellings. We're not affiliated with Blanchette Rockefeller Neurosciences Institute, we're just tracking patents.

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Compositions and methods to treat niemann-pick disease

The present disclosure is directed to compositions comprising bryostatin-1, and methods comprising administering a composition comprising bryostatin-1, to treat niemann-pick type c in a subject in need thereof.. . ... Blanchette Rockefeller Neurosciences Institute

Alzheimer's disease-specific alterations of the erk1/erk2 phosphorylation ratio-alzheimer's disease-specific molecular biomarkers (adsmb)

The present invention relates to methods of diagnosing alzheimer's disease as well as to methods of confirming the presence or absence of alzheimer's disease in a subject. The present invention is also directed to methods of identifying a lead compound useful for the treatment of alzheimer's disease by contacting non-alzheimer's cells with an amyloid beta peptide, stimulating the cells with a protein kinase c activator, contacting the cells with a test compound, and determining the value of an alzheimer's disease-specific molecular biomarker. ... Blanchette Rockefeller Neurosciences Institute

Convergence of aggregation rate with validated peripheral diagnostic for alzheimer's disease

The present disclosure describes diagnostics for alzheimer's disease based on the discovery of an increased aggregation rate with increasing cell density in cells from alzheimer-disease patients versus controls. The aggregation rate was cross-validated with two more mature assays: ad-index and morphology diagnostic assays. ... Blanchette Rockefeller Neurosciences Institute

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