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Code 3 Inc patents


Recent patent applications related to Code 3 Inc. Code 3 Inc is listed as an Agent/Assignee. Note: Code 3 Inc may have other listings under different names/spellings. We're not affiliated with Code 3 Inc, we're just tracking patents.

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Electrochemical device

Electrochemical device 1 includes: electric storage element 5 that includes positive electrode 2, negative electrode 3 and a plurality of separators 4, positive electrode 2 and negative electrode 3 overlapping each other with separators 4 interposed therebetween; and outer container 8 that is composed of flexible film 7, outer container 8 containing electric storage element 5. Separators 4 include adhesive separator 4a and heat-resistant separator 4b whose melting point is higher than the melting point of adhesive separator 4a, and at least a part of adhesive separator 4a is welded to flexible film 7 that makes up outer container 8.. ... Code 3 Inc

Therapeutic combinations of a btk inhibitor, a pi3k inhibitor, a jak-2 inhibitor, and/or a cdk4/6 inhibitor

Therapeutic combinations of a phosphoinositide 3-kinase (pi3k) inhibitor, including pi3k inhibitors selective for the γ- and δ-isoforms and selective for both γ- and δ-isoforms (pi3k-γ,δ, pi3k-γ, and pi3k-δ, a janus kinase-2 (jak-2) inhibitor, a cyclin-dependent kinase-4/6 (cdk4/6) inhibitor, and/or a bruton's tyrosine kinase (btk) inhibitor are described. In certain embodiments, the invention includes therapeutic combinations of a cyclin-dependent kinase-4/6 (cdk4/6) inhibitor and a btk inhibitor, a pi3k-δ inhibitor and a btk inhibitor, a jak-2 and a btk inhibitor, and a jak-2, pi3k-δ, and btk inhibitor.. ... Code 3 Inc

Therapeutic combinations of a btk inhibitor, a pi3k inhibitor, a jak-2 inhibitor, and/or a bcl-2 inhibitor

Therapeutic combinations of a phosphoinositide 3-kinase (pi3k) inhibitor, including pi3k inhibitors selective for the γ- and δ-isoforms and selective for both γ- and δ-isoforms (pi3k-γ,δ, pi3k-γ, and pi3k-δ), a janus kinase-2 (jak-2) inhibitor, a bruton's tyrosine kinase (btk) inhibitor, and/or a b-cell lymphoma-2 (bcl-2) inhibitor are described. In some embodiments, the invention provides therapeutic combinations of a pi3k-δ inhibitor and a btk inhibitor, a jak-2 and a btk inhibitor, and a bcl-2 and btk inhibitor.. ... Code 3 Inc

Removing senescent cells from a mixed cell population or tissue using a phosphoinositide 3-kinase (pi3k) inhibitor

Methods are provided herein for selectively killing senescent cells and for treating senescence-associated diseases and disorders by administering a senolytic agent. Senescence-associated diseases and disorders treatable by the methods using the senolytic agents described herein include cardiovascular diseases and disorders associated with or caused by arteriosclerosis, such as atherosclerosis; idiopathic pulmonary fibrosis; chronic obstructive pulmonary disease; osteoarthritis; senescence-associated ophthalmic diseases and disorders; and senescence-associated dermatological diseases and disorders.. ... Code 3 Inc

27-28.5 ghz ka band phased array fan beam antennas and methods

The disclosed 20 dbi ksf300. A high gain 5th generation mobile network or wireless system (5g) technology fan beam antenna array offers a wide 3 db beamwidth for wide angular coverage in azimuth with most of the energy focused within 44° of the main beam. ... Code 3 Inc

Method, kit and target for multimode 3d imaging systems

A technique for acquiring target's coordinates for industrial dimensional metrology involves a target that serves both as a 2d contrast target and a 3d contact target, and a metrology tool. The target has proximal and distal surfaces, at least some of which being primarily flat and facing a common normal direction. ... Code 3 Inc

Method for the detection and characterization of a toxinogenic clostridium difficile strain

The invention relates to a cartridge for the detection and characterization of a toxinogenic clostridium difficile strain in a sample, wherein the following steps are performed, (i) a sample is provided for, (ii) in a multiplex pcr assay, (iii) the sample is analyzed with respect to the presence or absence of the cytotoxin tcdb gene, (iv) the sample is analyzed with respect to the presence or absence of one or more of the following deletions in the tcdc gene: (a) an 18 bp deletion in seq id no. 1 from nucleotide 330 to nucleotide 347, (b) a 36 bp deletion in seq id no. ... Code 3 Inc

Lithium ion secondary battery

A lithium ion secondary battery 10 includes at least one cell obtained by laminating a positive electrode 1, an electrolyte layer 2, and a negative electrode 3 in this order. The electrolyte layer 2 contains a fluoride. ... Code 3 Inc

Stereospecific process for 3-heterocyclylcycloaliphatic-1,2-diols

A process for the stereoselective synthesis of chiral 3-heterocyclyl-1,2-dihydroxy cyclohexanes is disclosed. The process involves reacting a tricyclic nitrogenous heterocycle with an allyl carbonate in the presence of a chiral palladium catalyst followed by oxidation of the olefinic bond to provide 3-heterocyclyl-1,2-dihydroxy cyclohexanes, cyclopentanes and corresponding alicyclic heterocycles. ... Code 3 Inc

Combinations and uses thereof

The present disclosure describes a pharmaceutical combination of an anti-cd19 antibody and a phosphoinositide 3-kinase inhibitor for the treatment of non-hodgkin's lymphoma, chronic lymphocytic leukemia and/or acute lymphoblastic leukemia.. . ... Code 3 Inc

Insulating material, electronic device and imaging apparatus

An electronic device includes a first electrode 31, a light emitting/light receiving layer 20 formed on the first electrode 31, and a second electrode 32 formed on the light emitting/light receiving layer 20. The light emitting/light receiving layer 20 and/or the second electrode 32 is covered by an insulating layer 40 including a metal oxide that contains, as a main component, zinc oxide, while containing, as accessory components, at least two materials selected from the group consisting of aluminum oxide, magnesium oxide, niobium oxide, titanium oxide, molybdenum oxide and hafnium oxide.. ... Code 3 Inc

Wiper assembly and connecting member for wiper assembly

There is provided a wiper assembly that includes a wiper blade and a wiper arm, and a connecting member for a wiper assembly, the wiper assembly and the connecting member being configured so that the appearance of the wiper assembly can be improved, and the work of connecting the wiper blade and the wiper arm can be facilitated. In a wiper assembly 1, a clip housing 28 is included in a blade housing section 27 of a wiper arm 2, and a wiper blade 3 and the wiper arm 2 are joined in a state where a clip member 4 is housed within the clip housing 28. ... Code 3 Inc

Wiper assembly

There is provided a wiper assembly that includes a wiper arm configured to retain a wiper blade in a state where at least a part of the wiper blade is housed within a blade housing section, the wiper assembly being configured so that a reduction in weight and a lowering of the manufacturing cost can be achieved. In a wiper assembly 1 configured to retain a wiper blade 3 by a wiper arm 2, by housing a support section 32 of the wiper blade 3 in a blade housing section 27 provided in an arm main body 23 of the wiper arm 2, the arm main body 23 is formed of metal, while the support section 32 is formed of resin. ... Code 3 Inc

Imaging device and method for manufacturing the same

An imaging device includes a plurality of light-receiving elements 10 arranged in a two-dimensional matrix shape. Each of the light-receiving elements 10 includes a first electrode 31, a photoelectric conversion layer 20, and a second electrode 32. ... Code 3 Inc

07/26/18 / #20180212660

Multi-resolution csi feedback

A method performed by a radio device 6 for channel state information (csi) feedback in a communication system 1 comprising a radio access network (ran) node 3 comprises receiving, from the ran node, information about a csi reference signal (rs) resource, a first csi type and a second csi type for feedback. The method also comprises receiving, from the ran node, a csi feedback request for csi measurement and feedback of the first csi type or the second csi type. ... Code 3 Inc

07/26/18 / #20180207154

Therapeutic combinations of a btk inhibitor, a pi3k inhibitor and/or a jak-2 inhibitor

Therapeutic combinations of a janus kinase-2 (jak-2) inhibitor, a bruton's tyrosine kinase (btk) inhibitor, and/or a phosphoinositide 3-kinase (pi3k) inhibitor, including pi3k inhibitors selective for the γ- and δ-isoforms and selective for both γ- and δ-isoforms, are described. In some embodiments, the invention provides pharmaceutical compositions comprising combinations of (1) a pi3k-δinhibitor and a btk inhibitor, (2) a jak-2 inhibitor and a btk inhibitor, or (3) a jak-2 inhibitor, pi3k-δ inhibitor, and btk inhibitor, and methods of using the pharmaceutical compositions for treating a disease, in particular a cancer.. ... Code 3 Inc

07/19/18 / #20180203280

Touch panel-attached display device and method for manufacturing touch panel-attached display device

To improve sensing sensitivity of a touch panel. A touch panel-attached display device includes an active matrix substrate 1, a counter substrate, and a liquid crystal layer. ... Code 3 Inc

07/19/18 / #20180202965

Pump electrode and reference electrode for gas sensor

On a cross sectional surface x1 of a pump electrode 3 in a gas sensor element forming a gas sensor, a noble metal area 31 having pt—au aggregations, a solid electrolyte area 32 having solid electrolyte aggregations, a mixture area in which pt—au alloy and solid electrolyte are distributed, and pores 34. The mixture area 33 is formed within a range of 30 to 90% in an overall area of the cross sectional surface x1, excepting the pores 34. ... Code 3 Inc

07/19/18 / #20180200571

Abdominal strengthening apparatus

An abdominal strengthening apparatus with rocking base. The apparatus comprises a rocking base, a supporting member, a handlebar and a foot supporting bar. ... Code 3 Inc

07/19/18 / #20180200216

Compositions for mitigating head trauma

A method for mitigating the effects of traumatic brain injury in an individual comprising is disclosed. The method includes administering an amount of a composition prior to a period wherein the traumatic brain injury is expected to occur, wherein the composition is comprised of: 300 mg and 500 milligrams (mg) of docosahexaenoic acid (dha), 50 mg/kg to 400 mg/kg (milligrams of composition per kilogram of body weight of the individual) of curcumin, and 10 mg to 100 mg of resveratrol. ... Code 3 Inc

07/12/18 / #20180194739

Methods to treat lymphoplasmacytic lymphoma

The present invention provides compounds of any one of formulae (a), (i-11), (ii), and (v) (e.g., compounds of formula (a-1)-(a-18)), and methods for treating waldenström's macroglobulinemia (wm) and other b cell neoplams in a subject using the compounds. The methods comprise administering to a subject in need thereof an effective amount of the compounds. ... Code 3 Inc

07/12/18 / #20180194622

Ammonia borane confinement in graphene oxide 3d structures

The present disclosure relates to a composite having a porous graphene oxide material (a) and ammonia borane (b), wherein the porous graphene oxide material (a) has a density of 1-100 mg/cm3, and a method for producing the same. The disclosure also relates to a hydrogen-releasing device having the disclosed composite as well as to an energy-producing device having the disclosed composite. ... Code 3 Inc

07/05/18 / #20180189982

Attribute mapping to encode and decode 3d models

Encoding and decoding of property data, such as colour values, associated with vertices forming 3d objects. From an analysis of connectivity data, a spiral-like scanning path of the vertices within the 3d model is obtained. ... Code 3 Inc

07/05/18 / #20180188212

Detector and detecting device

A detecting device 100 detects an elastic wave propagating through the air. The detecting device100 includes: a first electrode 12 that is a plate having a cantilever structure with a fixed end fx and a free end fr and that vibrates by being bent by the elastic wave; and a second electrode 32 that is a plate, that is opposed to the first electrode, and that has a predetermined distance from the first electrode. ... Code 3 Inc

07/05/18 / #20180186780

Methods to treat lymphoplasmacytic lymphoma

The present invention provides compounds of any one of formulae (i) to (v) (e.g., compounds of any one of formulae (i-1) to (i-9)), and methods for treating waldenström's macroglobulinemia (wm) and other b cell neoplams in a subject using the compounds. The methods comprise administering to a subject in need thereof an effective amount of the compounds. ... Code 3 Inc

06/28/18 / #20180184068

3d multi-aperture imaging device

A 3d multi-aperture imaging device that is, on the one hand, able to provide 3d information on a scene and, on the other hand, allows obtaining high lateral resolution and/or a wide total field of view, is described. The 3 d multi-aperture imaging device is provided with a first plurality of optical channels for projecting overlapping first partial fields of view of a total field of view on first image sensor areas of an image sensor of the 3d multi-aperture imaging device, as well as with a second plurality of optical channels for projecting overlapping second partial fields of view of the total field of view on second image sensor areas of the image sensor.. ... Code 3 Inc

06/14/18 / #20180165004

System and method for interactive 3d surgical planning and modelling of surgical implants

A method and system for interactive 3d surgical planning are provided. The method and system provide 3d visualisation and manipulation of at least one anatomical feature in response to intuitive user inputs, including gesture inputs. ... Code 3 Inc

06/07/18 / #20180158385

Interactive multiplane display system with transparent transmissive layers

A multiplane display system that includes two or more display devices provided at two or more layers. One or more of these display devices is a transparent transmissive display device. ... Code 3 Inc

05/31/18 / #20180152509

Supporting heterogeneous environments during code deployment

When servers hosting a website are under some form of deployment activity (e.g., a software update being in mid-deployment), the resources requested may not be available from all servers hosting the website. In such mid-deployment edge cases, the server would return an error message in response to the request. ... Code 3 Inc

05/31/18 / #20180147505

Composite column for use in high pressure liquid chromatography

A multi-walled tube that is useful as an analytical column in which chemical mixtures can be separated into their individual components is described. In order to be acceptable as an analytical column, the inner surface of the multi-walled tube must support effective separation, but not react chemically with or contaminate the solvent or the analyte (sample to be separated). ... Code 3 Inc

05/31/18 / #20180147172

Compositions for mitigating head trauma

A method for mitigating the effects of traumatic brain injury in an individual comprising is disclosed. The method includes administering an amount of a composition prior to a period wherein the traumatic brain injury is expected to occur, wherein the composition is comprised of: 300 mg and 500 milligrams (mg) of docosahexaenoic acid (dha), 50 mg/kg to 400 mg/kg (milligrams of composition per kilogram of body weight of the individual) of curcumin, and 10 mg to 100 mg of resveratrol. ... Code 3 Inc

05/31/18 / #20180146934

Method and apparatus for x-ray scan of occlusal dental casts

An extra-oral imaging apparatus can obtain a 3d volume image of a portion of a head of a patient. Exemplary dental apparatus and/or method embodiments can provide 3d mesh models of surfaces of the maxillary dental arch and the mandibular dental arch in a 3d volume image obtained from a single extraoral scan of physical casts of the maxillary dental arch and the mandibular dental arch in an occlusal relationship. ... Code 3 Inc

05/24/18 / #20180140585

Biomolecules involved in alzheimer's disease

The invention relates to panels of biomarkers including proteins phosphatase 1 regulatory subunit 14a and/or 2′,3′-cyclic-nucleotide 3′-phosphodiesterase and/or phosphorylated tau or fragments thereof and methods using thereof for diagnosing, staging, treating and assessing the response of a treatment for a neurocognitive disorder characterised by tau toxicity, in particular for alzheimer's disease. The present invention shows that the biomarkers disclosed herein are elevated in the brain of subjects with an advanced stage of a neurocognitive disorder (braak stage v/vi) and/or are regulated in the csf of ad subjects in comparison to cognitively affected non-ad controls; and/or regulated in response to two casein kinase 1 delta inhibitors.. ... Code 3 Inc

05/17/18 / #20180133918

Drilling apparatus and drilling method

Prior to lining a main pipe, a marker configured as a receiving coil 33 is disposed at the center 12b of a lateral pipe opening or at a position separated a predetermined distance s from the center thereof. An in-pipe robot 20 is loaded coaxially or separated by the predetermined distance with a rotatable drilling blade 31 for drilling a hole in a main pipe lining material 13 that blocks the lateral pipe opening and a transmitting coil 40 that detects a marker position. ... Code 3 Inc

05/17/18 / #20180133226

Combination of a phosphatidylinositol-3-kinase (pi3k) inhibitor and a mtor inhibitor

The invention relates to a pharmaceutical combination which comprises (a) a phosphoinositide 3-kinase inhibitor compound of formula (i) and (b) a mtor inhibitor for the treatment of a target of rapamycin (mtor) kinase dependent disease, especially a cancer disease; a pharmaceutical composition comprising such a combination; the use of such a combination for the preparation of a medicament for the treatment of a proliferative disease; a commercial package or product comprising such a combination as a combined preparation for simultaneous, separate or sequential use; and to a method of treatment of a warm-blooded animal, especially a human.. . ... Code 3 Inc

05/17/18 / #20180133223

Combination therapy with a phosphoinositide 3-kinase inhibitor with a zinc binding moiety

Or a pharmaceutically acceptable salt thereof, wherein r is hydrogen or an acyl group; and (b) a bcl-2 inhibitor; wherein the compound of formula i or pharmaceutically acceptable salt thereof and a bcl-2 inhibitor are administered in amounts which in combination are therapeutically effective. The invention further provides a pharmaceutical composition comprising a compound of formula i or a pharmaceutically acceptable salt thereof, a bcl-2 inhibitor and a pharmaceutically acceptable carrier or excipient.. ... Code 3 Inc

05/10/18 / #20180127453

2'-arabino-fluorooligonucleotide n3'˜p5' phosphoramidates: their synthesis and use

Oligonucleotides with a novel sugar-phosphate backbone containing at least one 2′-arabino-fluoronucleoside and an internucleoside 3′-nh—p(—o)(or)—o-5′ linkage, where r is a positively charged counter ion or hydrogen, and methods of synthesizing and using the inventive oligonucleotides are provided. The inventive phosphoramidate 2′-arabino-fluorooligonucleotides have a high rna binding affinity to complementary nucleic acids and are base and acid stable.. ... Code 3 Inc

05/03/18 / #20180122138

Collaborative 3d modeling system

A collaborative 3d modeling system, comprising a computer processing unit, a digital memory, and an electronic display, the computer processing unit and the digital memory configured to provide 3d model representations of a first plurality of versions of an object component for a first user, the versions being selectable along a first axis, and using the electronic display, provide a plurality of user identifications which are selectable along a second axis, wherein selecting a subsequent user causes a second plurality of said versions of said object component to be displayed on the electronic display.. . ... Code 3 Inc

05/03/18 / #20180120552

Aperture-plate drive mechanism

Provided is an aperture-plate drive mechanism including an aperture-plate open-close mechanism and a rotation mechanism for rotating the open-close mechanism. The open-close mechanism includes: drive blocks 308 fixed to a pair of aperture plates 301; a linear motion guide 306 allowing the drive blocks to move along an axis; a feed screw 302 parallel to the axis, on which a pair of helical threads proceedimg in opposite directions formed; nut members 305 each of which is provided in a manner to be engaged with one of the pair of helical threads and is prevented from rotating due to a rotation of the feed screw; an urging member 309 for pressing the drive blocks onto the nut members, respectively; and a distance adjustment member 310 placed between one drive block and the corresponding nut member, for adjusting the distance between them. ... Code 3 Inc

05/03/18 / #20180119782

Aperture-plate moving mechanism

Provided is an aperture-plate moving mechanism, including: a drive block 308 fixed to an aperture plate 301; a linear motion guide 306 for allowing the drive block to move along an axis while preventing the drive block from moving in other directions; a feed screw 302 laid in a direction of the axis; a nut member 305 having a threaded hole engaged with the feed screw, the nut member being prevented from rotating due to a rotation of the feed screw; and an urging member 309 for pressing the drive block onto the nut member in the direction of the axis. With respect to the direction of the axis, the contact portion of either the drive block or the nut member is a convex surface, while the contact portion of the other member is a concave surface having a larger radius of curvature than the convex surface.. ... Code 3 Inc

05/03/18 / #20180119232

Grading, staging, and prognosing cancer using osteopontin-c

The present disclosure provides methods and kits that can be used to determine the grade or stage of a breast or other cancer, such as a ductal carcinoma in situ (dcis). By determining the grade, stage, or aggressiveness of a cancer, appropriate therapeutic regiments can be selected and administered to the patient with the cancer. ... Code 3 Inc

05/03/18 / #20180119198

Methods, compositions and kits for high throughput kinase activity screening using mass spectrometry and stable isotopes

A mass-spectrometry-based method and substrates are provided herein for large scale kinome activity profiling directly from crude lysates using 90 chemically synthesized peptide substrates with amino acid sequences derived from known phosphoproteins. Quantification of peptide phosphorylation rates was achieved via the use of stable isotope labeled synthetic peptides. ... Code 3 Inc

05/03/18 / #20180117055

Use of phosphoinositide 3-kinase inhibitors for treatment of vascular malformations

The present disclosure relates to methods of treating a vascular malformation in a subject expressing a gain-of-function mutation in a pik3ca gene comprising administering, to the subject, an effective amount of an agent that inhibits phosphoinositide 3-kinase (“pi3k”).. . ... Code 3 Inc

04/19/18 / #20180105087

Friction module, friction hinge, and adjustable headrest including the friction module and/or friction hinge

An adjustable headrest 300 includes a guide 360 configured to be coupled to a seat, a head support 302 coupled to the guide and configured to be movable along an adjustment path relative to the seat, and a slider 370 having a surface defining a recess 373 receiving the guide such that the surface of the slider contacts a surface of the guide. The adjustment headrest further includes a retainer 390 positioned to urge the surface of the slider against the surface of the guide, thereby maintaining friction between the surface of the slider and the surface of the guide and resisting unintended movement of the slider with respect to the guide along the adjustment path. ... Code 3 Inc

04/12/18 / #20180102568

Secondary battery, method for manufacturing secondary battery, electric vehicle and electricity storage system

The secondary battery comprises: a battery element 20 having a positive electrode 30 wherein positive active material 31 are applied on both surfaces of a positive current collector 32, a negative electrode 40 wherein negative active material 41 are applied on both surfaces of a negative current collector 42, and a separator; a packaging film 10, made of a film that includes a heat-seal resin layer 13, for accommodating the battery element; wherein a melting point or a decomposition temperature of the separator is higher than a melting point of the heat-seal resin layer by 50° c. Or more; and wherein, at least a part of the active material layer 31, 41 of the positive electrode or the negative electrode and the heat-seal resin layer are heat-sealed to each other at at least one surface of the upper surface and the lower surface of the battery element.. ... Code 3 Inc

03/29/18 / #20180091803

Projection display providing additional modulation and related methods

A projection display system includes a spatial modulator that is controlled to compensate for flare in a lens of the projector. The spatial modulator increases achievable intra-frame contrast and facilitates increased peak luminance without unacceptable black levels. ... Code 3 Inc

03/29/18 / #20180090529

Solid-state image pickup device

A solid-state image pickup device 1 according to the present invention includes a semiconductor substrate 2 on which a pixel 20 composed of a photodiode 3 and a transistor is formed. The transistor comprising the pixel 20 is formed on the surface of the semiconductor substrate, a pn junction portion formed between high concentration regions of the photodiode 3 is provided within the semiconductor substrate 2 and a part of the pn junction portion of the photodiode 3 is extended to a lower portion of the transistor formed on the surface of the semiconductor substrate 2. ... Code 3 Inc

03/22/18 / #20180083288

Lithium-ion secondary battery and method of manufacturing the same

There is provided a lithium-ion secondary battery that includes a positive electrode including a sulfur-based positive active material containing at least sulfur and a negative electrode including a silicon-based negative active material containing at least silicon or a tin-based negative active material containing tin, in which lithium ions are easily implanted and moved. There is also provided a method of manufacturing the lithium-ion secondary battery. ... Code 3 Inc

03/22/18 / #20180081519

3d document editing system

A 3d document editing system and graphical user interface (gui) that includes a virtual reality and/or augmented reality device and an input device (e.g., keyboard) that implements sensing technology for detecting gestures by a user. Using the system, portions of a document can be placed at or moved to various z-depths in a 3d virtual space provided by the vr device to provide 3d effects in the document. ... Code 3 Inc

03/22/18 / #20180081060

Active continuous awareness surveillance system (acass): a multi-mode 3d lidar for diverse applications

The achievement of wide area, three dimensional imaging using a lidar sensor system is accomplished with one laser which operates using an eye safe fiber laser with very high pulse rates but very low energy per pulse.. . ... Code 3 Inc

03/22/18 / #20180079134

Process for strengthening porous 3d printed objects

A composite body includes a bound mixture and a resin. The bound mixture includes a binder and a plurality of particles. ... Code 3 Inc

03/15/18 / #20180072699

Phosphoinositide 3-kinase inhibitors

A compound of formula i: or a pharmaceutically acceptable salt thereof, wherein: r1, r2, r3, r and r6 are each independently (lq)my; r4 is h, halogen, optionally substituted aryl or optionally substituted alkyl; and; each x is independently cr7 or n. The compounds are pi3k inhibitors and therefore have potential utility in therapy.. ... Code 3 Inc

02/22/18 / #20180053945

Metal-air battery and method for producing same

An object of the present invention is to provide a metal-air battery capable of achieving high enough output (maximum power) to be applicable to use such as charging a cell phone. The metal-air battery of the present invention uses a metal as an active material of a negative electrode 30 and oxygen in the air as an active material of a positive electrode 20. ... Code 3 Inc

02/15/18 / #20180043805

Ventilated seat cushion

A seat includes one or more cushions secured to a shell. The cushions include a 3d printed lattice of repeating cells. ... Code 3 Inc

02/15/18 / #20180043240

Table game system

A table game system is provided that includes a plurality of association tables, each of which makes it possible to obtain the correlation between codes attached to shuffled playing cards and the ranks thereof, and prevents the correlation between the codes of the shuffled playing cards and the ranks thereof from being known by a person who intends to commit cheating by changing the association table used as appropriate. A card shoe apparatus 2 of the table game system of the present invention includes a barcode reader 100 that reads a barcode 3 attached to a shuffled playing card set 1s, and thereby reads a shuffled card id that can uniquely identify the shuffled playing card set 1s. ... Code 3 Inc

02/08/18 / #20180037565

Process for the preparation of 3-(3-chloro-1h-pyrazol-1-yl)pyridine

3-(3-chloro-1h-pyrazol-1-yl)pyridine is prepared by cyclizing 3-hydrazinopyridine-.dihydrochloride with a dialkyl maleate to provide an alkyl 5-oxo-2-(pyridin-3-yl)pyrazolidine-3-carboxylate, by chlorinating to provide an alkyl 3-chloro-1-(pyridin-3-yl)-4,5-dihydro-1h-pyrazole-5-carboxylate, by oxidizing to provide an alkyl 3-chloro-1-(pyridin-3-yl)-1h-pyrazole-5-carboxylate, by converting the ester to the carboxylic acid by hydrolysis to provide 3-chloro-1-(pyridin-3-yl)-1h-pyrazole-5-carboxylic acid hydrochloride, and by removing the carboxylic acid by a decarboxylation reaction.. . ... Code 3 Inc

02/01/18 / #20180030499

Electrode and manufacturing method thereof, enzyme sensor, glucose sensor and in-vivo component measuring device

In a hydrogen peroxide electrode 100 used as a working electrode 30 of an enzyme sensor 20, an intermediate layer 101 containing particles and a retentive substance for holding the particles inside the retentive substance are provided on a substrate 21, and an electrode layer 107 is provided on the intermediate layer 101. In this way, according to the hydrogen peroxide electrode 100, hydrogen peroxide can be detected with high sensitivity even when an applied voltage that is not susceptible to interference by interference substances present in the living body is used.. ... Code 3 Inc

02/01/18 / #20180030029

Process for the preparation of 3-(3-chloro-1h-pyrazol-1-yl)pyridine

3-(3-chloro-1h-pyrazol-1-yl)pyridine is prepared by cyclizing 3-hydrazinopyridine.dihydrochloride with commercially available 3-ethoxyacrylonitrile to provide 3-(3-amino-1h-pyrazol-1-yl)pyridine, and by converting the amino group to a chloro group by a sandmeyer reaction.. . ... Code 3 Inc

01/25/18 / #20180026324

Systems and methods for manufacturing stacked circuits and transmission lines

Devices and methods for manufacturing rf circuits and systems in both passive and active forms are contemplated herein. Exemplary devices include 3d electrical and mechanical structures which are created from individual slices which may be assembled to create a final functional block such as a circuit, component or a system. ... Code 3 Inc

01/18/18 / #20180017820

Pi-cell polarization switch for a three dimensional display system

Techniques are disclosed relating to the transmission of data based on a polarization of a light signal. In some embodiments, data may include 3d video data for viewing by a user. ... Code 3 Inc

01/11/18 / #20180010466

Moving blade and turbine using moving blade

A moving blade 21d is disposed in a last stage closest to a diffuser 10 among a plurality of stages of a turbine 9 including a turbine rotor 12 and a stationary body 14. The diffuser 10 is connected to an outlet side of the stationary body 14. ... Code 3 Inc

01/11/18 / #20180009826

Tricyclic heterocyclic compounds as phosphoinositide 3-kinase inhibitors

Compounds of formula (i) or a pharmaceutically acceptable salt thereof, wherein: w is o, n—h, n—(c1-c10 alkyl) or s; each x is independently ch or n; r1 is a 5 to 7-membered saturated or unsaturated, optionally substituted heterocycle containing at least 1 heteroatom selected from n or o; r2 is (lq)my; and each r3 is independently h, c1-c10 alkyl, aryl or heteroaryl, are surprisingly found to be inhibitors of pi3k-p110δ, and therefore have utility in therapy.. . ... Code 3 Inc

01/04/18 / #20180001639

Mems device, head and liquid jet device

Provided are an mems device, a head, and a liquid jet device in which substrates are inhibited from warping, so that a primary electrode and a secondary electrode can be reliably connected to each other. Included are a primary substrate 30 provided with a bump 32 including a primary electrode 34, and a secondary substrate 10 provided with a secondary electrode 91 on a bottom surface of a recessed portion 36 formed by an adhesive layer 35. ... Code 3 Inc

01/04/18 / #20180000684

Myofascial and compression release device

Described herein is a device and method for performing ischemic compression therapy to treat myofascial release. A method for performing ischemic compression therapy includes providing a device comprising two or more pressure rollers and an elastic compression band. ... Code 3 Inc

12/28/17 / #20170373468

Light emitting device and method of manufacturing the same

A light emitting device, includes a selective growth mask layer 44; a first light reflection layer 41 thinner than the selective growth mask layer 44; a laminated structure including a first compound semiconductor layer 21, an active layer 23, and a second compound semiconductor layer 22, the first compound semiconductor layer 21 being formed on the first light reflection layer 41; and a second electrode 32 formed on the second compound semiconductor layer 22, and a second light reflection layer 42, in which the second light reflection layer 42 is opposed to the first light reflection layer 41, and the second light reflection layer is not formed on an upper side of the selective growth mask layer 44.. . ... Code 3 Inc

12/21/17 / #20170362251

Phosphoinositide 3-kinase inhibitors with a zinc binding moiety

The instant application relates to deazapurines, thienopyrimidines and furopyrimidines with zinc-binding moiety based derivatives and their use in the treatment of phosphoinositide 3-kinase related diseases and disorders such as cancer. The instant application further relates to the treatment of histone deacetylase related disorders and diseases related to both histone deacetylase and phosphoinositide 3-kinase.. ... Code 3 Inc

12/21/17 / #20170361246

Composite column for use in high pressure liquid chromatography

A multi-walled tube that is useful as an analytical column in which chemical mixtures can be separated into their individual components is described. In order to be acceptable as an analytical column, the inner surface of the multi-walled tube must support effective separation, but not react chemically with or contaminate the solvent or the analyte (sample to be separated). ... Code 3 Inc

12/14/17 / #20170358711

Light emitting diode

Provided is a light emitting diode including: a columnar laminated structure 20 in which a first compound semiconductor layer 21, a light emitting layer 23 formed of a compound semiconductor, and a first portion 22a of a second compound semiconductor layer are laminated; a first electrode 31 electrically connected to the first compound semiconductor layer 21; and a second electrode 32. A second portion 22b of the second compound semiconductor layer is formed on the first portion 22a of the second compound semiconductor layer, apart from an edge portion 22a3 of the first portion 22a of the second compound semiconductor layer, the second electrode 32 is formed at least on a top surface of the second portion 22b of the second compound semiconductor layer, and light is outputted at least from the top surface 22b1 and a side surface 22b2 of the second portion 22b of the second compound semiconductor layer.. ... Code 3 Inc

12/07/17 / #20170349566

An efficient process for the synthesis of alkoxy substituted benzaldehydes

The present invention relates to the synthesis of alkoxy substituted benzaldehydes obtained from the corresponding alkoxy substituted benzenes. Alkoxy substituted benzaldehydes are products of broad commercial interest and are used as end products and intermediates in flavor and fragrance applications and pharmaceutical ingredients. ... Code 3 Inc

11/30/17 / #20170342049

Novel 1,3,5 -triazine based pi3k inhibitors as anticancer agents and a process for the preparation thereof

The present invention describes heterocyclic compounds of general formula 1 and their method of preparation thereof. The present invention describes general formula 1 which inhibits phosphoinositide 3-kinase (pi3k) and can be used as the anticancer agents.. ... Code 3 Inc

11/30/17 / #20170340641

Heterocyclylamines as pi3k inhibitors

Wherein the variables are defined herein, that modulate the activity of phosphoinositide 3-kinases (pi3ks) and are useful in the treatment of diseases related to the activity of pi3ks including, for example, inflammatory disorders, immune-based disorders, cancer, and other diseases.. . ... Code 3 Inc

11/23/17 / #20170334919

2-((4-amino-3-(3-fluoro-5-hydroxyphenyl)-1h-pyrazolo[3,4-d]pyrimidin-1 -yl)methyl)-3-(2-(trifluoro-met hyl)benzyl)quinazolin-4(3h)-one derivatives and their use as phosphoinositide 3-kinase inhibitors

And to compositions comprising the same and to the use of the compounds and to compositions of the compounds in treatment, for example in the treatment of inflammatory diseases, in particular respiratory inflammatory disease. The invention also extends to methods of making the said compounds.. ... Code 3 Inc

11/16/17 / #20170327075

Occupant restraining apparatus

‘code 3x97’ is a new and distinct lemon tree notable for its high quality seedless fruit.. . According to one embodiment, an occupant restraining apparatus includes a webbing w, a tongue 4, an airbag 20 provided along the webbing w, a bag cover 40 surrounding the airbag 20, and a webbing guide 30 through which the webbing w is passed. The webbing guide 30 extends continuously from one end to the other end of the bag cover 40. ... Code 3 Inc

11/09/17 / #20170324163

Broadband low-beam-coupling dual-beam phased array

Broadband slot-coupled stacked patch antenna elements are capable of continuous broadband operation between 1.71 ghz and 2.69 ghz. The broadband slot-coupled stacked patch antenna element includes a mid-band radiating patch, a high-band radiating patch, and a low-band resonator with coupling slots capable of resonating at low, mid, and high band frequencies. ... Code 3 Inc

11/09/17 / #20170323460

Image color data normalization and color matching system for translucent material

A shade selection program is disclosed that predicts the shade choice with the smallest ciede2000 color difference for dental composite resin restorations when given a backing and target shade. By utilizing generated regression models, a database of spectral reflectance information, and principles of kubelka-munk layering, a highly accurate shade selection program was designed. ... Code 3 Inc

11/02/17 / #20170316853

Chip resistor

Methods and systems are disclosed including a computing device configured to allow a user to view a multi-stream video from a selected angle/direction with respect to the contents of the multi-stream video, under the user's control. The multi-stream video is generated using multiple image acquisition devices (iad), such as cameras, simultaneously, consecutively, or independently filming a scene, each iad having a different position with respect to each of the other iads. To provide a chip resistor in which a resistive element can be surely protected from an external environment and which is also excellent in corrosion resistance, a chip resistor 1 is configured to include an insulating substrate 2, a pair of front electrode 3 provided on opposite end portions of a front surface of the insulating substrate 2, a pair of back electrodes 7 provided on opposite end portions of a back surface of the insulating substrate 2, a resistive element 4 provided to extend onto the two front electrodes 3, a first insulating layer 5 covering the resistive element 4, a second insulating layer 6 made of a resin material to cover the first insulating layer 5, end surface electrodes 8 establishing electrical continuity between the front electrodes 3 and the back electrodes 7, plating layers 9 covering the end surface electrodes 8, etc. Rough surface portions 6a made rougher in surface roughness than any other portion of the second insulating layer 6 are formed at opposite end portions of the second insulating layer 6. ... Code 3 Inc

11/02/17 / #20170315083

Gas sensor and gas-measuring device for detecting volatile organic compounds

A gas sensor 10 has a measuring channel 11 with a gas inlet 12 and with a gas outlet 13, at least one receptor layer 20, a reference electrode 30 and a voltage-controlled analysis unit 50. The reference electrode 30 is capacitively coupled with the receptor layer 20. ... Code 3 Inc

10/26/17 / #20170309383

Coil component and method for producing the same

A coil component 1 such as a solenoid valve is provided with a wiring part 20 formed by winding a conducting wire 4 therearound, and terminal electrodes 3a, 3b having connection terminals 16a, 16b electrically connected to the conducting wire 4. A locking piece 15a is provided on the terminal electrode 3a on a side of a wiring part for the connection terminal 16a, a starting end part of the conducting wire 4 is locked to the locking piece 15a, and the conducting wire 4 is led up in a direction reverse to a direction in which the wiring part 20 is arranged at a predetermined position, is passed into the connection terminal 16a so as to be electrically connected to the connection terminal 16a, and further led up in the direction reverse to the direction in which the wiring part 20 is arranged at a predetermined position.. ... Code 3 Inc

10/26/17 / #20170308076

Uav aerial photographing system

The present invention discloses a uav aerial photographing system having a remote control device, a uav, and a ptz camera, wherein the remote control device is used to transmit a flight instruction to the uav; wherein the uav is used to fly in any one of the following modes according to the flight instruction: mode 1: flying around a first target point with a preset radial distance; mode 2: flying a first preset distance on a straight line formed by a target point and a lens angle of the ptz camera in a direction away from the target point; mode 3: flying according to a curved preset path; mode 4: flying with a preset angle and a second preset distance kept between the uav and the remote control device; and wherein the ptz camera is used to perform photographing during flight of the uav.. . ... Code 3 Inc

10/26/17 / #20170305034

System and method of connecting two 3d printed structures

A method for forming three-dimensional (3d) printed structures is disclosed. The method may include 3d printing a first structural member including an opening to a cavity inside the first structural member; and 3d printing a second structural member including a protrusion disposed within the opening and the cavity of the first structural member.. ... Code 3 Inc

10/26/17 / #20170304279

Phosphoinositide 3-kinase inhibitor with a zinc binding moiety

Pharmaceutical compositions comprising such compounds and the use of such compounds in the treatment of phosphoinositide 3-kinase related diseases and disorders such as cancer. The instant application further relates to the treatment of histone deacetylase related disorders and diseases related to both histone deacetylase and phosphoinositide 3-kinase.. ... Code 3 Inc

09/28/17 / #20170280126

Truncated square pyramid geometry and frame packing structure for representing virtual reality video content

Techniques and systems are described for mapping 360-degree video data to a truncated square pyramid shape. A 360-degree video frame can include 360-degrees' worth of pixel data, and thus be spherical in shape. ... Code 3 Inc

09/28/17 / #20170278732

Wafer placement apparatus

A wafer placement apparatus 30 includes a ceramic substrate 32 having a wafer placement surface, a heater electrode 34 embedded in the ceramic substrate 32, and feeder rods 36 and 37 made of cu and electrically connected to the heater electrode 34 through a surface of the ceramic substrate 32 opposite the wafer placement surface. When one end and the other end of the feeder rod 36 in an unengaged state are a fixed end and a free end, respectively, and when a relationship between a stress applied to the feeder rod 36 at a position 50 mm apart from the fixed end toward the free end and a strain at the position is obtained, the stress is in a range of 5 to 10 n when the strain is 1 mm.. ... Code 3 Inc

09/28/17 / #20170277973

Multi-camera device

Apparatuses, methods and storage medium associated with multi-camera devices are disclosed herein. In embodiments, a multi-camera device may include 3 or more camera sensors disposed on a world facing side of the multi-camera device. ... Code 3 Inc

09/28/17 / #20170276110

Injector built-in ignition device, internal combustion engine, gas burner, and ignition device

The object is to provide an injector with a built-in ignition device that can achieve downsize of device as a whole without changing significantly the structure of a fuel injection device. The injector with the built-in ignition device comprises an ignition device 3 and a fuel injection device 2. ... Code 3 Inc

09/28/17 / #20170274093

Combining anti-hla-dr or anti-trop-2 antibodies with microtubule inhibitors, parp inhibitors, bruton kinase inhibitors or phosphoinositide 3-kinase inhibitors significantly improves therapeutic outcome in cancer

The present invention relates to combination therapy with drugs, such as microtubule inhibitors, parp inhibitors, bruton kinase inhibitors or pi3k inhibitors, with antibodies or immunoconjugates against hla-dr or trop-2. Where immunoconjugates are used, they preferably incorporate sn-38 or pro-2pdox. ... Code 3 Inc

09/21/17 / #20170266191

Therapeutic combination of pi3k inhibitor and a btk inhibitor

In some embodiments, the invention includes a therapeutic combination of a phosphoinositide 3-kinase (pi3k) inhibitor, including pi3k inhibitors selective for the γ- and δ-isoforms and selective for both γ- and δ-isoforms, and a bruton's tyrosine kinase (btk) inhibitor. In some embodiments, the invention includes therapeutic methods of using a btk inhibitor and a pi3k-δ inhibitor to treat solid tumor cancers by modulation of the tumor microenvironment, including macrophages, monocytes, mast cells, helper t cells, cytotoxic t cells, regulatory t cells, natural killer cells, myeloid-derived suppressor cells, regulatory b cells, neutrophils, dendritic cells, and fibroblasts.. ... Code 3 Inc

09/14/17 / #20170259391

Processing section for a floor-processing machine, adapter system for a floor-processing machine, floor-processing machine and tool therefor

The invention relates to a processing section 1 and an adapter system 10 of a floor-processing machine. The processing section 1 comprises a base body 2 with a processing side 3 and a mounting side, wherein the mounting side is arranged on the opposite side of the processing side 3 of the base body 2. ... Code 3 Inc

09/07/17 / #20170254714

Vacuum gauge and contamination diagnosis method

Provided are: a vacuum gauge that, with a simple configuration, can accurately diagnose the degree of contamination of the vacuum gauge; and a contamination diagnosis method that, with a simple process, can accurately diagnose the degree of contamination of a vacuum gauge. Provided is a cold cathode ionization vacuum gauge that has a normal operation mode and a contamination diagnosis mode, the cold cathode ionization vacuum gauge comprising: an anode 1 and a cathode 3 that are for measuring vacuum pressure in the normal operation mode; an anode 7 and the cathode 3 that are for measuring the vacuum pressure in the contamination diagnosis mode; and a controller 10 that compares the size of a current measured between the anode 7 and the cathode 3 and the size of a current measured between the anode 1 and the cathode 3.. ... Code 3 Inc

09/07/17 / #20170253401

System and method for packaging items for shipping using additive manufacturing

The method for packaging objects for shipping, which may be configured as a single all-in-one device, is carried out by scanning or selecting an item to be packaged from a catalogue and then using that information to generate a custom shipping enclosure using additive manufacturing techniques. Additive manufacturing techniques to create these custom shipping packages may include 3d printing, extrusion and sintering based processes as well as other techniques obvious to those skilled in the art. ... Code 3 Inc

08/31/17 / #20170246173

Methods and pharmaceutical compositions for treating lymphoid malignancy

The present invention provides, inter alia, methods for treating, preventing, or ameliorating the effects of a lymphoid malignancy, such as those associated with a mutated phosphatase and tensin homolog (pten) gene, or t-cell acute lymphoblastic leukemia (t-all). These methods include administering to a subject an effective amount of a phosphoinositide 3-kinase-delta (pi3kδ) inhibitor and a phosphoinositide 3-kinase-gamma (pi3kγ) inhibitor. ... Code 3 Inc

08/24/17 / #20170240932

Recombinant yeast producing 3-hydroxypropionic acid and method for producing 3-hydroxypropionic acid using the same

Provided are a recombinant yeast producing 3-hydroxypropionic acid (3-hp) and a method for producing 3-hp using the same, more particularly, a recombinant yeast producing 3-hp, comprising an exogenous aadh gene; an endogenous or exogenous acc gene; an exogenous mcr gene; and an exogenous hpdh gene, and producing 3-hp through [pyruvate acetaldehyde→acetyl-coa malonyl-coa malonate semialdehyde 3-hp] biosynthesis pathway, and a method for producing 3-hp using the same.. . ... Code 3 Inc

08/24/17 / #20170239351

Therapeutic combinations of a btk inhibitor, a pi3k inhibitor, a jak-2 inhibitor, a pd-1 inhibitor, and/or a pd-l1 inhibitor

Therapeutic compositions and methods of using the compositions, including combinations of a bruton's tyrosine kinase (btk) inhibitor, a phosphomositide 3-kinase (pi3k) inhibitor, including pi3k inhibitors selective for the γ- and δ-isoforms and selective for both y- and δ-isoforms (pi3k-γ,δ, pi3k-γ, and pi3k-δ, a programmed death 1 (pd-1) or programmed death ligand 1 (pd-l1) inhibitor, and/or a janus kinase-2 (jak-2) inhibitor are described. In certain embodiments, the invention includes therapeutic methods of using a pd-1 monoclonal antibody and a btk inhibitor. ... Code 3 Inc

08/17/17 / #20170232694

Lighting optics for luminaires

Disclosed herein are systems and methods for forming illumination affects through the use differing material disposed around various light sources. In some embodiments led light sources are used. ... Code 3 Inc

08/17/17 / #20170232016

Aza-heteroaryl compounds as pi3k-gamma inhibitors

And pharmaceutically acceptable salts thereof, wherein x, y, z, a, w, r4, r5, and r6 are defined herein, that inhibit the activity of phosphoinositide 3-kinases-gamma (pi3kγ) and are useful in the treatment of diseases related to the activity of pi3kγ including, for example, autoimmune diseases, cancer, cardiovascular diseases, and neurodegenerative diseases.. . ... Code 3 Inc

08/17/17 / #20170231986

Therapeutic combinations of a btk inhibitor, a pi3k inhibitor, a jak-2 inhibitor, and/or a bcl-2 inhibitor

Therapeutic combinations of a phosphoinositide 3-kinase (pi3k) inhibitor, including pi3k inhibitors selective for the γ- and δ-isoforms and selective for both γ- and δ-isoforms (pi3k-γ,δ, pi3k-γ, and pi3k-δ), a janus kinase-2 (jak-2) inhibitor, a bruton's tyrosine kinase (btk) inhibitor, and/or a b-cell lymphoma-2 (bcl-2) inhibitor are described. In some embodiments, the invention provides therapeutic combinations of a pi3k-δ inhibitor and a btk inhibitor, a jak-2 and a btk inhibitor, and a bcl-2 and btk inhibitor.. ... Code 3 Inc

08/10/17 / #20170227799

Active matrix substrate, liquid crystal panel, and method for manufacturing active matrix substrate

An active matrix substrate for a liquid crystal panel of an ffs mode includes a plurality of connecting units in a connecting region in order to electrically connect a common electrode, a first common main wiring 31, and a second common main wiring 32. The connecting unit includes a contact hole 41 that connects a connecting electrode 37 and the first common main wiring 31, the connecting electrode 37 formed integrally with the common electrode, and a contact hole 42 that connects the connecting electrode 37 and the second common main wiring 32. ... Code 3 Inc

08/10/17 / #20170227582

Non-contact ac voltage measurement device

A non-contact ac voltage measurement device 100 applied to a conductor 12 of an electric wire 16, the device 100 being characterized in that a first electrode 32 is provided outside the electric wire 16, whereby a coupling capacitance 34 is formed between the conductor 12 and the first electrode 32, a parallel circuit 38 having a capacitor 40 and an opening/closing means 50 connected in parallel to the capacitor 40 is provided, the parallel circuit is connected in series to the coupling capacitance, and a first current i1 which flows through the parallel circuit 38 when the opening/closing means 50 of the parallel circuit 38 is closed and a second current i2 which flows through the parallel circuit 38 when the opening/closing means 50 is open are measured for the purpose of measuring the ac voltage 8 applied to the conductor 12.. . ... Code 3 Inc

08/10/17 / #20170226109

Pyrazole derivatives as phosphoinositide 3-kinases inhibitors

Compounds of formula (i) defined herein are phosphoinositide 3-kinases (pi3k) inhibitors and are useful for the treatment of disorders associated with pi3k enzymes.. . ... Code 3 Inc

08/10/17 / #20170224819

Therapeutic combinations of a btk inhibitor, a pi3k inhibitor, a jak-2 inhibitor, and/or a cdk 4/6 inhibitor

Therapeutic combinations of a phosphoinositide 3-kinase (pi3k) inhibitor, including pi3k inhibitors selective for the γ- and δ-isoforms and selective for both γ- and δ-isoforms (pi3k-γ,δ, pi3k-γ, and pi3k-δ, a janus kinase-2 (jak-2) inhibitor, a cyclin-dependent kinase-4/6 (cdk4/6) inhibitor, and/or a bruton's tyrosine kinase (btk) inhibitor are described. In certain embodiments, the invention includes therapeutic combinations of a cyclin-dependent kinase-4/6 (cdk4/6) inhibitor and a btk inhibitor, a pi3k-δ inhibitor and a btk inhibitor, a jak-2 and a btk inhibitor, and a jak-2, pi3k-δ, and btk inhibitor.. ... Code 3 Inc

08/03/17 / #20170219899

Active matrix substrate, liquid crystal panel, and method for manufacturing active matrix substrate

An active matrix substrate for a liquid crystal panel of an ffs mode includes gate lines, data lines, pixel circuits each including a switching element and a pixel electrode, a protective insulating film formed in a layer over these elements, and a common electrode 30 formed in a layer over the protective insulating film. The common electrode 30 has slits 31 corresponding to the pixel electrode, for generating a lateral electric field to be applied to a liquid crystal layer. ... Code 3 Inc

07/20/17 / #20170207703

Current mode 3-state buck-boost pwm control architecture

A voltage regulator including a converter and a modulator. The converter includes a switching circuit coupled to an inductor for converting an input voltage to an output voltage. ... Code 3 Inc

07/20/17 / #20170203496

Reinforcement of structures using 3d-fabric wrap

A method and an article of manufacture are disclosed for reinforcing various structures, such as pipes, ducts, vessels, tanks, silos, chimneys, columns and the like, constructed from various materials including steel, concrete, masonry, wood, plastics, and the like. Some of the various structures may be used to transport water, gas, oil, and the like. ... Code 3 Inc

07/13/17 / #20170201073

Light-emitting element and manufacturing method thereof

A light-emitting element includes at least a gan substrate 11; a first light reflecting layer 41 formed on the gan substrate 11 and functioning as a selective growth mask layer 44; a first compound semiconductor layer 21, an active layer 23, and a second compound semiconductor layer 22 that are formed on the first light reflecting layer; and a second electrode 32 and a second light reflecting layer 42 that are formed on the second compound semiconductor layer 22. An off angle of the plane orientation of the surface of the gan substrate 11 is 0.4 degrees or less, the area of the first light reflecting layer 41 is 0.8s0 or less, where s0 represents the area of the gan substrate 11, and as a bottom layer 41a of the first light reflecting layer, a thermal expansion relaxation film 44 is formed on the gan substrate 11.. ... Code 3 Inc

07/13/17 / #20170200901

Light-emitting device, electronic apparatus, and inspection method

A light-emitting device 100 of the invention includes a light-emitting element 1a including an anode 3, a cathode 8, and a light-emitting layer 5 which is provided between the anode 3 and the cathode 8 and emits light in a near-infrared region by applying a current between the anode 3 and the cathode 8, wherein the device emits visible light with a luminance of 5 cd/m2 or more when a current is applied between the anode 3 and the cathode 8 at a current density of 300 a/cm2 or less.. . ... Code 3 Inc

07/06/17 / #20170194769

Spark plug for internal combustion engine

A spark plug 5 for an internal combustion engine includes a center electrode 1, an insulator 2, and a housing 3. The insulator 2 includes a distal end side exposed part and an insulator enlarged diameter part 21. ... Code 3 Inc

07/06/17 / #20170190689

Pyridine and pyridimine compounds as pi3k-gamma inhibitors

The present disclosure provides compounds of formula i, or pharmaceutically acceptable salts thereof, that modulate the activity of phosphoinositide 3-kinases-gamma (pi3kγ) and are useful in the treatment of diseases related to the activity of pi3kγ including, for example, autoimmune diseases, cancer, cardiovascular diseases, and neurodegenerative diseases.. . ... Code 3 Inc

07/06/17 / #20170189409

Medical use

The present invention provides a compound, which is an inhibitor of phosphoinositide 3-kinase delta or a pharmaceutically acceptable salt and/or solvate thereof, for use in the treatment of an immunobullous skin disease mediated by autoantibodies by oral administration.. . ... Code 3 Inc

06/22/17 / #20170180719

Projection display providing additional modulation and related methods

A projection display system includes a spatial modulator that is controlled to compensate for flare in a lens of the projector. The spatial modulator increases achievable intra-frame contrast and facilitates increased peak luminance without unacceptable black levels. ... Code 3 Inc

06/22/17 / #20170178402

Line guided three-dimensional model reshaping method

The invention provides a line guided 3d model reshaping method, including: 1. Extracting a contour of an object from an image, and selecting a contour or main skeleton to create a 2d line database; 2. ... Code 3 Inc

06/22/17 / #20170172662

Quantitative three-dimensional visualization of instruments in a field of view

A system is provided that includes a q3d endoscope disposed to image a field of view and a processor that produces a q3d model of a scene and identifies target instruments and structures. The processor is configured to display the scene from a virtual field of view of an instrument, to determine a no fly zone around targets, to determine a predicted path for said instruments or to provide 3d tracking of said instruments.. ... Code 3 Inc

06/15/17 / #20170170142

Nitride-enriched oxide-to-oxide 3d wafer bonding

A semiconductor structure comprising a first semiconductor structure; a second semiconductor structure; and a silicon-nitride layer configured to bond the first semiconductor structure and second semiconductor structure together. The first semiconductor structure comprises a first wafer; a first dielectric layer; a first interconnect structure; and a first oxide layer. ... Code 3 Inc

06/08/17 / #20170158699

Addition salts of (s)-2-(1-(6-amino-5-cyanopyrimidin-4-ylamino)ethyl)-4-oxo-3-phenyl-3,4-dihydropyrrolo[1,2-f][1,2,4]triazine-5-carbonitrile

The present invention is directed to novel pharmaceutically acceptable, addition salts of (s)-2-(1-(6-amino-5-cyanopyrimidin-4-ylamino)ethyl)-4-oxo-3-phenyl-3,4-dihydropyrrolo[1,2-f][1,2,4]triazine-5-carbonitrile with sulfonic acid derivatives, in particular with methanesulfonic acid, naphthalene-2-sulfonic acid and para-toluenesulfonic acid, and pharmaceutically acceptable solvates thereof, and their use as phosphoinositide 3-kinase (pi3k) inhibitors.. . ... Code 3 Inc

06/08/17 / #20170158696

N-(1-(substituted-phenyl)ethyl)-9h-purin-6-amines as pi3k inhibitors

The present invention provides n-(1-(substituted-phenyl)ethyl)-9h-purin-6-amines derivatives that modulate the activity of phosphoinositide 3-kinases (pi3ks) and are useful in the treatment of diseases related to the activity of pi3ks including, for example, inflammatory disorders, immune-based disorders, cancer, and other diseases.. . ... Code 3 Inc

06/08/17 / #20170158517

Silicon core wire for producing polycrystalline silicon rod, and device for producing polycrystalline silicon rod

A core wire holder 34 (holding member) has a taper of a positive taper angle on the lower end part thereof. On the other hand, in an adaptor 33 (supporting member) to be used for connection of a metal electrode 30 with the core wire holder 34 (holding member) for energization of a silicon core wire 100, the inner surface of a hole of the adaptor 33 into which the lower end part of the core wire holder 34 (holding member) is inserted, when the opening side of the hole is set upward and the insertion direction of the lower end part of the holding member is set downward, has a taper of a positive taper angle. ... Code 3 Inc

06/01/17 / #20170151264

Combination

The present invention provides a pharmaceutical composition which comprises (a) a compound which is an inhibitor of phosphoinositide 3-kinase delta or a pharmaceutically acceptable salt and/or solvate thereof, and (b) a corticosteroid.. . ... Code 3 Inc

05/18/17 / #20170142216

Proxy node for transferring packets between a server and a client using port sharding

The present disclosure relates to a proxy node 30, a method and a computer program in a proxy node in an ip network for transferring tcp packets between a server 40 and a client 20. The disclosure comprises modifying the port number of the server of at least one object so as to create the appearance that the at least one object, which resides on the same server, is residing on a different server, and causing the client 20 to open an additional tcp connection for the at least one object, whereby the speed of downloading web content can be accelerated.. ... Code 3 Inc

05/18/17 / #20170141337

Light-emitting element, light-emitting device, authentication device, and electronic apparatus

A light-emitting element 1 of the invention includes an anode 3, a cathode 8, a light-emitting layer 5 which is provided between the anode 3 and the cathode 8 and emits light in a wavelength range of 700 nm or more by applying a current between the anode 3 and the cathode 8, and an electron transport layer 6 which is provided between the light-emitting layer 5 and the cathode 8, and includes a first electron transport layer 6b located on the cathode 8 side and a second electron transport layer 6a located on the light-emitting layer 5 side, wherein the first electron transport layer 6b contains a first anthracene-based compound, which has an anthracene skeleton and a nitrogen-containing heterocyclic skeleton, and has an average thickness of less than 8 nm, and the second electron transport layer 6a contains a second anthracene-based compound, which has an anthracene skeleton but does not have a heterocyclic skeleton.. . ... Code 3 Inc

05/18/17 / #20170138614

Air-conditioning-apparatus indoor unit

Body air outlets 10d of an air-conditioning-apparatus indoor unit 100 each has a substantially trapezoidal shape in plan view and are each defined by a body-air-outlet outer side wall 10d2, a body-air-outlet inner side wall 10d4, and a pair of body-air-outlet end walls 10d1. The body-air-outlet outer side wall 10d2 is provided with a deflection guide 2 at each of long-side ends thereof. ... Code 3 Inc

05/18/17 / #20170138543

Solid state lamp using light emitting strips

In one embodiment, an led lamp has a generally bulb shape. The leds are low power types and are encapsulated in thin, narrow, flexible strips. ... Code 3 Inc

05/18/17 / #20170137920

Heat treatable aluminum alloys having magnesium and zinc and methods for producing the same

New magnesium-zinc aluminum alloy bodies and methods of producing the same are disclosed. The new magnesium-zinc aluminum alloy bodies generally include 3.0-6.0 wt. ... Code 3 Inc

05/18/17 / #20170136014

Therapeutic combinations of a btk inhibitor, a pi3k inhibitor and/or a jak-2 inhibitor

Therapeutic combinations of a janus kinase-2 (jak-2) inhibitor, a bruton's tyrosine kinase (btk) inhibitor, and/or a phosphoinositide 3-kinase (pi3k) inhibitor, including pi3k inhibitors selective for the γ- and δ-isoforms and selective for both γ- and δ-isoforms, are described. In some embodiments, the invention provides pharmaceutical compositions comprising combinations of (1) a pi3k-δ inhibitor and a btk inhibitor, (2) a jak-2 inhibitor and a btk inhibitor, or (3) a jak-2 inhibitor, pi3k-δ inhibitor, and btk inhibitor, and methods of using the pharmaceutical compositions for treating a disease, in particular a cancer.. ... Code 3 Inc

05/11/17 / #20170133252

Techniques for combining cmp process tracking data with 3d printed cmp consumables

Chemical mechanical polishing (cmp) apparatus and methods for manufacturing cmp apparatus are provided herein. Cmp apparatus may include polishing pads, polishing head retaining rings, and polishing head membranes, among others, and the cmp apparatus may be manufactured via additive manufacturing processes, such as three dimensional (3d) printing processes. ... Code 3 Inc

05/04/17 / #20170121783

Cobalt-lean alnico alloy

Provided is an alnico alloy that is lean (i.e., lower) in co content and yet at least retains substantially the same or better magnetic properties as the corresponding more costly, commercially available alnico grade alloy with higher co content, such as grades 8 and 9, which include 31.5 atomic % or more co, in order to save significant material costs.. . ... Code 3 Inc

04/27/17 / #20170112844

Benzimidazole derivatives as pi3 kinase inhibitors

This invention relates to the use of benzimidazole derivatives for the modulation, notably the inhibition of the activity or function of the phosphoinositide 3′ oh kinase family (hereinafter pi3 kinases), suitably, pi3kα, pi3kδ, pi3kβ, and/or pi3kγ. Suitably, the present invention relates to the use of benzimidazoles in the treatment of one or more disease states selected from: autoimmune disorders, inflammatory diseases, cardiovascular diseases, neurodegenerative diseases, allergy, asthma, pancreatitis, multiorgan failure, kidney diseases, platelet aggregation, cancer, sperm motility, transplantation rejection, graft rejection and lung injuries. ... Code 3 Inc

04/13/17 / #20170102545

Wearable 3d augmented reality display with variable focus and/or object recognition

A wearable 3d augmented reality display and method, which may include 3d integral imaging optics.. . ... Code 3 Inc

04/13/17 / #20170101393

Process for the preparation of 3-(3-chloro-1h-pyrazol-1-yl)pyridine

3-(3-chloro-1h-pyrazol-1-yl)pyridine is prepared by cyclizing 3-hydrazinopyridine-dihydrochloride with commercially available 3-ethoxyacrylonitrile to provide 3-(3-amino-1h-pyrazol-1-yl)pyridine, and by converting the amino group to a chloro group by a sandmeyer reaction.. . ... Code 3 Inc

04/06/17 / #20170098841

Porous current collector and fuel cell

Provided is a porous current collector which is used for a fuel electrode and has a high gas reforming function and high durability. A porous current collector 9 is provided adjacent to a fuel electrode 4 of a fuel cell 101 that includes a solid electrolyte layer 2, the fuel electrode 4 disposed on one side of the solid electrolyte layer, and an air electrode 3 disposed on the other side. ... Code 3 Inc

04/06/17 / #20170095592

Compositions for an injectable, in situ forming neuroscaffold and methods of using the same

Disclosed are injectable, biodegradable neuroscaffolds formed in situ by self-assembling biodegradable polymeric microparticles, nanoparticles, or any combination thereof, via copper-free click chemistry or michael-type addition coupling reactions. The injectable, biodegradable neuroscaffolds provide 3-d structural support, neuroprotection, and/or subsequent regeneration in a subject with a spinal cord injury or a focal neurological disorder.. ... Code 3 Inc

03/30/17 / #20170091983

Four-dimensional path-adaptive anchoring for immersive virtual visualization systems

Embodiments include systems and methods for synthesizing, recording, performing and playing back visual music for virtual immersive video playback environments. Virtual music (vm) compositions can include 3d vm instruments, which can be controlled in a highly dynamic and expressive manner using human interface controllers. ... Code 3 Inc

03/30/17 / #20170091980

Visual music synthesizer

Embodiments include systems and methods for synthesizing, recording, performing and playing back visual music for virtual immersive video playback environments. Virtual music (vm) compositions can include 3d vm instruments, which can be controlled in a highly dynamic and expressive manner using human interface controllers. ... Code 3 Inc

03/16/17 / #20170078652

A wearable 3d augmented reality display

A wearable 3d augmented reality display and method, which may include 3d integral imaging optics.. . ... Code 3 Inc

03/09/17 / #20170065083

Articulated chair having universal reclining armrest system

A universal reclining armrest system for use with an articulated examination chair. The system includes an armrest adapter having a universal aperture for receiving a post portion of an armrest assembly. ... Code 3 Inc

03/02/17 / #20170064582

Node, master device, and communication control system, method, and program

A node is included in a communication control system including a plurality of nodes 31, and a master device 30 for performing flow control of multihop communication in a network including the plurality of nodes 31. To the node 31 in use of second service, a time obtained by subtracting, from a frame period of the network, a total one frame transmission time of each node, used for first service is allocated as one frame transmission time used for second service having a priority set lower than that of the first service.. ... Code 3 Inc

02/23/17 / #20170052639

Touch panel and method for manufacturing the same

A touch panel 10 includes a first electrode-side terminal portion 42a that is electrically connected to an upper detection electrode 36a. The first electrode-side terminal portion 42a includes a first resin layer 44a which is provided on a first substrate 34a and in which a first terminal groove 54a is formed and a first conductive material 48a which fills the first terminal groove 54a. ... Code 3 Inc

02/23/17 / #20170050987

Pyrimidinones as pi3k inhibitors

The present invention provides pyrimidinones that modulate the activity of phosphoinositide 3-kinases (pi3ks) and are useful in the treatment of diseases related to the activity of pi3ks including, for example, inflammatory disorders, immune-based disorders, cancer, and other diseases.. . ... Code 3 Inc

02/16/17 / #20170048983

Chip resistor and electronic device

[object] to provide a chip resistor with which laser irradiation requires no extremely high positional accuracy, and a plating layer provided on a base and adjacent to a resistor element can be connected to an external conductive layer. [solution] a chip resistor includes a base 1, a first principal surface electrode 21, a second principal surface electrode spaced apart from the first principal surface electrode 21 in a first direction x1, a resistor element 4 in contact with the first principal surface electrode 21 and the second principal surface electrode 31, an overcoat 6 covering the resistor element 4, the first principal surface electrode 21 and the second principal surface electrode, a first auxiliary electrode 25 covering the first principal surface electrode 21 and the overcoat 6, and a first plating electrode 27 covering the first auxiliary electrode 25. ... Code 3 Inc

02/16/17 / #20170047213

Charged-particle detector and method of controlling the same

The present embodiment relates to a charged-particle detector, etc. Provided with a structure for effectively suppressing ion feedbacks under a low-vacuum environment. ... Code 3 Inc

02/16/17 / #20170044544

Oligonucleotide specific uptake of nanoconjugates

Disclosed are nanoparticles functionalized with an oligonucleotide and a domain, wherein the domain increases cellular uptake of the nanoparticles. The domain is a sequence of nucleobases or phosphate groups, such as a poly thymidine (polyt) sequence or a phosphate polymer (c3 residue) and may be located 5′ to the oligonucleotide 3′ to the oligonucleotide, within, or colinear with the oligonucleotide. ... Code 3 Inc

02/16/17 / #20170044134

Process for the preparation of 3-(3-chloro-1h-pyrazol-1-yl)pyridine

3-(3-chloro-1h-pyrazol-1-yl)pyridine is prepared by cyclizing 3-hydrazinopyridine-dihydrochloride with a dialkyl maleate to provide an alkyl 5-oxo-2-(pyridin-3-yl)pyrazolidine-3-carboxylate, by chlorinating to provide an alkyl 3-chloro-1-(pyridin-3-yl)-4,5-dihydro-1h-pyrazole-5-carboxylate, by oxidizing to provide an alkyl 3-chloro-1-(pyridin-3-yl)-1h-pyrazole-5-carboxylate, by converting the ester to the carboxylic acid by hydrolysis to provide 3-chloro-1-(pyridin-3-yl)-1h-pyrazole-5-carboxylic acid hydrochloride, and by removing the carboxylic acid by a decarboxylation reaction.. . ... Code 3 Inc

02/16/17 / #20170043341

Microfluidic device

A microfluidic device 10 is provided that includes a porous substrate 12 and a plurality of reaction channels 14 disposed on a first side 36 of the porous substrate 12. The reaction channels 14 are defined by a barrier material 16 disposed on the substrate 12 in a user-defined pattern 13. ... Code 3 Inc

02/02/17 / #20170033533

Light emitting element

A light emitting element includes at least a first light reflecting layer 41 formed on a surface of a substrate 11, a laminated structural body 20 made of a first compound semiconductor layer 21, an active layer 23 and a second compound semiconductor layer 22 formed on the first light reflecting layer 41, and a second electrode 32 and a second light reflecting layer 42 formed on the second compound semiconductor layer 22, the laminated structural body 20 is configured from a plurality of laminated structural body units 20a, a light emitting element unit 10a is configured from each of the laminated structural body units 20a, and a resonator length in the light emitting element unit 10a is different in every light emitting element unit.. . ... Code 3 Inc

02/02/17 / #20170028571

Knife and blade finishing method

A first cutting blade 5 is formed on a blade edge portion 3a on one side in a blade thickness direction of a blade 3, a second cutting blade 7 is formed on a blade edge portion on other side in the blade thickness direction of the blade 3, a handle 9 is provided on the blade 3, a hard coating 11 if formed by pvd or cvd on the blade edge portion 3b on the other side in the blade thickness direction of the blade 3, a rough surface 13 is formed by grinding processing or shot blast processing on a base of the hard coating 11 on the blade edge portion 3b on the other side in the blade thickness direction of the blade 3, and a maximum height rz of surface roughness of the rough surface 13 is set to 10 to 30 μm.. . ... Code 3 Inc

01/19/17 / #20170014926

Control device for wire electric discharge machine and control method for wire electric discharge machine

A control device for a wire discharge machine including an interpolar average machining voltage detection unit 5 that detects an interpolar average machining voltage between an electrode 3 and a workpiece 4 to be machined, an interpolar average machining voltage correction unit 12 that corrects the interpolar average machining voltage detected by the interpolar average machining voltage detection unit, a set voltage storage unit 6 that stores, in advance, a set voltage serving as a target value of the interpolar average machining voltage, a voltage calculation unit 7 that calculates a difference between the set voltage and an output of the interpolar average machining voltage correction unit 12, a machining speed control unit 8 that calculates a machining speed of the electrode based on the difference calculated by the voltage calculation unit 7, a drive control device 9 that controls a machining speed of the electrode in accordance with the calculated machining speed, a set speed storage unit 10 that sets, in advance, a set speed serving as a target value of the machining speed, and a voltage correction value calculation unit 12 that calculates an interpolar average machining voltage correction value based on a difference between the machining speed and the set speed, wherein the interpolar average machining voltage correction unit 12 corrects the interpolar average machining voltage in accordance with the interpolar average machining voltage correction value.. . ... Code 3 Inc

01/12/17 / #20170012068

Solid-state image pickup device

A solid-state image pickup device 1 according to the present invention includes a semiconductor substrate 2 on which a pixel 20 composed of a photodiode 3 and a transistor is formed. The transistor comprising the pixel 20 is formed on the surface of the semiconductor substrate, a pn junction portion formed between high concentration regions of the photodiode 3 is provided within the semiconductor substrate 2 and a part of the pn junction portion of the photodiode 3 is extended to a lower portion of the transistor formed on the surface of the semiconductor substrate 2. ... Code 3 Inc

01/12/17 / #20170010296

Plant water dynamics sensor

The plant water dynamics sensor comprises: a heater-equipped temperature probe 10 including a temperature sensor 11 and a heater 12; a temperature probe 20 including a temperature sensor 21; an electrical resistance probe 30 including an electrical resistance measurement electrode 33; and a support 80 that supports the probes 10, 20, and 30 while the probes are aligned parallel to each other. The position of a xylem xy can be detected based on an electrical resistance measured at the electrical resistance probe 30, so that each of the temperature sensors 11 and 21 can be arranged correctly in a position at a phloem ph or at the xylem xy. ... Code 3 Inc

01/05/17 / #20170003500

Drive apparatus

A mirror device 300 disclosed herein includes: a base 302; a mirror 305; an actuator 306; an extension 304 provided on the other side of the mirror 305 with respect to an x-axis opposite from the actuator 306; a fixed comb electrode 308; and a movable comb electrode 307 provided on the other side of the mirror 305 with respect to the x-axis opposite from the actuator 306. The movable comb electrode 307 includes: a beam portion 371 coupled to the mirror 305 via a hinge 373; and electrode fingers 372 provided for the beam portion 371. ... Code 3 Inc








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