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Electrophoretics Limited patents


Recent patent applications related to Electrophoretics Limited. Electrophoretics Limited is listed as an Agent/Assignee. Note: Electrophoretics Limited may have other listings under different names/spellings. We're not affiliated with Electrophoretics Limited, we're just tracking patents.

ARCHIVE: New 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 | Company Directory "E" | Electrophoretics Limited-related inventors


Biomolecules involved in alzheimer's disease

. . The invention relates to panels of biomarkers including proteins phosphatase 1 regulatory subunit 14a and/or 2′,3′-cyclic-nucleotide 3′-phosphodiesterase and/or phosphorylated tau or fragments thereof and methods using thereof for diagnosing, staging, treating and assessing the response of a treatment for a neurocognitive disorder characterised by tau toxicity, in particular for alzheimer's disease. The present invention shows that the biomarkers disclosed herein are elevated in the brain of subjects with an advanced stage of a neurocognitive disorder (braak stage v/vi) and/or are regulated in the csf of ad subjects in comparison to cognitively affected non-ad controls; and/or regulated in response to two casein kinase 1 delta inhibitors.. ... Electrophoretics Limited

Materials and methods for diagnosis and treatment of alzheimer's disease

Alzheimer's disease (ad) is the most common type of dementia in aging adults with the number of people living with ad projected to increase, making the search for treatments and tools to diagnose and measure disease progression increasingly urgent. In particular, ideal biomarkers for diagnosis of ad should not only have high specificity for disease versus non-disease and high sensitivity for distinguishing between disease types but also should be able to detect changes at a very early stage of the disease. ... Electrophoretics Limited

Mass labels

The present invention provides a method for labelling one or more analytes in a sample, the method comprising: a) contacting the sample with one or more bifunctional linker reagents having the general formula re1-l1-re2, wherein re1 is a first reactive group, l1 is a linker moiety and re2 is a second reactive group, wherein re1 reacts with an analyte to form a modified analyte; and b) contacting the sample with one or more mass labels, wherein re2 of the bifunctional linker attached to the analyte reacts with a mass label to form a labelled analyte, wherein each mass label is relatable to an analyte by mass spectrometry.. . ... Electrophoretics Limited








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