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Ibis Biosciences Inc patents


Recent patent applications related to Ibis Biosciences Inc. Ibis Biosciences Inc is listed as an Agent/Assignee. Note: Ibis Biosciences Inc may have other listings under different names/spellings. We're not affiliated with Ibis Biosciences Inc, we're just tracking patents.

ARCHIVE: New 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 | Company Directory "I" | Ibis Biosciences Inc-related inventors


Bioagent detection oligonucleotides

The present invention compositions, methods and systems to identify, detect, and/or quantify bacterial dna in the presence of contaminating non-bacterial dna. In particular, the present invention provides oligonucleotides configured to detect a relatively small amount of bacterial dna in the presence of an overwhelmingly large amount of contaminating human dna.. ... Ibis Biosciences Inc

Modified nucleic acids for nanopore analysis

Provided herein is technology relating to nanopore analysis of nucleic acids and particularly, but not exclusively, to compositions, methods, systems, and kits for analysis of nucleic acids or other assays comprising nucleic acid components.. . ... Ibis Biosciences Inc

Macromolecule delivery to nanowells

Provided herein is technology relating to depositing and/or placing a macromolecule at a desired site for an assay and particularly, but not exclusively, to methods and systems for transporting a macromolecule such as a protein, a nucleic acid, or a protein:nucleic acid complex to an assay site, such as the bottom of a nanopore, a nanowell, or a zero mode waveguide.. . ... Ibis Biosciences Inc

Methods for the synthesis of polyadenylic acid

The present invention provides compositions, kits, and methods for synthesizing polyadenylic acid using polynucleotide phosphorylase, adenosine diphosphate, a buffering agent, and a divalent metal cation. In certain embodiments, the adenosine diphosphate is present at a concentration between about 5.0 mm and about 100 mm, and the buffering agent has a ph around 8.0. ... Ibis Biosciences Inc

Malat-1, a non-coding rna, is a target for the regulation of learning and memory

Provided herein are methods for improving memory or cognitive function in a subject by administering a composition to the brain of the subject, where the composition comprises: i) a compound that increases expression of malat-1 long non-coding rna, ii) a malat-1 long-coding rna nucleic acid sequence, or iii) at least one malat-1 derived pirna nucleic acid sequence. Also provided herein are methods of screening candidate compounds for their ability to modulate the expression of malat-1 long non-coding rna in brain cells. ... Ibis Biosciences Inc

Nucleic acid sequencing by electrochemical detection

Provided herein is technology relating to sequencing nucleic acids and particularly, but not exclusively, to devices, methods, and systems for sequencing-by-synthesis using changes in ph to monitor base addition.. . ... Ibis Biosciences Inc

Alteration of neuronal gene expression by synthetic pirnas and by alteration of pirna function

Provided herein are compositions and methods for the alteration of neuronal methylation by synthetic pirnas or by alteration of pirna function. Such alterations find use in the regulation and control of neural gene expression and concomitant neural functions. ... Ibis Biosciences Inc

Integrated sample preparation systems and stabilized enzyme mixtures

The present invention provides integrated sample preparation systems and stabilized enzyme mixtures. In particular, the present invention provides microfluidic cards configured for processing a sample and generating dna libraries that are suitable for use in sequencing methods (e.g., next generation sequencing methods) or other suitable nucleic acid analysis methods. ... Ibis Biosciences Inc

Methods and compositions for multiple displacement amplification of nucleic acids

Disclosed are methods for multiple displacement amplification of a nucleic acid sequence in a sample. The nucleic acid is contacted with a reaction mixture that includes a set of oligonucleotide primers and a plurality of polymerase enzymes. ... Ibis Biosciences Inc

Sequencing by synthesis using pulse read optics

Provided herein are systems and methods for nucleic acid sequencing by synthesis in a plurality of wells using detectably labeled chain terminating nucleotides with photolabile blocking groups and pulses of photocleaving light. In certain embodiments, the systems and methods provides a plurality of deblock-scan cycles comprising an initial deblock time period followed by a scanning light period, wherein at least one of the following occurs in each deblock-scan cycle: 1) the deblock time period is shorter than the scan time period; 2) the deblock time period is only long enough to deblock the photolabile groups that are part of a primer in less than all of the plurality of wells; or 3) the deblock time period is between 25 and 150 msec and the scan time is at least 200 msec. ... Ibis Biosciences Inc

Rapid whole genome amplification

The present invention provides compositions and methods for rapidly amplifying target nucleic acid (e.g., using whole genome amplification) that allows small amounts of starting nucleic acid to be employed. In certain embodiments, the methods employ compositions that comprise: phi29 polymerase, exo-klenow polymerase and/or klenow polymerase, dntps, primers, and a buffering agent. ... Ibis Biosciences Inc

Compositions and methods for producing single-stranded circular dna

The present invention provides methods, kits, and compositions for producing single-stranded circular dna by pcr. In particular, hairpin primers are provided, and methods of use thereof to produce single-stranded circular dna molecules.. ... Ibis Biosciences Inc

Methods for rapid identification of pathogens in humans and animals

The present invention provides methods of: identifying pathogens in biological samples from humans and animals, resolving a plurality of etiologic agents present in samples obtained from humans and animals, determining detailed genetic information about such pathogens or etiologic agents, and rapid detection and identification of bioagents from environmental, clinical or other samples.. . ... Ibis Biosciences Inc

Capture primers and capture sequence linked solid supports for molecular diagnostic tests

The present invention provides systems, methods, and compositions for performing molecular tests. In particular, the present invention provides methods, compositions and systems for generating target sequence-linked solid supports (e.g., beads) using a solid support linked to a plurality of capture sequences and capture primers composed of a 3′ target-specific portion and a 5′ capture sequence portion. ... Ibis Biosciences Inc

02/02/17 / #20170029879

Improved sensitivity for molecular detection of microbes in the bloodstream

The present disclosure relates to systems and methods for detection of microbes in the bloodstream. In particular, the present invention relates to systems and methods for detection of bacteria and yeast in the bloodstream that are indicative of sepsis.. ... Ibis Biosciences Inc








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