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Cytokinetics Inc patents


Recent patent applications related to Cytokinetics Inc. Cytokinetics Inc is listed as an Agent/Assignee. Note: Cytokinetics Inc may have other listings under different names/spellings. We're not affiliated with Cytokinetics Inc, we're just tracking patents.

ARCHIVE: New 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 | Company Directory "C" | Cytokinetics Inc-related inventors


Tetrahydroisoquinoline derivatives

Novel tetrahydroisoquinoline derivative compounds are disclosed herein that may be used as an active ingredient for a pharmaceutical composition, and in particular, for a pharmaceutical composition useful for preventing or treating a disease or condition responsive to modulation of the contractility of the skeletal sarcomere. This may be accomplished, for example, by modulation of the troponin complex of the fast skeletal muscle sarcomere through one or more of fast skeletal myosin, actin, tropomyosin, troponin c, troponin i, and troponin t, and fragments and isoforms thereof. ... Cytokinetics Inc

Novel pharmaceutical composition for prevention and/or treatment of urinary incontinence

. . . . The problem to be solved by the present invention is to provide a novel pharmaceutical composition for prevention and/or treatment of urinary incontinence, which differs from conventional drugs. The present invention provides a therapeutic agent for prevention and/or treatment of urinary incontinence having 1-[2-({[trans-3-fluoro-1-(3-fluoropyridin-2-yl)cyclobutyl]methyl}amino)pyrimidin-5-yl]-1h-pyrrole-3-carboxamide or a salt thereof, as an active ingredient.. ... Cytokinetics Inc

Compounds, compositions and methods

Certain substituted urea derivatives selectively modulate the cardiac sarcomere, for example by potentiating cardiac myosin, and are useful in the treatment of systolic heart failure including congestive heart failure.. . ... Cytokinetics Inc

Methods for improving diaphragm function

Provided are compositions and methods for improving diaphragm function in a patient. In some embodiments, the methods comprise administering to a patient or contacting a diaphragm skeletal muscle fiber with an effective amount of a skeletal muscle troponin activator or pharmaceutically acceptable salt thereof. ... Cytokinetics Inc

Tetrahydroisoquinoline derivatives

Novel tetrahydroisoquinoline derivative compounds are disclosed herein that may be used as an active ingredient for a pharmaceutical composition, and in particular, for a pharmaceutical composition useful for preventing or treating a disease or condition responsive to modulation of the contractility of the skeletal sarcomere. This may be accomplished, for example, by modulation of the troponin complex of the fast skeletal muscle sarcomere through one or more of fast skeletal myosin, actin, tropomyosin, troponin c, troponin i, and troponin t, and fragments and isoforms thereof. ... Cytokinetics Inc

Methods of reducing decline in vital capacity

Provided herein are compositions and methods for reducing the decline in vital capacity in a subject by administering to the subject a skeletal muscle troponin activator. Also provided are compositions and methods for reducing respiratory decline in a subject, as measured by slow vital capacity (svc), by administering to the subject a skeletal muscle troponin activator.. ... Cytokinetics Inc








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