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Global Blood Therapeutics Inc patents


Recent patent applications related to Global Blood Therapeutics Inc. Global Blood Therapeutics Inc is listed as an Agent/Assignee. Note: Global Blood Therapeutics Inc may have other listings under different names/spellings. We're not affiliated with Global Blood Therapeutics Inc, we're just tracking patents.

ARCHIVE: New 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 | Company Directory "G" | Global Blood Therapeutics Inc-related inventors


Compounds and uses thereof for the modulation of hemoglobin

Provide herein are compounds and pharmaceutical compositions suitable as modulators of hemoglobin, methods and intermediates for their preparation, and methods for their use in treating disorders mediated by hemoglobin and disorders that would benefit from tissue and/or cellular oxygenation.. . ... Global Blood Therapeutics Inc

Bridged bicyclic kallikrein inhibitors

Provided herein are kallikrein modulating compounds, pharmaceutical compositions comprising the same, and uses thereof.. . ... Global Blood Therapeutics Inc

Compounds and uses thereof for the modulation of hemoglobin

Provide herein are compounds and pharmaceutical compositions suitable as modulators of hemoglobin, methods and intermediates for their preparation, and methods for their use in treating disorders mediated by hemoglobin and disorders that would benefit from tissue and/or cellular oxygenation.. . ... Global Blood Therapeutics Inc

Histone methyltransferase inhibitors

The present disclosure provides certain angular tricyclic compounds that are histone methyltransferases g9a and/or glp inhibitors and are therefore useful for the treatment of diseases treatable by inhibition of g9a and/or glp such as cancers and hemoglobinpathies (e.g., beta-thalassemia and sickle cell disease). Also provided are pharmaceutical compositions containing such compounds and processes for preparing such compounds.. ... Global Blood Therapeutics Inc

Tablets comprising 2-hydroxy-6-((2-(1-isopropyl-1h-pyrazol-5-yl)pyridin-3-yl)methoxy)benzaldehyde

Provided herein are high strength/high drug load tablets comprising 2-hydroxy-6-((2-(1-isopropyl-1h-pyrazol-5-yl)pyridin-3-yl)methoxy)benzaldehyde (“compound 1”), dispersible tablets comprising compound 1, processes of manufacturing such tablets, and methods for treating patients with the tablets. Compound 1 is useful for treating hematological disorders such as sickle cell disease, pulmonary disease such as idiopathic pulmonary fibrosis, and hypoxia and hypoxemia conditions.. ... Global Blood Therapeutics Inc

Substituted benzaldehyde compounds and methods for their use in increasing tissue oxygenation

Provided are substituted benzaldehydes and derivatives thereof that act as allosteric modulators of hemoglobin, methods and intermediates for their preparation, pharmaceutical compositions comprising the modulators, and methods for their use in treating disorders mediate by hemoglobin and disorders that would benefit from increased tissue oxygenation.. . ... Global Blood Therapeutics Inc

Compounds and uses thereof for the modulation of hemoglobin

Provide herein are compounds and pharmaceutical compositions suitable as modulators of hemoglobin, methods and intermediates for their preparation, and methods for their use in treating disorders mediated by hemoglobin and disorders that would benefit from tissue and/or cellular oxygenation.. . ... Global Blood Therapeutics Inc

Process for synthesizing 2-hydroxy-6-((2-(1-isopropyl-1h-pyrazol-5-yl)-pyridin-3-yl)methoxy)benzaldehyde

Disclosed herein are processes for synthesizing 2-hydroxy-6-((2-(1-isopropyl-1h-pyrazol-5-yl)-pyridin-3-yl)methoxy)benzaldehyde (also referred to herein as compound (i)) and intermediates used in such processes. Compound (i) binds to hemoglobin and increases it oxygen affinity and hence can be useful for the treatment of diseases such as sickle cell disease.. ... Global Blood Therapeutics Inc

Compounds and uses thereof for the modulation of hemoglobin

Provide herein are compounds and pharmaceutical compositions suitable as modulators of hemoglobin, methods and intermediates for their preparation, and methods for their use in treating disorders mediated by hemoglobin and disorders that would benefit from tissue and/or cellular oxygenation.. . ... Global Blood Therapeutics Inc

Dosing regimens for 2-hydroxy-6-((2-(1-isopropyl-1h-pyrazol-5-yl)pyridin-3-yl)methoxy)benzaldehyde

Provided herein are methods for treating sickle cell disease, comprising administering to a subject 2-hydroxy-6-((2-(1-isopropyl-1h-pyrazol-5-yl)pyridin-3-yl)-methoxy)benzaldehyde (compound 1), or a polymorph thereof, in certain dosing regimens.. . ... Global Blood Therapeutics Inc








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