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Cordis Corporation patents


Recent patent applications related to Cordis Corporation. Cordis Corporation is listed as an Agent/Assignee. Note: Cordis Corporation may have other listings under different names/spellings. We're not affiliated with Cordis Corporation, we're just tracking patents.

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 new patent  Multiple fluid model tool for interdisciplinary fluid modeling

A multiple fluid model tool for interdisciplinary fluid modeling is presented. For example, a system includes a modeling component, a machine learning component, and a three-dimensional design component. ... Cordis Corporation

 new patent  Method for integration of semantic data processing

The invention relates to a method for integration of semantic data processing in a device, in particular in a field device of automation technology. In this case, a generic description language scheme is used to define a semantic repository as a starting basis. ... Cordis Corporation

Lithium ion secondary battery and method of producing the lithium ion secondary battery

A lithium ion secondary battery includes a housing. An electrode group and an electrolytic solution are in the housing. ... Cordis Corporation

Double-acylated glp-1 derivatives

The invention relates to a derivative of a glp-1 analogue, which analogue comprises a first k residue at a position corresponding to position 27 of glp-1(7-37) (seq id no: 1); a second k residue at a position corresponding to position t of glp-1(7-37), where t is an integer in the range of 7-37 except 18 and 27; and a maximum of ten amino acid changes as compared to glp-1(7-37); wherein the first k residue is designated k27, and the second k residue is designated kt; which derivative comprises two albumin binding moieties attached to k27 and kt, respectively, via a linker, wherein the albumin binding moiety comprises a protracting moiety selected from hooc—(ch2)2—co— and hooc—c6h4—o—(ch2)y—co—; in which x is an integer in the range of 6-16, and y is an integer in the range of 3-17; wherein the linker comprises an element of the formula —nh—(ch2)2—(o—(ch2)2)k—o—(ch2)n—co—, wherein k is an integer in the range of 1-5, and n is an integer in the range of 1-5; or a pharmaceutically acceptable salt, amide, or ester thereof. The invention also relates to the pharmaceutical use thereof, for example in the treatment and/or prevention of all forms of diabetes and related diseases, as well as to corresponding novel glp-1 analogues. ... Cordis Corporation

Method of manufacturing display panel

The present disclosure discloses a method of manufacturing a display panel. The method includes: providing a first substrate, and forming a release layer on the first substrate; forming a thin film transistor driving layer on the first substrate; forming a display element on the first substrate, wherein a part of the display element forms above the release layer and another part of the display element forms above the thin film transistor driving layer; separating the release layer and the first substrate with a laser; removing the release layer and the display element above the release layer, and forming a hollow portion on the first substrate; packaging the display element to form a display panel, wherein the display panel at least includes a first packaging portion; and providing a through hole passing through the display panel at a region on the display panel corresponding to the hollow portion.. ... Cordis Corporation

Method for hydraulic fraturing (variants)

A method of stimulating the inflow of oil and/or gas from the wellbore, in particular, a hydraulic fracturing method, is disclosed. The method of hydraulic fracturing comprises the stages: injecting a slug of a proppant-free fluid through the well into a formation for hydraulic fracture creation and propagation; injecting a slug of proppant-laden slurry into the formation to create a proppant pack in the hydraulic fracture; injecting a slug of slurry that contains a fluid and the polyelectrolyte complex-based proppant aggregates to create permeable channels in the near-wellbore area of the hydraulic fracture; injecting a slug of a displacement fluid into the well. ... Cordis Corporation

Liraglutide in cardiovascular conditions

The present invention relates to the glp-1 receptor agonist liraglutide for use in medicine.. . ... Cordis Corporation

Tablet formulation comprising semaglutide and a delivery agent

The present invention relates to solid compositions comprising a glp-1 peptide and a delivery agent, such as snac, as well as uses thereof.. . ... Cordis Corporation

Battery pack protection element attachment tab, battery pack parallel fixing component, and battery pack

A protection element attachment tab made of a single flat metal plate and mounted on positive and negative electrode terminals of a cylindrical cell to connect between the positive electrode terminal formed on one end surface of the cell and the negative electrode terminal formed on another end surface of the cell with a protection element that prevents overdischarge between the electrode terminals. The protection element attachment tab includes a planar region facing the end surface when mounted on the electrode terminal; a first protrusion protruding from the planar region in a direction along the planar region, a leading end of the first protrusion protruding outward from the end surface of the cell when the planar region is mounted on the electrode terminal; and a second protrusion shorter than the first protrusion, protruding from the planar region in a direction different from the first protrusion along the planar region.. ... Cordis Corporation

A torsion spring driven injection device

The invention relates to a torsion spring driven injection device for apportioning individually set doses of a liquid drug. The injection device has a needle cannula (35) for multiple uses and a cleaning chamber (56) for cleaning the tip of the needle cannula between subsequent injections. ... Cordis Corporation

Growth hormones with prolonged in-vivo efficacy

The present invention relates to polypeptide compound optimized for subcutaneous administration, exemplified by growth hormone conjugates having a linker providing non-covalent binding to albumin.. . ... Cordis Corporation

Antibodies capable of specifically binding two epitopes on tissue factor pathway inhibitor

The application discloses a combination of two monospecific tfpi antibodies, wherein one antibody is capable of specifically binding tfpi (1-181) and the other antibody is capable of specifically binding tfpi (182-276), as well as bispecific anti-tfpi antibodies derived from two such monospecific antibodies. Both the combination of the two monospecific antibodies and the bispecific antibody strongly enhance thrombin generation by neutralising full length tfpiα, even where the concentration of tfpi is abnormally elevated.. ... Cordis Corporation

Anti-kir antibodies, formulations, and uses thereof

A novel igg4 isotype anti-kir antibody, novel formulations of this and other igg4 anti-kir antibodies, and methods of using such formulations are provided. Also described are compositions, formulations, dosages, and administration regimens suitable for nk cell activation and therapeutic applications of anti-kir antibodies, as well as kits comprising one or more anti-kir antibodies with instructions for use in treating cancer.. ... Cordis Corporation

Device and method for removal of pinbones from a fish fillet

The invention relates to an apparatus, designed and configured for the removal of pin bones from a fish fillet that has been completely separated from the skeleton, comprising a tool having a clamping mechanism for clamping and releasing individual pin bones, a drive for the rotary driving of at least parts of the clamping mechanism and means for transmitting the rotational movement from the drive to the clamping mechanism, which is characterised in that the clamping mechanism comprises a base body that can be driven such that it rotates about a rotational axis, with which at least two clamping jaws are associated, which clamping jaws define a resulting central axis m and are for clamping and releasing the pin bones, wherein the clamping jaws are designed and configured such that they can move towards and away from one another, and the drive is designed and configured for exerting an oscillating rotational movement of the base body about the rotational axis and thereby of the clamping jaws about the central axis m. The invention further relates to a corresponding method.. ... Cordis Corporation

07/19/18 / #20180204519

Display panel device

A display device includes a pixel array and a plurality of data lines for providing a data voltage signal for a sub-pixel unit in the pixel array, wherein each data line corresponds to a predefined series of sub-pixel units of each row of the pixel array and provides the data voltage signal to the predefined series of sub-pixel units, wherein the predefined series of sub-pixel units comprises a plurality of sub-pixel units.. . ... Cordis Corporation

07/12/18 / #20180197932

Array substrate and display panel

An array substrate includes: a substrate; a first metal layer, disposed on the substrate, the first metal layer forming a gate electrode, a scan line and a first electrode, the scan line extending along a first direction in a plane of a surface of the substrate; a first insulation layer, disposed on the first metal layer; a second metal layer, disposed on the first insulation layer, the second metal layer forming a second electrode, projections of the first electrode and the second electrode on the substrate at least partly overlapping one another; a second insulation layer, disposed on the second metal layer; and a third metal layer, disposed on a side of the second insulation layer away from the second metal layer, the third metal layer forming an initialization signal line.. . ... Cordis Corporation

07/12/18 / #20180193569

Pressure based event detection

The present invention provides a drug delivery device (1) comprising a drug delivery unit (10) comprising a dose expelling mechanism operable to expel a dose of drug from a drug reservoir (11), a cap (20) configured for dismountable mounting over a portion of the drug delivery unit (10), the cap (20) comprising a cavity (25, 26) for reception of the portion of the drug delivery unit (10), a seal (40) adapted to provide a sealing in an interface between the cap (20) and the drug delivery unit (10), a sensor system (30) configured to monitor internal pressure in the cavity (25, 26) and to register an event in response to sensing a change in the internal pressure which numerically exceeds a specified threshold level over a period of less than 5 seconds, and energy means (50) for powering the sensor system (30).. . ... Cordis Corporation

06/28/18 / #20180179262

Compounds suitable for treatment of haemophilia

The present invention relates to vwf compounds as well as compositions suitable for treatment of blood clotting diseases.. . ... Cordis Corporation

06/28/18 / #20180177952

A piston washer for a drug delivery device and drug delivery device incorporating such piston washer

The present invention relates to a piston washer (109, 209) for use in a drug delivery device for transferring a distally directed axial force from a piston rod (107, 207) towards a piston (199, 299) of a held cartridge (189, 289). The piston washer (109, 209) defines a proximal surface portion (109a) adapted for engagement with the distal portion of a piston rod (107, 207) and a distal surface portion (109b) configured to engage and abut a piston (199, 299). ... Cordis Corporation

06/21/18 / #20180169190

Insulin containing pharmaceutical compositions

The present invention is in the field of pharmaceutical compositions for the treatment of medical conditions relating to diabetes. More specifically the invention provides pharmaceutical compositions comprising a long-acting acylated derivative of a human insulin analogue, and to the medical use of such compositions for basal insulin administration therapy.. ... Cordis Corporation

06/14/18 / #20180161506

Drug delivery device with priming mechanism

The present invention relates to a drug delivery device for expelling a dose of drug from a held cartridge and that defines a distal drug outlet end and an opposite proximal end. The drug delivery device comprises: a distal housing component (110) holding a cartridge (113) comprising a liquid drug and a piston slideable arranged therein in an axial direction, and a proximal housing component (101) housing a dose setting and expelling mechanism comprising a piston rod for exerting a force on the piston of the cartridge (113) in a distal direction for expelling a dose. ... Cordis Corporation

06/14/18 / #20180161503

Drug delivery device with end-of-dose trigger arrangement

A drug delivery device comprising a rotatable scale drum, a trigger member, an actuation member, a trigger spring acting on the trigger member and being energized by movement of the actuation member, as well as an end-of-dose switch adapted to be actuated by movement of the trigger member. The trigger member is adapted to be arranged in an axially supported position against the action of the energized trigger spring, and released from the axially supported position when the scale drum is rotated from a set position to an end-of-dose position, whereby the trigger member is moved axially by the trigger spring, the end-of-dose switch thereby being actuated.. ... Cordis Corporation

06/14/18 / #20180161338

Retosiban for the treatment of pre-term labour

The present invention relates to a method of treating pre-term labour with retosiban in subjects with conditions resulting in uterine overdistension including polyhydroamnios and multiple gestation. In another aspect, the invention relates to a method of preventing pre-term labour in subjects by the prophylactic administration of retosiban.. ... Cordis Corporation

06/14/18 / #20180160692

Fish delivery device, fish-transfer system equipped with said fish delivery device, and method for the automated delivery of fish to a fish processing device

A fish feed-in device (1) for feeding fish (9) to a fish processing device (7) comprises a delivery conveying means (3) which is equipped with a controllable positioning drive (35) and a controllable conveying drive (36). The delivery conveying means (3) can be moved by the controllable positioning drive (35) into a first state (301) released by the fish (9) in a deposit space (11), into a second state (302) for grasping, centred holding and conveying of the fish (9) accessing said fish in the deposit space (11) and, in cooperation with the controllable conveying drive (36), into a third state (303) which releases the fish (9) after conveying at a fish delivery point (42) which is defined by a controlled delivery time with associated controlled fish delivery speed.. ... Cordis Corporation

06/07/18 / #20180159133

A device and method of manufacturing high aspect ratio structures

To this end the electronic device comprising an electronic circuit equipped with a current collector formed by a metal substrate having a face forming a high-aspect ratio structure of pillars having an interdistance larger than 600 nm. By forming the high-aspect structure in a metal substrate, new structures can be formed that are conformal to curvature of a macroform or that can be coiled or wound and have a robust design.. ... Cordis Corporation

06/07/18 / #20180159017

Microscale sensor structure with backside contacts and packaging of the same

A microscale sensor structure is provided that enables backside electrical connection to flush-mounted microscale sensors without through-wafer-vias (twvs). A flush-mounted microscale sensor can be fabricated without twvs by providing a sensor support substrate with openings for electrical connection access to the backside of a device layer. ... Cordis Corporation

06/07/18 / #20180156103

Mounting interface for exhaust gas treatment assembly

An exhaust gas treatment assembly comprises a housing which is radially inwardly deformed in a clamping region to retain a block of ceramic or other material which may be arranged as a filter or catalyst within the housing. The clamping region is deformed to a first surface level and includes local protuberances which extend radially outwardly to a second surface level and support a mounting surface for mounting the assembly in a mounting connector. ... Cordis Corporation

06/07/18 / #20180154087

Drug delivery device with spring mechanism

A drug delivery device comprises an housing, an axially displaceable piston rod, a rotatable drive member, a spring housing, a torsion drive spring coupled to the spring housing respectively the drive member, dose setting means allowing a user to simultaneously set a dose amount to be expelled and strain the torsion drive spring correspondingly by rotation of the drive member, and a release member being axially moveable relative to the housing between a proximal initial position and an actuated distal release position. The spring housing is helically coupled to the housing such that the spring exerts a tangential force on the spring housing to thereby bias the spring housing in the proximal direction, whereby the spring housing thereby exerts a proximally directed biasing force on the release member. ... Cordis Corporation

06/07/18 / #20180153182

Apparatus and method for automatically obtaining flesh from beheaded and gutted fish

The invention relates to an apparatus (10) for automatically recovering flesh from beheaded and gutted fish (11), comprising a transport device (12) for transporting the fish (11) tail-first along a transport path in transport direction t, and a separating device (14) for separating the flesh from the bone structure, wherein the separating device (14) has at least two rotatably driven and controllable circular knives (15, 16) which are arranged at a distance from each other on mutually opposing sides of the transport path in order to form a gap s; the invention is distinguished in that the two circular knives (15, 16) are designed such that the circular knives can each be pivoted about an axis i, ii that differs from a horizontal orientation, wherein the axes i, ii are oriented in such a way that, by pivoting the circular knives (15, 16) about the axes i and ii, the point p of the smallest gap size between the circular knives (15, 16) can be positioned differently from the lowest knife point m of the two circular knives (15, 16). The invention further relates to a corresponding method.. ... Cordis Corporation

05/31/18 / #20180150630

Authentication methods and systems

The invention provides a solution for secure authentication of an individual. The invention comprises methods and apparatus for secure input of a user's identifier e.g. ... Cordis Corporation

05/31/18 / #20180150629

Encoding methods and systems

The invention provides a solution for secure input of a user's input into an electronic device. The invention comprises methods and apparatus for secure input of a user's identifier e.g. ... Cordis Corporation

05/31/18 / #20180147364

Drug delivery device with multifunctional bias structure

The present invention provides a drug delivery device comprising a housing (2) extending along a longitudinal axis, a dose dial member (3) being rotatable relative to the housing (2) to set a dose of drug to be expelled from an attached reservoir and comprising a first serrated transversal surface (7), a second serrated transversal surface (16) being axially and rotationally fixed with respect to the housing (2), and being configured for slipping engagement with the first serrated transversal surface (7) in a bi-directional ratchet interface in response to the dose dial member (3) being rotated relative to the housing (2) to increase or decrease the dose, and a dose delivery mechanism for expelling a set dose, the dose delivery mechanism comprising a piston rod (50), a torsion spring (30) for providing energy to drive the piston rod (50), an activation button (8) being axially movable relative to the housing (2) between an inactivated position in which the torsion spring (30) is retained and an activated position in which the torsion spring (30) is released to cause an expelling of the set dose, the activation button (8) being biased towards the inactivated position by a bias structure (40) arranged to act between the dose dial member (3) and the activation button (8), the bias structure (40) thereby further biasing the first serrated transversal surface (7) towards the second serrated transversal surface (16), and a drive member (20) being rotationally biased by the torsion spring (30), wherein the drive member (20) is axially fixed to the activation button (8) and axially movable relative to the housing (2) between a dose setting position in which the drive member (20) is rotationally fixed to the dose dial member (3) and a dose expelling position in which the drive member (20) is rotationally freed from the dose dial member (3) and rotationally interlocked with the piston rod (50).. . ... Cordis Corporation

05/31/18 / #20180147363

A housing for a medical injection device

The invention relates to a medical injection device having a polymeric housing or housing parts. The housing comprises a moulded outer housing element and a moulded elongated tubular inner housing element. ... Cordis Corporation

05/24/18 / #20180142227

Coagulation factor vii polypeptides

The present invention relates to modified coagulation factor vii polypeptides exhibiting increased resistance to antithrombin inactivation and enhanced proteolytic activity. The present invention also relates to polynucleotide constructs encoding such polypeptides, vectors and host cells comprising and expressing such polynucleotides, pharmaceutical compositions, uses and methods of treatment.. ... Cordis Corporation

05/24/18 / #20180140776

Method for assembling a drug delivery device and drug delivery device formed by the method

The present invention relates to a method of assembling a drug delivery device which in the assembled state defines a distal housing component (102) that houses a piston equipped cartridge (189), and a proximal housing component (101) that houses a dose setting and expelling mechanism. The method includes the steps of arranging the cartridge (189) in the distal housing component (102), arranging a nut element (140) threadedly engaged with a piston rod (107) in the distal housing component (102), and securing the nut element (140) relative to the distal housing component (102) into a selective one of a series of predetermined relative orientations for obtaining a predetermined axial clearance or abutment between the piston rod (107) and the piston of the cartridge (189). ... Cordis Corporation

05/24/18 / #20180140673

Fgf21 derivatives and uses thereof

The invention relates to a derivative of a fgf21 protein having a cysteine residue at a position corresponding to position 167, 169, 170, 171, 172, 173, 174, 175 and in particular position 180 or position 181 of mature human fgf21 and derivatives thereof having a side chain attached to this cysteine. The fgf21 derivatives of the invention display high potency towards the fgf receptors. ... Cordis Corporation

05/17/18 / #20180133018

Apparatus for trialing a modular humeral head

The present disclosure is directed to a modular shoulder prosthesis measuring device having an adjustable radial offset provided by relative rotation of an adapter interdisposed between the stem and the head. Specifically, the interface configuration between the stem and the adapter, as well as between the adapter and the head are designed such that relative positioning of these components provides a continuous adjustment in the radial offset. ... Cordis Corporation

05/10/18 / #20180126089

Injection device with a sliding scale

The present invention relates to an injection device for automatic spring driven injection of a liquid drug. The injection device has a dose setting mechanism by which doses of an individual size can be set by a user, and a mechanical dose size display for displaying the size of the set dose. ... Cordis Corporation

05/10/18 / #20180126088

Rotary sensor arrangement for drug delivery device

A rotary sensor assembly comprises an indicator member adapted to rotate and having first and second axial positions, input means adapted to be actuated by movement of the indicator member, and a processor adapted to receive input from the input means. The indicator member comprises a plurality of actuator structures, and the input means comprises one or more switches adapted to be actuated by an actuator structure. ... Cordis Corporation

05/10/18 / #20180125946

Treating diabetes melitus using insulin injections administered with varying injection intervals

The present invention relates to methods for treatment of a condition or disease where administration of insulin will be of benefit, comprising administering, to a patient in need thereof, effective dosages of an insulin, insulin analogue or derivative thereof, which exhibits a prolonged profile of action, wherein said dosages are administered at intervals of varying length.. . ... Cordis Corporation

05/10/18 / #20180125470

Patent foramen ovale closure method

The present invention relates to devices for closing a passageway in a body, for example a patent foramen ovale (pfo) in a heart, and related methods of using such closure devices for closing the passageway. The method includes introducing a mechanical closure device into an atrium of the heart and transeptally deploying the closure device across the interatrial septum to provide proximation of the septum secundum and septum primum.. ... Cordis Corporation

05/10/18 / #20180124990

Drum style rotary tiller

A rotary tiller comprises a frame, a cylindrical drum rotatable relative to the frame, a plurality of tines extending from the cylindrical drum, a motor at least partially disposed within the cylindrical drum, wherein the motor is configured to rotate a motor output member, and a transmission at least partially disposed within the cylindrical drum and configured to engage the motor output member. The transmission is operable to drive rotational movement of the cylindrical drum.. ... Cordis Corporation

05/03/18 / #20180120361

Method for preventing battery overcharge and overdischarge and increasing battery efficiency

A battery power table setting method for using battery power efficiently and preventing battery overcharge includes: a first table generation operation for generating a first table by measuring a maximum charging power that prevents an output of a battery from being more than a maximum allowable voltage when the battery having a predetermined soc value is charged at a predetermined temperature for a predetermined time; a second table generation operation for generating a second table by measuring an soc value at the time point that the battery reaches the maximum allowable voltage when the battery is charged with a predetermined power value at a predetermined temperature; a third table generation operation for generating a third table by calculating a second maximum charging power according to a predetermined temperature and a predetermined soc value based on the second table; and a derating table generation operation for generating a derating table.. . ... Cordis Corporation

05/03/18 / #20180117259

Power efficient electronic device

An assembly comprises an electric consumer, an electric voltage source adapted to power the electric consumer, and user operated actuation means. The electric voltage source is operatable between a first state in which a first voltage is generated and a second state in which a second higher voltage is generated. ... Cordis Corporation

05/03/18 / #20180117240

A medical injection device with telescopically movable needle shield having a cleaning chamber for the needle

The invention relates to a pre-filled injection device for apportioning set dose of a liquid drug. The housing of the pre-filled injection device internally supports a non-replaceable cartridge (160) having an hollow interior containing a liquid preservative containing drug and externally supporting a removable protective cap (150). ... Cordis Corporation

05/03/18 / #20180117133

Tolerogenic dna vaccine

The present invention relates to plasmids useful for prevention and/or delay of e.g. Type 1 diabetes.. ... Cordis Corporation

04/19/18 / #20180105594

Antibodies against human nkg2d and uses thereof

The present invention provides isolated anti-human nkg2d monoclonal antibodies useful for therapeutic applications in humans. Typically, the antibodies are fully human or humanized to minimize the risk for immune responses against the antibodies when administered to a patient. ... Cordis Corporation

04/19/18 / #20180104335

Stable multi-dose compositions comprising an antibody and a preservative

The invention relates to stable, multi-dose liquid compositions containing proteins, in particular, but not exclusively stable antibodies, and to the use of said compositions in therapy, in particular for the subcutaneous delivery of said stable protein.. . ... Cordis Corporation

04/12/18 / #20180102094

Pixel array and circuit for virtual reality

The invention relates to the field of display, more specifically, to a pixel array and a display circuit for virtual reality. In the invention, two transistors (i.e., a third transistor and a fourth transistor) are respectively connected in parallel to two ends of the two transistors (i.e., the first transistor and the second transistor) controlled by the first enable signal, and as the enable signal accessed the first transistor and the second transistor is a line-by-line scan, and the enable signal accessed the third transistor and the fourth transistor can drive each of the display devices in the a plurality of rows of pixel circuits to be lit at the same time.. ... Cordis Corporation

03/29/18 / #20180090065

Transmitting control line driver, oled panel having same, and display device

A transmitting control line driver, an oled panel having same, and a display device. The transmitting control line driver comprises multiple stages of transmitting control line driver units. ... Cordis Corporation

03/29/18 / #20180085533

Electroformed needle cannula

Disclosed herein is a method of electroforming a needle cannula (100) for an injection device, wherein the electroforming method is performed in an electroforming system (1) comprising a cathode (10), an anode (60) and an electrolyte (50) with dissolved metal ions, wherein the method comprises providing a permanent mandrel (10), wherein the mandrel is configured to constitute the cathode. The mandrel (10) comprises a forming portion (20) having a forming surface (21, 22, 23, 24, 25, 26) adapted to form an inner surface of the needle cannula (100), wherein the forming portion (20) comprises a cylindrical axis (a), a longitudinal extension, a first proximal end (16) and a second distal end (17). ... Cordis Corporation

03/29/18 / #20180085439

Stabilised solid compositions of factor vii polypeptides

The invention relates to chemically as well as physically stable compositions comprising factor vii or a factor vii-related polypeptide such that these compositions can be stored, handled and used at room temperature.. . ... Cordis Corporation

03/29/18 / #20180085435

Use of long-acting glp-1 peptides

The invention relates to use of long-acting glp-1 peptides in certain dosage regimes for the treatment of type 2 diabetes, obesity, etc.. . ... Cordis Corporation

03/22/18 / #20180078168

Device for processing and visualizing data of an electrical impedance tomography apparatus for determining and visualizing regional properties of pulmonary ventilation

A great device (10) processes and visualizes electrical impedance tomography (eit) data (3) of at least one region of the lungs for determining and visualizing regional properties of the lungs of a living being. The eit data (3) are obtained from an electrical impedance tomography apparatus (30). ... Cordis Corporation

03/15/18 / #20180071458

Cartridge holder assembly for drug delivery device

. . A cartridge holder assembly is provided, comprising an enclosed cartridge, a distal portion and a proximal portion. The enclosed cartridge defines a longitudinal axis and comprises a generally cylindrical main portion, a distal outlet portion having a neck portion with a circumferential shoulder portion, and a proximal portion having an opening surrounded by a circumferential rim. ... Cordis Corporation

03/08/18 / #20180064880

Drug delivery device with dose reset mechanism

Drug delivery device adapted to expel a set dose, comprising an expelling mechanism with a drive spring, a dose setting mechanism with first and second dose setting ratchet parts, a bias spring as well as control means. The control means is adapted to rotate the second ratchet part in a first direction to thereby set a dose when rotating the dose setting member in the first direction, and move the ratchet parts axially out of engagement with each other when the dose setting member is rotated in the opposite direction. ... Cordis Corporation

03/08/18 / #20180064878

Deformable piston washer

The present invention provides a piston washer (1, 51) for a drug delivery device, the piston washer (1, 51) comprising a central portion (2, 72) arranged about a centre axis, a peripheral portion (3, 73), and an axially pliable structure (8, 78) connecting the central portion (2, 72) and the peripheral portion (3, 73). The axially pliable structure (8, 78) is preconfigured to undergo permanent deformation in response to a difference between a first resultant force acting on the peripheral portion (3, 73) and a second resultant force acting on the central portion (2, 72) exceeding a threshold level. ... Cordis Corporation

03/01/18 / #20180057566

O-linked glycoforms of polypeptides and method to manufacture them

The present invention relates to compositions comprising glycoproteins having altered patterns of o-linked glycosylation, in particular factor vii, factor ix, and methods for making these.. . ... Cordis Corporation

02/15/18 / #20180044394

Stable, protracted glp-1/glucagon receptor co-agonists for medical use

The invention relates to novel stable and protracted glp-1/glucagon receptor co-agonists, to the use of said peptides in therapy, to methods of treatment comprising administration of said peptides to patients, and to the use of said peptides in the manufacture of medicaments.. . ... Cordis Corporation

02/08/18 / #20180036484

Accessory device with mounting safety feature

A medial assembly comprises a logging first unit adapted to be mounted on a drug delivery device second unit from a fully un-mounted to a fully mounted position along a path. The first unit comprises a switch operatable between an off- and an on-state when the first unit is mounted on the second unit, the switch being in the on-state when the first unit is mounted within a first distance from the fully mounted position, and in the off-state when the first unit is mounted outside the first distance from the fully mounted position, and a snap lock operatable from an initial state through an expanded state to a snap-in state when the first unit is mounted on the second unit, the snap lock being in the snap-in state when the first unit is mounted within a second distance from the fully mounted position, the second distance being shorter than the first distance. ... Cordis Corporation

02/01/18 / #20180033999

Flexible organic light emitting device and method of manufacturing the same

The present disclosure provides a flexible organic light emitting device and a method of manufacturing the same. The flexible organic light emitting device includes: a flexible array substrate; an organic light emitting device layer, formed on a side of the flexible array substrate; an aluminum oxide layer, formed on a side of the organic light emitting device layer away from the flexible array substrate; at least one composite water and oxygen barrier layer, formed on a side of the aluminum oxide layer away from the organic light emitting device layer and including a mica foil and a polymer layer, the mica foil being provided on a side of the polymer layer toward the aluminum oxide layer; and a polarizing layer with a touch electrode, formed on a side of the composite water and oxygen barrier layer away from the aluminum oxide layer.. ... Cordis Corporation

02/01/18 / #20180033370

Pixel circuit and method for driving the same

The present disclosure relates to a pixel circuit and a method for driving the same. The pixel circuit includes: first and second transistors, control terminals of which receive a first scan signal; third and fourth transistors, control terminals of which receive a second scan signal; a fifth transistor, a control terminal of which is electrically coupled to a capacitor; sixth, seventh and eighth transistors, control terminals of which receive a control signal; and a light emitting diode. ... Cordis Corporation

02/01/18 / #20180029736

Changeover device applicable on packaging machines with flexible wrapping material

A changeover device for an intermittent packaging machine with wrapping material constituted by a flexible film for successive welding, forming and work operations of envelopes for containing the packed product, comprises a plurality of mobile stations at adjustable interdistances, designed for performing, in succession, operations of welding, forming and processing of the envelopes (including different envelope formats), each of which is constituted by a substantially vertically-arranged frame, slidably positioned on fixed guide rails. The machine is equipped with a changeover device in which each single station is provided with a brake group able to maintain the single station blocked in a predetermined position along all the work line. ... Cordis Corporation

02/01/18 / #20180029246

Cutting/portioning using combined x-ray and optical scanning

A processing system (10) and corresponding method (158) are provided for processing workpieces (wp), including food items, to cut and remove undesirable components from the food items and/or portion the food items while being conveyed on a conveyor system (12). An x-ray scanning station (14) is located on an upstream conveyor section (20) to ascertain size and/or shape parameters of the food items as well as the location of any undesirable components of the food items, such as bones, fat or cartilage. ... Cordis Corporation

02/01/18 / #20180027848

Apparatus for acquiring and analysing product-specific data for products of the food processing industry as well as a system comprising such an apparatus and a method for processing products of the food processing industry

The invention relates to an apparatus (10), designed and configured to acquire and analyse product-specific data for products (12) of the food processing industry, comprising a conveyor (11), which is gap-free in the transport plane, for transporting separated products (12) in transport direction t from an intake end to a discharge end, an x-ray unit (13) having at least one x-ray source (14) and at least one x-ray camera (15) for acquiring product-specific data, wherein x-ray source (14) and x-ray camera (15) are assigned to the conveyor (11) in such a manner that the products (12) can be guided along between the x-ray source (14) and the x-ray camera (15), as well as a control unit (16) which is connected to the x-ray unit (13) and is designed and configured to receive and analyse the product-specific data, forming a first data set, acquired by said x-ray unit (13), which is characterised in that at least one optical camera (17) is assigned to the same conveyor (11) between its intake end and discharge end, by means of which, in addition to the x-ray unit (13), product-specific data of the products (12) transported on said conveyor (11) can be acquired, wherein the optical camera (17) is connected to a control unit (18) which is designed and configured to receive and analyse the product-specific data, forming a second data set, acquired by the optical camera (17). The invention also relates to a system (29) comprising such an apparatus (10) as well as a method for processing products (12) of the food processing industry.. ... Cordis Corporation

01/25/18 / #20180026435

Dc breaker

A dc breakers and in particular to dc breaker modules suitable for use in a high voltage dc circuit. The breaker module comprises at least a first breaker circuit (enclosed within a conductive enclosure. ... Cordis Corporation

01/25/18 / #20180026259

Mixed redox couple electrodes for rate capability and overdischarge protection

A composite electrode is a composite of conductive materials of at least a first material and a second material, wherein the first material undergoes a parasitic reaction in a region where the second material is stable, and the first material and second material are stable at the first material's nominal voltage. An exemplary electrode is a cathode comprising lithium manganese oxide (lmo) and lithium iron phosphate (lfp).. ... Cordis Corporation

01/25/18 / #20180026232

Thin-film package for organic light-emitting diode, organic light-emitting diode, and organic light-emitting display

The present invention relates to a thin-film package for an organic light-emitting diode, an organic light-emitting diode using the thin-film package, and an organic light-emitting display. The thin-film package includes at least one inorganic film layer and at least one organic film layer, the inorganic film layer and the organic film layer being alternately stacked; the inorganic film layer is made of a material selected from any one of poly(silicon nitride), poly(silicon oxide), poly(silicon carbonitride), poly(silicon carbooxide), poly(silicon carbonitride) and poly(silicon carbonitrideoxide), or any combination thereof; and the organic film layer is made of a material selected from any one of acrolein-based polymer, silicon-based polymer and epoxy-based polymer, or any combination thereof. ... Cordis Corporation

01/25/18 / #20180026219

Organic light emitting element, display panel and display device

The present disclosure relates to an organic element, a display panel and a display device. The organic light emitting element includes: a first electrode; a hole layer disposed on the first electrode; a light emitting layer including a first light emitting portion, a second light emitting portion and a third light emitting portion; an electron layer on the light emitting layer; and a second electrode disposed on the electron layer. ... Cordis Corporation

01/25/18 / #20180026117

Display device

The present disclosure provides a display device, including: a gate line and a data line; a pixel array; a gate driver, configured to provide a gate signal to the gate line; a test circuit, coupled to a first input line and a second input line respectively; and a data driver, including a first power line, a first transistor and a third input line, wherein the first power line is configured to supply an initial voltage to the pixel array, the first power line is coupled to the first input line via the first transistor, a gate of the first transistor is coupled to the third input line, the third input line is configured to transmit a pre-charge control signal, and the pixel array is configured to supply the initial voltage to each pixel in the pixel array based on the pre-charge control signal.. . ... Cordis Corporation

01/18/18 / #20180016326

Antibodies that bind peptidoglycan recognition protein 1

Disclosed herein is a method for identifying trem-1's ligand and antibodies, or fragments thereof, which are capable of modifying the function of trem-1's ligand. Antibodies that reduce or block trem-1 activation may be identified and selected using this method. ... Cordis Corporation

01/18/18 / #20180016319

Acylated glucagon analogues

The present invention relates to novel peptide compounds which have an improved physical stability in solution and improved solubility at neutral ph, to the use of the compounds in therapy, to methods of treatment comprising administration of the compounds to patients in need thereof, and to the use of the compounds in the manufacture of medicaments. The compounds of the invention are of particular interest in relation to the treatment of hyperglycemia, diabetes and obesity, as well as a variety of diseases or conditions associated with hyperglycemia, diabetes and obesity.. ... Cordis Corporation

01/11/18 / #20180011562

Touch display panel and method for manufacturing the same

A touch display panel and a method for manufacturing the same are provided. The touch display panel includes a flexible substrate, a light emitting device, an encapsulating film and a touch sensing device. ... Cordis Corporation

01/04/18 / #20180001033

An injection needle assembly for an injection device and an injection device comprising such assembly

An injection needle assembly (50) for an injection device, comprising: a) a needle cannula (3) attached to a needle hub (4) and defining a pointed tip at a free end (3a, 3b), and b) a needle cover (10, 10a, 10b) forming an axially extending elongated flexible enclosure accommodating the needle cannula (3). The needle cover (10, 10a, 10b) is configured to axially collapse and become penetrated by the needle cannula (3) when a penetration force is applied to the needle cover. ... Cordis Corporation

01/04/18 / #20180001030

A piston rod drive for an injection device

The invention relates to a piston rod drive arrangement for an injection device used for self-administration of a plurality of individually set doses. The drive arrangement is made from a first element (10) mating the non-circular cross-section (3) of a piston rod (1) and a second element (20) having an inner thread (21) mating the outer thread of the piston rod. ... Cordis Corporation

01/04/18 / #20180000935

Stable antibody containing compositions

The invention relates to stable and low viscous (<50 cp) protein containing compositions, in particular, but not exclusively stable antibody containing compositions and to the use of said stable proteins in therapy, in particular for the subcutaneous delivery of said stable protein.. . ... Cordis Corporation

01/04/18 / #20180000903

Tablets comprising glp-1 agonist and enteric coating

The present invention relates to solid pharmaceutical compositions for oral administration comprising a glp-1 agonist, an absorption enhancer which is a salt of medium-chain fatty acid, and an enteric coating as well as uses thereof.. . ... Cordis Corporation

01/04/18 / #20180000742

Pharmaceutical composition for oral insulin administration comprising a tablet core and a polyvinyl alcohol coating

The present invention relates to a solid oral insulin composition comprising a salt of capric acid which enhances the bioavailability and/or the absorption of said acylated insulin in combination with a polyvinyl alcohol coating, which is soluble in aqueous media independent of ph.. . ... Cordis Corporation

12/28/17 / #20170371366

Low dropout linear voltage regulator with compensation

The present disclosure provides a low dropout linear voltage regulator, including: an amplifier, configured to have a first input end receiving a reference voltage, a second input end configured to receive a feedback voltage, and an output end connected to a first node; an output transistor, having a control end connected to the first node, a first end connected to a first power source potential, and a second end connected to a second node and configured to provide an output voltage; a feedback circuit, connected to the second node and configured to provide the feedback voltage according to the output voltage; and a compensation circuit, comprising at least one of a first compensation amplifier, a second compensation amplifier and a first variable current source. The compensation circuit detects and suppresses a voltage transient generated when a load switching from light to heavy occurs at the second node.. ... Cordis Corporation

12/28/17 / #20170369905

N-glycosylation

The present invention relates to a mammalian cell comprising a gene encoding a polypeptide of interest, wherein the polypeptide of interest is expressed comprising one or more posttranslational modification patterns. These modifications are useful for example in glycoprotein production where the antibodies with the modifications have an enhanced antibody-dependent cell-mediated cytotoxicity (adcc). ... Cordis Corporation

12/21/17 / #20170361207

Internally illuminable playing cards

Internally illuminable playing cards are disclosed. The disclosed playing cards may include a polymeric body, at least one light-emitting diode (led) at least partially inside of the polymeric body, a battery (or a slot in the polymeric body for receiving a battery) for providing power to the at least one led, and a switch at least partially inside the polymeric body and operatively connected to the at least one led to facilitate turning the at least one led on and off. ... Cordis Corporation

12/21/17 / #20170361029

An injection needle assembly for an injection device and an injection device comprising such assembly

An injection needle assembly (50) for an injection device, comprising: a) a needle cannula (3) attached to a needle hub (4) and defining a pointed tip at a free end (3a, 3b), and b) a needle cover (10, 10a, 10b) forming an axially extending elongated flexible enclosure accommodating the needle cannula (3). The needle cover (10, 10a, 10b) is configured to axially collapse and become penetrated by the needle cannula (3) when a penetration force is applied to the needle cover. ... Cordis Corporation

12/14/17 / #20170358261

Display device, pixel driving circuit and driving method thereof

The present disclosure relates to a display device, a pixel driving circuit and a driving method thereof. The oled pixel driving circuit includes an electroluminescent devices, first to seventh switching elements and a storage capacitor. ... Cordis Corporation

12/14/17 / #20170358259

Pixel circuit and light emitting display device

A pixel circuit includes: a light emitting component, a first transistor (mt2) including a gate coupled to a first node (n1), a first terminal coupled to a first pixel power supply (velvdd) and a second terminal coupled to a second node (n3), and the pixel current flows from the first terminal to the second terminal in response to a voltage at the gate; a second transistor (mt1), for selectively providing a data signal to a third node (n2); a third transistor (mt3); a fourth transistor (mt6), for selectively providing a compensation voltage to the first transistor (mt2); a fifth transistor (mt5), for selectively providing an initialization voltage to the third node (n2); a sixth transistor (mt4), for selectively providing the pixel current to the light emitting component; and a capacitor (c1), located between the first node (n1) and the third node (n2).. . ... Cordis Corporation

12/14/17 / #20170355974

Factor vii conjugates

The present invention relates to the conjugation of factor vii polypeptides with heparosan polymers. The resultant conjugates may be used to deliver factor vii, for example in the treatment or prevention of bleeding disorders.. ... Cordis Corporation

12/14/17 / #20170354713

Fgf21 derivatives and uses thereof

The invention relates to a derivative of a fgf21 protein having a cysteine residue at a position corresponding to position 167, 169, 170, 171, 172, 173, 174, 175 and in particular position 180 or position 181 of mature human fgf21 and derivatives thereof having a side chain attached to this cysteine. The fgf21 derivatives of the invention display high potency towards the fgf receptors. ... Cordis Corporation

12/07/17 / #20170348491

Handheld spring driven injection device with force regulation

A handheld injection device (10) comprising an needle cannula, a reservoir configured for containing a liquid drug to be dispensed, a piston, a trigger button (22), an elongated, hollow outer housing (20) in which the reservoir is positioned, the needle cannula being in liquid communication with the reservoir and extending from one end of the housing, wherein the injection device further comprises a drive mechanism comprising a spring or a resilient member, the spring or a resilient member being configured to provide a driving force when the trigger button is pressed allowing the piston to be advanced by the drive mechanism thus causing a dose of the liquid drug to be dispensed, wherein the handheld injection device comprises a variable friction system being adapted to apply a variable counter force leveling out the driving force.. . ... Cordis Corporation

12/07/17 / #20170348486

Drug delivery device with a hydraulic trigger mechanism

A device for administering a fluid medicament by injection comprises a dosing portion (1) with a collapsible reservoir (10). The reservoir (10) has a maximum volume in an extended state and a minimum volume in a collapsed state. ... Cordis Corporation

11/30/17 / #20170345876

Edge-to-edge mobile terminal

. . The present invention discloses a mobile terminal, comprising a bottom frame; a glass cover; a screen module covering the bottom frame; wherein the glass cover covers the screen module and two edges of both sides of the glass cover connect to the bottom frame; both the screen module and the glass cover have an arch opposite to the bottom frame; two edges of both sides of the screen module extend over both sides of the glass cover and are covered by the bottom frame. The beneficial effect of the above technical solution is: by utilizing the arch of the screen module and the glass cover opposite to the bottom frame, the front surface of the screen module and two sides of screen module do not have black edge, so that the display effect is excellent.. ... Cordis Corporation

11/30/17 / #20170343666

Detector of unauthorised objects or materials concealed in a shoe

The present invention relates to a detector device for detection of unauthorised objects or substances, comprising a support base (110) designed to receive at least one foot covered by its shoe, of an individual to be controlled, characterised in that it comprises in combination microwave sender/receiver means (140), measuring means (150) of the width of an element inserted in between the microwave sender/receiver means (140), analysis means of at least one parameter of the transmission time between the microwave sender/receiver means (140) and/or the amplitude of the signal transmitted between the microwave sender/receiver means (140), and standardisation means of the abovementioned analysis relative to a size unit of standard width obtained on the basis of the width-measuring means (150).. . ... Cordis Corporation

11/30/17 / #20170340836

A multi-state ratchet mechanism for drug injection devices

The present invention relates in a first aspect to a multi-state ratchet mechanism for a drug injection device. The multi-state ratchet mechanism comprises a ratchet gear member and a cooperating ratchet pawl member. ... Cordis Corporation

11/30/17 / #20170340808

Kit comprising a medical accessory device and a dummy unit

The invention provides a kit comprising a medical accessory device and a dummy unit. The accessory device comprises first attachment means configured for releasable attachment of the accessory to co-operating second attachment means on an original device having an outer surface defining an original device space envelope. ... Cordis Corporation

11/30/17 / #20170340807

Needle unit with a lockable needle shield and an injection device comprising such a needle unit

A needle unit (20) comprising: a needle hub (21) comprising a needle (23) and a needle shield (22), wherein the needle hub (21) and the needle shield (22) are arranged to form a needle unit (20) where the needle hub is arranged displaceably inside the needle shield such that the needle hub is displaceable along an axis which is parallel with the longitudinal axis of the needle (23) between a shielded position and an exposed position. The needle hub (21) further comprises a first hub locking element (24) and a second hub locking element (26) and the needle shield (22) further comprises a first shield locking element (25) and a second shield locking element (27), said first hub locking element (24) and said first shield locking element (25) engaging each other in the shielded position to establish a first releasable locking mechanism (24, 25) between the needle hub (21) and the needle shield (22), said second hub locking element (26) and said second shield locking element (27) engaging each other in the shielded position to establish a second locking mechanism (26, 27) between the needle hub (21) and the needle shield (22), both the first and second locking mechanisms (24, 25, 26, 27) being arranged as shock proof locks, and where the first releasable lock mechanism (24, 25) is arranged to engage with the lock release element (31) of the injection device (1) when the needle unit (20) is coupled to the injection device, said engagement allowing the first releasable lock mechanism (24, 25) to be unlocked. ... Cordis Corporation

11/23/17 / #20170338864

A wireless data communication module for drug injection devices

The present invention relates to a wireless data communication module (100) for a drug injection device. The wireless data communication module (100) comprises a folded flexible carrier member (107) comprising a plurality of stacked component support regions (203, 205, 207, 209, 211) and a display (103), such as a lcd or oled display, electrically connected to a first component support region (203) of the folded flexible carrier member (107) via a first set of electrical connection terminals. ... Cordis Corporation

11/23/17 / #20170334971

Alpha-1-antitrypsin (a1at) fusion proteins and uses thereof

The invention relates to mic-1 fusion proteins. More specifically it relates to compounds comprising fusion proteins comprising a mic-1 protein or an analogue thereof at the c-terminus of the fusion protein and a functional variant of human a1at (a1at) at the n-terminus of the fusion protein connected via a peptide linker. ... Cordis Corporation

11/23/17 / #20170333639

Spring-driven drug delivery device

The present invention relates to a drug delivery device (100) comprising a housing (101), a threaded piston rod (102), a rotatable drive tube (103), a drive nut (104) in threaded engagement with the piston rod (102) and being rotationally locked but axially moveable relative to the drive tube (103), and a support member (105) arranged rotationally free on the piston rod (102), the support member (105) being axially locked relative to the housing (101) and arranged to allow the drive tube (103) to move axially. The device further comprises a compression drive spring (106) arranged between the piston rod (102) and the drive tube (103), the compression drive spring (106) being arranged axially between the drive nut (104) and the support member (105).. ... Cordis Corporation

11/23/17 / #20170333514

Probiotic fermented cereal compositions and methods for treatment of gastrointestinal diseases caused by pro-inflammatory bacteria

The invention covers a novel treatment strategy that considerably improves conventional probiotic treatments of inflammatory bowel diseases, irritable bowel syndrome and other gastrointestinal disorders. Both probiotic microorganisms and the carrier of the probiotic microorganisms in form of a fermented cereal gruel are used as treatment effectors. ... Cordis Corporation

11/16/17 / #20170331161

Battery device, and protection method thereof

A battery device in one aspect of the present disclosure comprises a battery, a cell voltage monitoring part, a power supply line, a plurality of monitor lines, and an interrupter. The interrupter interrupts the power supply line and all of the plurality of monitor lines when the battery enters an overdischarge state.. ... Cordis Corporation

11/16/17 / #20170330512

Organic light-emitting diode display device

An oled display device includes an array of pixel units. Each pixel unit includes a pixel driving circuit and an oled. ... Cordis Corporation

11/16/17 / #20170326305

Needle assembly with needle hub shielding a needle cannula

A needle assembly (1) comprising a needle unit (2), where the needle unit (2) comprises a hub (6) with a skirt (3) having a longitudinal central axis (a), where the skirt (3) is having a proximal (7) and a distal end (8). The skirt is also having an internal surface adapted to interface with a mounting portion of a drug delivery device. ... Cordis Corporation

11/16/17 / #20170326302

Drug injection device with visual end-of-contents indicator system

Medical device (1) for injecting a set dose of an injectable product into a patient, the device having a cartridge containing the injectable product, a movable dosing driver (11) and a movable dose setting driver (15), and an end-of-contents indicator system (13) having counting means (17) with a counting part (19), and indication means (21) with a signal part (23), wherein the counting part (19) and the signal part (23) are formed with cooperating end-of-contents contact faces (25′, 25″), wherein the signal part (23) is movable between a first indication position and a second indication position, wherein the signal part (23) comprises a biasing means (33) for biasing the signal part (23) towards the first indication position, wherein the counting part (19) comprises a coupling (26), said coupling (26) is configured for operably connecting the counting part (19) to the dose setting driver (15), such that moving of the dose setting driver(15) towards increasing the set dose moves the contact face (25′) of the counting part (19) in relation to the contact face (25″) of the signal part (23) towards engagement of the contact surfaces (25′, 25″), and such that moving of the dose setting driver (15) towards decreasing the set dose moves the contact face (25′) of the counting part (19) away from the contact face (25″) of the signal part (23), wherein the counting part (19) is configured for providing engagement of the contact faces (25′, 25″) when the set dose reach the end-of-contents in the cartridge, and wherein the counting part (19) is configured for moving the signal part (23) towards the second indication position when the set dose is exceeding the end-of-contents in the cartridge. This way, if the user tries to dial a dose of drug beyond the amount remaining in the cartridge, an additional indication is given to the user via a distinctive area (41/43) of the signal part (23) becoming visible through a window (7) of the injector.. ... Cordis Corporation

11/16/17 / #20170325689

Method for monitoring dentition

A method for monitoring a property of the appearance of the teeth of a patient, said method including: a) acquiring, by means of a first acquisition apparatus, at least one first two-dimensional image of said teeth and of a first reference gauge, referred to as “initial image”; b) acquiring, by means of a second acquisition apparatus, at least one second two-dimensional image of said teeth and of a second reference gauge having the same appearance as the first reference gauge, referred to as “updated image”; c) standardising the initial and updated images such that the representations of the first and second reference gauges on the standardised initial and updated images have the same appearance; d) before or after step c, marking the same region of the teeth on the initial and updated images; and e) comparing the appearance of said region in the standardised initial and updated images.. . ... Cordis Corporation

11/09/17 / #20170324257

Power supply apparatus, protection apparatus, and protection method

When it has been determined according to a voltage detected by a voltage detecting unit 31 that a voltage detection line 23 between a focused-on battery 21 and the voltage detecting unit 31 has been broken, operations of each of switches 22 are controlled to separate a battery module 2 that includes the voltage detection line 23 from a power supply apparatus 1. When it has been determined according to the voltage detected by the voltage detecting unit 31 that the focused-on battery 21 has been overcharged or overdischarged, power input to, or output from, every battery module 2 is limited.. ... Cordis Corporation

11/09/17 / #20170320946

Receptor trem (triggering receptor expressed on myeloid cells) and uses thereof

Novel activating receptors of the ig super-family expressed on human myeloid cells, called trem(s) (triggering receptor expressed on myeloid cells) are provided. Specifically, two (2) members of trems, trem-1 and trem-2 are disclosed. ... Cordis Corporation

11/09/17 / #20170320927

Glp-1 derivatives and uses thereof

The invention relates to a derivative of a glp-1 analogue of a general formula i, which derivative comprises a side chain attached to a lys residue at position 34, 35, 36, 37, or 38 of the glp-1 analogue, which side chain comprises a branched linker, a 1st and a 2nd protractor selected from c18 diacid, c20 diacid, and sulfonic acid c16, and at least one linker element-1 incorporating ethylene glycol units. Linker element-1 may be incorporated in an optional pre-linker, and/or in a 1st or 2nd post-linker. ... Cordis Corporation

11/09/17 / #20170319790

Drug delivery device with air-in-cartridge safety feature

A drug delivery device adapted to receive a drug-filled cartridge (10), comprising dose setting means allowing a user to set a desired dose of drug to be expelled, an electronic controller (70,270) adapted to control a motor (51) to move a drive member to thereby expel an amount of drug from a received cartridge corresponding to a set dose, and means for estimating the amount of free air in a loaded cartridge. The controller is adapted to detect an error state if the estimated amount of free air in the cartridge is larger than or equals a given percentage of the amount of drug corresponding to a set dose.. ... Cordis Corporation

11/09/17 / #20170319664

Dosing regimen

The present invention relates to a long acting insulin analogue for use in reducing the risk of hypoglycaemia in a patient suffering from diabetes and requiring high amounts of delivered insulin, wherein the long acting insulin analogue is administered to said patient and in an amount of greater than 80 u/administration.. . ... Cordis Corporation

10/26/17 / #20170308244

Touch display panel

The present disclosure relates to a touch display panel. The touch display panel includes: a substrate including at least one first region and at least one second region which are disposed as adjacent to each other; a plurality of touch display units disposed on the substrate, wherein each of the plurality of touch display units includes: a driving element disposed in one of the at least one first region; an optical sensing member disposed in one of the at least one second region; a display device disposed on the driving element and the optical sensing member and electrically connected with the driving element; and a reflection layer disposed on the display device; wherein the optical sensing member is configured to sense light which is emitted from the display device to the reflection layer and reflected by reflection layer so as to sense a touch position.. ... Cordis Corporation

10/26/17 / #20170308195

Method for filtering touch noise and touch device

The present disclosure relates to a method for filtering touch noise and a touch device. The method includes: when normal signals for at least one row of the touch electrodes are input to the touch panel, obtaining a standard capacitance value of each of the touch electrodes, and obtaining a connection capacitance value of each of the touch electrodes; for each of the touch electrodes: subtracting a connection capacitance value of another touch electrode, which is in the same row with and adjacent to the touch electrode in a first direction, from the connection capacitance value of the touch electrode to obtain a capacitance difference value; from the last touch electrode, calculating the capacitance value of the restoration signal for each touch electrode along a second direction opposite to the first direction. ... Cordis Corporation

10/26/17 / #20170305994

Antagonistic dr3 ligands

The present invention relates to treatment of inflammatory diseases. In particular, the present invention relates to antagonistic dr3 ligands useful for treating inflammatory diseases.. ... Cordis Corporation

10/26/17 / #20170304208

A sustained-release formulation of metformin and a preparation method thereof

The present invention relates to a gastric-retention type sustained-release formulation of metformin as an insulin-independent diabetic agent, and a preparation method thereof. More specifically, the present invention relates to a gastric-retention type sustained-release formulation, which can effectively control drug release even with a small amount of a polymer by forming a sustained-release granulated material, which comprises granules containing metformin or a pharmaceutically acceptable salt thereof and a swellable polymer, and a water-insoluble coated on the surface of the granules; and also can allow a tablet containing the drug to swell rapidly at an early stage by formulating via mixing of a superdisintegrant, which is capable of controlling the speed of gelation forming hydrogels, with the granulated material; and a preparation method thereof.. ... Cordis Corporation

10/12/17 / #20170292859

Rotary sensor component and method of manufacture

A method of manufacturing a sensor member comprising the steps of arranging an initial sensor member in a fixed position relative to a material-removing tool, and control the tool to (i) remove material from the carrier alignment portion to thereby create an alignment structure, and (ii) remove material from at least one sensor layer area to thereby create a code segment pattern, each code segment thereby being aligned with the alignment structure.. . ... Cordis Corporation

10/12/17 / #20170291069

Multi-sensory and interdisciplinary balance platform training apparatus

This invention encompasses a balance board/wobbling platform type of apparatus which uniquely enables integrative training in two distinct realms not normally combined—namely, directly integrating physical balance with expressive musicality such that music itself can actually be created by the balancing adjustments of the user/s. In a direct sort of way, the user of the giant musical wobble board is actually enabled to create music by means of balance. ... Cordis Corporation

10/12/17 / #20170290988

An injection device adapted to detect air in a cartridge

A drug delivery device (100) for estimating the amount of free air in a cartridge (1) comprising a cartridge receiving portion (not shown) adapted to receive a cartridge (1), the cartridge (1) comprising a body portion (6), an axially displaceable piston (5), and a distal outlet portion (4), an expelling assembly comprising an axially displaceable piston drive member (10) adapted to interface with the proximal piston (5) portion of a received cartridge (1), the piston drive member (10) is adapted to be moveable in a distal direction, and to thereby pressurize the drug in a received cartridge. The drug delivery device further comprises means for measuring and acquiring a property relating to a fluid pres-sure of the drug in a received cartridge (1), and where the property depends on the amount of free air (7) contained in the cartridge (1). ... Cordis Corporation

10/12/17 / #20170290981

Drug delivery device with piston driver distal feature

Drug delivery device adapted to receive a cartridge, comprising drug expelling means with a piston driver comprising a distal end adapted to abut and axially move the piston of a loaded cartridge to thereby expel an amount of drug from the cartridge, and a motor assembly for moving the piston driver. The piston driver distal end comprises flexible centring means adapted to frictionally engage a cartridge inner surface proximally of the piston, thereby centring the cartridge and the piston driver distal end relative to the each other.. ... Cordis Corporation

10/05/17 / #20170288232

High solids content paste formulations for secondary battery electrode

A high solids content paste for fabrication of secondary battery electrodes may comprise: a negative active material or a positive active material; a binder; a solvent; and a hyperdispersant; wherein the high solids content paste has a specific viscosity chosen for a particular coating tool and a composition such that the high solids content paste will maintain a deposited shape after coating at least until the high solids content paste has dried and wherein the dry coating thickness is in the range of 5 microns to 300 microns. The high solids content paste with negative active material has a viscosity in the range of 30,000 cp to 45,000 cp and a corresponding density of 1.40 g/cc to 1.43 g/cc. ... Cordis Corporation

10/05/17 / #20170287400

Method and device of driving display and display device using the same

The present disclosure provides a method and a device of driving a display and a display device. The method includes: conducting first image data combined with image data relevant to the first image data in time/space by a micro disturbance operation processing, to obtain second image data; and outputting the second image data. ... Cordis Corporation

10/05/17 / #20170281809

Anti-nkg2a antibodies and uses thereof

Described herein are anti-nkg2a antibodies suitable for human therapy, including humanized versions of murine anti-nkg2a antibody z270, as well as related methods and materials for producing and using such antibodies. Exemplary complementarity-determining regions (cdrs) sequences and sites for optional amino acid back-substitutions in framework region (fr) and/or cdrs of such antibodies are also described.. ... Cordis Corporation

10/05/17 / #20170281785

Glycerol linked pegylated sugars and glycopeptides

The present invention provides conjugates between peptides and peg moieties through glycerol linkers.. . ... Cordis Corporation

09/28/17 / #20170277856

Healthcare risk extraction system and method

A healthcare risks extraction system comprising: a risk related terms collector to accept input of terms, the terms including terms related to risks in the form of potential diseases, terms related to risk factors that increase the likelihood of disease and terms related to treatments of a medical condition; a medical entity reconciliator, to standardise and expand the terms to include synonyms and equivalent terms using a standardised vocabulary of terms; a topic detector and tagger, to retrieve a set of documents linked to the expanded terms from a medical document database; a named entity recognition, resolution and disambiguation, nerd, module to extract entities from the set of document and each aligned to the standardised vocabulary; and a relation extractor to score relations between the entities based on the co-occurrence of two entities in documents in the retrieved set of documents; wherein the healthcare risks extraction system is arranged to generate a risk knowledge graph storing the entities and their scored relations.. . ... Cordis Corporation

09/28/17 / #20170274148

Drug delivery device with combined setting and release member

Drug delivery device has drive assembly adapted to move a piston rod in a distal direction, the drive assembly comprising a drive spring. A rotatable setting member allows a user to set a dose amount to be expelled, the drive spring being strained during dose setting. ... Cordis Corporation

09/28/17 / #20170273321

Device and method for shelling crabs

A crab butchering machine removes the carapace, mandibles and tail from a crab by timing actuation of tools depending upon the measured dimensions of the carapace. A measuring tool determines the location of the front and rear of the carapace relative to the saddle, securing and advancing the crab through the machine. ... Cordis Corporation

09/21/17 / #20170270343

Fingerprint recognition mechanism and electronic device

. . The present disclosure relates to a fingerprint recognition mechanism and an electronic device. The fingerprint recognition mechanism includes: a base plate; a cover plate disposed over and separated from the base plate; a touch panel disposed over the cover plate; and a fingerprint recognition unit disposed between the base plate and the cover plate to emit electrical signals and recognize biometric features; wherein the fingerprint recognition unit includes: a fingerprint module disposed below the cover plate and corresponding to a fingerprint sensing region of the touch panel; and a signal transmission layer electrically coupled with the fingerprint module and configured to transmit the electrical signals to a part of limbs of a user, wherein the electrical signals are transmitted to another part of the limbs through the user so that the fingerprint module recognizes biometric features of the another part of the limbs of the user.. ... Cordis Corporation

09/21/17 / #20170269766

Mobile device and method of distinguishing between different touch forces

The present disclosure provides a mobile device and a method of distinguishing between different touch forces. The method includes steps of: preloading an area of a maximum touch region with a maximum force, presetting a relationship among a current force, an area of a current touch region, the maximum force and the area of the maximum touch region, and presetting at least two force levels, wherein each of the at least two force levels corresponds to a respective range of a ratio of the current force to the maximum force; detecting and calculating the area of the current touch region of the touch component when touched; according to the relationship, calculating the ratio of the current force to the maximum force by using the area of the current touch region, so as to determine a corresponding one of the at least two force levels.. ... Cordis Corporation

09/21/17 / #20170269735

Flexible touch sensor and display device including the flexible touch sensor

This disclosure is related to the field of semiconductor technology, more specifically, to a flexible touch sensor and display device including the flexible touch sensor. The flexible touch sensor is formed through the construction of chain structure formed by flexible conductors and rigid conductors, that is, based on the principle of chains, connecting the rigid conductors and flexible conductors in an interval way, to form a chain structure, and making the manufactured sensor and the display device reach the purpose of being flexible, and the problem caused by the immature of the development of flexible materials that the flexible sensor can't be mass-produced can be effectively solved.. ... Cordis Corporation

09/21/17 / #20170266389

Accessory device with snap feature

A logging device adapted to be attached to a pen drug delivery device (210) and capture a property value related to the dose amount of drug expelled from the drug delivery device during an expelling event, the logging device comprising a bore in which a snap lock with a flexible wire portion is arranged circumferentially in the bore, the wire being adapted to be moved laterally by a projection on the pen device and subsequently snap inwardly when the pen device is inserted axially in the bore. In this way an axial snap lock is provided between the logging device and the drug delivery device.. ... Cordis Corporation

09/14/17 / #20170260289

Antibodies capable of binding two epitopes on tissue factor pathway inhibitor (1-161)

The application discloses bispecific tfpi antibodies that are capable of specifically and simultaneously binding two epitopes within tfpi (1-161). Such bispecific antibodies strongly enhance thrombin generation by neutralising tfpi, even where the concentration of tfpi is elevated. ... Cordis Corporation

09/14/17 / #20170259011

Torsion spring driven injection device

The present invention relates to a torsion spring driven injection device for delivering set doses of a liquid drug. The injection device mechanism is encapsulated in a housing which also stores the cartridge containing the liquid drug. ... Cordis Corporation

09/14/17 / #20170259010

Drive mechanism for an injection device

The invention relates to an injection device for self-administration of doses of a liquid drug. The injection device carries a needle cannula (15) which is concealed by a telescopically movable shield (20). ... Cordis Corporation

09/14/17 / #20170259005

Injection device with torsion spring and rotatable display

The present invention relates to an injection device comprising a torsion spring operatively connected to a dose setting member being adapted to set a dose to be ejected from the injection device. A rotatably mounted display member adapted to display the dose to be ejected in accordance with a setting of the dose setting member is also provided. ... Cordis Corporation

09/14/17 / #20170258999

Drug delivery device with cartridge centring feature

Drug delivery device adapted to receive a cartridge, comprising a piston driver adapted to expel an amount of drug from a received cartridge, and a base member adapted to engage a cartridge and position the cartridge relative to the piston driver, the base member comprising a main portion with a central passage, a portion of the piston driver being arranged axially displaceable through the passage, the piston driver distal end being arranged distally of the central passage, and flexible centring means adapted to receive the proximal end of a cartridge and centre it relative to the central opening and thereby to the piston driver.. . ... Cordis Corporation

09/14/17 / #20170258711

Fatty acid acylated d-amino acids for oral peptide delivery

The present invention relates to fatty acid acylated amino acids (fa-daa's) acting as permeation enhancers for oral delivery of therapeutic macromolecules such as peptides and pharmaceutical compositions comprising such fa-daa's.. . ... Cordis Corporation

09/07/17 / #20170252408

Liraglutide in cardiovascular conditions

The present invention relates to the glp-1 receptor agonist liraglutide for use in medicine.. . ... Cordis Corporation

08/24/17 / #20170239362

Growth hormones with prolonged in-vivo efficacy

The invention relates to growth hormone compounds with a protracted profile. The effect is obtained by linking an albumin binding residue via a hydrophilic spacer to growth hormone variants. ... Cordis Corporation

08/17/17 / #20170237708

Telecommunication system and method for traversing an application layer gateway firewall during the establishment of an rtc communication connection between an rtc client and an rtc server

The invention relates to a telecommunications assembly (10) and a method for traversing an application layer gateway firewall (40) during the establishment of an rtc communication connection between an rtc client (20) and an rtc server (30) using a proprietary rtc signalling protocol, wherein the firewall (40) has no specific knowledge of the proprietary rtc signalling protocol. The method comprises the following steps: the rtc client (20) and the rtc server (30) negotiate during the establishment of the rtc communication connection which of the ports (p1, p2, p3) of the firewall (40) are required for the data packets to be exchanged via the rtc communication connection, wherein they use at least one standardised message element as a component of the proprietary rtc signalling protocol, with which information relating to the ports to be used can be found; during the establishment of the rtc communication connection the firewall (40) detects, with the aid of the standardised message element, which of the ports (p1, p2, p3) of the firewall (40) are considered by the rtc client (20) and the rtc server (30) to be necessary for the data packets to be exchanged via the rtc communication connection; and the firewall (40) opens and closes the required ports (p1, p2, p3) in a dynamic manner according to the result of the negotiation.. ... Cordis Corporation

08/17/17 / #20170236878

Pixel array, display panel and pixel structure

A display panel, a pixel array and a pixel structure are provided in the present disclosure. The pixel array includes: a substrate; and a plurality of pixel units, each of the pixel units being disposed on the substrate and including: a first surface facing the substrate; a second surface opposite to the substrate; and a side wall connecting the first surface and the second surface, wherein the first surface has an area greater than that of the second surface, and light from each pixel unit exits from the second surface and the side wall.. ... Cordis Corporation

08/17/17 / #20170236469

Pixel compensation circuit and display device

The present disclosure relates to a pixel compensation circuit and display device. The circuit includes: first to fifth switching elements, a storage capacitor, and a driving element. ... Cordis Corporation

08/17/17 / #20170232203

Pen-type drug injector and add-on module with magnetic dosage sensor system and error detection

Add-on module (100) for logging the value of an expelled dose from a pen-type drug injector (200), comprising a magnetic sensor system comprising first and second sensor means (745/746) as well as a mechanical dose setting and expelling mechanism comprising a magnetic clutch element (240/740) which rotates during drug expelling. The system further comprises processor means configured to determine (i) on the basis of measured values from the first sensor means, a rotational position of the clutch element, (ii) on the basis of measured values from the second sensor means, a high-speed condition in which the rotational speed of the clutch element exceeds a given threshold level, and (iii) indicate an error state if the high-speed condition is detected.. ... Cordis Corporation

08/17/17 / #20170231993

Solid pharmaceutical compositions containing an integrase inhibitor

(b) an extragranular component comprising (i) a second superdisintegrant, (ii) a filler, and (iii) a lubricant. Methods for preparing the tablets and the use of the tablets, optionally in combination with other anti-hiv agents, for the inhibition of hiv integrase, for the treatment or prophylaxis of hiv infection, or for the treatment, delay in the onset, or prophylaxis of aids are also described.. ... Cordis Corporation

08/17/17 / #20170231239

Conveying and distributing apparatus for slaughtered fish

The present invention relates to a conveying and distributing apparatus for delivering fish slaughtered by means of a plurality of slaughtering machines to at least one distributing device, comprising longitudinal conveyors downstream of each of the slaughtering machines, which are configured to receive the slaughtered fish longitudinally in a head to tail orientation, wherein each of the longitudinal conveyors comprises a weighing device for detecting the weight of the slaughtered fish, at least one first transfer device is arranged on each of the longitudinal conveyors, which are designed and configured to transfer the slaughtered fish to at least one transverse conveyor, wherein the at least one transverse conveyor is adapted to receive the slaughtered fish transversely with respect to the head to tail orientation, a feed device arranged on the end of the transverse conveyor, which is designed and configured to remove the slaughtered fish from the transverse conveyor and to feed the same to a distributing device, and a control device, wherein the control device comprises a position tracking means for tracking the respective positions of slaughtered fish and an allocation means for allocating the detected weights to the respective tracked positions of the slaughtered fish, and wherein the control device is designed and configured to control the distributing device on the basis of the detected weights when the slaughtered fish enter the distributing device according to a predefined distribution rule. The invention further relates to a corresponding arrangement and a corresponding method.. ... Cordis Corporation

08/10/17 / #20170224927

Pen-type drug delivery device with electronic display on clip member

. . A portable pen-type drug injection device (300) comprises a main portion (301) and a clip (360). The clip comprises a base portion mounted to a portion of the drug delivery device, and a clip gripping portion with a free end. ... Cordis Corporation

08/10/17 / #20170224924

A stop mechanism for a hypocycloid end-of-content mechanism in an injection device

The invention relates to a stop mechanism for a non-axial working end-of-content mechanism which is geared by a hypocycloid gearing. The eoc mechanism comprises a stationary first element (10), an eoc element (30) and a rotational element (50) with a cam surface. ... Cordis Corporation

08/03/17 / #20170221578

Shift register unit, gate drive circuit, and display device

The present disclosure discloses a shift register unit, a gate drive circuit, and a display device. The shift register unit includes first to twelfth switch elements, a first capacitor, and a second capacitor. ... Cordis Corporation

08/03/17 / #20170220147

Method of amplifying touch control signal and touch control device using the same

The present disclosure provides a method of amplifying a touch control signal and a touch control device, applied to a touch control panel having a plurality of sensing points, including: acquiring capacitance values of at least one row of the sensing points of the touch control panel, and performing at least one round of amplifying steps, wherein each round of the amplifying steps includes subtracting a preset capacitance reference value from the capacitance value of each of the sensing points to obtain a capacitance difference value, and taking a product of amplifying the capacitance difference value by k times as a new capacitance value of the sensing point, where k is any number greater than or equal to 1. The method and the touch control may increase snr effectively and improve sensitivity of the touch control panel.. ... Cordis Corporation

07/27/17 / #20170209650

Logging device operated by drug delivery device

An add-on dose logging device for a pen device consumes energy when the sensors are operated and when the display is active. By using cap-off event to activate the sensor system only, and using cap-on event to de-activate the sensor system and activate the display for a given time to display a sensed dose, power consumption can be reduced without changing the user-interface and without adding any components apart from a switch.. ... Cordis Corporation

07/20/17 / #20170205771

Watch and method for manufacturing the same

The present disclosure relates to a watch and a method for manufacturing the same. The watch includes: a movement component; a display panel including: a first substrate disposed over the watch movement; a through hole passing through the display panel; a display element disposed on the first substrate and surrounding the through hole; and a package unit for packaging the display element and including at least a first package portion disposed on the first substrate, surrounding the through hole and located between the through hole and the display element so as to prevent external water or oxygen contacting the display element; a spindle disposed in the through hole and connected with the watch movement; and a pointer portion disposed over the display panel and connected with the spindle.. ... Cordis Corporation

07/13/17 / #20170198274

Human coagulation factor vii polypeptides

The present invention relates to novel human coagulation factor viia variants having coagulant activity as well as polynucleotide constructs encoding such variants, vectors and host cells comprising and expressing the polynucleotide, pharmaceutical compositions, uses and methods of treatment.. . ... Cordis Corporation

07/06/17 / #20170194670

Power tool and battery pack

A power tool includes a motor and control means for controlling the motor. The motor is capable of being driven by power supplied from a battery pack including a battery cell. ... Cordis Corporation

07/06/17 / #20170190775

Antibodies that bind and block triggering receptor expressed on myeloid cells-1 (trem-1)

The invention relates to antibodies that are capable of specifically binding trem-1 and preventing the activation of trem-1, a protein expressed on monocytes, macrophages and neutrophils. Such antibodies find utility in the treatment of individuals with an inflammatory disease, such as rheumatoid arthritis and inflammatory bowel disease.. ... Cordis Corporation

07/06/17 / #20170190757

Novel glucagon analogues

The present invention relates to novel peptide compounds which have a protracted profile of action and improved solubility and stability, to the use of the compounds in therapy, to methods of treatment comprising administration of the compounds to patients in need thereof, and to the use of the compounds in the manufacture of medicaments. The compounds of the invention are of particular interest in relation to the treatment of hyperglycemia, diabetes and obesity, as well as a variety of diseases or conditions associated with hyperglycemia, diabetes and obesity.. ... Cordis Corporation








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