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Cephalon Inc patents


Recent patent applications related to Cephalon Inc. Cephalon Inc is listed as an Agent/Assignee. Note: Cephalon Inc may have other listings under different names/spellings. We're not affiliated with Cephalon Inc, we're just tracking patents.

ARCHIVE: New 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 | Company Directory "C" | Cephalon Inc-related inventors


Anti-il-5 antibodies

Disclosed herein are fully human antibody molecules that immunospecifically bind to human il-5. The antibody molecules can bind to human il-5 with an equilibrium affinity constant (kd) of at least about 40 pm as determined by surface plasmon resonance.. ... Cephalon Inc

1,4-substituted piperidine derivatives

Described herein are 1,4-substituted piperidine compounds according to formula i that have demonstrated activity as fatty acid synthase inhibitors. Also described herein are pharmaceutical compositions containing the described 1,4-substituted piperidine compounds, and methods of treating diseases mediated by fatty acid synthase, by administering one or more of the compounds or pharmaceutical formulations described herein. ... Cephalon Inc

Inhalation systems, devices and methods

Digital systems, devices and methods for managing a drug therapy, such as an anti-il5 mab or anti-il5 receptor mab treatment regimen for patients suffering from severe asthma (e.g., eosinophilic asthma), are provided. The digital systems, devices and methods may include hardware and software for predicting patient responses to a long term anti-il5 mab or anti-il5 receptor mab treatment based on clinical data obtained following an initial treatment period.. ... Cephalon Inc

Use of reslizumab to treat moderate to severe eosinophilic asthma

Disclosed herein are methods of treating moderate to severe eosinophilic asthma in a patient comprising administering a therapeutically effective dose of reslizumab to the patient whose symptoms are inadequately controlled with a current asthma therapeutic and wherein the patient's blood eosinophil levels are equal to or greater than 400/μl.. . ... Cephalon Inc

Affinity chromatography wash buffer

A wash buffer comprising greater than 0 mm and less than about 500 mm arginine, greater than 0 mm and less than about 250 mm guanidine, greater than 0 mm and less than about 250 mm sodium chloride, and greater than 0 mm and less than about 50 mm of an anionic surfactant, or greater than 0% and less than about 0.25% w/v of a non-ionic surfactant. When used during affinity chromatography purification of a protein of interest, such as an antibody, the wash buffer significantly reduces the level of host cell proteins from the preparation. ... Cephalon Inc

Methods for preparing fused bicyclic 2, 4-diaminopyrimidine derivatives

The present disclosure is directed to improved methods useful for the preparation of, for example, 2-[[5-chloro-2-[[(6s)-6-[4-(2-hydroxyethyl)piperazin-1-yl]-1-methoxy-6,7,8,9-tetrahydro-5hbenzo[7]annulen-2-yl]amino]pyrimidin-4-yl]amino]-n-methyl-benzamide (cep-37440).. . ... Cephalon Inc

Crystalline forms of parp inhibitors

The present disclosure relates to crystalline forms of 4,5,6,7-tetrahydro-11-methoxy-2-[(4-methyl-1-piperazinyl)methyl]-1h-cyclopenta[a]pyrrolo[3,4-c]carbazole-1,3(2h)-dione, including salts forms and free base forms.. . ... Cephalon Inc

Antibodies that specifically bind to tl1a

. . Recombinantly expressed variant antibodies that have enhanced affinity for tl1a and enhanced potency relative to the parent antibody from which they were derived are provided. The antibodies inhibit the interaction between tl1a and the death receptor 3 (dr3). ... Cephalon Inc

Novel solid forms of bendamustine hydrochloride

Novel solid forms of bendamustine hydrochloride are described, as well as methods of their preparation and use.. . ... Cephalon Inc








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