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Halozyme Inc patents


Recent patent applications related to Halozyme Inc. Halozyme Inc is listed as an Agent/Assignee. Note: Halozyme Inc may have other listings under different names/spellings. We're not affiliated with Halozyme Inc, we're just tracking patents.

ARCHIVE: New 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 | Company Directory "H" | Halozyme Inc-related inventors


Compositions of adenosine deaminase-2 (ada2), variants thereof and methods of using same

Provided are variant adenosine deaminase 2 (ada2) proteins, conjugates thereof and compositions containing the proteins and/or conjugates. Also provided are methods and uses of the ada2 proteins or conjugates for treating diseases and conditions, such as a tumor or cancer, and in particular any disease or condition associated with elevated adenosine or other associated marker.. ... Halozyme Inc

Soluble glycosaminoglycanases and methods of preparing and using soluble glycosaminoglycanases

The invention relates to the discovery of novel soluble neutral active hyaluronidase glycoproteins (shasegps), methods of manufacture, and their use to facilitate administration of other molecules or to alleviate glycosaminoglycan associated pathologies. Minimally active polypeptide domains of the soluble, neutral active shasegp domains are described that include asparagine-linked sugar moieties required for a functional neutral active hyaluronidase domain. ... Halozyme Inc

Combination therapy with an anti-hyaluronan agent and therapeutic agent

Provided herein is combination cancer therapy effected by administering a polymer-conjugated hyaluronidase, and a tumor-targeted taxane, and optionally a further chemotherapeutic agent such as a nucleoside analog. The combination therapy can be used in methods of treating cancers, and in particular solid tumor cancers.. ... Halozyme Inc

Soluble hyaluronidase glycoprotein (shasegp), process for preparing the same, uses and pharmaceutical compositions comprising thereof

Provided are soluble neutral active hyaluronidase glycoproteins (shasegp's), methods of manufacture, and their use to facilitate administration of other molecules or to alleviate glycosaminoglycan associated pathologies. Minimally active polypeptide domains of the soluble, neutral active shasegp domains are described that include asparagine-linked sugar moieties required for a functional neutral active hyaluronidase domain. ... Halozyme Inc

Combination therapy with a hyaluronan-degrading enzyme and an immune checkpoint inhibitor

Provided are methods of treatments with combinations or compositions containing a soluble hyaluronidase, such as a polymer-modified hyaluronidase, and an immune checkpoint inhibitor treating cancers, including solid and non-solid tumors. The combinations and compositions also are provided.. ... Halozyme Inc








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