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Complete Genomics Inc patents


Recent patent applications related to Complete Genomics Inc. Complete Genomics Inc is listed as an Agent/Assignee. Note: Complete Genomics Inc may have other listings under different names/spellings. We're not affiliated with Complete Genomics Inc, we're just tracking patents.

ARCHIVE: New 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 | Company Directory "C" | Complete Genomics Inc-related inventors


Biosensors for biological or chemical analysis and methods of manufacturing the same

Embodiments of the invention provide an improved biosensor for biological or chemical analysis. According to embodiments of the invention, backside illumination (bsi) complementary metal-oxide-semiconductor (cmos) image sensors can be used to effectively analyze and measure fluorescence or chemiluminescence of a sample. ... Complete Genomics Inc

Self-assembled single molecule arrays and uses thereof

The present invention provides methods of making and using self-assembled arrays of single polynucleotide molecules for carrying out a variety of large-scale genetic measurements, such as gene expression analysis, gene copy number assessment, and the like. Random arrays used in the invention are “self-assembled” in the sense that they are formed by deposition of polynucleotide molecules onto a surface where they become fixed at random locations. ... Complete Genomics Inc

Efficient arrays of amplified polynucleotides

The present invention is related generally to analysis of polynucleotides, particularly polynucleotides derived from genomic dna. The invention provides methods, compositions and systems for such analysis. ... Complete Genomics Inc

Methods and compositions for efficient base calling in sequencing reactions

The present invention is directed to methods and compositions for acquiring nucleotide sequence information of target sequences. In particular, the present invention provides methods and compositions for improving the efficiency of sequencing reactions by using fewer labels to distinguish between nucleotides and by detecting nucleotides at multiple detection positions in a target sequence.. ... Complete Genomics Inc

Imaging systems with movable scan mirrors

An imaging system is provided wherein a positioning stage is translated with respect to an objective lens component and a scan mirror is repositioned while a two-dimensional image is made of a biochemical site on a substrate. In an example embodiment, an imaging system comprises a camera, an objective lens component, a positioning stage, and a scan mirror controllable by a servo system that synchronizes movement of the positioning stage and the tilting of the scan mirror so that the substrate image is maintained stable during imaging of the continuously moving positioning stage.. ... Complete Genomics Inc

Method of aligning high-density biochemical array chips with asynchronous tracks by moirÉ averaging

An array chip useful for biochemical assays is provided wherein the chip includes a field region arranged with attachment sites according to a first pitch and at least one track region having a one-dimensional spot pattern arranged according to a second pitch that is less dense and is a non-integer multiple of the first pitch so that one-dimensional moiré averaging may be applied in the track region, thereby to attain alignment of the chip to the optical instrumentation with a higher density of attachment sites.. . ... Complete Genomics Inc

Affinity tag labeled nucleosides and uses

Nucleoside analogues and methods of using such nucleoside analogues for sequencing of nucleic acids are provided.. . ... Complete Genomics Inc

High throughput genome sequencing on dna arrays

The present invention is directed to methods and compositions for acquiring nucleotide sequence information of target sequences using adaptors interspersed in target polynucleotides. The sequence information can be new, e.g. ... Complete Genomics Inc

Dna sequencing from high density dna arrays using asynchronous reactions

The invention relates to an automated method for high-throughput dna sequencing from high density dna arrays by (a) initiating a first sequencing reaction on a first high density dna array; and imaging said first high density dna array using a detector, and (b) initiating a first sequencing reaction on a second high density dna array; and imaging said second high density dna array using the detector, wherein the first sequencing reaction in (a) is initiated before the first sequencing reaction in (b) is initiated such that the sequencing reactions in (a) and (b) are staggered. By using asynchronous sequencing reactions and imaging two separate arrays using one detector, imaging can be carried out on one array while sequencing reactions are carried out on one the other, substrate, the other substrate is imaged, reducing the idle time of the imaging system.. ... Complete Genomics Inc

High density dna array

A high density dna array comprising a patterned surface, said surface comprising a pattern of small dna binding regions separated by a non-dna binding surface, wherein the dna binding regions comprise dna capture chemistry and the non-dna binding surface does not have the dna capture chemistry wherein more than 50% of the dna binding regions in the array have single informative dna species.. . ... Complete Genomics Inc

Methods of preparing a library of nucleic acid fragments tagged with oligonucleotide bar code sequences

The present invention is directed to methods and compositions for long fragment read sequencing. The present invention encompasses methods and compositions for preparing long fragments of genomic dna, for processing genomic dna for long fragment read sequencing methods, as well as software and algorithms for processing and analyzing sequence data.. ... Complete Genomics Inc

Integrated system for nucleic acid sequence and analysis

An integrated end-to-end system for large-scale, high-quality nucleic acid sequencing having a nucleic acid extraction module, a library preparation module, a nucleic acid sequencing module, and a data analysis module reversibly integrated with one another and having components that are physically loosely-coupled within such system and reversibly integrated for sequence interrogation and analysis. This system is fully automated from sample to data output. ... Complete Genomics Inc

Multiple tagging of individual long dna fragments

This disclosure provides methods and compositions for tagging long fragments of a target nucleic acid for sequencing and analyzing the resulting sequence information in order to reduce errors and perform haplotype phasing, for example.. . ... Complete Genomics Inc

Techniques for scanned illumination

Imaging systems are provided for high speed, high resolution imaging of biochemical materials. In an example embodiment, an imaging system comprises an objective lens component, a line generator, a digital camera, a positioning stage, and a scan mirror. ... Complete Genomics Inc








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