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Edwards Lifesciences Corporation patents


Recent patent applications related to Edwards Lifesciences Corporation. Edwards Lifesciences Corporation is listed as an Agent/Assignee. Note: Edwards Lifesciences Corporation may have other listings under different names/spellings. We're not affiliated with Edwards Lifesciences Corporation, we're just tracking patents.

ARCHIVE: New 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 | Company Directory "E" | Edwards Lifesciences Corporation-related inventors


Bi-directional cannula

A bi-directional cannula for perfusing blood in two directions. The cannula has a distal opening in fluid communication with a cannula first lumen. ... Edwards Lifesciences Corporation

Systems for replacing a native heart valve and aorta with a prosthetic heart valve and conduit

A medical device includes an expandable conduit, a prosthetic heart valve and a delivery device, including a balloon catheter. The expandable conduit may include one or more inner or outer sleeves supported by a frame or stent. ... Edwards Lifesciences Corporation

Methods of implanting prosthetic heart valve using position markers

An exemplary two-stage prosthetic heart valve system has a radially expandable base stent implanted within a native valve annulus. The base stent desirably has three position markers projecting in the axial direction from the outflow end of the base stent to assist in aligning the stent with respect to the commissures of the native valve. ... Edwards Lifesciences Corporation

Percutaneous heart valve

A method of delivering a percutaneous heart valve is disclosed. The percutaneous heart valve includes an expandable frame having a plurality of cells and a valve seated inside the expandable frame. ... Edwards Lifesciences Corporation

Low profile transcatheter heart valve

A method of crimping an implantable prosthetic valve can include placing protective material over at least a portion of the implantable prosthetic valve. The protective material can be configured to occupy space between open cells of a frame of the implantable prosthetic valve to prevent damage to a leaflet structure of the implantable prosthetic valve. ... Edwards Lifesciences Corporation

Prosthetic valve for replacing mitral valve

A prosthetic apparatus for implantation in a native mitral valve includes a main body for placement within the native mitral annulus. The main body is compressible to a radially compressed state for delivery into the heart and is self-expandable from the compressed state to a radially expanded state for implantation. ... Edwards Lifesciences Corporation

Systems and mechanisms for deploying a docking device for a replacement heart valve

Systems and methods usable in delivering a docking device to a native valve of a patient's heart. A distal region of a delivery catheter can be positioned in an atrium of the heart and a distal tip can be positioned at or near a commissure of the native valve. ... Edwards Lifesciences Corporation

Heart valve manufacturing devices and methods

Methods for manufacturing or sewing a prosthetic heart valve and associated systems can include an assistance system that includes an automated fixture that can comprise an articulation arm and a target device holder. The automated fixture can be configured to rotate a target device held by the holder. ... Edwards Lifesciences Corporation

Heart valve docking devices and implanting methods

A system is in various embodiments configured to treat a native heart valve, such as to secure a prosthetic heart valve within a native valve. Embodiments of the system include a docking device with different coil portions, such as an upper coil and a lower coil, where the device is configured to assume an axially expanded state and an axially compressed state. ... Edwards Lifesciences Corporation

Humidity-management packaging systems and methods

Packaging systems and methods are disclosed for storing a bioprosthetic device comprising a bioprosthetic tissue and maintaining a target relative humidity across a temperature range. The packaging system includes a sealed package defining an internal space having an internal volume, and a humidity control device and bioprosthetic device within the internal space. ... Edwards Lifesciences Corporation

Method for replacing a heart valve

A method for replacing a native heart valve in need thereof comprises delivering to the native heart valve an apparatus comprising a valve member, a connecting member, and an anchor member suitable for anchoring the apparatus. The valve member reversibly moves between an open position and a closed position to augment or replace the function of the native valve leaflets, thereby reducing valve regurgitation. ... Edwards Lifesciences Corporation

Replacement heart valves, delivery devices and methods

A replacement heart valve and method of treating valve insufficiency includes an expandable frame configured to engage a native valve annulus. A valve body is coupled to the frame. ... Edwards Lifesciences Corporation

Replacement heart valves, delivery devices and methods

A replacement heart valve and method of treating valve insufficiency includes an expandable frame configured to engage a native valve annulus. A valve body is coupled to the frame. ... Edwards Lifesciences Corporation

Suturing devices for heart valve surgery

Disclosed are devices and methods for delivering several sutures accurately and simultaneously around the perimeter of an annular prosthetic device (prosthetic heart valve, annuloplasty ring, etc.) to secure the prosthetic device within a native heart valve region. Devices can comprise a proximal handle portion including an actuator and a distal suturing portion including several curved and straight needles arrayed around the shaft axis. ... Edwards Lifesciences Corporation

08/16/18 / #20180228607

Methods for delivering a prosthetic valve

Methods for delivering a prosthetic valve comprise introducing the prosthetic heart valve into a body of a patient. The prosthetic valve is mounted within a delivery sheath of a delivery apparatus in a radially compressed state. ... Edwards Lifesciences Corporation

08/16/18 / #20180228606

Methods of loading a prosthetic valve in a delivery apparatus

Embodiments of the present disclosure provide methods of loading a prosthetic heart valve within a delivery apparatus such that it can be used for delivery of the prosthetic heart valve to a native valve site via the human vasculature. The methods can include attaching the prosthetic heart valve to a valve-retaining mechanism at a distal end of the catheter and causing a torque shaft of the delivery apparatus to rotate relative to the catheter, wherein the torque shaft extends within the catheter and is coupled to the valve delivery sheath. ... Edwards Lifesciences Corporation

08/16/18 / #20180228605

Prosthetic heart valve packaging and deployment systems

Packaging for prosthetic heart valves including an assembly for securely retaining a heart valve within a jar and facilitating retrieval therefrom. The assembly includes a packaging sleeve that fits closely within the jar and has a clip structure for securing a valve holder. ... Edwards Lifesciences Corporation

08/16/18 / #20180228604

Steerable assembly for delivering a prosthetic heart valve

An assembly for delivering a prosthetic heart valve to a native heart valve is disclosed. The assembly includes a self-expanding prosthetic heart valve formed with an expandable metallic stent and a flexible valvular structure. ... Edwards Lifesciences Corporation

08/09/18 / #20180221150

Physiologically harmonized tricuspid annuloplasty ring

A prosthetic tricuspid remodeling annuloplasty ring having two free ends that are upturned in the inflow direction to help avoid unnecessary leaflet abrasion. The free ends are desirably separated across a gap that is large enough to reduce the risk of passing sutures through the conductive system of the heart, yet not too large that support of the septal leaflet of the tricuspid annulus is degraded. ... Edwards Lifesciences Corporation

08/09/18 / #20180221143

Prosthesis for atraumatically grasping intralumenal tissue and methods of delivery

A prosthesis can comprise an expandable frame, a plurality of distal anchors and a plurality of proximal anchors. The anchors can extend outwardly from the frame. ... Edwards Lifesciences Corporation

08/09/18 / #20180221016

Methods of securing a cardiac implant using knotless suture clamps

Suture locking clamps for securing prostheses such as heart valves or annuloplasty rings with sutures and without using knots improve the ease of implantation. The clamps have opposed clamp halves separated by a slot opening to one side and surrounded by a biasing member such as one or more c-clip springs. ... Edwards Lifesciences Corporation

08/09/18 / #20180221014

Transcatheter heart valve leaflet plication

An apparatus for repairing a heart valve can comprises a leaflet-plicating mechanism configured to plicate a leaflet of a heart valve and a helical needle comprising a plurality of coils. The needle can be configured to implant a suture to extend helically through plicated tissue of the heart valve. ... Edwards Lifesciences Corporation

08/02/18 / #20180214608

Methods for cross-linking bioprosthetic tissue using bio-orthogonal binding pairs

Methods for treating a bioprosthetic tissue are described. The methods comprise contacting the biological tissue with an anchor compound, the anchor compound comprising first and second functional groups. ... Edwards Lifesciences Corporation

08/02/18 / #20180214033

Hemodynamic monitor providing enhanced cardiac output measurements

A hemodynamic monitor implements an adaptive method that optimally estimates scaling and offset calibration parameters by using a computationally efficient, iterative online method to minimize the mean square error between a high bandwidth arterial pressure cardiac output (apco) measurement generated by a first physiological sensor affixed to a patient and a relatively low bandwidth continuous cardiac output (cco) measurement generated by a second physiological sensor also affixed to the patient. When calibration parameters are used to adjust an apco measurement, the combined apco/cco estimate provided by the hemodynamic monitor has accuracy comparable to a cco measurement, but also tracks cardiac output dynamical variations that are outside of the cco algorithm bandwidth.. ... Edwards Lifesciences Corporation

07/26/18 / #20180207411

Method of operating an integrated balloon catheter inflation system

An inflation system having two pressure vessels integrated into a balloon catheter. A pressurized chamber and a vacuum chamber are integrally attached to proximal end of the balloon catheter and activated by a common valve or switch. ... Edwards Lifesciences Corporation

07/26/18 / #20180207395

Expandable sheath

Disclosed herein are expandable introducer sheaths and methods of making and using the same. The sheaths minimize trauma to a patient's vasculature by allowing for temporary expansion of a portion of the sheath to accommodate passage of a delivery system for a cardiovascular device, then return to a non-expanded state after the passage of the device. ... Edwards Lifesciences Corporation

07/26/18 / #20180206992

Chordae tendineae adjustment

A method for improving leaflet prolapse and/or valve regurgitation associated with a heart valve involves introducing a chordae tendineae capturing device into a ventricle of a heart, the chordae tendineae capturing device comprising a central hub component and a plurality of spokes, extending the plurality of spokes outward from the central hub component, rotating the chordae tendineae capturing device in a first direction to bring at least one of the plurality of spokes into physical contact with one or more cords of chordae tendineae disposed in the ventricle, further rotating the chordae tendineae capturing device in the first direction to bring the one or more cords inward towards the central hub component, and closing the plurality of spokes at least partially over the one or more cords to secure the one or more cords.. . ... Edwards Lifesciences Corporation

07/26/18 / #20180206982

Covered prosthetic heart valve

A prosthetic heart valve includes a frame having a plurality of strut members, an inflow end, and an outflow end. The prosthetic heart valve further includes a leaflet structure situated at least partially within the frame, and a covering disposed around the frame. ... Edwards Lifesciences Corporation

07/26/18 / #20180206976

Surgical implant devices and methods for their manufacture and use

An implantable vascular device comprises an expandable and compressible implant body, a housing, a rotatable member, and a locking member. The housing is coupled to a first end portion of the implant body. ... Edwards Lifesciences Corporation

07/26/18 / #20180206969

Dry prosthetic heart valve packaging system

Packaging for prosthetic heart valves including an assembly for stabilizing dry prosthetic tissue implants such as heart valves during storage. The packaging assembly can be used for storing a bioprosthetic heart valve without a liquid preservative solution. ... Edwards Lifesciences Corporation

07/26/18 / #20180206838

Devices and methods for suturing a cardiac implant

Described herein are reusable surgical needles having a resiliently collapsible rear loop that captures a suture as it is passed through an object and resiliently expands upon exiting the object to release the suture. Also described are suture spool assemblies that comprise a rigid housing and a rotatable spool of suture material suspended within the housing so that a plurality of sutures can be dispensed from the assembly in succession during a surgery. ... Edwards Lifesciences Corporation

07/26/18 / #20180206789

Extremity cuff such as a finger cuff, a method and a computer program product

The invention relates to an extremity cuff such as a finger cuff for determining a physiological parameter. The extremity cuff comprises an extremity module for releasably surrounding an extremity portion in a circumferential direction. ... Edwards Lifesciences Corporation

07/19/18 / #20180200055

Prosthetic heart valve and delivery apparatus

Embodiments of the present disclosure provide a prosthetic heart valve usable with a heart valve delivery apparatus for delivery of the prosthetic heart valve to a native valve site via the human vasculature. In one embodiment, a self-expanding valve comprises an expandable stent that is shaped to maintain the valve in the aortic annulus against axial without anchors or retaining devices that engage the surrounding tissue. ... Edwards Lifesciences Corporation

07/19/18 / #20180200054

Prosthetic heart valve and method

A system for replacing a deficient native aortic valve includes an implantable prosthetic valve having a self-expandable frame and a valve assembly formed with three valve leaflets. The self-expandable frame includes three angularly spaced longitudinal bars of fixed length defining respective slots and a plurality of web-like constructions extending between and connected to the longitudinal bars. ... Edwards Lifesciences Corporation

07/19/18 / #20180200051

Actively controllable stent, stent graft, heart valve and method of controlling same

A delivery apparatus can include a handle portion and at least one rotatable drive shaft. The handle portion can have an actuation mechanism with a motor. ... Edwards Lifesciences Corporation

07/12/18 / #20180192962

Mean arterial pressure (map) derived prediction of future hypotension

There are provided systems and methods for performing mean arterial pressure (map) derived prediction of future hypotension. Such a system includes a hardware unit including a hardware processor and a system memory, a hypotension prediction software code stored in the system memory, and a sensory alarm. ... Edwards Lifesciences Corporation

07/05/18 / #20180185154

Heart valve coaptation device

In one embodiment, a leaflet capture device for improving the coaptation of heart valve leaflets is provided. The leaflet capture device can include a first clip portion having inner and outer portions. ... Edwards Lifesciences Corporation

07/05/18 / #20180185146

Prosthetic heart valve deployment systems

A quick-connect heart valve prosthesis that can be quickly and easily implanted is provided. The heart valve includes a substantially non-expandable, non-compressible prosthetic valve and a plastically-expandable coupling stent, thereby enabling attachment to the annulus without sutures. ... Edwards Lifesciences Corporation

06/28/18 / #20180177594

Heart valve docking devices and systems

Docking devices for docking a prosthetic valve at a native valve of a heart can include a coiled docking anchor and a retrieval suture. The docking device and retrieval suture can be configured for improved retention and retrieval of the docking device after deployment. ... Edwards Lifesciences Corporation

06/28/18 / #20180177592

Low-profile heart valve and delivery system

Disclosed replacement heart valves can be designed to be delivered to a native valve site while crimped on a delivery catheter. The crimped profile of the replacement valve can be minimized by, for example, separating a frame or stent structure from a leaflet structure, along the axial direction. ... Edwards Lifesciences Corporation

06/28/18 / #20180177591

Inverted leaflet prosthetic valve

Prosthetic valve embodiments are described herein that include a frame and a valve member mounted within the frame. The valve members can have a plurality of leaflets that are affixed to one another along their inflow edges, with articulating edges projecting from the inflow edges in the outflow direction. ... Edwards Lifesciences Corporation

06/28/18 / #20180177503

Suture fastener having spaced-apart layers

In one embodiment, a multi-layer suture fastener that includes a generally disc-shaped body defining a plurality of axially spaced-apart layers. Each layer can include an inner axial surface and an outer axial surface. ... Edwards Lifesciences Corporation

06/21/18 / #20180168809

Covered heart valve sizer

A heart valve sizer and sizer cover are provided for determining the size of a heart valve annulus. The valve sizer can include a handle, a shaft extending distally from the handle, a sizing element coupled to the distal end of the shaft, the sizing element being movable between a first retracted position and a second expanded position, and a sizer cover. ... Edwards Lifesciences Corporation

06/21/18 / #20180168804

Docking device made with 3d woven fabric

A docking device for a bioprosthesis is disclosed that can change shape and recover after a deforming stress is removed, that adjusts to surrounding conditions to accommodate different complex anatomic geometries, and that mitigates leakage around the bioprosthesis. The docking device can include a 3d woven fabric forming an internal surface, an outer surface, and a thickness therebetween. ... Edwards Lifesciences Corporation

06/07/18 / #20180153689

Mechanically expanding heart valve and delivery apparatus therefor

An assembly can comprise a radially expandable and compressible annular frame, at least one linear actuator assembly coupled to the frame and at least one locking mechanism coupled to the frame. The linear actuator can be configured to apply a distally directed force and/or a proximally directed force to the frame to radially expand or compress the frame. ... Edwards Lifesciences Corporation

06/07/18 / #20180153415

Aortic stenosis classification

According to one implementation, a medical device includes a display, a blood pressure sensor for sensing an arterial blood pressure of a patient and for generating a blood pressure signal, an analog-to-digital converter (adc) for receiving the blood pressure signal and for converting the blood pressure signal to blood pressure data in digital form, and a hardware processor for executing an aortic stenosis diagnostic software code. The hardware processor executes the aortic stenosis diagnostic software code to receive the blood pressure data from the adc, and to identify parameters indicative of aortic stenosis in the patient, based on the blood pressure data. ... Edwards Lifesciences Corporation

05/31/18 / #20180147616

Methods for stent shaping

An apparatus for crimping a radially expandable stent includes a pressure vessel, shaping balloon, and mandrel. The mandrel is configured to slidingly receive a stent thereon, and to be slidingly advanced into the pressure vessel. ... Edwards Lifesciences Corporation

05/31/18 / #20180147323

Pre-stressing and capping bioprosthetic tissue

A treatment for bioprosthetic tissue used in implants or for assembled bioprosthetic heart valves to reduce in vivo calcification is disclosed. The method includes preconditioning, pre-stressing, or pre-damaging fixed bioprosthetic tissue in a manner that mimics the damage associated with post-implant use, while, and/or subsequently applying a calcification mitigant such as a capping agent or a linking agent to the damaged tissue. ... Edwards Lifesciences Corporation

05/31/18 / #20180147060

Methods of conformal expansion of prosthetic heart valves

A system for expanding a device in a conduit or orifice of a human body includes a balloon member that is movable from a first configuration to a second configuration. External surfaces of the balloon member can collectively have a non-cylindrical cross-section relative to a main axis of the balloon member, such that the external surfaces of the balloon member generally conform to the anatomical shape of the conduit or orifice when the balloon member is in the second configuration.. ... Edwards Lifesciences Corporation

05/31/18 / #20180147054

Percutaneous leaflet augmentation

In a representative embodiment, an implantable prosthetic heart valve device comprises an elongated body having first and second end portions, the body being configured to be implanted around a native leaflet of a heart valve such that the first end portion is on an atrial side of the leaflet and the second end portion is on a ventricular side of the leaflet and such that the body can coapt with and move away from an opposing native leaflet during operation of the heart valve. The device can further comprises a fastener configured to be mounted on a suture that extends from one of the first or second end portions, through the native leaflet and through the other of the first or second end portions such that the body is secured to the native leaflet.. ... Edwards Lifesciences Corporation

05/17/18 / #20180133003

Prosthetic heart valve having leaflet inflow below frame

Embodiments of a prosthetic heart valve are disclosed. An implantable prosthetic valve can include an annular frame having an inflow end, an outflow end and a central longitudinal axis extending from the inflow end to the outflow end. ... Edwards Lifesciences Corporation

05/17/18 / #20180133000

Crimping accessory device for a prosthetic valve

Embodiments are provided of an assembly having a prosthetic valve, the prosthetic valve having a radially expandable and compressible annular frame, and a crimping accessory device, and methods for using the assembly in compressing the prosthetic valve. The frame includes an outer surface and an inner surface. ... Edwards Lifesciences Corporation

05/10/18 / #20180126124

Apparatus for the introduction and manipulation of multiple telescoping catheters

A delivery apparatus includes a steerable shaft having a proximal portion, a distal portion, and a pull-wire conduit that extends through the proximal and distal portions. A pull wire extends through the conduit and has a distal portion that is fixed to the shaft. ... Edwards Lifesciences Corporation

05/10/18 / #20180125656

Prosthetic heart valve delivery apparatus

Certain embodiments of the present disclosure provide a prosthetic valve (e.g., prosthetic heart valve) and a valve delivery apparatus for delivery of the prosthetic valve to a native valve site via the human vasculature. The delivery apparatus is particularly suited for advancing a prosthetic heart valve through the aorta (i.e., in a retrograde approach) for replacing a diseased native aortic valve. ... Edwards Lifesciences Corporation

05/10/18 / #20180125653

Mitral heart valve storage and handling system

An improved holder and storage system for a tissue-type prosthetic mitral heart valve that constricts the commissure posts of the valve and prevents suture looping. A rod axially movable relative to the holder tensions lengths of attachment sutures that extend between the commissure post tips to create a tent and flex the tips inward, thus helping to prevent looping of any of an array of pre-implanted sutures around the leading tips during delivery of the valve. ... Edwards Lifesciences Corporation

05/10/18 / #20180125645

Mitral valve prosthesis with atrial anchoring

A method of treating a mitral valve without open-heart surgery is disclosed. An expandable prosthesis comprises an anchoring portion and an occluding member coupled to the anchoring portion. ... Edwards Lifesciences Corporation

05/10/18 / #20180125644

Methods of delivery of heart valves

A prosthetic heart valve can include a valve frame having a wireform portion and a stent portion. The wireform and stent portions can be undetachably coupled together via a plurality of upright struts so as to form a one-piece prosthetic heart valve frame. ... Edwards Lifesciences Corporation

05/10/18 / #20180125643

Heart valve delivery system with valve catheter

An assembly for treating a native valve in a human heart includes a prosthetic heart valve having an expandable frame and a valvular structure. The assembly also includes a tubular sleeve and a valve catheter disposed within the sleeve. ... Edwards Lifesciences Corporation

05/03/18 / #20180116795

Prosthetic mitral valve holders

Valve holders and introducers for delivering a prosthetic heart valve to an implant site are in various embodiments configured to facilitate insertion of prosthetic valves through small incisions or access sites on a patient's body. The valve holders can also be configured to reduce or eliminate the occurrence of suture looping or other damage to the prosthetic valve during implantation. ... Edwards Lifesciences Corporation

05/03/18 / #20180116790

Supra and sub-annular mitral valve delivery system

Methods are described herein for delivering a replacement mitral valve to a native mitral valve location. In one method, ventricular anchors of the replacement mitral valve are released and allowed to reverse orientation while positioned in the left atrium of a human heart. ... Edwards Lifesciences Corporation

04/19/18 / #20180104077

Actively controllable stent, stent graft, heart valve and method of controlling same

A delivery apparatus comprises a handle portion and at least one rotatable drive shaft. The handle portion has an actuation mechanism and a display. ... Edwards Lifesciences Corporation

04/19/18 / #20180104058

Sizing methods for a valved conduit graft

A sizing tool for use in implanting a composite valved conduit having a prosthetic heart valve on a distal end attached to a conduit graft that extends to a proximal end. The tool includes a proximal handle and a distal shaft, a prosthetic heart valve sizer having an axis affixed to a distal end of the shaft, and a conduit graft replica having an axis mounted on the shaft proximal to the heart valve sizer. ... Edwards Lifesciences Corporation

04/19/18 / #20180104049

Methods and apparatuses for deploying minimally-invasive heart valves

An assembly includes an expandable prosthetic heart valve, a catheter shaft, and a stabilization device. The expandable prosthetic heart valve has a valve body and a plurality of leaflets coupled to the valve body. ... Edwards Lifesciences Corporation

04/05/18 / #20180092741

Prosthetic heart valve with cusp positioners

A prosthetic heart valve has three cusp regions positioned at an inflow end intermediate three commissure regions positioned at an outflow end thereof. A support frame including three cusp positioners is fixed with respect to a leaflet frame and located intermediate each pair of adjacent commissure regions. ... Edwards Lifesciences Corporation

03/22/18 / #20180078394

Device and method for increasing flow through the left atrial appendage

Methods and devices for increasing flow in the left atrial appendage (laa) include a conduit directing blood flow from a pulmonary artery into the laa and/or a conduit drawing blood from the laa by a bernoulli effect. In one embodiment, a method comprises implanting a conduit in a pulmonary vein, expanding an inlet portion such that the conduit becomes anchored within the vein and directs blood through an outlet portion of the conduit into or toward the left atrial appendage.. ... Edwards Lifesciences Corporation

03/22/18 / #20180078367

Prosthetic heart valve with reduced stitching

An implantable prosthetic valve that is radially collapsible to a collapsed configuration and radially expandable to an expanded configuration includes an annular frame including a plurality of angled strut members, and a skirt member secured to the frame. The skirt member includes a plurality of extension portions wrapped around at least one strut member adjacent the extension portions. ... Edwards Lifesciences Corporation

03/22/18 / #20180078362

Device and method for improving heart valve function

The invention is a method for reducing regurgitation through a mitral valve. The device and method is directed to an anchor portion for engagement with the heart wall and an expandable valve portion configured for deployment between the mitral valve leaflets. ... Edwards Lifesciences Corporation

03/15/18 / #20180071500

Methods of fabricating a transcatheter device having an inflatable balloon

Inflatable devices are disclosed including a surface which has a network of polymer chains and is configured to be inflatable into a therapeutically or diagnostically useful shape, and at least one ultrashort laser pulse-formed modification in the surface. The network can, for example, include a network morphology that is substantially unchanged by modification with the ultrashort pulse laser. ... Edwards Lifesciences Corporation

03/15/18 / #20180071490

Multi-direction steerable handles for steering catheters

Disclosed herein are steerable catheter assemblies and methods of steering catheters that utilize gimbal plate and ring mechanisms to accomplish independent control of catheter flex magnitude and catheter flex direction. Some embodiments include a catheter with two or more pull wires that flex the catheter, a housing connected to the catheter, a gimbal ring pivotally connected to the housing, a gimbal plate pivotally connected to the gimbal ring to form a gimbal assembly, and an adjustment member coupled to the gimbal assembly, such that the adjustment member is movable axially and rotationally relative to the gimbal assembly. ... Edwards Lifesciences Corporation

03/15/18 / #20180071489

Multi-direction steerable handles for steering catheters

Disclosed herein are steerable catheter assemblies and methods of steering catheters that utilize ball and socket mechanisms to accomplish independent control of catheter flex magnitude and catheter flex direction. Some embodiments include a catheter with two or more pull wires that flex the catheter, a first ball, a socket coupled to the first ball to form a ball and socket assembly, and an adjustment member coupled to the ball and socket assembly, such that the adjustment member is movable axially and rotationally relative to the ball and socket assembly. ... Edwards Lifesciences Corporation

03/15/18 / #20180071488

Multi-direction steerable handles for steering catheters

Steerable catheters include cam and follower mechanisms that provide independent control of catheter flex magnitude and catheter flex direction to provide improved steerability of an attached catheter. In certain embodiments, the steerable catheter assemblies include two or more pull wires that flex the catheter, and a control handle coupled to the catheter having a direction control and a magnitude control, both of which are operably coupled to the two or more pull wires by the cam and follower mechanism. ... Edwards Lifesciences Corporation

03/15/18 / #20180071487

Multi-direction steerable handles for steering catheters

Disclosed herein are steerable catheter assemblies that utilize various mechanisms to accomplish independent control of catheter flex magnitude and catheter flex direction to provide improved steerability of an attached catheter. Some embodiments include a catheter with two or more pull wires that flex the catheter and a control handle coupled to the catheter. ... Edwards Lifesciences Corporation

03/15/18 / #20180071085

Heart valve pinch devices and delivery systems

Pinch devices and access systems that can be used to secure a prosthetic heart valve to a heart valve annulus and to treat valvular insufficiency. A pinch device can be a separate expandable element from the prosthetic heart valve that is first advanced to the annulus and deployed, after which an expandable prosthetic heart valve can be advanced to within the annulus and deployed. ... Edwards Lifesciences Corporation

03/01/18 / #20180055634

Repositionable endoluminal support structure and its applications

A prosthetic heart valve includes a frame, a valve component, and a skirt. The frame has first and second end portions, a central longitudinal axis extending between the first and second end portions, and a plurality of struts interconnected by a plurality of joints. ... Edwards Lifesciences Corporation

03/01/18 / #20180055630

Heart valve docking system

Docking devices can be configured to be positioned at a native valve of a human heart to provide structural support for docking a prosthetic valve. The docking devices generally have coiled structures that define an inner space in which the prosthetic valve can be held. ... Edwards Lifesciences Corporation

03/01/18 / #20180055629

Multi-portion replacement heart valve prosthesis

A replacement mitral valve prosthesis includes a support structure and a valve body having three flexible leaflets. The support structure preferably includes an internal valve frame and an external sealing frame. ... Edwards Lifesciences Corporation

03/01/18 / #20180055628

Heart valve docking coils and systems

Anchoring or docking devices configured to be positioned at a native valve of a human heart and to provide structural support for docking a prosthetic valve therein. The docking devices can have coiled structures that define an inner space in which the prosthetic valve can be held. ... Edwards Lifesciences Corporation

03/01/18 / #20180055509

Suture clips, deployment devices therefor, and methods of use

A device for deploying a suture clip onto a suture can include a proximal handle portion that includes an actuation mechanism. The device can also include an outer shaft defining an inner lumen. ... Edwards Lifesciences Corporation

03/01/18 / #20180055505

Tissue retractor

A surgical site retractor is configured to retract tissue, such as in an intercostal procedure. The retractor may be formed from non-radiopaque material for improved monitoring via x-ray imaging. ... Edwards Lifesciences Corporation

02/22/18 / #20180049876

Annulus rings with suture clips

Disclosed herein are annular prosthetic devices, such as annuloplasty rings, that include suture clips integrated into or mounted within an annular frame. The clips can quickly secure to sutures to obviate the need to tied knots in the sutures during implantation. ... Edwards Lifesciences Corporation

02/22/18 / #20180049873

Steerable delivery system for replacement mitral valve and methods of use

Devices, systems and methods are described herein to provide improved steerability for delivering a prosthesis to a body location, for example, for delivering a replacement mitral valve to a native mitral valve location. The delivery system can include a number of advantageous steering and delivery features, in particular for the transseptal delivery approach.. ... Edwards Lifesciences Corporation

02/15/18 / #20180042744

Sealable endovascular implants and methods for their use

A prosthetic implant includes a circumferentially adjustable sealing collar and a rotatable sealer gear. The sealing collar has a central longitudinal axis. ... Edwards Lifesciences Corporation

02/15/18 / #20180042722

Collapsible cardiac implant and deployment system

A collapsible device, such as an annuloplasty ring or prosthetic heart valve, is configured to be collapsed prior to being introduced into a patient via minimally-invasive access points such as port holes or intercostal incisions. A holder is configured to hold the collapsible device, and to selectively collapse the device for introduction into the patient and then re-enlarge the device at the desired deployment site. ... Edwards Lifesciences Corporation

02/15/18 / #20180042690

Bioprosthetic heart valves having adaptive seals to minimize paravalvular leakage

A packaged bioprosthetic heart valve comprising a bioprosthetic heart valve, an adaptive seal and a package. The bioprosthetic heart valve comprises an at least partially dehydrated biological tissue leaflet structure coupled to a supporting frame. ... Edwards Lifesciences Corporation

02/08/18 / #20180036126

Devices for remodeling a valve annulus and ventricle

Devices and related methods of use are provided for improving heart function. In one embodiment of the present disclosure, a device includes a ring-like structure configured to be secured to a heart valve; at least one elongate member extending from the ring-like structure, wherein an end of the elongate member is configured to be secured to heart geometry other than a heart valve; and an adjustment mechanism for simultaneously altering a dimension of the ring-like structure and a length of the elongate member.. ... Edwards Lifesciences Corporation

02/08/18 / #20180036124

Delivery systems for prosthetic heart valve

A delivery apparatus for a prosthetic heart valve includes a shaft, an inner balloon, and an outer balloon. The shaft has a lumen extending from a proximal end portion to a distal end portion and a plurality of openings formed in the distal end portion. ... Edwards Lifesciences Corporation

02/01/18 / #20180028313

Retaining mechanisms for prosthetic valves

Prosthetic valve systems for replacing a native valve exhibiting regurgitation comprises a support structure and a transcatheter heart valve (thv) that is separate from the support structure. The support structure can be configured to be positioned such that it extends annularly around the native valve leaflets. ... Edwards Lifesciences Corporation

02/01/18 / #20180028310

Prosthetic heart valve

A prosthetic heart valve can include a radially collapsible and expandable annular frame having a plurality of struts defining openings. The prosthetic heart valve can further include a plurality of leaflets that regulate the flow of blood through the frame. ... Edwards Lifesciences Corporation

02/01/18 / #20180028309

Retaining mechanisms for prosthetic valves

Disclosed herein are representative embodiments of methods, apparatus, and systems used to deliver a prosthetic heart valve to a deficient valve. In one embodiment, for instance, a support member is positioned to at least partially surround the native leaflets of a valve. ... Edwards Lifesciences Corporation

02/01/18 / #20180028076

Health monitoring unit with hypotension predictive graphical user interface (gui)

A health monitoring unit includes a hardware processor, a memory, a display, and a graphical user interface (gui) stored in the memory. The gui is executed by the processor to provide a selection screen enabling a user to select parameters for viewing on the display from among health parameters of a living subject being tracked by the health monitoring unit. ... Edwards Lifesciences Corporation

01/25/18 / #20180025290

Predictive risk model optimization

A system disclosed herein includes a hardware processor and a predictive risk model training software code stored in a system memory. The hardware processor executes the software code to receive vital sign data of a population of subjects including positive and negative subjects with respect to a health state, to define data sets for use in training a predictive risk model, to transform the vital sign data to parameters characterizing the vital sign data, and to obtain differential parameters based on those parameters. ... Edwards Lifesciences Corporation

01/25/18 / #20180021135

Adjustable annuloplasty ring replica sizer

A dynamic, adjustable annuloplasty ring sizer can include an adjustable ring replica, which can be adjusted through a range of sizes corresponding to available prosthetic annuloplasty repair ring sizes. Actuation of an adjustment trigger on a handle portion of the ring sizer can displace tension wires that extend through a malleable shaft and through a plurality of articulating segments that form the ring replica. ... Edwards Lifesciences Corporation

01/25/18 / #20180021129

Replacement heart valve prosthesis

A prosthesis can be configured to grasp intralumenal tissue when deployed within a body cavity and prevent axial flow of fluid around an exterior of the prosthesis. The prosthesis can include an expandable frame configured to radially expand and contract for deployment within the body cavity and a valve body. ... Edwards Lifesciences Corporation

01/25/18 / #20180021127

Prosthetic heart valve having improved commissure supports

A prosthetic heart valve can comprise a radially collapsible and expandable annular frame and a leaflet structure comprising a plurality of leaflets mounted within the frame. The frame can have commissure attachment portions that are configured to support the commissures of the leaflets in unique ways. ... Edwards Lifesciences Corporation

01/25/18 / #20180020989

Mean arterial pressure (map) derived prediction of future hypotension

There are provided systems and methods for performing mean arterial pressure (map) derived prediction of future hypotension. Such a system includes a hardware unit including a hardware processor and a system memory, a hypotension prediction software code stored in the system memory, and a sensory alarm. ... Edwards Lifesciences Corporation

01/11/18 / #20180008407

Expandable sheath and methods of using the same

The expandable sheath and methods of use disclosed herein are used to deliver a prosthetic device through a patient's vasculature. The sheath is constructed to be expandable in the circumferential direction, while maintaining sufficient stiffness in the longitudinal direction to withstand pushing and resist kinking the sheath includes a plurality of curved arms extending outwardly from a longitudinally extending spine. ... Edwards Lifesciences Corporation

01/11/18 / #20180008404

Docking station for heart valve prosthesis

An anchoring device that can be positioned within a native valve, such as the native mitral valve, to secure a replacement prosthetic valve in place. The anchoring device can comprise a docking station formed of a super elastic wire-like member defining a continuous, closed shape. ... Edwards Lifesciences Corporation

01/11/18 / #20180008403

Device and method for treating vascular insufficiency

Embodiments of a leaflet clip device and method of reducing regurgitation through a native heart valve are disclosed. A leaflet clip device can include an elongated clipping member having a first end portion and a second end portion and a tensioning mechanism coupled to the clipping member. ... Edwards Lifesciences Corporation

01/11/18 / #20180008249

Bio-absorbable wound closure device and method

A wound closure device comprises a first frame and a flexible tubular section connected to the first frame, the first frame implantable through a wound in a patient's skin into a lumen of a blood vessel with a portion of the tubular section extending out through the skin. The tubular section has a first portion and a second portion, a wall of the tubular section defining a coaxial inner bore. ... Edwards Lifesciences Corporation

01/11/18 / #20180008205

Predictive weighting of hypotension profiling parameters

A system having a processor obtain a digital hemodynamic data from a hemodynamic sensor, obtain one or more vital sign parameters characterizing vital sign data from the digital hemodynamic data, derive differential parameters based on the one or more vital sign parameters, generate combinatorial parameters using the one or more vital sign parameters and the differential parameters, determine a risk score corresponding to a probability of a future hypotension event for the living subject based on a weighted combination of a plurality of hypotension profiling parameters including the one or more vital sign parameters characterizing vital sign data, the differential parameters and the combinatorial parameters, and invoke a sensory alarm if the risk score satisfies a predetermined risk criterion.. . ... Edwards Lifesciences Corporation

01/04/18 / #20180000585

Method for replacing a heart valve

A method for replacing a native heart valve in need thereof comprises delivering to the native heart valve an apparatus comprising a valve member, a connecting member, and an anchor member suitable for anchoring the apparatus. The valve member reversibly moves between an open position and a closed position to augment or replace the function of the native valve leaflets, thereby reducing valve regurgitation. ... Edwards Lifesciences Corporation

12/28/17 / #20170367858

Compact crimping device

A compact crimping mechanism well-suited for use with devices such as stented prosthetic heart valves. The crimping mechanism includes a plurality of jaws configured for coordinated inward movement toward a crimping axis to reduce the size of a crimping iris around a stented valve. ... Edwards Lifesciences Corporation

12/28/17 / #20170367821

System and method for crimping a prosthetic valve

Embodiments of a crimping device for crimping a radially expandable and compressible prosthetic valve are disclosed. A crimping device can comprise a housing configured to receive a prosthetic valve in a radially expanded state. ... Edwards Lifesciences Corporation

12/21/17 / #20170360585

Systems and methods for manufacturing a stent frame

A prosthetic heart valve can include a support structure, an actuator member, and a plurality of leaflets. The support structure can have a plurality of struts and a plurality of rivets. ... Edwards Lifesciences Corporation

12/21/17 / #20170360560

Integrated heart valve delivery system

An assembly includes a prosthetic heart valve and a delivery apparatus for implanting the prosthetic heart valve within the native aortic valve of a patient. The prosthetic heart valve has a radially compressible and expandable metallic stent and a flexible valvular structure mounted within the stent. ... Edwards Lifesciences Corporation

12/14/17 / #20170354497

Replacement heart valve

A replacement heart valve can have an expandable frame configured to engage a native valve annulus. A valve body can be mounted onto the expandable frame to provide functionality similar to a natural valve. ... Edwards Lifesciences Corporation

12/14/17 / #20170354496

Replacement heart valve

A replacement heart valve can have an expandable frame configured to engage a native valve annulus. A valve body can be mounted onto the expandable frame to provide functionality similar to a natural valve. ... Edwards Lifesciences Corporation

12/07/17 / #20170348098

Method of replacing mitral valve

A method of implanting a prosthetic mitral heart valve includes advancing a guidewire through a femoral vein, an atrial septum, and a native mitral valve. A guide catheter is advanced over the guidewire and a delivery catheter is advanced through the guide catheter. ... Edwards Lifesciences Corporation

12/07/17 / #20170348097

Crimping device

A crimping system for a prosthetic heart valve comprises an elongate rigid body and a radially flexible, tubular sock. The body has an inner lumen extending along a central longitudinal axis between an insertion end and an outlet end. ... Edwards Lifesciences Corporation

11/30/17 / #20170340443

Posterior mitral valve leaflet approximation

The present disclosure provides embodiments of a method for improving coaptation of the anterior and posterior mitral valve leaflets by applying a remodeling force to the posterior leaflet. In particular embodiments, a tension member is secured at a location on or proximate to the posterior leaflet. ... Edwards Lifesciences Corporation

11/30/17 / #20170340441

Implantable prosthetic valve with non-laminar flow

A prosthetic heart valve can include an expandable support stent, a valve assembly, and a connecting membrane. The support stent can have first and second end portions and can be configured to be radially expandable from a first configuration to a second configuration. ... Edwards Lifesciences Corporation

11/30/17 / #20170340440

Prosthesis for atraumatically grasping intralumenal tissue and methods of delivery

A prosthesis can comprise an expandable frame, a plurality of distal anchors and a plurality of proximal anchors. The anchors can extend outwardly from the frame. ... Edwards Lifesciences Corporation

11/23/17 / #20170333188

Prosthetic mitral valve

A prosthetic mitral valve with a compressible and expandable stent that, when expanded, is circumferentially oval, elliptical, or d-shaped, with a major axis and a minor axis ratio of from about 3:4 to about 4:5. Embodiments of the stent comprise three commissure regions disposed towards an outflow end and three curved cusp regions between adjacent commissure regions. ... Edwards Lifesciences Corporation

11/23/17 / #20170333182

Prosthetic heart valve with cusp positioners

A prosthetic heart valve has three cusp regions positioned at an inflow end intermediate three commissure regions positioned at an outflow end thereof. A support frame including three cusp positioners is fixed with respect to a leaflet frame and located intermediate each pair of adjacent commissure regions. ... Edwards Lifesciences Corporation

11/16/17 / #20170325976

System and method for applying material to a stent

Methods for applying polymeric material to a stent are disclosed. A mandrel is coupled to a stent body. ... Edwards Lifesciences Corporation

11/09/17 / #20170319341

Systems of heart valve delivery on a beating heart

A delivery system and method for delivering a prosthetic heart valve to the aortic valve. The system includes a delivery catheter having a steering mechanism thereon for delivering a balloon-expandable prosthetic heart valve to the aortic valve through an introducer passing into the left ventricle through its apex. ... Edwards Lifesciences Corporation

10/26/17 / #20170304050

Beating-heart mitral valve chordae replacement

Methods and devices for the treatment of cardiac valve dysfunction through the placement of lines and anchors. The lines and anchors can form artificial chordae between valve leaflets and the ventricular wall or papillary muscles or connect the two valve leaflets together. ... Edwards Lifesciences Corporation

10/05/17 / #20170281346

Methods of implanting a cardiac implant with integrated suture fasteners

A cardiac implant system including a cardiac implant such as an annuloplasty ring, a prosthetic heart valve, or a valved conduit pre-assembled at the time of manufacture with devices for securing the implant to a heart valve annulus using knotless suture fasteners. The knotless suture fasteners may be embedded within a pliant sealing edge of the cardiac implant, or they may be positioned adjacent to the sealing edge. ... Edwards Lifesciences Corporation

10/05/17 / #20170281345

Method for treating an aortic valve

A method of implanting a prosthetic heart valve includes advancing the prosthetic heart valve in a radially-contracted configuration into an annulus of a native aortic valve. The prosthetic heart valve includes a self-expanding body and a plurality of leaflets fastened to the body. ... Edwards Lifesciences Corporation

10/05/17 / #20170281342

Surgical heart valves adapted for post-implant expansion

A prosthetic heart valve configured to replace a native heart valve and having a support frame configured to be reshaped into an expanded form in order to receive and/or support an expandable prosthetic heart valve therein is disclosed, together with methods of using same. The prosthetic heart valve may be configured to have a generally rigid and/or expansion-resistant configuration when initially implanted to replace a native valve (or other prosthetic heart valve), but to assume a generally expanded form when subjected to an outward force such as that provided by a dilation balloon or other mechanical expander.. ... Edwards Lifesciences Corporation

10/05/17 / #20170281340

Expandable surgical heart valve indicators

A prosthetic heart valve configured to replace a native heart valve and for post-implant expansion and having a valve-type indicator thereon visible from outside the body post-implant. The indicator communicates information about the valve, such as the size or orifice diameter of the valve, and/or that the valve has the capacity for post-implant expansion. ... Edwards Lifesciences Corporation

10/05/17 / #20170281337

Spacer for securing a transcatheter valve to a bioprosthetic cardiac structure

A spacer for creating a docking station for a transcatheter heart valve is provided. The spacer changes an effective diameter and/or a shape of an implanted bioprosthetic structure such as a bioprosthetic heart valve or annuloplasty ring, providing a supporting structure into which the transcatheter valve expands without over expanding. ... Edwards Lifesciences Corporation

09/28/17 / #20170273787

Delivery system for prosthetic heart valve

A delivery apparatus for implanting a prosthetic implant in a native lumen of the body includes a handle portion, and a first shaft extending from and movable relative to the handle portion. The first shaft has a proximal end portion coupled to the handle portion and a distal end portion. ... Edwards Lifesciences Corporation

09/21/17 / #20170266413

Cam controlled multi-direction steerable handles

Disclosed herein are catheter control handles that include various cam-based mechanisms for controlling the circumferential angle and radial magnitude of flexion of an attached catheter. Control handles can comprise a housing defining a longitudinal axis extending in distal and proximal directions, a cam member that is movable axially relative to the housing and also movable rotationally about the longitudinal axis relative to the housing, at least one follower engaged with the cam member such that the at least one follower moves relative to the handle in response to the movement of the cam member, and pull wires that are coupled to the at least one follower and that extend distally out of the handle and into a steerable catheter. ... Edwards Lifesciences Corporation

09/21/17 / #20170266004

Multi-stranded heat set annuloplasty rings

An annuloplasty repair segment for heart valve annulus repair. In one embodiment a multi-stranded cable replaces solid core wire for both the tricuspid and mitral valves. ... Edwards Lifesciences Corporation

09/21/17 / #20170265757

Integrated pressure sensing device

An integrated pressure sensing device is disclosed. Embodiments of the disclosed concepts provide a device that integrates hemodynamic pressure transducers or sensors into a single package. ... Edwards Lifesciences Corporation

09/21/17 / #20170265756

Thermodilution injectate measurement and control

Apparatus and methods for the measurement, control, or both, of thermodilution injectate flow for calculation of transpulmonary thermodilution parameters. An injectate delivery system includes a syringe for holding an injectate and a conduit configured at one end to be connected to a catheter. ... Edwards Lifesciences Corporation

09/14/17 / #20170258585

Valve implant with integrated sensor and transmitter

Sensor-integrated prosthetic valves that can comprise a variety of features, including a plurality of valve leaflets, a frame assembly configured to support the plurality of valve leaflets and define a plurality of commissure supports terminating at an outflow end of the prosthetic valve, a sensor device associated with the frame assembly and configured to generate a sensor signal, for example, a sensor signal indicating deflection of one or more of the plurality of commissure supports, and a transmitter assembly configured to receive the sensor signal from the sensor device and wirelessly transmit a transmission signal that is based at least in part on the sensor signal.. . ... Edwards Lifesciences Corporation

09/14/17 / #20170258584

Delivery cylinder for prosthetic implant

A delivery cylinder for a prosthetic implant can include a first tubular portion and a second tubular portion. The second tubular portion has a plurality of strut members coupled to the first tubular portion that define a volume for containing the prosthetic implant in a radially compressed state. ... Edwards Lifesciences Corporation

09/07/17 / #20170252157

Low profile transcatheter heart valve

A method of crimping an implantable prosthetic valve can include placing protective material over at least a portion of the implantable prosthetic valve. The protective material can be configured to occupy space between open cells of a frame of the implantable prosthetic valve to prevent damage to a leaflet structure of the implantable prosthetic valve. ... Edwards Lifesciences Corporation

09/07/17 / #20170252040

Self-cinching surgical clips and delivery system

A device and method for deploying self-cinching surgical clips. The device accesses at least two layers of tissue or material from only one side of the tissue or material and punctures through the two layers of tissue or material. ... Edwards Lifesciences Corporation

09/07/17 / #20170252035

Systems and method for deploying surgical suture

A device for suturing an incision in an artery has a handle, a supply of suture stored on spindle housed in the handle, a tube extending from the handle having a lumen through which suture extends, and a curved needle at a distal end of the handle, the curved needle having an opening through which a free end of the suture extends. A method for suturing an incision in an artery includes creating sequential openings in first and second flaps of the incision, with loops of suture extending through openings in one flap, with a free end of suture extending through the second flap being pulled through the loops and secured to another free end of suture extending through the first flap, to close the incision.. ... Edwards Lifesciences Corporation

08/31/17 / #20170246436

Vacuum-based compliance restoration

A compliance restoration device includes a compliance balloon lumen, a chamber support structure disposed in the compliance balloon lumen and configured to expand to support an expanded volume of the compliance balloon lumen, and a spring assembly configured to cause the chamber support structure to expand by applying a force on a first end of the chamber support structure.. . ... Edwards Lifesciences Corporation

08/31/17 / #20170245992

Transapical method of supplanting an implanted prosthetic heart valve

A method of delivering a prosthetic heart valve to the aortic valve annulus while a patient's heart is beating is disclosed. The method includes accessing the left ventricle through an intercostal incision and forming a puncture in the left ventricle. ... Edwards Lifesciences Corporation

08/24/17 / #20170239044

Heart valves with increased effective orifice area

A prosthetic heart valve for implant in a human. The valve includes a wireform with undulating inflow cusps and outflow commissure posts to which flexible leaflets attach and coapt in a flow area. ... Edwards Lifesciences Corporation

08/17/17 / #20170231765

Apparatus for controlled heart valve delivery

A prosthetic implant delivery assembly can include a prosthetic implant and an elongate catheter. The prosthetic implant can include an expandable stent portion having a longitudinal axis extending from a first end portion of the stent to a second end portion of the stent. ... Edwards Lifesciences Corporation

08/17/17 / #20170231762

Replacement heart valve

A replacement heart valve can have an expandable frame configured to engage a native valve annulus. A valve body can be mounted onto the expandable frame to provide functionality similar to a natural valve. ... Edwards Lifesciences Corporation

08/17/17 / #20170231761

Prosthetic heart valve having multi-level sealing member

Embodiments of a prosthetic heart valve are disclosed. An implantable prosthetic valve may be radially collapsible to a collapsed configuration and radially expandable to an expanded configuration. ... Edwards Lifesciences Corporation

08/17/17 / #20170231759

Prosthetic valve for replacing mitral valve

A prosthetic heart valve includes a collapsible and expandable frame having a main body, an atrial portion, and at least one ventricular anchor. The atrial portion extends radially outwardly relative to the main body and the ventricular anchor extends from a ventricular end of the main body. ... Edwards Lifesciences Corporation

08/17/17 / #20170231756

Devices and systems for docking a heart valve

Expandable docking stations for docking an expandable valve can include a valve seat, one or more sealing portions, and one or more retaining portions. The valve seat can be unexpandable or substantially unexpandable beyond a deployed size. ... Edwards Lifesciences Corporation

08/10/17 / #20170224487

Convertible annuloplasty ring configured to receive an expandable prosthetic heart valve

The invention is a cardiac implant, and associated methods therefore, configured to repair and/or replace a native heart valve, and having a support frame configured to be reshaped into an expanded/changed form in order to receive and/or support an expandable prosthetic heart valve therein. The implant may be configured to have a generally rigid and/or expansion-resistant configuration when initially implanted to replace/repair a native valve (or other prosthetic heart valve), but to assume a generally non-rigid and/or expanded/expandable form when subjected to an outward force such as that provided by a dilation balloon. ... Edwards Lifesciences Corporation

08/10/17 / #20170224484

Methods of rapidly deployable surgical heart valves

A quick-connect heart valve prosthesis that can be quickly and easily implanted during a surgical procedure is provided. The heart valve includes a substantially non-expandable, non-compressible prosthetic valve and a plastically-expandable frame, thereby enabling attachment to the annulus without sutures. ... Edwards Lifesciences Corporation

08/10/17 / #20170224481

Prosthetic heart valve and method

A system for replacing a deficient native aortic valve includes an implantable prosthetic valve having a self-expandable frame and a valve assembly formed with three valve leaflets. The self-expandable frame includes a plurality of support beams, each support beam having a plurality of preformed bores for allowing the valve assembly to be anchored to the frame at least in part by stitching that extends through the leaflets and through the preformed bores of the support beams. ... Edwards Lifesciences Corporation

08/10/17 / #20170224323

Trans-septal closure and port device

A septal closure and port device for implantation in the atrial septum of a patient's heart includes an expandable frame having a central portion defining a lumen, and first and second opposing end portions. The frame is configured to expand and contract between a compressed, tubular configuration for delivery through the patient's vasculature and an expanded configuration in which the first and second end portions extend radially outwardly from the opposite ends of the central portion. ... Edwards Lifesciences Corporation

08/03/17 / #20170216028

Systems for placing a coapting member between valvular leaflets

The present invention relates to devices and methods for improving the function of a defective heart valve, and particularly for reducing regurgitation through an atrioventricular heart valve—i.e., the mitral valve and the tricuspid valve. For a tricuspid repair, the device includes an anchor deployed in the tissue of the right ventricle, in an orifice opening to the right atrium, or anchored to the tricuspid valve. ... Edwards Lifesciences Corporation

07/27/17 / #20170209269

Methods for anchoring a device at a native heart valve annulus

A method and device for anchoring a prosthetic heart valve or annuloplasty ring to a valve annulus in a heart and a method of implanting same is disclosed. The device can include a prosthetic valve or annuloplasty ring with one or more anchors configured to be threaded or otherwise passed underneath a native leaflet and/or subvalvular tissue to secure the device at the native annulus.. ... Edwards Lifesciences Corporation

07/27/17 / #20170209265

Aortic insufficiency repair device and method

This application relates to methods, systems, and apparatus for replacing native heart valves with prosthetic heart valves and treating valvular insufficiency. In a representative embodiment, a support frame configured to be implanted in a heart valve comprises an annular main body formed by a plurality of angled struts, the main body including a plurality of peaks formed by the intersection of respective adjacent struts. ... Edwards Lifesciences Corporation

07/27/17 / #20170209264

Prosthetic valve for replacing mitral valve

A prosthetic apparatus for implantation in a native mitral valve includes a main body for placement within the native mitral annulus. The main body is compressible to a radially compressed state for delivery into the heart and is self-expandable from the compressed state to a radially expanded state for implantation. ... Edwards Lifesciences Corporation

07/27/17 / #20170209263

Method and apparatus for preparing a contoured biological tissue

An assembly and methods for providing a contoured biological tissue are described. The assembly comprises a first plate and a second plate. ... Edwards Lifesciences Corporation

07/06/17 / #20170189183

Prosthetic heart valve and method

A prosthetic heart valve comprises a radially crimpable and radially expandable, net-like, annular support frame and a valve assembly disposed therein, the valve assembly comprising a conduit tapering from an inlet towards an outlet thereof. Some embodiments or the support frame comprise a proximal portion and a distal portion, a diameter of the proximal portion smaller than a diameter of the distal portion. ... Edwards Lifesciences Corporation








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