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Georgia State University Research Foundation Inc patents


Recent patent applications related to Georgia State University Research Foundation Inc. Georgia State University Research Foundation Inc is listed as an Agent/Assignee. Note: Georgia State University Research Foundation Inc may have other listings under different names/spellings. We're not affiliated with Georgia State University Research Foundation Inc, we're just tracking patents.

ARCHIVE: New 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 | Company Directory "G" | Georgia State University Research Foundation Inc-related inventors


 new patent  Systems for detecting and quantifying nucleic acids

This invention is based, in part, on our discovery of an essentially one-step, label-free system comprising a sensing unit having a redox current reporter and a nucleic acid sequence complementary to that of a target nucleic acid of interest or sufficiently complementary to that of the target nucleic acid or a sequence therein to specifically bind the target nucleic acid. The sensing unit is bound to an electroconductive substrate (e.g., a carbon- or metal-containing microelectrode (e.g., a gold microelectrode)), and the system includes a signal amplification mechanism that does not rely upon a redox enzyme and thereby overcomes a fundamental limitation of microelectrode dna sensors that fail to generate detectable current in the presence of only small amounts of a target nucleic acid.. ... Georgia State University Research Foundation Inc

Charge-balanced imaging agents

The present invention relates to compositions for and methods of optically imaging tissues or cells using imaging agents having desirable in vivo properties that result in improved signal-to-background ratio.. . ... Georgia State University Research Foundation Inc

Oligosaccharide conjugates for targeting bacteria and uses related thereto

This disclosure relates to conjugates for targeting bacteria and related uses. In certain embodiments, the disclosure relates to methods of transferring a molecule of interest into bacteria comprising mixing bacteria with a non-naturally occurring conjugate under conditions such that the conjugate is transported across the bacterial cell wall. ... Georgia State University Research Foundation Inc

Hydrogen sulfide precursors and conjugates thereof

The present invention provides methods of forming hydrogen sulfide. The methods include contacting a precursor compound with an unmasking agent; wherein the precursor compound comprises a hydrogen sulfide releasing moiety and a masked nucleophile; and wherein the contacting is conducted under conditions sufficient for cyclization of the precursor compound via lactone or lactam formation; thereby releasing hydrogen sulfide from the precursor compound. ... Georgia State University Research Foundation Inc

Compositions and methods for treating copd and other inflammatory conditions

The present invention features, inter alia, pharmaceutical compositions and their use in the preparation of a medicament (e.g., a medicament for inflammation, such as an inflammatory lung disease) or in a therapeutic regimen. The compositions can include at least two active agents: a first agent that inhibits pde4 (e.g., roflumilast) and a second active agent that inhibits the expression or activity of one or more pde4b variants (e.g., pde4b2). ... Georgia State University Research Foundation Inc

Recombinant influenza virus vaccines for influenza and respiratory syncytial virus

Disclosed are recombinant chimeric influenza virus vaccines and live attenuated influenza virus (laiv) vaccines expressing foreign (rsv) neutralizing epitopes or conserved m2e epitopes that are capable of providing broader cross-protection against influenza virus and/or protecting against respiratory syncytial virus (rsv) without vaccine-enhanced rsv disease (erd).. . ... Georgia State University Research Foundation Inc

Cyanine-containing compounds for cancer imaging and treatment

This invention relates generally to cyanine-containing compounds; pharmaceutical compositions comprising cyanine-containing compounds; and methods of using cyanine-containing compounds for cancer cell imaging, cancer cell growth inhibition, and detecting cancer cells, for example. Compounds of the invention are preferentially taken up by cancer cells as compared to normal cells. ... Georgia State University Research Foundation Inc

Surgical articles and methods for detection

Provided herein are articles that comprise a fluorophore (such as a near infrared (nir) agent or a fluorescent protein) affixed to a surgical article. Methods of detecting the surgical article within the body cavity of a subject are also provided. ... Georgia State University Research Foundation Inc

Use of charge-balanced imaging agents for determining renal function

The present invention relates to a method for detecting renal disease and for assessing the efficacy of dialysis treatment using imaging agents having desirable in vivo properties.. . ... Georgia State University Research Foundation Inc

Charge-balanced imaging agents

The present invention relates to compositions for and methods of optically imaging tissues or cells using imaging agents having desirable in vivo properties that result in improved signal-to-background ratio.. . ... Georgia State University Research Foundation Inc

Volatile organic compounds for inhibiting fungal growth

Compositions, devices, and methods are disclosed for treating or preventing fungal infection in an animal are provided. The methods involve exposing the animal to one or more volatile organic compounds (vocs) in a quantity sufficient to inhibit or reduce fungal growth in the animal. ... Georgia State University Research Foundation Inc

Near infrared absorbing fluorescent compositions

Provided herein are heterocyclic near infrared compounds, including near ir compounds defined by formulae i-v described herein. The near infrared compounds can include a cyanine group, a phthalocyanine group, a naphthalocyanine group, a squaraine group, a carbocyanine group, or a combination thereof. ... Georgia State University Research Foundation Inc

Compositions and methods for treating colorectal cancer

The present invention relates to methods of treating a patient who has colorectal cancer and to methods of reducing the likelihood that a patient will develop or experience a recurrence of colorectal cancer. The methods comprise a step of introducing, to the patient, an effective amount of an agent that targets an intestinal h−-coupled di/tripeptide transporter (pept1). ... Georgia State University Research Foundation Inc

Methods and compositions for selective detection of homosysteine

Compositions and methods have been developed for the detection of homocysteine. For example, a fluorescent probe can selectively detect homocysteine based on the redox reaction between the azido group and homocysteine. ... Georgia State University Research Foundation Inc

05/18/17 / #20170139064

Real-time in-situ sub-surface imaging

Systems and methods of real-time in-situ sub-surface imaging are described herein.. . ... Georgia State University Research Foundation Inc

05/11/17 / #20170128456

Carbon monoxide-releasing molecules for therapeutic applications and methods of making and using thereof

Carbon monoxide-releasing organic molecules are described herein. The molecules can be synthesized prior to administration (e.g., ex vivo) or formed in vivo. ... Georgia State University Research Foundation Inc

04/27/17 / #20170114383

Protein production method

Provided herein are methods of producing a heterologous polypeptide and compositions comprising same.. . ... Georgia State University Research Foundation Inc

04/13/17 / #20170102349

Electrochemical methods and compounds for the detection of enzymes

Disclosed are compositions and methods for the electrochemical detection of enzymes, such as enzymes that are indicative of disease, disorders, or pathogens, such as viruses, bacteria, and fungi, or other disorders. These methods can be used in point-of-care diagnostic assays for the detection of disease, disorder, or pathogen (e.g., to identify the strain of pathogen infecting a patient in a healthcare setting). ... Georgia State University Research Foundation Inc

03/23/17 / #20170083387

High-performance computing framework for cloud computing environments

Disclosed are various embodiments for a high-performance computing framework for cloud computing environments. A parallel computing application executable by at least one computing device of the cloud computing environment can call a message passing interface (mpi) to cause a first one of a plurality of virtual machines (vms) of a cloud computing environment to store a message in a queue storage of the cloud computing environment, wherein a second one of the plurality of virtual machines (vms) is configured to poll the queue storage of the cloud computing environment to access the message and perform a processing of data associated with the message. ... Georgia State University Research Foundation Inc








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