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Colorado State University Research Foundation patents


Recent patent applications related to Colorado State University Research Foundation. Colorado State University Research Foundation is listed as an Agent/Assignee. Note: Colorado State University Research Foundation may have other listings under different names/spellings. We're not affiliated with Colorado State University Research Foundation, we're just tracking patents.

ARCHIVE: New 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 | Company Directory "C" | Colorado State University Research Foundation-related inventors


Use of equol for treating androgen mediated diseases

Equol (7-hydroxy-3(4′hydroxyphenyl)-chroman), or metabolite of the phytoestrogen daidzein, specifically binds and blocks the hormonal action of 5α-dihydrotestosterone (dht) in vitro and in vivo. Equol can bind circulating free dht and sequester it from the androgen receptor, thus altering growth and physiological hormone responses that are regulated by androgens. ... Colorado State University Research Foundation

Fire alarm system

A method may include gathering data from a first set of sensors disposed throughout a first facility at a first fire alarm control panel. The method may also include exchanging one or more messages between the first fire alarm control panel and a control center computer. ... Colorado State University Research Foundation

Engineered model of fibrotic diseases

The present disclosure provides co-cultures of a population of hepatocytes, at least one non-parenchymal cell population, and a population of hepatic stellate cells in vitro, methods of preparing the co-cultures, and methods of using the co-cultures for high throughput screening and evaluation of drug candidates. The hepatocytes co-culture system provides an in vitro model in which both cell viability and phenotype are maintained for extended periods relative to conventional monoculture.. ... Colorado State University Research Foundation

Synergistic bacterial consortia for mobilizing soil phosphorus

The present disclosure relates to consortia of bacteria strains and composition comprising one or more bacterial strains disclosed herein. These consortia of isolated bacteria cultures and compositions comprising said cultures, having greater activity than would be observed for the individual bacteria cultures and compositions. ... Colorado State University Research Foundation

Ring-opening polymerization methods and recyclable biorenewable polyesters

The invention provides polymers of formulas i-iii, such as polyesters and unsaturated polyesters, and crosslinked and copolymerized polymers thereof. The invention also provides methods to catalytically ring-open five-membered rings such lactones, lactams, and thiolactones, as via ring-opening polymerization. ... Colorado State University Research Foundation

Synthetic repression of gene expression in plants

The present disclosure provides synthetic repressor constructs and the proteins encoded therein, as well as synthetic repressible promoter constructs for use in combination with the synthetic repressor constructs/synthetic repressors disclosed herein. Various combinations of synthetic repressor constructs and synthetic repressible promoter constructs are also provided in synthetic genetic circuits for modifying expression of a protein of interest in a plant cell.. ... Colorado State University Research Foundation

Optimized cancer stem cell vaccines

The present invention provides cancer stem cell vaccines useful for treating or preventing a variety of tumors, as well as related methods of producing cancer stem cells and antigens thereof and producing vaccine adjuvants with enhanced activity for use with the stem cell vaccines.. . ... Colorado State University Research Foundation

Phototunable thermoplastic elastomer hydrogel networks

Provided herein is a thermoplastic elastomer hydrogel and methods of making such. The hydrogel comprises a glass formed from poly(styrene)-b-poly(ethylene oxide) in which the coronal chain end has been functionalized with photodimerizable groups (ab-photo) and a liquid medium at a concentration between about 32:1 and about 2:1 liquid medium/ab-photo by weight. ... Colorado State University Research Foundation

Indole-based therapeutics

Provided herein are indole-2-carboxamide compounds useful for the treatment of non-tuberculosis bacterial infections. Exemplary compounds provided herein are useful for the treatment of non-tuberculosis mycobacterial infections. ... Colorado State University Research Foundation

Use of peptide-based inhibitors of the stat3-il10 pathway for treating bacterial infection and granulomatous disease

The invention provides a method of treating pathogenic bacterial infection (e.g., tuberculosis infection) in an animal comprising administering a peptide-based inhibitor of the stat3-il10 pathway or a nucleic acid encoding the peptide-based inhibitor to the animal. The invention also provides methods of treating chronic granulomatous disease and wegener's granulomatosis in an animal comprising administering a peptide-based inhibitor of the stat3-il10 pathway or a nucleic acid encoding the peptide-based inhibitor to the animal.. ... Colorado State University Research Foundation

Portable air sampling device

A sampling device is constructed having an airflow path from a size-selective inlet to a device outlet, without using any tubing. The size-selective inlet includes at least one of an impactor, a filter, a cyclone, and an inhalable inlet. ... Colorado State University Research Foundation

Cryogenic core collection

A system and method for collecting a core sample. The system includes an outer cylindrical tube, a drive head, a drive shoe, a cooling chamber housed inside the outer cylindrical tube, insulation, a core sample liner, an inlet tube, and outlet tube. ... Colorado State University Research Foundation

Engineered programmable molecular scaffolds from porous protein crystals

The present disclosure provides compositions and methods for preparing engineered porous protein crystals comprising at least one guest molecule.. . ... Colorado State University Research Foundation

Methods and compositions for enhancing an immune response, blocking monocyte migration, amplifying vaccine immunity and inhibiting tumor growth and metastasis

Provided are methods of enhancing an immune response and methods for reducing the recruitment of monocytes to a lymph node by administering to an individual an angiotensin ii receptor blocker or a compound of formula (i) in conjunction with an antigen. The invention also provides relate methods for amplifying vaccine immunity by administering to an individual an angiotensin ii receptor blocker or a compound of formula (i) in conjunction with an vaccine. ... Colorado State University Research Foundation

11/30/17 / #20170346134

Multi-functional electrolyte for thermal management of lithium-ion batteries

The high thermal conduction resistances of a lithium-ion battery (lib) severely limit the effectiveness of a conventional external thermal management system (tms). A method for a new thermal management system for lithium-ion batteries that utilizes a multi-functional electrolyte (mfe) to remove heat locally inside the cell by evaporating a volatile component of the mfe is disclosed. ... Colorado State University Research Foundation

11/30/17 / #20170339989

Meat and methods of preparing same having reduced sodium content

Methods of producing meat compositions with reduced salt content are provided. The process includes providing meat pieces which are bound by cold-binding agents, and in which no salt or reduced salt amounts are added to the meat pieces. ... Colorado State University Research Foundation

11/23/17 / #20170336320

Laser sensor for trace gas detection

Systems and methods are disclosed to determine the concentration of a species within a sample. An example method may include collecting optical loss data over a range of frequencies from the sample using a spectroscopy system; placing the optical loss data into a plurality of bins, each bin having a defined frequency width; determining an average optical loss data value for the optical loss values within each bin that have an optical loss value less than a threshold value; removing the optical loss data within each bin having a value outside a tolerance range bounding the average optical loss data value for the respective bin; fitting a spectral curve to the remaining optical loss data; and determining the concentration of the species within the sample based on the spectral curve.. ... Colorado State University Research Foundation

11/16/17 / #20170327905

High throughput method to genotype plants

Methods are provided for high throughput genotyping of plants, utilizing at least three primers, one primer recognizing a polymorphic sequence of a first species of a plant genus, a second primer recognizing a second polymorphic sequence of a second species, and a third primer that recognizes sequences of both the first and second species and producing a measurable signal when amplifying a plant dna-containing sample. Additional primers recognizing additional species may also be employed. ... Colorado State University Research Foundation

10/05/17 / #20170281754

Compositions and methods for enhanced innate immunity

The disclosed compositions and methods relate to an immunogenic composition that, in certain aspects, comprise cationic liposomes; a mixture of toll like receptor 3 (tlr3) and toll like receptor 9 (tlr9) ligands; and a cellular adhesion agent, and methods of using such compositions. In certain aspects, disclosed compositions are administered to a mammal to induce a non-specific innate immune response at mucosal surfaces. ... Colorado State University Research Foundation

10/05/17 / #20170280859

Personal sampling belt

Implementations described and claimed herein provide an industrial hygiene sampling system including a personal sampling belt and one or more sampling pouches. In one implementation, a belt body has an inner surface and an outer surface extending between a body proximal edge and a body distal edge. ... Colorado State University Research Foundation

08/31/17 / #20170249404

Mitigating latency errors in distributed systems

An example system includes a simulation system that emulates a first portion of an electrical system and controls, based on the first portion, electrical inputs to a device under test. The system also includes an observation device, operatively coupled to the simulation system, that receives a delayed version of a remote emulation value, which represents a second portion of the electrical system. ... Colorado State University Research Foundation

08/24/17 / #20170241353

Gaseous fuel consuming engine controlling systems

According to some embodiments, the present disclosure may relate to a system including a gaseous fuel consuming engine operating at an air to fuel ratio (afr) and including a throttle valve controlling a speed of engine, and an engine controller coupled to the engine. The engine controller may be configured to obtain the speed of the engine and obtain the afr of the engine. ... Colorado State University Research Foundation

08/17/17 / #20170232252

Tongue stimulation for communication of information to a user

Example devices and methods of tongue stimulation for communication of information to a user are disclosed herein. In an example, a tongue stimulation device may include a body configured to be placed entirely within a mouth of the user and atop the tongue of the user. ... Colorado State University Research Foundation

08/10/17 / #20170226583

Identification of cattle at risk of high altitude pulmonary hypertension

Provided herein are methods and compositions for determining the susceptibility of cattle to high altitude pulmonary hypertension. Also provide are kits and reagents for performing such methods.. ... Colorado State University Research Foundation

07/27/17 / #20170212044

Hydrocarbon sensing methods and apparatus

A chip-scale, reusable sensor can detect aromatic hydrocarbons, such as benzene, toluene, ethylbenzene, and xylenes (btex), rapidly in water without sample preparation. The device is capable of real-time, continuous monitoring for btex solutes, which diffuse into a film, such as a polymer, on the sensors surface. ... Colorado State University Research Foundation

07/20/17 / #20170204163

Compositions comprising resurfaced cell-penetrating nanobodies and methods of use thereof

The disclosure encompasses resurfaced cell-penetrating nanobodies and their methods of use. The resurfacing of nanobodies with positively-charged amino acids facilitates their penetration into a cell and allows targeting of a specific intracellular protein.. ... Colorado State University Research Foundation

07/06/17 / #20170189583

Polymeric materials including a glycosaminoglycan networked with a polyolefin-containing polymer

The present invention relates to polymeric materials including a glycosaminoglycan networked with a polyolefin-containing polymer. The present invention also relates to hydrogels containing the polymeric materials. ... Colorado State University Research Foundation

06/29/17 / #20170184483

Method and device for incoherent imaging with coherent diffractive reconstruction

Systems and methods are disclosed to determine the axial and/or lateral location of a particle using light modulated with temporal and/or spatial modulation pattern. The system, for example, may include a modulator configured to temporally modulate an intensity pattern of a line of light uniquely at each point along a lateral length of the line of light and produce an undiffracted modulated line of light, a first first-order diffracted line of light, and a second first-order diffracted line of light; and one or more optical elements configured to direct the undiffracted line of light and one of the first first-order diffracted line of light and the second first-order diffracted line of light toward at least one particle disposed at or near a sample region. ... Colorado State University Research Foundation

06/22/17 / #20170176311

Devices and methods for sorting droplets by surface tension

A tunable superomniphobic surface with flower-like tio2 nanostructures was fabricated into a device with precisely tailored surface energy domains that can sort droplets by surface tension. This apparatus and method for droplet sorting will enable inexpensive and energy-efficient analytical devices for personalized point-of-care diagnostic platforms, lab-on-a-chip systems, fuel sensor applications, biochemical assays and biosensors.. ... Colorado State University Research Foundation

06/08/17 / #20170158824

Reversible metallopolymer network

The invention provides a metallopolymer coordination network comprising one or more coinage or similar metals and a glyme or glyme-equivalent. The composition has an amorphous polymer network that is significantly stronger than previously reported supramolecular hydrogels synthesized without glyme. ... Colorado State University Research Foundation

04/13/17 / #20170101516

Material comprising outer layer having entanglement of hydrophobic polymer host blended with anhydride functionalized hydrophobic polymer co-host and hydrophilic guest

The present disclosure provides, inter alia, a method of producing an outer layer material for forming into a structure and that comprises an entanglement having a hydrophobic polymer host and a hydrophilic guest, including in one embodiment the steps of: intermingling cloaked hydrophilic guest complexes with the hydrophobic host; crosslinking molecules of the guest with the guest; and performing a hydrolysis reaction.. . ... Colorado State University Research Foundation

03/09/17 / #20170069197

Fire alarm system

A fire alarm control and monitoring system is disclosed. In some embodiments, the fire alarm and control system may include a plurality of fire alarm control panels connected together through a communication network. ... Colorado State University Research Foundation

03/02/17 / #20170059585

In vitro detection of prions in blood

A method of screening a blood sample for the presence of prions. The method includes the steps of collecting the blood sample in heparin, contacting the sample with a solution comprising recombinant prion protein (rprp) and thioflavin t (tht), and measuring the resulting tht fluorescence in the sample. ... Colorado State University Research Foundation

02/16/17 / #20170046985

Systems and methods for palpation training

Implementations described and claimed herein provide systems and methods for palpation training. In one implementation, a system for medical procedure simulation includes an examination model, a sensor network, and a computing device. ... Colorado State University Research Foundation

02/16/17 / #20170045272

Ultra efficient turbo-compression cooling

A turbo-compression cooling system includes a power cycle and a cooling cycle coupled one to the other. The power cycle implements a waste heat waste heat exchanger configured to evaporate a first working fluid and a turbine configured to receive the evaporated working fluid. ... Colorado State University Research Foundation

02/16/17 / #20170044124

Biorefining compounds and organocatalytic upgrading methods

The invention provides new methods for the direct umpolung self-condensation of 5-hydroxymethylfurfural (hmf) by organocatalysis, thereby upgrading the readily available substrate into 5,5′-di(hydroxymethyl) furoin (dhmf). While many efficient catalyst systems have been developed for conversion of plant biomass resources into hmf, the invention now provides methods to convert such nonfood biomass directly into dhmf by a simple process as described herein. ... Colorado State University Research Foundation

02/02/17 / #20170028390

Metal-organic framework functionalized polymeric compositions

A polymeric composition includes an organic polymeric substrate and metal-organic frameworks on the surface of the polymeric substrate. The metal-organic frameworks cover at least 90% of the surface area of the polymeric substrate.. ... Colorado State University Research Foundation

01/12/17 / #20170009270

Enzymatic biosensors with enhanced activity retention for detection of organic compounds

Enzymatic biosensors and methods of producing distal tips for biosensor transducers for use in detecting one or more analytes selected from organic compounds susceptible to dehalogenation, organic compounds susceptible to oxygenation and organophosphate compounds susceptible to hydrolysis are disclosed herein, as well as biosensor arrays, methods of detecting and quantifying analytes within a mixture, and devices and methods for delivering reagents to enzymes disposed within the distal tip of a biosensor.. . ... Colorado State University Research Foundation








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