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Eth Zurich patents (2015 archive)


Recent patent applications related to Eth Zurich. Eth Zurich is listed as an Agent/Assignee. Note: Eth Zurich may have other listings under different names/spellings. We're not affiliated with Eth Zurich, we're just tracking patents.

ARCHIVE: New 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 | Company Directory "E" | Eth Zurich-related inventors


12/31/15 / #20150376647

Designer ph sensor as universal transgene controller

The invention relates to vectors and mammalian cells in a system useful for switching on or switching off gene expression in response to ph and gaseous carbon dioxide, taking advantage of signal transduction of the human proton-activated cell-surface receptor tdag8, ogr1 and/or gpr4 and related receptors to chimeric promoters containing camp-response elements. The systems according to the invention can be used to precisely monitor culture ph within the physiologic range, or also to adjust expression by gaseous c02 which shifts the c02-bicarbonate balance towards hydrogen ions. ... Eth Zurich

12/24/15 / #20150368666

Designer circuit controlling diet-induced obesity

The invention relates to vectors and mammalian cells in a system useful for switching on or switching off gene expression in response to fatty acids, and a method of treating diet-induced obesity. In particular, a synthetic intracellular lipid-sensing receptor was constructed that constantly monitors blood fatty acid levels, processes diet-associated hyperlipidemia and coordinates reversible and adjustable expression of the anorectic peptide hormone pramlintide to reduce dietary intake, blood fat levels and body weight.. ... Eth Zurich

12/24/15 / #20150367588

Apparatus and method for vertical slip forming of concrete structures

Apparatus (10) for vertical (72) slip forming of concrete walls and columns (55). The apparatus comprises an attachment portion (23) for a frame with a slipform assembly inside comprising an extrusion form providing side walls defining a cavity and actuators (20) to adjust the position of the side walls forms essentially arranged along the longitudinal axis of the slipform assembly. ... Eth Zurich

11/12/15 / #20150320632

Apparatus for unloading a user's body weight during a physical activity of said user, particularly for gait training of said user

The invention relates to an apparatus (1) for unloading a user's body weight during a physical activity of said user (4), particularly for gait training of said user (4), comprising: a plurality of ropes (41, 42, 43, 44), wherein each rope (41, 42, 43, 44) extends from an associated drive unit (510, 520, 530, 540), is deflected by a passively displaceable deflection device, e.g. A device that is displaceable by means of the forces in the deflected ropes, and then runs to a first free end (41 a, 42a, 43a, 44a) of the respective rope (41, 42, 43, 44), and a node (60) being coupled to said first free ends (41 a, 42a, 43a, 44a) and being designed to be coupled to said user (4), wherein the drive units (510, 520, 530, 540) are designed to retract and release the respective rope (41, 42, 43, 44) so as to adjust a current rope force (fr) along the respective rope (41, 42, 43, 44), which current rope forces add up to a current resulting force (f) exerted on said user (4) via said node (60) in order to unload the user (4) upon said physical activity. ... Eth Zurich

10/29/15 / #20150309045

Method and tools for the determination of conformation and conformational changes of proteins and of derivatives thereof

A method for the detection of the conformational state of a protein contained in a complex mixture of further proteins and/or other biomolecules, is proposed as well as assays for such a method. The method comprises the following steps: (1) limited proteolysis of the complex mixture under a condition where the protein is in the conformational state to be detected leading to a first fragment sample; (2) denaturation of the first fragment sample to a denaturated first fragment sample; (3) complete fragmentation of the denaturated first fragment sample in a digestion step to a completely fragmented sample; and (4) analytical analysis of the completely fragmented sample for the determination of fragments characteristic of having been the result both the limited proteolysis of step 1 as well as of the complete fragmentation in the digestion step 3. ... Eth Zurich

09/24/15 / #20150267177

Novel methanol dehydrogenase enzymes from bacillus

The present invention relates to a nucleic acid molecule, which encodes a polypeptide having alcohol dehydrogenase activity, in particular methanol dehydrogenase activity, comprising having a nucleotide sequence selected from the group consisting of: (i) a nucleotide sequence as set forth in any one of seq id nos: 1 (mdh2-mga3), 3 (mdh3-mga3), or 5 (mdh2-pb1); (ii) a nucleotide sequence having at least 90% sequence identity, more particularly at least 91, 92, 93, 94, 95, 96, 97, 98 or 99% sequence identity, with a nucleotide sequence as set forth in any one of seq id nos: 1, 3 or 5; (iii) a nucleotide sequence which is degenerate with any one of the nucleotide sequences of seq id nos: 1, 3 or 5; (iv) a nucleotide sequence which is a part of the nucleotide sequence of any one of seq id nos: 1, 3 or 5, or of a nucleotide sequence which is degenerate with a sequence of seq id nos: 1, 3 or 5; (v) a nucleotide sequence encoding all or part of a polypeptide whose amino acid sequence is set forth in any one of seq id nos: 2 (mdh2-mga3), 4 (mdh3-mga3) or 6 (mdh2-pb1); and (vi) a nucleotide sequence encoding all or part of a polypeptide which has an amino acid sequence having at least 90% sequence identity, preferably at least 91, 92, 93, 94, 95, 96, 97, 98 or 99% sequence identity, with an amino acid sequence as set forth in any one of seq id nos: 2, 4 or 6; or a nucleic acid molecule comprising a nucleotide sequence which is complementary to the nucleotide sequence of any one of (i) to (vi). Also provided are recombinant constructs, vectors and host cells comprising such a nucleic acid molecule and polypeptides encoded thereby. ... Eth Zurich

09/03/15 / #20150246907

Pyridomycin based compounds exhibiting an antitubercular activity

Formula (1), x1 represents o or nr6, x2 represents o or nr6, x3 represents o or nr1, r1 represents h or c1 to c3 alkyl, r2 represents h, or linear or branched c1-c8 alkyl optionally including one or more heteroatoms, cyclopropyl, cyclobutyl, cyclohexyl or oxetanyl or amino acid side chain or protected amino acid side chain, or r1 and r2 may form together a saturated, partly saturated or unsaturated 5 or 6 membered ring system, optionally substituted, r3 represents h, cyclopentyl, cyclohexyl, aryl or hydroxyaryl, aryl or hydroxyaryl being optionally substituted by fluorine, or linear or branched c1 to c8 alkyl optionally including a hetero atom, r4 represents phenyl or 5- or 6-membered heterocycles including one or more nitrogen or oxygen atoms optionally substituted with 1 to 4, respectively 5 fluorine atoms, and r6 represents h, or linear or branched alkyl chain having 1 to 3 carbon atoms.. . ... Eth Zurich

08/20/15 / #20150231528

Method and apparatus for multi column chromatographic purification

A method for separating a feed mixture comprising at least two solutes by an intermittent multi column chromatography process with a basic step n performed in a predetermined switching time period. Basic step n comprises two sub steps which are carried out sequentially according to a predetermined step ratio. ... Eth Zurich

08/06/15 / #20150218337

Composite materials and their uses as well as methods for the preparation thereof

. . A reinforced composite material based on a polymer matrix with reinforcement particles embedded therein. The polymer matrix is based on a polymer with soft and hard domains, and the reinforcement particles comprise inorganic nano-platelets in the polymer matrix in a volume fraction in the range of 0.01%-50%, the inorganic nano-platelets have a thickness in the range of 0.3-50 nm, with the proviso that the largest length and width is at least twice as large as the thickness; as well as inorganic micro-platelets in a volume fraction in the range of 1%-90%, wherein the inorganic micro-platelets have a thickness in the range of 10 nm-100 μm, with the proviso that the largest length and width is at least twice as large as the thickness. ... Eth Zurich

08/06/15 / #20150216802

Liposome composition for use in peritoneal dialysis

The present invention is directed to a liposome composition for use in the peritoneal dialysis of patients suffering from endogenous or exogenous toxicopathies, wherein the ph within the liposomes differs from the ph in the intraperitoneal cavity and wherein the ph within the liposome results in a liposome-encapsulated charged toxin. The invention also relates to a pharmaceutical composition comprising said liposomes. ... Eth Zurich

06/25/15 / #20150179401

Method for controlling an interaction between droplet targets and a laser and apparatus for conducting said method

A method for controlling an interaction between droplet targets and a high power and high-repetition-rate laser beam at a laser focus position of the laser beam including providing a droplet generator for generating a train of droplets as a droplet target with a predetermined droplet frequency and velocity in a predetermined direction; providing a high power, high-repetition-rate laser for emitting a pulsed laser beam, which is focused in the laser focus position; aligning the droplet generator such that the train of droplets runs through the laser focus position; generating a train of droplets as a droplet target; and emitting a pulsed laser beam in synchronization with the train of droplets, such that the droplet target interacts with the pulsed laser beam at the laser focus position. . ... Eth Zurich

06/25/15 / #20150177187

Oil removal from a stream of oil-separated sample droplets

An oil removal device for removing oil from a stream (103) of oil-separated sample droplets (104) is disclosed. The oil removal device comprises a sample delivery channel (101) for conducting the stream of sample droplets to an outlet (102). ... Eth Zurich

03/19/15 / #20150078620

Aircraft, methods for providing optical information, method for transmission of acoustic information and method for observing or tracking an object

Provided is an aircraft having a spherical body which generates buoyancy or which may generate buoyancy when filled with gas, wherein the aircraft further comprises four actuation units arranged on the surface of the body for movement of the aircraft in a translation and/or rotation through air, and at least one camera arranged on or in the surface of the body. Further provided is a method for providing optical information to a person in the environment of a flying aircraft, a method for providing optical information about an object and/or surveying of an object, a method for transmission of acoustic information and a method for observing or tracking an object.. ... Eth Zurich

03/19/15 / #20150078563

Accoustic wave reproduction system

A method of and a system for generating an acoustic wave representing reverberations from a desired acoustic environment are described including having a recording surface (11) defined by a spatial distribution of recording transducers (∘) and an emitting surface defined by a spatial distribution of emitting transducers (x), wherein the emitting surface (12) defines a volume within which the recording surface (11) is located, recording an acoustic wave (14) originating from within a volume defined by the recording surface (11) using the recording transducers (x), extrapolating the recorded wave (14) to the emitting surface using wavefield propagator system (is) representing the desired acoustic environment, and emitting the extrapolated wave from the emitting transducers (∘).. . ... Eth Zurich

02/26/15 / #20150057676

Magnetic navigation system with soft magnetic core electromagnets for operation in the non-linear regime

The present invention relates to a magnetic manipulation and navigation system for moving a magnetic element through a body comprising at least six electromagnets (24) with soft-magnetic cores arranged in a predetermined position to said body. It allows for the operation of one or more of the electromagnets in the non-linear regime of the magnetization curve of the cores. ... Eth Zurich

02/05/15 / #20150038892

Patch structures for controlled wound healing

The invention relates to an active surface element (2) for improved healing of cell layer lesions comprising at least one topographically structured surface on a substrate, with a pattern comprising alternating ridges (5) and grooves (6) with a pattern period (p) and extending along a pattern length (l), wherein the pattern period (p) is smaller than 10 μm and the pattern length (l) is larger than 1 mm. The invention furthermore relates to methods of making such an active surface element as well as to bandages, in particular adhesive bandages comprising such active surface elements.. ... Eth Zurich

02/05/15 / #20150038550

Targeting micrornas for metabolic disorders

Provided herein are methods and compositions for the treatment of metabolic disorders. Also provided herein are methods and compositions for the reduction of blood glucose level, the reduction of gluceoneogenesis, the improvement of insulin resistance and the reduction of plasma cholesterol level. ... Eth Zurich

02/05/15 / #20150036132

Metal-dielectric-cnt nanowires for surface-enhanced raman spectroscopy

A sensor with a substrate includes nanowires extending vertically from the substrate, a hafnia coating on the nanowires that provides hafnia coated nanowires, and a noble metal coating on the hafnia coated nanowires. The top of the hafnia and noble metal coated nanowires bent onto one another to create a canopy forest structure. ... Eth Zurich

01/29/15 / #20150030545

Molecular code systems

The present invention relates to a method for protecting and. Recovering nucleic acids. ... Eth Zurich








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