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Idera Inc patents


Recent patent applications related to Idera Inc. Idera Inc is listed as an Agent/Assignee. Note: Idera Inc may have other listings under different names/spellings. We're not affiliated with Idera Inc, we're just tracking patents.

ARCHIVE: New 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 | Company Directory "I" | Idera Inc-related inventors


Database memory monitoring and defragmentation of database indexes

A memory monitoring and selective defragmentation method and system disclosed herein monitor memory usage by and modification of one or more database indexes. The monitoring and selective defragmentation method and system selectively defragment the one or more database indexes based on memory cost savings as opposed to a percentage of fragmentation to improve performance of databases.. ... Idera Inc

Immune modulation with tlr9 agonists for cancer treatment

The present invention relates to methods for treating a tumor, including a metastatic tumor, with tlr9 agonist in combination with an immune checkpoint inhibitor therapy.. . ... Idera Inc

Compositions for inhibiting checkpoint gene expression and uses thereof

The present invention is directed to compounds, compositions, and methods useful for modulating pd1, pdl1, ido1, lag3, tim3, ctla4, ido2, ceacam1, ox40, and/or ox40l mrna or protein expression using gene silencing compounds comprising two or more single stranded antisense oligonucleotides that are linked through their 5′-ends to allow the presence of two or more accessible 3′-ends.. . ... Idera Inc

Containment of data structures with data objects in data modeling tools

A data object design system and method facilitates and generates creation of data objects to contain and, thus, contain data structures within the data objects. The data objects and interaction between the data objects implement a higher level of abstraction between data objects and data entities. ... Idera Inc

Immune regulatory oligonucleotide (iro) compounds to modulate toll-like receptor based immune response

The invention provides novel immune regulatory oligonucleotides (iro) as antagonist of tlrs and methods of use thereof. These iros have unique sequences that inhibit or suppress tlr-mediated signaling in response to a tlr ligand or tlr agonist. ... Idera Inc

Systems and methods for dynamic masking of data

Embodiments disclosed herein may be useful for controlling access to data, and particularly to data intended for restricted access. In at least one embodiment, a system and method for dynamic data masking intercepts input/output (i/o) read requests for data in external memory, determines if the data to be read should be masked, and appropriately, dynamically masks data before the requested data is written into system memory. ... Idera Inc

Treatment of cancer using tlr9 agonist with checkpoint inhibitors

The invention provides methods of inducing an immune response to cancer comprising co-administering to a cancer patient one or more tlr9 agonists and one or more checkpoint inhibitors. Preferably, the one or more tlr9 agonists are administered to the patient via intratumoral (i.t.) administration.. ... Idera Inc

Toll-like receptor 9 antagonist and methods of use thereof

The invention provides antagonist of tlr9 and methods of use thereof. These compounds inhibit or suppress tlr9-mediated signaling. ... Idera Inc

Immune regulatory oligonucleotide (iro) compounds to modulate toll-like receptor based immune response

The invention provides novel immune regulatory oligonucleotides (iro) as antagonist of tlrs and methods of use thereof. These iros have unique sequences that inhibit or suppress tlr-mediated signaling in response to a tlr ligand or tlr agonist. ... Idera Inc

Compositions for inhibiting dux4 gene expression and uses thereof

The present invention is directed to compounds, compositions, and methods useful for modulating dux4 mrna or protein expression using gene silencing compounds comprising two or more single stranded antisense oligonucleotides that are linked through their 5′-ends to allow the presence of two or more accessible 3′-ends.. . ... Idera Inc








ARCHIVE: New 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009



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