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Fox Chase Cancer Center patents

Recent patent applications related to Fox Chase Cancer Center. Fox Chase Cancer Center is listed as an Agent/Assignee. Note: Fox Chase Cancer Center may have other listings under different names/spellings. We're not affiliated with Fox Chase Cancer Center, we're just tracking patents.

ARCHIVE: New 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 | Company Directory "F" | Fox Chase Cancer Center-related inventors

Combined inhibition of the vitamin d receptor and poly(adp) ribose polymerase (parp) in the treatment of cancer

Methods for treating tumors comprise contacting tumor cells expressing the vitamin d receptor with a vitamin d receptor ligand that inhibits homologous recombination in the tumor cells, and contacting the tumor cells with an amount of a poly(adp) ribose polymerase 1 (parp-1) inhibitor. Inhibiting homologous recombination produces a synergistic therapeutic effect between the vitamin d receptor ligand and parp-1 inhibitor, and may overcome parp-1 resistance in killing tumor cells.. ... Fox Chase Cancer Center

Methods for enriching gene-targeted cells

A gene of interest and the gene encoding hypoxanthine-aminopterin-thymidine (hprt) can be co-targeted for casp9 nuclease-mediated editing or alteration in a cell. Based on whether the hprt gene is altered to encode a non-functional protein, or is not so-altered, the co-targeted cells can be selected and counter-selected. ... Fox Chase Cancer Center

Mechanical compression device for treating or preventing deep vein thrombosis and associated complications

A portable, mechanical compression device for preventing or treating deep vein thrombosis and extremity edema is provided herein. The device includes a frame that is placed in whole or in part around a limb, and a plurality of compression units that compress the limb, thereby mechanically facilitating circulation. ... Fox Chase Cancer Center

Carbon-detected nmr for mapping binding sites in intrinsically disordered regions of a protein

Carbon-detected nmr is well-suited for mapping binding sites in intrinsically disordered regions of a polypeptides, and for mapping of binding motifs in intrinsically disordered regions with single-residue resolution. Provided are methods of carbon-detected nmr for determining the amino acids that mediate the interaction between an intrinsically disordered polypeptide or protein, or an intrinsically disordered region of a polypeptide, and a biomolecule such as another polypeptide or a nucleic acid.. ... Fox Chase Cancer Center

Mice with transgene of ibox peptide inhibitor of group b p21-activated kinases

Mice comprising a transgene encoding a peptide (ibox) inhibitor of group b p21-activated kinase are provided. Also provided are cells, tissue, and organs obtained from such transgenic mice. ... Fox Chase Cancer Center

Poly(adp-ribose) polymerase 1 inhibitors structurally unrelated to nad

Compounds that are not related to nad, and which target parp1-histone h4 interaction are provided, as well as compositions of these compounds, and methods for specific inhibition of poly(adp-ribose) polymerase 1 (parp-1) using these compounds are provided. These parp-1 inhibitors may be used to treat cancer in which parp-1 activation or biologic activity plays a role, including prostate cancer, breast cancer, kidney cancer, ovarian cancer, lymphoma, leukemia, and glioblastoma, among others.. ... Fox Chase Cancer Center

Systems and methods for treating patients having a genetic predisposition to develop prostate cancer

Systems and methods for mitigating prostate cancer development are provided. Peripheral blood cells may be evaluated for the presence or quantity of gamma-h2ax foci, and/or for gene alterations encoding a protein with impaired or lack of function, for example, because the encoded protein is truncated, and correlating with prostate cancer development. ... Fox Chase Cancer Center

Egfr/nedd9/tgf-beta interactome and methods of use thereof for the identification of agents having efficacy in the treatment of hyperproliferative disorders

Compositions and methods for the treatment and diagnosis of cancer are disclosed.. . ... Fox Chase Cancer Center

ARCHIVE: New 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009


This listing is an abstract for educational and research purposes is only meant as a recent sample of applications filed, not a comprehensive history. is not affiliated or associated with Fox Chase Cancer Center in any way and there may be associated servicemarks. This data is also published to the public by the USPTO and available for free on their website. Note that there may be alternative spellings for Fox Chase Cancer Center with additional patents listed. Browse our Agent directory for other possible listings. Page by