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Chemocentryx Inc patents (2017 archive)


Recent patent applications related to Chemocentryx Inc. Chemocentryx Inc is listed as an Agent/Assignee. Note: Chemocentryx Inc may have other listings under different names/spellings. We're not affiliated with Chemocentryx Inc, we're just tracking patents.

ARCHIVE: New 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 | Company Directory "C" | Chemocentryx Inc-related inventors


Aryl sulfonamides

Compounds are provided that act as potent antagonists of the ccr9 receptor, and which have been further confirmed in animal testing for inflammation, one of the hallmark disease states for ccr9. The compounds are generally aryl sulfonamide derivatives and are useful in pharmaceutical compositions, methods for the treatment of ccr9-mediated diseases, and as controls in assays for the identification of ccr9 antagonists.. ... Chemocentryx Inc

Method of treating pancreatic cancer

The present disclosure describes methods of treating pancreatic cancer and limiting over-expression of oncogenes, activating tumor suppressor genes or regulating signaling proteins in patients comprising administering compounds and pharmaceutical combinations as described herein.. . ... Chemocentryx Inc

Method of treating pancreatic cancer

The present disclosure describes methods of treating pancreatic cancer and limiting over-expression of oncogenes, activating tumor suppressor genes or regulating signaling proteins in patients comprising administering compounds and pharmaceutical combinations as described herein.. . ... Chemocentryx Inc

Method of treating liver fibrosis

A method of treating liver fibrosis with ccr2 antagonists is provided. The liver fibrosis may be associated with non-alcoholic steatohepatitis (nash), non-alcoholic fatty liver disease (nafld), emerging cirrhosis, non-cirrhotic hepatic fibrosis, type 2 diabetes mellitus (t2dm) or metabolic syndrome (ms).. ... Chemocentryx Inc

Fused heteroaryl pyridyl and phenyl benzenesuflonamides as ccr2 modulators for the treatment of inflammation

Compounds are provided that act as potent antagonists of the ccr2 receptor. The compounds are generally aryl sulfonamide derivatives and are useful in pharmaceutical compositions, methods for the treatment of ccr2-mediated diseases and as controls in assays for the identification of ccr2 antagonists.. ... Chemocentryx Inc

Deuterated heteroaryl sulfonamides and their use

Compunds are provided that act as potent antagonists of the ccr2 receptor. These compounds are useful for treating inflammation, a hallmark disease for ccr2. ... Chemocentryx Inc

Reducing tumor burden by administering ccr1 antagonists in combination with pd-1 inhibitors or pd-l1 inhibitors

The present invention provides methods for reducing tumor burden, tumor growth, tumor progression, and/or metastasis in a subject suffering from a solid tumor cancer such as triple negative breast cancer. The methods include administering to a subject in need thereof a therapeutically effective amount of a pd-l1 inhibitor or a pd-1 inhibitor in combination with a small molecule chemokine receptor antagonist that blocks ccr1.. ... Chemocentryx Inc

2-oxindole compounds

. . Oxindole compounds useful for the treatment of ccr(9) mediated conditions or diseases are provided.. . ... Chemocentryx Inc

Method of treating c3 glomerulopathy

Methods of treating a human suffering from or susceptible to c3 glomerulopathy comprising administering to the human an effective amount of a c5ar antagonist are provided.. . ... Chemocentryx Inc

C5ar antagonists

Compounds are provided that are modulators of the c5a receptor. The compounds are substituted piperidines and are useful in pharmaceutical compositions, methods for the treatment of diseases and disorders involving the pathologic activation of c5a receptors.. ... Chemocentryx Inc

Heteroaryl sulfonamides and ccr2/ccr9

Compounds are provided that act as potent antagonists of the ccr2 receptor. Animal testing demonstrates that these compounds are useful for treating inflammation, a hallmark disease for ccr2. ... Chemocentryx Inc

C5ar antagonists

Compounds are provided that are modulators of the c5a receptor. The compounds are substituted piperidines and are useful in pharmaceutical compositions, methods for the treatment of diseases and disorders involving the pathologic activtation of c5a receptors.. ... Chemocentryx Inc

Fused heteroaryl pyridyl and phenyl benzenesuflonamides as ccr2 modulators for the treatment of inflammation

Compounds are provided that act as potent antagonists of the ccr2 receptor. The compounds are generally aryl sulfonamide derivatives and are useful in pharmaceutical compositions, methods for the treatment of ccr2-mediated diseases and as controls in assays for the identification of ccr2 antagonists.. ... Chemocentryx Inc

Polymorphic forms of the sodium salt of 4-tert- butyl -n-[4-chloro-2-(1-oxy-pyridine-4-carbonyl)-phenyl]-benzene sulfonamide

Disclosed are novel polymorphic solvated and desolvated forms of the sodium salt of 4-tert-butyl-n-[4-chloro-2-(1-oxy-pyridine-4-carbonyl)phenyl]-benzenesulfonamide. One embodiment of the present invention is directed to a crystalline sodium salt of 4-tert-butyl-n-[4-chloro-2-(1-oxy-pyridine-4-carbonyl)-phenyl]benzenesulfonamide (hereinafter “compound a-1,4-di-oxane/water solvate”), wherein the crystalline form is characterized by an x-ray powder diffraction pattern comprising diffraction angles (°28), when measured using cu ku radiation, at about 4.0, 8.1, 10.1, 14.2, 16.2, 18 6, 20.3, 24.7, 25.0, and 26.5.. ... Chemocentryx Inc








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