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Bruker Daltonik Gmbh patents

Recent patent applications related to Bruker Daltonik Gmbh. Bruker Daltonik Gmbh is listed as an Agent/Assignee. Note: Bruker Daltonik Gmbh may have other listings under different names/spellings. We're not affiliated with Bruker Daltonik Gmbh, we're just tracking patents.

ARCHIVE: New 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 | Company Directory "B" | Bruker Daltonik Gmbh-related inventors

Gating element in ion mobility spectrometers

The invention relates to a gating element for switching or modulating the ion current in ion mobility spectrometers, particularly in miniature ion mobility spectrometers (ims) operated at atmospheric pressure, where the ion current of an ion source is modulated with a continuous modulation function and the mobility spectrum is generated from the measured ion current by a correlation analysis with the modulation pattern. The invention proposes using a layered plate with apertures (apertured plate) rather than a grid (or a series of grids), said apertured plate comprising at least three conductive and two insulating (or low-conductivity) layers arranged alternately, which are firmly bonded with each other.. ... Bruker Daltonik Gmbh

Mass spectrometer with laser system for producing photons of different energies

The invention relates to mass spectrometers with optically pumped lasers, whose laser light can be used for ionization by laser desorption, for the fragmentation of ions by photodissociation (pd), for the initiation of ion reactions, and for other purposes. The invention provides a laser system for a mass spectrometer, with which at least two laser beams of different wavelengths can be generated for use at different points along an ion path from an ion source to an ion detector in the mass spectrometer.. ... Bruker Daltonik Gmbh

Device and method for the preparation of samples for ionization by laser desorption in a mass spectrometer

Presented is a device for the preparation of samples for ionization by laser desorption, especially maldi, that comprises a sample support assembly with a surface which has an array of sites for holding substances, and an outer contour surrounding the sample site array, and a flat cover which can be placed flush on or over the surrounding outer contour such that a shielded gas compartment is formed between the cover and the surface, said cover having an array of apertures arranged such that each aperture comes to rest over a corresponding sample site. A gas transport system is also provided on the assembly and cover, which serves to introduce a protective gas into the shielded gas compartment between cover and surface so that a protective gas atmosphere is generated in the gas compartment to protect the substances on the sample sites against atmospheric influences. ... Bruker Daltonik Gmbh

Low dead-volume connector for fluid chromatography

The invention generally relates to a low dead-volume connector for fluid chromatography, such as liquid chromatography and gas chromatography, having a female assembly including a receiving member being designed and configured to receive, and releasably interlock with, a male assembly. The connector is particularly suited for high performance liquid chromatography (hplc) applications.. ... Bruker Daltonik Gmbh

Suppressing harmonic signals in ion cyclotron resonance mass spectrometry

The invention relates to reducing harmonic signals in ft-icr spectra. Since harmonic signals in quadrupolar 2ω-detection can be more abundant for the same ion motion in the icr cell as compared to harmonic signals in classical dipolar 1ω-detection, they could hitherto not be reduced to satisfactory levels by any known method, such as gated deflection during ion introduction into, and correcting for an offset electric field axis in the icr cell. ... Bruker Daltonik Gmbh

Analysis of isomers in tims-q-q-tof mass spectrometers

The invention relates to methods for the detailed analysis of ion mixtures from complex mixtures of organic substances in time-of-flight mass spectrometers which are equipped with a trapped ion mobility spectrometer, a quadrupole mass selector and a fragmentation cell. The invention proposes to analyze ion signals of a first mass mobility map, fragment ion spectra and the identifications of the associated substances as to whether ion mixtures not resolved according to mass and mobility, for example from isomers or isobars, are possibly present, and to subsequently measure the ion signals of interest with method parameters which allow the ion species to be measured separately by means of high mobility resolution.. ... Bruker Daltonik Gmbh

Trapped ion mobility spectrometer with high ion storage capacity

The invention is related to a trapped ion mobility spectrometer (tims device) and proposes to use higher order (order n>2) linear multipole rf systems to accumulate and analyze ions at an electric dc field barrier, either pure higher order rf multipole systems or multipole rf systems with transitions from higher order towards lower order, e.g. From a linear octopolar rf system (n=4) to a linear quadrupole rf system (n=2) in front of the apex of the electric dc field barrier.. ... Bruker Daltonik Gmbh

Lateral introduction of ions into rf ion guides

An ion guide system includes an ion guide with pole rods, a device for laterally introducing an ion species, and a mass spectrometer for analyzing product ions of reactions between different ion species. The device is configured and positioned such that an rf field with at least two-fold rotational symmetry with respect to the axis is generated. ... Bruker Daltonik Gmbh

Normalization of mass spectra acquired by mass spectrometric imaging

Mass spectra acquired by imaging mass spectrometry (ims), in particular maldi imaging of tissue sections, are each normalized by one of: the p-norm of the mass spectrum transformed by applying an exclusion list, the p-norm of the mass spectrum transformed by square rooting the intensity values, the median of the mass spectrum, and the median absolute deviation of the noise level of the mass spectrum.. . ... Bruker Daltonik Gmbh

Spatial zoom mode for accumulative trapped ion mobility spectrometry

The invention relates to the operation of ion mobility spectrometers based on gases pushing the ions over electrical field barriers, preferably in combination with mass spectrometers, and relates to trapped ion mobility spectrometers (“tims”). The invention proposes to accumulate and to scan the ions of a selected range of mobilities by using a long and flat electric field ramp created by additional voltages. ... Bruker Daltonik Gmbh

Maldi support with magnetically held spring steel plate

The invention relates to a low-cost spring steel plate as the sample support on a dimensionally stable and precisely shaped substructure, machined from an aluminum alloy, for example, and using a pattern of embedded magnets so that said plate is removable and that a body is created overall which is suitable for use in robots, for example by giving it the dimensions of a conventional microtitration plate. The planarity of the surface onto which the (organic) samples are applied is provided within the near region by the spring steel plate itself and in the far region over the whole spring steel plate by the substructure. ... Bruker Daltonik Gmbh

Structural elucidation of intact heavy molecules and molecular complexes in mass spectrometers

The invention relates to mass spectrometric analyses of heavy molecules and molecular complexes having molecular weights sometimes well above 100,000 daltons, by collision treatment in linear rf multipole collision cells. A mixture of at least one light collision gas (<40 daltons) and at least one heavy collision gas (>80 daltons) is provided in a linear rf collision cell. ... Bruker Daltonik Gmbh

Blanking out of pulses in pulsed lasers for ldi mass spectrometers

The invention relates to optically pumped and pulsed solid-state lasers which are used in mass spectrometers in particular for ionization by matrix-assisted laser desorption (maldi) and which operate at pulse frequencies of up to 10 kilohertz or even higher. The invention proposes that, instead of interrupting the clocked sequence of the laser operation, individual light pulses or groups of light pulses are blanked out so that subsequent light pulses do not have a higher energy density, in accordance with the requirements for ldi processes. ... Bruker Daltonik Gmbh

Microbe identification by mass spectrometry and infrared spectrometry

The invention relates to a method for identifying unknown microbes in a sample, wherein a mass spectrometric determination termination down to the taxonomic level of the genus or species is supplemented by a detailed determination of a lower taxonomic level or variety by means of infrared spectrometry, using restricted reference libraries of infrared spectra. These libraries can be genus-specific, containing only infrared spectra of microbes of one genus, or species-specific, containing only infrared spectra of microbes of one species. ... Bruker Daltonik Gmbh

ARCHIVE: New 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009


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