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Genia Technologies Inc patents


Recent patent applications related to Genia Technologies Inc. Genia Technologies Inc is listed as an Agent/Assignee. Note: Genia Technologies Inc may have other listings under different names/spellings. We're not affiliated with Genia Technologies Inc, we're just tracking patents.

ARCHIVE: New 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 | Company Directory "G" | Genia Technologies Inc-related inventors


Nanopore arrays

A method of analyzing molecules using a nanopore array including a plurality of cells included on a chip is disclosed. Nanopores are caused to be formed in at least a portion of the plurality of the cells. ... Genia Technologies Inc

Nanopore based molecular detection and sequencing

This disclosure provides systems and methods for molecular identification and polymer (e.g., nucleic acid) sequencing using nanopores. The polymer may be passed through or in proximity to the nanopore and various subunits of the polymer may affect the current flowing through the nanopore. ... Genia Technologies Inc

Nanopore-based sequencing with varying voltage stimulus

A method of analyzing a molecule is disclosed. A voltage source is selectively connected to or disconnected from a capacitor using a switch controlled by a reset signal. ... Genia Technologies Inc

System for detecting electrical properties of a molecular complex

A system for detecting electrical properties of a molecular complex is disclosed. The system includes an electrode electrically coupled to a molecular complex that outputs an electrical signal affected by an electrical property of the molecular complex, wherein the effect of the electrical property of the molecular complex on the electrical signal is characterized by an expected bandwidth. ... Genia Technologies Inc

Nucleic acid sequencing by nanopore detection of tag molecules

This disclosure provides systems and methods for sequencing nucleic acids using nucleotide analogues and translocation of tags from incorporated nucleotide analogues through a nanopore. In aspects, this disclosure is related to compositions, methods, and systems for sequencing nucleic acids using tag molecules and detection of translocation through a nanopore of tags released from incorporation of the molecule.. ... Genia Technologies Inc

Serpentine flow channels for flowing fluids over chip sensors

A nanopore based sequencing system is disclosed. The system includes a plurality of nanopore sensors, each nanopore sensor having a top portion for receiving a fluid. ... Genia Technologies Inc

Temperature regulation of measurement arrays

A system for regulating a temperature of a measurement array is disclosed. The system includes a measurement array including a plurality of sensors, wherein the plurality of sensors are integrated onto an integrated circuit die. ... Genia Technologies Inc

Systems and methods for forming a nanopore in a lipid bilayer

A method of forming a nanopore in a lipid bilayer is disclosed. A nanopore forming solution is deposited over a lipid bilayer. ... Genia Technologies Inc

Printed electrode

A nanopore based sequencing chip package is disclosed. The nanopore based sequencing chip package includes a reservoir defined by a plurality of surfaces. ... Genia Technologies Inc

Electrical enhancement of bilayer formation

A method of forming a plurality of lipid bilayers over an array of cells in a nanopore based sequencing chip is disclosed. Each of the cells comprises a well. ... Genia Technologies Inc

Non-destructive bilayer monitoring using measurement of bilayer response to electrical stimulus

A method of detecting a lipid bilayer formed in a cell of a nanopore based sequencing chip is disclosed. An integrating capacitor is coupled with a lipid membrane, wherein the lipid membrane is between a working electrode and a counter electrode. ... Genia Technologies Inc

Polymerase-template complexes

The present disclosure provides methods and compositions for enhancing the processivity of a polymerase in catalyzing template-dependent dna synthesis in high concentrations of salt. Also disclosed are methods and compositions for enhancing the assembly of polymerase-template complex compatible with active dna synthesis in the presence of low levels of nucleotides and at a high temperature, such as temperatures at or near the melting temperature of the polymerase.. ... Genia Technologies Inc

Exonuclease deficient polymerases

Described herein are polymerase variants that are exonuclease deficient. Some variants retain the strand displacement capability comparable to the wild-type or parental polymerase. ... Genia Technologies Inc

Nanopore arrays

A method of analyzing molecules using a nanopore array including a plurality of cells included on a chip is disclosed. Nanopores are caused to be formed in at least a portion of the plurality of the cells. ... Genia Technologies Inc

08/24/17 / #20170241948

Nucleic acid sequences using tags

This disclosure provides chips, systems and methods for sequencing a nucleic acid sample. Tagged nucleotides are provided into a reaction chamber comprising a nanopore in a membrane. ... Genia Technologies Inc

07/20/17 / #20170203520

Systems and methods for forming a nanopore in a lipid bilayer

Techniques for forming a nanopore in a lipid bilayer are described herein. In one example, an agitation stimulus level such as an electrical agitation stimulus is applied to a lipid bilayer wherein the agitation stimulus level tends to facilitate the formation of nanopores in the lipid bilayer. ... Genia Technologies Inc

07/13/17 / #20170199151

System for communicating information from an array of sensors

A system for communicating information from an array of sensors is disclosed. The system comprises a sensor array that includes a plurality of sensors, wherein each sensor senses a physical property of a material that is in communication with the sensor. ... Genia Technologies Inc

07/13/17 / #20170199150

Nanopore-based sequencing with varying voltage stimulus

A method of analyzing a molecule in a nanopore is disclosed. A voltage is applied across a nanopore that is inserted in a membrane by coupling the nanopore to a voltage source. ... Genia Technologies Inc

07/13/17 / #20170198343

Methods for forming lipid bilayers on biochips

This disclosure provides a biochip comprising a plurality of wells. The biochip includes a membrane that is disposed in or adjacent to an individual well of the plurality of wells. ... Genia Technologies Inc

06/08/17 / #20170159117

Nanopore-based single dna molecule characterization, identification and isolation using speed bumps

The present invention relates to a method of using nanopores to obtain sequence information of sample dnas in ss test dnas. The method comprises using speed bumps to stall the ss test dnas in the nanopores at random positions of the ss test dnas to obtain sequence information of each and every nucleotides of the sample dnas, and to construct the whole sequences of the sample dnas. ... Genia Technologies Inc

06/01/17 / #20170153205

Non-faradaic, capacitively coupled measurement in a nanopore cell array

A method of identifying a molecule is disclosed. A molecule is drawn to a nanopore by applying a first voltage signal to a pair of electrodes during a first period, wherein the first voltage signal causes a first ionic current through the nanopore that is indicative of a property of a portion of the molecule proximate to the nanopore. ... Genia Technologies Inc

04/13/17 / #20170103952

Noise shielding techniques for ultra low current measurements in biochemical applications

A device having an integrated noise shield is disclosed. The device includes a plurality of vertical shielding structures substantially surrounding a semiconductor device. ... Genia Technologies Inc

03/30/17 / #20170091381

Adaptive compression and modification of nanopore measurement data

A system includes a plurality of nanopore cells. Data corresponding to nanopore states of the plurality of nanopore cells is received. ... Genia Technologies Inc

03/30/17 / #20170089858

Encoding state change of nanopore to reduce data size

A system includes a circuit configured to detect a voltage corresponding to an electrical measurement of a nanopore. The system also includes a component configured to compare the voltage to another voltage. ... Genia Technologies Inc

03/30/17 / #20170089857

Differential output of analog memories storing nanopore measurement samples

A nanopore measurement circuit is disclosed. The nanopore measurement circuit includes a nanopore electrode, a first analog memory and a second analog memory. ... Genia Technologies Inc

03/30/17 / #20170088890

Alpha-hemolysin variants

Described herein are engineered alpha-hemolysin subunits having mutated oligomerization domains for assembling into heptameric nanopores in lipid bilayers.. . ... Genia Technologies Inc

03/30/17 / #20170088588

Alpha-hemolysin variants with altered characteristics

Described herein are variants of alpha-hemolysin having at least one mutation selected from t12r, t12k, n17r, n17k or combinations of t12 and n17 mutations. The variants in some embodiments may further comprise h144a. ... Genia Technologies Inc

03/02/17 / #20170059546

Small aperture large electrode cell

A nanopore cell includes a conductive layer and a working electrode disposed above the conductive layer and at the bottom of a well into which an electrolyte may be contained, such that at least a portion of a top base surface area of the working electrode is exposed to the electrolyte. The nanopore cell further includes a first insulating wall disposed above the working electrode and surrounding a lower section of a well, and a second insulating wall disposed above the first insulating wall and surrounding an upper section of the well, forming an overhang above the lower section of the well. ... Genia Technologies Inc

03/02/17 / #20170058397

Electrochemical cell with increased current density

A nanopore cell is disclosed. The nanopore cell includes an electrolyte well having a bottom base, a surrounding sidewall, and a hydrophobic surface above the surrounding sidewall. ... Genia Technologies Inc

02/16/17 / #20170043314

Temperature regulation of measurement arrays

A system for regulating a temperature of a measurement array is disclosed. The system includes a measurement array including a plurality of sensors, wherein the plurality of sensors are integrated onto an integrated circuit die. ... Genia Technologies Inc

02/09/17 / #20170037467

Use of titanium nitride as an electrode in non-faradaic electrochemical cell

A nanopore cell includes a conductive layer. The nanopore cell further includes a titanium nitride (tin) working electrode disposed above the conductive layer. ... Genia Technologies Inc








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