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Deutsches Krebsforschungszentrum patents (2017 archive)


Recent patent applications related to Deutsches Krebsforschungszentrum. Deutsches Krebsforschungszentrum is listed as an Agent/Assignee. Note: Deutsches Krebsforschungszentrum may have other listings under different names/spellings. We're not affiliated with Deutsches Krebsforschungszentrum, we're just tracking patents.

ARCHIVE: New 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 | Company Directory "D" | Deutsches Krebsforschungszentrum-related inventors


Binding molecules, especially antibodies, binding to l1cam (cd171)

The present disclosure relates to a binding molecule binding to l1, which is capable of binding to the same l1 epitope recognized by the monoclonal antibody l1-ov52.24, and/or which competes with the monoclonal antibody l1-ov52.24 for binding to l1, wherein the variable part of the light chain of l1-ov52.24 comprises the sequence according to seq id no: 1 or wherein the light chain is encoded by seq id no: 3, and wherein the variable part of the heavy chain of l1-ov52.24 comprises the sequence according to seq id no: 2 or wherein the heavy chain is encoded by seq id no: 4, nucleic acids encoding the binding molecules, uses thereof and pharmaceutical compositions comprising the binding molecules.. . ... Deutsches Krebsforschungszentrum

Method for the detection of antigen presentation

The present invention pertains to a method for detecting antigen presentation via antigen presenting molecules such as major histocompatibility complex (mhc) class i or ii. The invention deploys a first binding agent specific for the antigen epitope and a second binding agent specific for the antigen presenting molecule. ... Deutsches Krebsforschungszentrum

Hcbi, msbi, mssi and cmi sequences as an early marker for the future development of cancer and diseases of the cns and as a target for the treatment and prevention of these diseases

Described are hcbi (healthy cattle blood isolate), msbi (multiple sclerosis brain isolate), mssi (multiple sclerosis serum isolate) and cmi (cow milk isolate) nucleotide sequences as well as probes and primers comprising part of said nucleotide sequences and antibodies against polypeptides encoded by said nucleotide sequences. Said compounds are useful as early markers for the future development of cancer and diseases of the cns (multiple sclerosis ms, prion-linked diseases, amyotrophic lateral sclerosis, transmissible spongiforme encephalitis, parkinson's disease, alzheimer disease) and should represent targets for treatment and prevention.. ... Deutsches Krebsforschungszentrum

Receptors of rspo2 and rspo3

The present invention relates to the finding that syndecans (sdc) are receptors of rspondin-2 (rspo2) and rspondin-3 (rspo3). Thus, the present invention relates to the identification of rspo2, rspo3 and/or sdc activity modulators by determining if a test compound has the ability to modulate the binding of an rspo2 and/or rspo3 polypeptide to an sdc polypeptide. ... Deutsches Krebsforschungszentrum

Methods for the prediction of a personalized esa-dose in the treatment of anemia

The present invention pertains to the use of an integrative pharmacokinetic/pharmacodynamic (pk/pd) esa-epor mathematical model for calculating the binding behaviour of erythropoiesis stimulating agents (esa). The invention provides methods for the determining of esa binding sites in cells or patients suffering from anemia. ... Deutsches Krebsforschungszentrum

S100p and hyaluronic acid as biomarkers for metastatic breast cancer

The present invention pertains to a new method for the diagnosis, prognosis, stratification and/or monitoring of a therapy, of breast cancer in a patient. The method is based on the use of hyaluronic acid and s100p as combined biomarkers in the plasma of breast cancer patients. ... Deutsches Krebsforschungszentrum

Inhibitors of thioredoxin-interacting protein (txnip) for therapy

Described is a compound capable of reducing or inhibiting (a) the biological activity of thioredoxin-interacting protein (txnip) or (b) the expression of the gene encoding txnip for treating a condition where improving the resistance towards oxidative stress has a beneficial effect, e.g., for improving female fertiliy or extending healthy lifespan.. . ... Deutsches Krebsforschungszentrum








ARCHIVE: New 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009



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