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European Molecular Biology Laboratory patents

Recent patent applications related to European Molecular Biology Laboratory. European Molecular Biology Laboratory is listed as an Agent/Assignee. Note: European Molecular Biology Laboratory may have other listings under different names/spellings. We're not affiliated with European Molecular Biology Laboratory, we're just tracking patents.

ARCHIVE: New 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 | Company Directory "E" | European Molecular Biology Laboratory-related inventors

Microscope module for a microscope arrangement for imaging a sample

A microscope module (300) for imaging a sample (270) is disclosed. The microscope module (300) includes at least one illumination objective (210) for producing an illumination beam along an illumination beam path (215) arranged to illuminate lower surface of the sample (270) and at least one detection objective (220) having a detection path (225). ... European Molecular Biology Laboratory

Microfluidic droplet detection and sorting

The present invention relates to the field of microfluidics and in particular to methods for detecting microfluidic droplets and particles within droplets, as well as sorting the droplets. These methods allow for quantifying properties and activities of the particles within the droplets. ... European Molecular Biology Laboratory

Microfluidic sorting device

A sorting device (10) is disclosed comprising a channel (40) adapted to allow passage of a plurality of samples in a fluid to a first side of a sorting junction (50) and a plurality of braille valves (105) connected by a plurality of connectors to the sorting junction (50). An analysis device (80), such as a camera, is used for analysing ones of the plurality of the samples and adapted to control ones of the plurality of braille valves depending on properties of the analysed ones of the plurality of the samples.. ... European Molecular Biology Laboratory

Influenza a 2009 pandemic h1n1 polypeptide fragments comprising endonuclease activity and their use

The present invention relates to polypeptide fragments comprising an amino-terminal fragment of the pa subunit of a viral rna-dependent rna polymerase possessing endonuclease activity, wherein said pa subunit is from influenza a 2009 pandemic h1n1 virus or is a variant thereof. This invention also relates to (i) crystals of the polypeptide fragments which are suitable for structure determination of said polypeptide fragments using x-ray crystallography and (ii) computational methods using the structural coordinates of said polypeptide to screen for and design compounds that modulate, preferably inhibit the endonucleolytically active site within the polypeptide fragment. ... European Molecular Biology Laboratory

Microfluidic device for the generation of combinatorial samples

The present disclosure relates to a microfluidic device and a method allowing the generating and screening of combinatorial samples. A microfluidic device for producing droplets of at least one sample into an immiscible phase is provided, the device comprising a droplet maker connecting an immiscible phase channel and a sample channel having at least one sample inlet connected to at least one sample inlet channel injecting the at least one sample into the sample channel, wherein the injection of the at least one sample is controlled by at least one sample valve, so that the at least one sample flows either towards a sample waste outlet or into the at least one sample inlet channel, wherein different sample inlet channel of the at least one sample inlet channel have the same hydrodynamic resistance resulting from the length, height and width of each sample inlet channel upstream of the droplet maker.. ... European Molecular Biology Laboratory

Light microscope having a sample stage for cryomicroscopy

In a light microscope (1) for cryomicroscopy, encompassing at least an objective (2) and a sample stage (3) having a cutout (7) for a coolable holder (8) for a sample carrier mount, the cutout (7) being covered by a cover (6), the sample stage (3) is displaceable in two horizontal directions (4). The cover (6) rests floatingly on the sample stage (3), and the objective (2) passes through a cutout (12), corresponding to the objective (2), in the cover (6). ... European Molecular Biology Laboratory

Fluorescent amp-kinase biosensors

The present invention deals with heterotrimeric amp-activated protein kinase (ampk) comprising a fluorophore pair wherein the conformational change can be measured by fret. It represents an advanced tool to screen and identify ampk interactors in vitro and in cells in vivo. ... European Molecular Biology Laboratory

Proteomic sample preparation using paramagnetic beads

. . . . . . . . The present invention relates to a method of reversibly binding polypeptides to a solid phase comprising a hydrophilic surface, preferably for the use in mass spectrometry based proteomics. Kits providing reagents for the method of the invention and uses of said kits.. ... European Molecular Biology Laboratory

Dotam derivatives for therapeutic use

A compound of formula (i), a stereoisomeric form thereof, or a pharmaceutically acceptable salt thereof, wherein the substituents are as defined herein, is provided. The compounds of formula (i) are valuable pharmacologically active compounds and are suitable for the treatment of osteoarthritis. ... European Molecular Biology Laboratory

An optical arrangement and method for imaging a sample

An optical arrangement for imaging a sample is disclosed. The optical arrangement comprises at least one first objective lens and at least one second objective lens, at least one illumination source for producing an illumination beam, detector for imaging radiation from the sample, and at least one mirror for reflecting the radiation from one of the first objective lens or the second objective lens into the detector. ... European Molecular Biology Laboratory

ARCHIVE: New 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009


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