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Chemocentryx Inc patents (2016 archive)


Recent patent applications related to Chemocentryx Inc. Chemocentryx Inc is listed as an Agent/Assignee. Note: Chemocentryx Inc may have other listings under different names/spellings. We're not affiliated with Chemocentryx Inc, we're just tracking patents.

ARCHIVE: New 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 | Company Directory "C" | Chemocentryx Inc-related inventors


Substituted anilines as ccr(4) antagonists

. . Aniline compounds are provided which bind to ccr(4) and are useful for the treatment of diseases such as allergic diseases, autoimmune diseases, graft rejection and cancer.. . ... Chemocentryx Inc

Diazole lactams

Compounds are provided that act as potent antagonists of the ccr1 receptor, and have in vivo anti-inflammatory activity. The compounds are diazole lactam derivatives and are useful in pharmaceutical compositions, methods for the treatment of ccr1-mediated disease, and as controls in assays for the identification of competitive ccr1 antagonists.. ... Chemocentryx Inc

Azaindazole compounds and methods of use

Compounds are provided that act as potent antagonists of the ccr1 receptor, and have in vivo anti-inflammatory activity. The compounds are generally aryl piperazine derivatives and are useful in pharmaceutical compositions, methods for the treatment of ccr1-mediated diseases, and as controls in assays for the identification of competitive ccr1 antagonists.. ... Chemocentryx Inc

Ccr6 compunds

Compounds of formula (i) are provided which are useful in the treatment of diseases or conditions modulated at least in part by ccr6:. . ... Chemocentryx Inc

C5ar antagonists

Compounds are provided that are modulators of the c5a receptor. The compounds are substituted piperidines and are useful in pharmaceutical compositions, methods for the treatment of diseases and disorders involving the pathologic activation of c5a receptors.. ... Chemocentryx Inc

Antagonists of chemokine receptors

Compounds are provided that act as potent antagonists of the ccr1 receptor, and have in vivo anti-inflammatory activity. The compounds are generally aryl piperazine derivatives and are useful in pharmaceutical compositions, methods for the treatment of ccr1-mediated diseases, and as controls in assays for the identification of competitive ccr1 antagonists.. ... Chemocentryx Inc

Diazole amides

Compounds are provided that act as potent antagonists of the ccr1 receptor, and have in vivo anti-inflammatory activity. The compounds are diazole lactam derivatives and are useful in pharmaceutical compositions, methods for the treatment of ccr1-mediated disease, and as controls in assays for the identification of competitive ccr1 antagonists.. ... Chemocentryx Inc

Combinations and methods for treating inflammatory bowel disease using a combination therapy of small molecule inhibitors of c-c chemokine receptor 9 (ccr9) and anti-alpha4beta7 integrin blocking antibodies

. . Provided herein are compositions, methods and kits for treating inflammatory bowel disease (ibd) such as crohn's disease and ulcerative colitis in a mammal in need thereof. The method include administering to a subject with ibd a combination therapy containing a therapeutically effective amount of a chemokine receptor 9 (ccr9) inhibitor compound and a therapeutically effective amount of an anti-α4β7 integrin antibody such as vedolizumab. ... Chemocentryx Inc

Processes and intermediates in the preparation of c5ar antagonists

Intermediates and methods are provided for the preparation of selected c5ar antagonist compounds.. . ... Chemocentryx Inc

Polymorphic forms of the sodium salt of 4-tert-butyl-n-[4-chloro-2-(1-oxy-pyridine-4-carbonyl)-phenyl]-benzenesulfonamide

Disclosed are novel novel polymorphic solvated and desolvated forms of the sodium salt of 4-tert-butyl-n-[chloro-2-(1-oxy-pyridine-4-carbonyl-phenyl]-benzenesulfonamide. One embodiment of the present invention is directed to a crystalline sodium salt of 4-tert-butyl-n-[4-chloro-2-(1-oxy-pyridine-4-carbonyl)-phenyl]benzenesulfonamide (hereinafter “compound a-1,4-dioxane/water solvate”), wherein the crystalline form is characterized by an x-ray powder diffraction pattern comprising diffraction angles (° 28), when measured using cu ku radiation, at about 4.0, 8.1, 10.1, 14.2, 16.2, 18.6, 20.3, 24.7, 25.0, and 26.5.. ... Chemocentryx Inc

Polymorphic forms of the sodium salt of 4-tert-butyl-n-[4-chloro-2-(1-oxy-pyridine-4-carbonyl)-phenyl]-benzenesulfonamide

Disclosed are novel polymorphic trihydrated forms of the sodium salt of 4-tert-butyl-n-[4-chloro-2-(1-oxy-pyridine-4-carbonyl)-phenyl]benzenesulfonamide. One embodiment of the present invention is directed to a crystalline form of the sodium salt of 4-tert-butyl-n-[4-chloro-2-(1-oxy-pyridine-4-carbonyl)-25 phenyl]-benzenesulfonamide (hereinafter “compound a_crystalline trihydrate form i”), wherein the crystalline form is characterized by an x-ray powder diffraction pattern comprising diffraction angles (°28), when measured using cu ka radiation, at about 4.5, 9.0, 13.6, 13.9, 15.8, 17.8, 18.2, 18.5, 19.1, 19.9, 20a, 21.2, 22.1, 22.7, 24.3, 25.0, 25.6, 26.2, 26.8, 27.3, 27.6, 28.0, 28.8, and 30.8.. ... Chemocentryx Inc








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