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Incyte Corporation patents


Recent patent applications related to Incyte Corporation. Incyte Corporation is listed as an Agent/Assignee. Note: Incyte Corporation may have other listings under different names/spellings. We're not affiliated with Incyte Corporation, we're just tracking patents.

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Methods, systems, and assemblies for cooling an electronic component

A process for depositing a plurality of layers of iridium on a substrate includes: contacting the substrate with an electrolyte composition including: iridium cations protons; biasing the substrate at a first potential; forming iridium on the substrate at the first potential of the substrate; disposing hydrogen on the substrate; self-terminating the forming of iridium on the substrate in response to increasing a coverage of hydrogen on the substrate; oxidizing hydrogen on the substrate by changing a potential of the substrate from the first potential to a second potential; and changing the potential of the substrate from the second potential to a third potential for forming additional iridium on the substrate to deposit a plurality of layers of iridium on the substrate, such that forming the additional iridium on the substrate occurs at the third potential in response to oxidizing the hydrogen on the substrate at the second potential.. . This disclosure is directed to a device and a system for aspirating and dispensing a target analyte, target material, or fluid. A picker may aspirate and dispense the desired material by introducing a pressure gradient. . . . . . . Methods, systems, and assemblies for cooling an electronic component are disclosed. A heat sink assembly includes first and second substrates. ... Incyte Corporation

Fabric wise width reduction

Power consumption is controlled in a fabric of interconnected network switches in which there are queues for data awaiting transmission through the fabric and a plurality of lanes for carrying the data between ports of the switches, a bandwidth manager iteratively determines current queue byte sizes, and assigns respective bandwidths to the switches according to the current queue byte sizes. Responsively to the assigned bandwidths, the bandwidth manager causes a portion of the lanes of the switches to be disabled so as to maintain a power consumption of the fabric below a predefined limit.. ... Incyte Corporation

Method and arrangement in a wireless communication network

Method and arrangement in a first node for requesting a status report from a second node. The first node and the second node are both comprised within a wireless communication network. ... Incyte Corporation

Nonconsecutive file downloading

A data transfer module on a device receives a request from a program to download a file, and accesses a remote service to begin downloading the file. The data transfer module receives bytes of the file from the service and stores those bytes in a temporary file. ... Incyte Corporation

Irradiance based solar panel power point tracking

A power point tracking apparatus employs irradiance detection for performing maximum power point tracking (mppt) of a pv panel. The apparatus controls an operating voltage of a pv panel inverter by regulating the operating voltage of the inverter at a computed optimal voltage based on a detected irradiance of light on the solar panel providing power to the inverter to result in a maximum power generation from the solar panel. ... Incyte Corporation

Solid state battery fabrication

Embodiments of the invention generally relate to solid state battery structures, such as li-ion batteries, methods of fabrication and tools for fabricating the batteries. One or more electrodes and the separator may each be cast using a green tape approach wherein a mixture of active material, conductive additive, polymer binder and/or solid electrolyte are molded or extruded in a roll to roll or segmented sheet/disk process to make green tape, green disks or green sheets. ... Incyte Corporation

All-solid-state lithium battery

Provided is an all-solid-state lithium battery capable of significantly reducing an increase in resistance during repeated use and thereby considerably improving the long-term reliability despite the use of a thick positive electrode plate composed of a sintered body. The all-solid-state lithium battery includes a self-supporting positive electrode plate composed of a sintered body containing a plurality of crystal grains composed of a positive-electrode active material and having a thickness of 20 μm or more, a solid electrolyte layer composed of a lithium-ion conductive material disposed on the positive electrode plate, a lithium-containing negative electrode layer disposed on the solid electrolyte layer, and a positive electrode current collector composed of metal foil having a thickness of from 5 μm to 30 μm, the positive electrode current collector being in unbound contact with the entire surface of a second side of the positive electrode plate remote from the solid electrolyte layer.. ... Incyte Corporation

All-solid-state secondary battery and method of producing the same

The present invention provides an all-solid-state secondary battery and a method for producing the same, wherein it is possible to prevent the collapse of a laminate due to a shearing force occurring in the peripheral portion of the laminate when the laminate is pressed, and the occurrence of an internal short circuit can be prevented. The all-solid-state secondary battery includes a laminate and a plate-shaped insulating member both arranged between the positive electrode collector and the negative electrode collector. ... Incyte Corporation

Partially and fully surface-enabled transition metal ion-exchanging energy storage devices

A surface-enabled, metal ion-exchanging battery device comprising a cathode, an anode, a porous separator, and a metal ion-containing electrolyte, wherein the metal ion is selected from aluminum (al), gallium (ga), indium (in), tin (sn), lead (pb), or bismuth (bi), and at least one of the electrodes contains therein a metal ion source prior to the first charge or discharge cycle of the device and at least the cathode comprises a functional material or nanostructured material having a metal ion-capturing functional group or metal ion-storing surface in direct contact with the electrolyte. This energy storage device has a power density significantly higher than that of a lithium-ion battery and an energy density dramatically higher than that of a supercapacitor.. ... Incyte Corporation

Ionic liquid electrolytes and electrochemical devices comprising same

The present disclosure provides novel ionic liquids with favorable thermal and electrochemical properties. Also provided are devices incorporating the ionic liquids, such as lithium-ion batteries and supercapacitors.. ... Incyte Corporation

Non-aqueous electrolyte and power storage device using same

Provided are a nonaqueous electrolytic solution having an electrolyte salt dissolved in a nonaqueous solvent, the nonaqueous electrolytic solution containing from 0.001 to 5% by mass of 1,3-dioxane and further containing from 0.001 to 5% by mass of at least one selected from a specified phosphoric acid ester compound, a specified cyclic sulfonic acid ester compound, and a cyclic acid anhydride containing a side chain having allyl hydrogen; and an energy storage device using the same. This nonaqueous electrolytic solution is capable of improving electrochemical characteristics at high temperatures and further capable of not only improving a capacity retention rate after a high-temperature cycle test but also decreasing a rate of increase of an electrode thickness.. ... Incyte Corporation

Non-aqueous electrolytic solution and lithium battery

A non-aqueous electrolytic solution comprising a non-aqueous solvent and an electrolyte, which further contains a combination of a nitrile compound and an s=o group-containing compound (or a dinitrile compound) in an amount of 0.001 to 10 wt. % imparts improved cycle performance and storage property to a lithium battery, particularly a lithium secondary battery.. ... Incyte Corporation

Electrolytes for lithium sulfur cells

Disclosed is an electrochemical cell comprising a lithium anode and a sulfur-containing cathode and a non-aqueous electrolyte. The cell exhibits high utilization of the electroactive sulfur-containing material of the cathode and a high charge-discharge efficiency.. ... Incyte Corporation

Non-aqueous electrolytes for lithium-ion batteries comprising an isocyanide

With proviso that c3-c10 (hetero)cycloalkyl is not morpholinyl.. . ... Incyte Corporation

07/12/18 / #20180198162

Ionically conductive compounds and related uses

Articles, compositions, and methods involving ionically conductive compounds are provided. The disclosed ionically conductive compounds may be incorporated into an electrochemical cell (e.g., a lithium-sulfur electrochemical cell, a lithium-ion electrochemical cell, an intercalated-cathode based electrochemical cell) as, for example, a protective layer for an electrode, a solid electrolyte layer, and/or any other appropriate component within the electrochemical cell. ... Incyte Corporation

07/12/18 / #20180198160

Electrolyte solution and lithium ion secondary battery

An electrolyte solution comprising: a non-aqueous solvent; a lithium salt; at least one fluorine-containing compound selected from the group consisting of a fluorine-containing ether compound represented by formula (1) and a fluorine-containing carbonate compound represented by formula (2); and at least one of an ionic liquid represented by formula (3) and an ionic liquid represented by formula (4).. . ... Incyte Corporation

07/12/18 / #20180198158

Production method of negative electrode active material for non-aqueous electrolyte secondary battery, production method of negative electrode for non-aqueous electrolyte secondary battery, and non-aqueous electrolyte secondary battery

A production method of a negative electrode active material for non-aqueous electrolyte secondary batteries containing a silicon compound (siox: 0.5≤1.6) that contains li, includes: making a silicon compound into which the lithium has been inserted contact with a solution b containing a polycyclic aromatic compound or a derivative thereof or both thereof (here, the solution b contains one or more kinds selected from an ether-based solvent, a ketone-based solvent, an ester-based solvent, an alcohol-based solvent, and an amine-based solvent as the solvent); and making the silicon compound contact with a solution c (here, the solution c contains one or more kinds selected from an alcohol-based solvent, a carboxylic acid-based solvent, and water as the solvent). Thereby, a production method of a negative electrode active material for non-aqueous electrolyte secondary batteries is capable of increasing a battery capacity and improving the cycle characteristics.. ... Incyte Corporation

07/12/18 / #20180198157

Non-aqueous electrolyte additive, and non-aqueous electrolyte for lithium secondary battery comprising the same and lithium secondary battery

The present invention relates to a non-aqueous electrolyte additive, and a non-aqueous electrolyte for a lithium secondary battery including the same and a lithium secondary battery, and particularly, to a non-aqueous electrolyte additive having a nitrile group and a propargyl group, and a non-aqueous electrolyte for a lithium secondary battery and a lithium secondary battery, which include the non-aqueous electrolyte additive so that capacity and cycle lifespan characteristics at high temperature can be improved.. . ... Incyte Corporation

07/12/18 / #20180198150

Single-phase perovskite-based solid electrolyte, solid oxide fuel cell comprising same, and method for manufacturing same

This invention relates to a single-phase perovskite-based solid electrolyte, a solid oxide fuel cell including the same, and a method of manufacturing the same. The method of the invention includes stirring and pulverizing a mixed oxide including lanthanum oxide (la2o3), strontium carbonate (srco3), gallium oxide (ga2o3) and magnesium oxide (mgo); and obtaining an lsgm powder by subjecting the pulverized mixed oxide to primary calcination at a first temperature and then secondary calcination at a second temperature that is higher than the first temperature.. ... Incyte Corporation

07/12/18 / #20180198149

Polyphenylsulfone-based proton conducting polymer electrolyte, proton conducting solid polymer electrolyte membrane, electrode catalyst layer for solid polymer fuel cells, method for producing electrode catalyst layer for solid polymer fuel cells, and fuel cell

The present invention addresses the problem of providing a crosslinked film and a hydrocarbon-based proton conducting solid electrolyte having a proton conductivity equal to that of a perfluorosulfonate ion exchange polymer. Disclosed as a means for solving this problem is a proton conducting polymer electrolyte which is composed of a sulfonated polyphenyl compound having a plurality of repeating units, and wherein two or more (for example, four or six) sulfonic groups are introduced into one repeating unit on average. ... Incyte Corporation

07/12/18 / #20180198148

Low temperature solid oxide cells

The present invention provides solid oxide cells such as fuel cells, electrolyzers, and sensors comprising an electrolyte having an interface between an yttria-stabilized zirconia material and a glass material, in some embodiments. Other embodiments add an interface between a platinum oxide material and the yttria-stabilized zirconia material in the electrolyte. ... Incyte Corporation

07/12/18 / #20180198146

Multi-layer fuel cell electrodes with different loadings on the supported catalysts

The performance of a solid polymer membrane electrolyte fuel cell under various operating conditions can be improved via use of electrodes comprising multiple layers of supported catalyst in which the layers comprise different catalyst loadings on their respective supports. Such an electrode comprises a first component catalyst layer adjacent the membrane electrolyte and a second component catalyst layer adjacent the first component layer. ... Incyte Corporation

07/12/18 / #20180198131

Lithium secondary battery

A lithium secondary battery has a positive electrode, an electrolyte containing lithium ions, and a negative electrode current collector having a surface on which a lithium metal or a lithium alloy is deposited/dissolved. In the surface of the negative electrode current collector, a group comprising at least one region whose principal crystal plane is a close-packed plane of the crystal structure or an off plane having an off-angle of 20° or less with respect to the close-packed plane occupies the largest area among three or four groups each comprising at least one region having a principal crystal plane three of whose miller indices are each represented by 0 or 1 or an off-plane having an off-angle of 20° or less with respect to the principal crystal plane, the principal crystal plane being different for each of the three or four groups.. ... Incyte Corporation

07/12/18 / #20180198128

Fluorinated-polymer coated electrodes

Discovering high capacity and high rate cathodic materials is of paramount importance for the further development of electrochemical energy storage devices. Reported herein is a perfluoroalkylated polymer, integrated with an electronically-conductive backbone and an electron transfer catalyst unit that can serve as a new type of cathodic material reaching practical specific capacity of 919 mah/g at 2.5 c discharging rate and over 700 mah/g at 16 c discharging rate. ... Incyte Corporation

07/12/18 / #20180198122

Positive electrode active material for nonaqueous electrolyte secondary batteries, and nonaqueous electrolyte secondary battery

A positive electrode active material for nonaqueous electrolyte secondary batteries, which has high energy density and excellent cycle characteristics. A positive electrode active material for nonaqueous electrolyte secondary batteries of the present invention is represented by general formula linixcoym(1-x-y)o2 (wherein m represents at least one element selected from among metal elements, 0.3≤x<1.0 and 0<y≤0.5) and is configured of particles, each of which is an aggregate of crystallites. ... Incyte Corporation

07/12/18 / #20180198120

Lithium secondary battery

A lithium secondary battery having a positive electrode, a negative electrode, a separator and an electrolyte solution, in which the positive electrode contains a first active material and a second active material each capable of intercalating and deintercalating lithium. The first active material is in the state under which only deintercalation of lithium can be carried out in a battery reaction with the negative electrode immediately after assembly of the lithium secondary battery, and the second active material is in the state under which lithium can be intercalated in the battery reaction with the negative electrode immediately after assembly of the lithium secondary battery. ... Incyte Corporation

07/12/18 / #20180198112

Lithium ion battery electrolyte elimination method

The present invention comprises steps of forming an opening portion in a battery case; aspirating an electrolyte solution from the interior of the battery case through the opening portion and into a sealed and depressurized electrolyte solution recovery trap; injecting a solvent containing no electrolyte from a solvent tank through the opening portion, and into the battery case; and aspirating a mixed solution from the interior of the battery case through the opening portion and into the sealed and depressurized electrolyte solution recovery trap. By performing the above-mentioned process, battery constitutive members including the battery case can be disassembled and recovered efficiently in large quantities.. ... Incyte Corporation

07/12/18 / #20180198111

Electrolyte impregnation apparatus

The present invention relates to an electrolyte impregnation apparatus comprising: a pressing unit comprising a pressing plate that presses a battery cell in which an electrode assembly and an electrolyte are accommodated; and an ultrasonic vibration unit installed to a portion or the whole of the pressing plate to apply ultrasonic vibration to the battery cell.. . ... Incyte Corporation

07/12/18 / #20180197917

High-resistance memory devices

Cross bar array devices and methods of forming the same include first electrodes arranged adjacent to each other and extending in a first direction. Second electrodes are arranged transversely to the first electrodes. ... Incyte Corporation

07/12/18 / #20180197727

Chemical analyzer with membrane

A system for analyzing an analyte is described herein. The system includes a chamber having an inlet and a semi-permeable membrane arranged to seal the inlet. ... Incyte Corporation

07/12/18 / #20180197685

Electrolytic capacitor

An electrolytic capacitor includes an anode body having a dielectric layer; a solid electrolyte layer in contact with the dielectric layer of the anode body; and an electrolytic solution. The electrolytic solution contains a solvent and a solute. ... Incyte Corporation

07/12/18 / #20180197628

Systems, devices, and methods for experiential medication dosage calculations

Systems, devices, and methods for detecting, measuring and classifying meals for an individual based on analyte measurements are described. These results and related information can be presented to the individual to show the individual which meals are causing the most severe analyte response. ... Incyte Corporation

07/12/18 / #20180197069

Generating and identifying functional subnetworks within structural networks

In one aspect, a method includes generating a functional subgraph of a network from a structural graph of the network. The structural graph comprises a set of vertices and structural connections between the vertices. ... Incyte Corporation

07/12/18 / #20180196944

Applications of a binary search engine based on an inverted index of byte sequences

Techniques for searching an inverted index associating byte sequences of a fixed length and files that contain those byte sequences are described herein. Byte sequences comprising a search query are determined and searched in the inverted index. ... Incyte Corporation

07/12/18 / #20180196943

Binary search of byte sequences using inverted indices

Techniques for searching an inverted index associating byte sequences of a fixed length and files that contain those byte sequences are described herein. Byte sequences comprising a search query are determined and searched in the inverted index, and an intersection of the results is determined and returned as a response to the search query. ... Incyte Corporation

07/12/18 / #20180196839

Real time index generation

A computer implemented method of real-time index generation of data in a data stream during data stream recording to an archive, the method including: receiving a byte of the data stream; and adding an entry for the byte of the data stream to a bitmap index of bytes, the bitmap index indicating, for each possible byte value, a location in the archive of each of occurrences and non-occurrences of the byte value by a sequence of bit values in the bitmap index, wherein the bitmap index includes a count of a number of occurrences for each byte value, wherein a plurality of run length encoding (rle) schemes are applied to sub-sequences of identical bit values for each byte value in the index, each rle scheme having a different encoding type identified by an encoding type indicator and indicating a bit value and a number of bits in a sub-sequence, and wherein a pair of rle encoded sub-sequences of indications of non-occurrence of a byte value implies a single indication of an occurrence of the byte value between the pair.. . ... Incyte Corporation

07/12/18 / #20180196777

Methods to send extra information in-band on inter-integrated circuit (i2c) bus

System, methods and apparatus are described that offer improved performance of an inter-integrated circuit (i2c) bus. Primary data may be encoded in first signaling in accordance with i2c bus protocols, and the first signaling may be combined with second signaling to obtain combined signaling for transmission on an i2c bus. ... Incyte Corporation

07/12/18 / #20180196770

Forced compression of single i2c writes

Systems, methods, and apparatus are described that enable a physical layer interface of a device coupled to a serial bus to combine two or more single-byte write transactions to obtain a multi-byte write transaction. A method includes buffering a first single-byte transaction addressed to a first register at a first address of a slave device in a first-in-first-out buffer of the physical layer, receiving at the physical layer a second single-byte transaction addressed to a second register at a second address of the slave device coupled to the serial bus, determining in the physical layer whether the second address is incrementally greater than the first address, combining the second single-byte transaction with the first single-byte transaction to obtain a multi-byte transaction, replacing the first single-byte transaction with the multi-byte transaction in the first-in-first-out buffer, and transmitting a sequence of transactions output by the first-in-first-out buffer over the serial bus.. ... Incyte Corporation

07/12/18 / #20180196648

Providing dynamic instrumentation using domain-specific monitoring-language-to-kernel-bytecode compilation

Providing dynamic instrumentation using domain-specific monitoring-language-to-kernel-bytecode compilation is disclosed. An instrumentation program file is converted by a compilation engine into multiple bytecode sections. ... Incyte Corporation

07/12/18 / #20180196060

Mass spectrometry imaging of glycans from tissue sections and improved analyte detection methods

The presently disclosed subject matter provides methods using mass spectrometry for direct profiling of n-linked glycans from a biological sample. In addition, the embodiments of the present invention also disclose novel methods, known as targeted analyte detection (tad), for improving the detection limit of maldi-ms. ... Incyte Corporation

07/12/18 / #20180196058

Multiplexed detection with isotope-coded reporters

Some aspects of this invention provide reagents and methods for the sensitive, quantitative and simultaneous detection of target analytes in complex biological samples by liquid chromatography tandem mass spectrometry (lc ms/ms). Some aspects of this invention provide affinity reagents encoded with mass reporters for the sensitive and quantitative translation of an analyte of interest into a mass tag. ... Incyte Corporation

07/12/18 / #20180196043

Lateral flow assays for non-diagnostic analytes

Methods of determining whether a non-diagnostic analyte is present in a non-diagnostic sample are provided. Aspects of the methods include applying a non-diagnostic sample to a sample receiving region of a lateral flow assay device and reading a detection region to determine whether a non-diagnostic analyte is present in the non-diagnostic sample. ... Incyte Corporation

07/12/18 / #20180196042

Homogeneous competitive lateral flow assay

A patient or animal side method and assay for eliminating the hook effect in the detection of a high molecular weight target analyte such as an acute phase protein in a bodily fluid in which the target analyte includes a member of a specific binding pair including applying the sample to a solid phase carrier material, generating a signal in accordance with downstream movement of the labelled first or second members and the target analyte to bind with the complementary immobilised first or second members, and detecting the presence of the target analyte in accordance with the signal generated at the complementary immobilised first or second members.. . ... Incyte Corporation

07/12/18 / #20180196039

Nano-enzyme containers for test elements

The present invention relates to a test element for the detection of an analyte comprising an enzyme, wherein the enzyme is incorporated in a nanocapsule.. . ... Incyte Corporation

07/12/18 / #20180196019

Modifier stream elution of trap column for multidimensional compressible fluid-based chromatography

A method of performing a chromatographic separation includes modulating a portion of a flowstream to a trap column to retain at least one analyte from the flowstream on the trap column. A flow of a modifier is provided through the trap column to generate an elution comprising the at least one analyte. ... Incyte Corporation

07/12/18 / #20180196012

Devices and methods for quartz enhanced photoacoustic spectroscopy

In quartz-enhanced photoacoustic spectroscopy (qepas), an analyte (typically in gas phase) generates a pressure wave in response to incident laser light. A quartz tuning fork (qtf) resonant at the frequency of the pressure wave transduces the pressure wave into an electrical signal. ... Incyte Corporation

07/12/18 / #20180196009

Measurement of analyte with an acoustic wave sensor

A sensitive assay for an analyte employing an acoustic wave sensor. A label which has a higher dissipative capacity than the analyte is adhered to the sensing surface of an acoustic wave sensor through the analyte such that the body of the label is spaced apart from and anchored to the surface of the acoustic wave sensor by a distance of 15 to 250 nm. ... Incyte Corporation

07/12/18 / #20180196000

Underfill detection system for a biosensor

A biosensor has an underfill detection system that determines whether a sample of a biological fluid is large enough for an analysis of one or more analytes. The underfill detection system applies an excitation signal to the sample, which generates an output signal in response to the excitation signal. ... Incyte Corporation

07/12/18 / #20180195995

Gas sensor for detecting hydrocarbons

A gas sensor includes a housing (22) having disposed therein a membrane electrode assembly comprising a sensing electrode (14), a counter electrode (16), and a solid polymer electrolyte (12) disposed between the sensing electrode and the counter electrode. The sensing electrode comprises a first catalyst comprising noble metal nanoparticles (34). ... Incyte Corporation

07/12/18 / #20180195994

Systems, devices, and methods for measuring whole blood hematocrit based on initial fill velocity

Methods for determining the hematocrit of a blood sample, and devices and systems used in conjunction with the same. The hematocrit value can be determined on its own, and further, it can be further used to determine a concentration of an analyte in a sample. ... Incyte Corporation

07/12/18 / #20180195938

Biological material measuring instrument

A biological material measuring instrument is described. The biological material measuring instrument includes a rotating body and a main body. ... Incyte Corporation

07/12/18 / #20180195904

Dedicated transformation spectroscopy

The invention relates to a multi-channel spectrometer device (10) for detecting/quantifying a predetermined analyte (5) in a medium (6). The device (10) comprises an input (11) for receiving radiation (7), a first plurality of optical modulators (12) adapted for transforming the radiation (7) in accordance with a first transfer function, and a second plurality of optical modulators (13) adapted for transforming the radiation (7) in accordance with a second transfer function. ... Incyte Corporation

07/12/18 / #20180195184

Electrolytic system and reduction method for electrochemical carbon dioxide utilization, alkali carbonate preparation and alkali hydrogen carbonate preparation

The present disclosure relates to electrolysis. The teachings thereof may be embodied in a reduction process and/or an electrolysis system for electrochemical carbon dioxide utilization wherein carbon dioxide is introduced into an electrolysis cell and reduced at a cathode. ... Incyte Corporation

07/12/18 / #20180195132

Oligodendroglioma drive genes

Oligodendrogliomas are the second most common malignant brain tumor in adults. These tumors often contain a chromosomal abnormality involving a pericentromeric fusion of chromosomes 1 and 19, resulting in losses of the entire short arm of the former and the long arm of the latter. ... Incyte Corporation

07/12/18 / #20180195111

16s ribosomal rna universal primers and use thereof in microbiological analysis and diagnostics

The subject-matter of the invention is a pair of primers, a method of microbiological analysis of biomaterial, application of ngs sequencing method in microbiological diagnostics of blood and diganostics set. An innovative method of body fluids diagnosing from microbiological perspective i.e. ... Incyte Corporation

07/12/18 / #20180195044

Methods of enhancing fibroblast therapeutic activity

Disclosed are compositions of matter, cells, protocols and procedures useful for augmentation of one or more therapeutic activities of fibroblast cellular populations. In one embodiment fibroblasts are pretreated with growth factor-comprising composition(s), wherein the growth factor(s) may be cytokines, peptides, and/or proteins. ... Incyte Corporation

07/12/18 / #20180194884

Modified polytetrafluoroethylene fine powder and method for its production, and method for producing tube or hose

A modified polytetrafluoroethylene fine powder which is a fine powder of a non-melt-moldable modified polytetrafluoroethylene, characterized in that the modified polytetrafluoroethylene comprises units derived from tetrafluoroethylene, units derived from a perfluoroalkyl vinyl ether represented by cf2═cfo—cnf2n+1 (wherein n is an integer of from 1 to 6), and units derived from a perfluoroalkylethylene represented by ch2═ch—cmf2m+1 (wherein m is an integer of from 3 to 6), and that the content of the units derived from the perfluoroalkyl vinyl ether is from 0.1 to 0.25 mass % and the content of the units derived from a perfluoroalkylethylene is from 0.001 to 0.1 mass %, based on all monomer units in the modified polytetrafluoroethylene.. . ... Incyte Corporation

07/12/18 / #20180194850

Antagonistic anti-tumor necrosis factor receptor superfamily antibodies

Antagonistic tnfr superfamily polypeptides, such as antibodies and antigen-binding fragments thereof, and the use of these polypeptides to inhibit the proliferation of regulatory t cells (t-regs). For example, antibodies of the invention include antagonistic tnfr2 antibodies and antigen-binding fragments thereof, and can be used to suppress the t-reg-mediated deactivation of tumor reactive t-lymphocytes, as well as to treat a wide variety of cancers and infectious diseases.. ... Incyte Corporation

07/12/18 / #20180194806

Induction of tumor immunity by variants of folate binding protein

The present invention is directed to variants of antigens comprising folate binding protein epitopes as a composition associated with providing immunity against a tumor in an individual. The variant is effective in inducing cytotoxic t-lymphocytes but preferably not to the extent that they become sensitive to silencing by elimination, such as by apoptosis, or by anergy, as in unresponsiveness.. ... Incyte Corporation

07/12/18 / #20180194650

Brine feed system

The present invention relates to an electrolytic cell producing oxidants that utilizes a vacuum venturi system to meter saturated brine to the water stream to produce the correct conductivity electrolyte for operation of the electrolytic cell. The present invention comprises a venture eductor configured to accept brine from a brine source and to communicate brine to the chlorine generation system, a first control device to discourage communication of brine from the venture eductor to the brine source, and a second control device to control the rate of flow of brine from the brine source to the venture eductor.. ... Incyte Corporation

07/12/18 / #20180194648

Electrolytic apparatus

Provided is an electrolytic apparatus including an electrolytic tank. The electrolytic tank includes a cathode chamber provided therein with a negative electrode and an anode chamber provided therein with a positive electrode. ... Incyte Corporation

07/12/18 / #20180194620

Thin film substrates including crosslinked carbon nanostructures and related methods

A method of making a thin film substrate involves exposing carbon nanostructures to a crosslinker to crosslink the carbon nanostructures. The crosslinked carbon nanostructures are recovered and disposed on a support substrate. ... Incyte Corporation

07/12/18 / #20180193834

Capillary-action microfluidic device for point-of-care diagnostics

A testing device that integrates nucleic acid isolation, isothermal amplification and detection wherein a sample and reagents are transported through a capture/binding membrane by capillary forces and the positioning of a slidebar that supports said binding membrane. Flow control and fluid actuation are effected by the position of said slidebar which makes a fluidic connection through the capture membrane situated between a reservoir of liquid on the device and an absorbing pad, and where a sequence of operations for sample loading, washing, optionally amplification, and optical detection of analytes can be done conveniently and rapidly at the point of care. ... Incyte Corporation

07/12/18 / #20180193812

Use of an ampholyte copolymer as colloidal stabilizer

And wherein the ampholyte copolymer has more cationic charges than anionic charges, wherein the cationic charges of the ampholyte copolymer are exclusively due to the at least one quaternary ammonium group of the cationic monomer.. . ... Incyte Corporation

07/12/18 / #20180193550

Fluid management system and methods

A hysteroscopic fluid management system includes a saline source with an electrolyte concentration, at least one pressure mechanism for circulating saline to and from a targeted site and through a filter having filter characteristics back to the source, and a controller. The controller provides a saline inflow in a first flow path to the site and a saline outflow in a second flow path from the site through the filter and back to the source at a controlled flow rate. ... Incyte Corporation

07/12/18 / #20180193390

Bioactive animal feed

The invention relates to a food supplement comprising or consisting of archaebacteria, and particularly methanogenic archaebacteria, to be used as a probiotic adjunct for animal feed. The supplement can be provided to e.g. ... Incyte Corporation

07/12/18 / #20180193384

Anti third party central memory t cells, methods of producing same and use of same in transplantation and disease treatment

A method of generating an isolated population of cells comprising anti-third party cells having a central memory t-lymphocyte (tcm) phenotype, the cells being tolerance-inducing cells and/or endowed with anti-disease activity, and capable of homing to the lymph nodes following transplantation is disclosed. The method comprising: (a) contacting peripheral blood mononuclear cells (pbmc) with a third party antigen or antigens in the presence of il-21 so as to allow enrichment of antigen reactive cells; and (b) culturing the cells resulting from step (a) in the presence of il-21, il-15 and il-7 in an antigen free environment so as to allow proliferation of cells comprising the central memory t-lymphocyte (tcm) phenotype.. ... Incyte Corporation

07/12/18 / #20180193323

Thiazolecarboxamides and pyridinecarboxamide compounds useful as pim kinase inhibitors

The present disclosure describes thiazole and pyridine carboxamide derivatives, their compositions and methods of use. The compounds inhibit the activity of the pim kinases and are useful in the treatment of diseases related to the activity of pim kinases including, e.g., cancer and other diseases.. ... Incyte Corporation

07/12/18 / #20180193252

Cosmetic compositions and method of making the same

The present invention generally relates to cosmetic compositions comprising serum derived from cultured keratinocyte and fibroblast cells. The invention also relates to methods of producing serum for use in the cosmetic compositions through novel cell culture techniques.. ... Incyte Corporation

07/12/18 / #20180193217

Apparatus to apply forces in a three-dimensional space

The present invention relates to a robotic system useful to unload the object/person from its weight. The robotic system is useful in locomotor rehabilitation programs and allows the manipulation of forces in a three-dimensional space with far lower actuator requirements and a much higher precision than prior-art systems. ... Incyte Corporation

07/12/18 / #20180192981

Combination of an x-ray tube and a source grating with electron beam manipulation

Novel and advantageous systems and methods for performing x-ray imaging by using an x-ray source with source grating functionality incorporated therein are provided. An electron beam can be electromagnetically manipulated such that the x-ray source emits radiation in a pattern that is the same as if the radiation had already passed through a source grating.. ... Incyte Corporation

07/12/18 / #20180192963

Model based variable risk false glucose threshold alarm prevention mechanism

Methods of determining when to activate an analyte, e.g. Glucose, related alarm, such as a hypoglycemia alarm, of a continuous analyte monitor is provided. ... Incyte Corporation

07/12/18 / #20180192932

Lyotropic liquid crystal coated analyte monitoring device and methods of use

Analyte sensor assemblies comprising: an electrochemical sensor for determining a concentration of an analyte and an electrochemical sensor control unit. The electrochemical sensor comprising a working electrode having a sensing layer and a non-crosslinked cubic phase lyotropic liquid crystal membrane disposed over the sensing layer, the sensing layer comprising an analyte-responsive enzyme, and a counter electrode in communication with the working electrode. ... Incyte Corporation

07/12/18 / #20180192927

Analyte monitoring and management device and method to analyze the frequency of user interaction with the device

Methods and devices to monitor the level of at least one analyte are provided.. . ... Incyte Corporation

07/12/18 / #20180192926

Device and method for determining analyte levels

Devices and methods for determining analyte levels are described. The devices and methods allow for the implantation of analyte-monitoring devices, such as glucose monitoring devices that result in the delivery of a dependable flow of blood to deliver sample to the implanted device. ... Incyte Corporation

07/12/18 / #20180192644

Aqueous electrolyte-containing adjuvant compositons, active ingredient-containing compositions and the use thereof

The invention relates to adjuvant compositions which contain a) one or more polyalkylene glycol sulfate salts or polyalkylene glycol sulfonate salts, b) water, and c) one or more electrolytes dissociated into ions. Said adjuvant compositions can be preferably used combined with pharmaceutical active ingredients, agrochemical active ingredients, biocides or repellents which have a high electrolyte content.. ... Incyte Corporation

07/05/18 / #20180191801

Adaptively updating content delivery network link in a manifest file

. . . . . . . . . . . . . . An online system more efficiently streams multimedia content over the internet for play back on client devices with varying computing power and network bandwidths by generating enhanced manifest files that more efficiently identify suitable media representations of the multimedia content. Each media representation has multiple media segments according to predefined byte ranges and a manifest file, which identifies location of the media file, bitrates, resolution, byte range, total duration, and other metadata. ... Incyte Corporation

07/05/18 / #20180191799

Effectively fetch media content for enhancing media streaming

An online system more efficiently streams multimedia content over the internet for play back on client devices with varying computing power and network bandwidths by generating enhanced manifest files that more efficiently identify suitable media representations of the multimedia content. Each media representation has multiple media segments according to predefined byte ranges and a manifest file, which identifies location of the media file, bitrates, resolution, byte range, total duration, and other metadata. ... Incyte Corporation

07/05/18 / #20180191598

Method, terminal and system for cluster terminal to feed back downlink channel information

A method, a terminal and a system for a cluster terminal to feedback downlink channel information are provided. In the method, a cluster terminal in an idle state configures a group call context and measures a current downlink channel in a preset period, after a group call signaling sent by a base station is received; sends a rrc connection request carrying a measurement result to the base station after determining that the measurement result meets a preset report triggering condition, where the base station modifies an air interface resource configuration when determining that a preset condition for modifying the air interface resource configuration is met according to the measurement result and sends an instruction carrying the modified air interface resource configuration to the cluster terminal; and receives group call data according to the instruction after the instruction is received.. ... Incyte Corporation

07/05/18 / #20180191587

Customizing manifest file for enhancing media streaming

An online system more efficiently streams multimedia content over the internet for play back on client devices with varying computing power and network bandwidths by generating enhanced manifest files that more efficiently identify suitable media representations of the multimedia content. Each media representation has multiple media segments according to predefined byte ranges and a manifest file, which identifies location of the media file, bitrates, resolution, byte range, total duration, and other metadata. ... Incyte Corporation

07/05/18 / #20180191586

Generating manifest file for enhancing media streaming

An online system more efficiently streams multimedia content over the internet for play back on client devices with varying computing power and network bandwidths by generating enhanced manifest files that more efficiently identify suitable media representations of the multimedia content. Each media representation has multiple media segments according to predefined byte ranges and a manifest file, which identifies location of the media file, bitrates, resolution, byte range, total duration, and other metadata. ... Incyte Corporation

07/05/18 / #20180191507

Decryption and variant processing

A plurality of byte ranges including at least one encrypted byte range forms a variant sample for providing a digital watermark in content output by a player device. The plurality of byte ranges is ordered in a secured memory, and stored in an unsecured memory including one or more encrypted byte ranges for further processing of the ordered plurality of byte ranges. ... Incyte Corporation

07/05/18 / #20180191187

Active battery management system

A method for charging a battery cell includes first transferring of energy from a power source to a plurality of capacitive regions in the battery cell followed by transferring of charge stored in the plurality of capacitive regions of the battery cell into at least an electrolytic mixture that comprises the battery cell and electrodes immersed in the electrolyte mixture. The capacitive regions in the battery cell comprise capacitive double layers between the electrolyte mixture and particles of active material that comprise the battery cell. ... Incyte Corporation

07/05/18 / #20180191044

System and method for metal-air anode renovation

A method for renovation of a consumed anode in a metal-air cell without dismantling the cell comprises circulating electrolyte through the cell to evacuate used slurry from the cell, circulating electrolyte with fresh slurry into the cell and allowing sedimentation of the fresh slurry inside the cell to form an anode and compacting the slurry to reduce the gaps between its particles. A meta-air cell enabling renovation of a consumed anode without dismantling the cell defining first outer face of the cell, air cathode layer adjacent the porous wall, separator wall disposed on the inner face of the air cathode layer, cell space volume to contain electrolyte and metal granules slurry, current collector layer to form an anode, made of current conductive material disposed in the space and flexible wall defining a second outer face of the cell wherein the flexible wall is adapted to be pushed towards inside of the cell subject to pressure applied to its outer face, thereby to reduce the volume of the space.. ... Incyte Corporation

07/05/18 / #20180191035

Biomedical energization elements with polymer electrolytes and cavity structures

Designs, strategies and methods to form energization elements comprising polymer electrolytes are described. In some examples, the biocompatible energization elements may be used in a biomedical device. ... Incyte Corporation

07/05/18 / #20180191033

Electrolyte additives for electrochemical devices

A system and method for stabilizing electrodes against dissolution and/or hydrolysis including use of cosolvents in liquid electrolyte batteries for three purposes: the extension of the calendar and cycle life time of electrodes that are partially soluble in liquid electrolytes, the purpose of limiting the rate of electrolysis of water into hydrogen and oxygen as a side reaction during battery operation, and for the purpose of cost reduction.. . ... Incyte Corporation

07/05/18 / #20180191032

Electrolyte and lithium-ion battery

The present disclosure provides an electrolyte and a lithium-ion battery. The electrolyte comprises: an organic solvent; a lithium salt dissolved in the organic solvent; and an additive. ... Incyte Corporation

07/05/18 / #20180191031

Non-aqueous electrolyte additive, non-aqueous electrolyte comprising the same, and lithium secondary battery including non-aqueous electrolyte

The present invention relates to: a non-aqueous electrolyte additive comprising, as a substituent, at least one cyano group and/or at least one fluorine element; a non-aqueous electrolyte for a lithium secondary battery, comprising the same; and a lithium secondary battery including the non-aqueous electrolyte.. . ... Incyte Corporation

07/05/18 / #20180191030

Lithium-ion electrochemical accumulator with improved leak tightness

The invention relates to a lithium-ion electrochemical accumulator—or li-ion battery—having improved leak tightness of the liquid electrolyte contained therein. The architecture of the accumulator may be monopolar or bipolar. ... Incyte Corporation

07/05/18 / #20180191029

Gel electrolyte and applications thereof

A gel electrolyte and applications thereof are provided. The composition of the gel electrolyte includes an organic base and hydrogen ion exchanged inorganic nano-platelets dispersed in the organic base. ... Incyte Corporation

07/05/18 / #20180191028

Annealed garnet electrolyte separators

Set forth herein are pellets, thin films, and monoliths of lithium-stuffed garnet electrolytes having engineered surfaces. These engineered surfaces have a list of advantageous properties including, but not limited to, low surface area resistance, high li+ ion conductivity, low tendency for lithium dendrites to form within or thereupon when the electrolytes are used in an electrochemical cell. ... Incyte Corporation

07/05/18 / #20180191027

Nonaqueous electrolyte secondary battery

A nonaqueous electrolyte secondary battery includes a positive electrode, a negative electrode having a negative electrode active material, and a separator containing an electrolyte. The electrolyte includes an electrolyte salt, a nonaqueous solvent into which the electrolyte salt can be dissolved, a first additive selected from predetermined oxalate compounds and disulfonic acid ester compounds, and a second additive that has a reduction potential less than the reduction potential of the first additive. ... Incyte Corporation

07/05/18 / #20180191026

Protective layer having improved contacting for lithium cells and/or lithium batteries

A separator of a lithium cell or battery includes (i) a protective layer that includes at least one single lithium-ion conducting polyelectrolyte, a lithium-ion conducting or lithium-ion conductive block copolymer, and/or an inorganic lithium-ion conductor, and (ii) a contact layer that includes at least one polymer electrolyte made of (a) a lithium-ion conductive polymer that includes a main chain and at least one side chain and (b) at least one lithium conducting salt.. . ... Incyte Corporation

07/05/18 / #20180191025

Solid-state battery

In one example, a battery includes a cathode, an anode, and a layer between the cathode and the anode. The cathode includes a solid-state electrolyte. ... Incyte Corporation

07/05/18 / #20180191024

Method of preparing secondary battery

The present invention relates to a method of preparing a secondary battery which includes providing a film layer, which includes a first solvent having a melting temperature of 25° c. Or more and a viscosity of 1.5 cp or more, between a separator and an electrode (step 1), preparing an electrode assembly by using the electrode, the film layer, and the separator (step 2), and accommodating the electrode assembly in a case, injecting an injection solution including a second solvent, and sealing the case (step 3), and a secondary battery prepared by the method. ... Incyte Corporation

07/05/18 / #20180191022

Non-aqueous electrolyte battery and method for manufacturing same

Where x is si, ge or sn, r1, r2 and r3 independently represent an alkyl group having 1 to 10 carbon atoms, an alkenyl group having 2 to 10 carbon atoms, or an aryl group having 6 to 10 carbon atoms; and some or all of hydrogen atoms are optionally substituted by a fluorine atom.. . ... Incyte Corporation

07/05/18 / #20180191021

Lithium secondary battery including non-aqueous electrolyte solution

In the lithium secondary battery including a non-aqueous electrolyte solution for a lithium secondary battery of the present invention, since the non-aqueous electrolyte solution may form a robust solid electrolyte interface (sei) on the negative electrode during initial charge and may prevent decomposition of the surface of the positive electrode and an oxidation reaction of the electrolyte solution during a high-temperature cycle, excellent low-temperature output characteristics as well as improved high-temperature storage characteristics and life characteristics may be achieved.. . ... Incyte Corporation

07/05/18 / #20180191017

Aqueous methods for forming titanium catecholate complexes and associated compositions

Titanium catecholate complexes can be desirable active materials for flow batteries and other electrochemical energy storage systems, particularly when incorporated in aqueous electrolyte solutions. It can be desirable to avoid introducing certain organic solvents and/or extraneous salts into aqueous electrolyte solutions. ... Incyte Corporation

07/05/18 / #20180191016

Flow batteries incorporating a phenothiazine compound within an aqueous electrolyte solution

Flow batteries can include a first half-cell containing a first aqueous electrolyte solution, a first electrolyte receptacle, a second half-cell containing a second aqueous electrolyte solution, a second electrolyte receptacle, and a separator disposed between the first half-cell and the second half-cell. The first aqueous electrolyte solution contains a first redox-active material and first mobile ions that are each continuously soluble, and the second aqueous electrolyte solution contains a second redox-active material and second mobile ions that are each continuously soluble. ... Incyte Corporation

07/05/18 / #20180191012

Aqueous pyridinium cation-based redox flow batteries

The present invention provides an aqueous redox flow battery comprising a negative electrode immersed in an aqueous liquid negative electrolyte, a positive electrode immersed in an aqueous liquid positive electrolyte, and a cation-permeable separator (e.g., a porous membrane, film, sheet, or panel) between the negative electrolyte from the positive electrolyte. During charging and discharging, the electrolytes are circulated over their respective electrodes. ... Incyte Corporation

07/05/18 / #20180191008

Mechanical energy storage in flow batteries to enhance energy storage

A hybrid flow redox battery system includes an electrochemical cell with an ion-exchange membrane, an anode, and a cathode, an anolyte tank, a catholyte tank, one or more tank separators, a plurality of electrolyte pathways, one or more turbines, and one or more power generation circuits. The anolyte tank includes a lower anolyte opening positioned below an upper anolyte opening. ... Incyte Corporation

07/05/18 / #20180191005

Redox flow battery system

Means for passing cooling air to the air circulation gaps or passages for cooling the electrolyte in or each inner tank.. . ... Incyte Corporation

07/05/18 / #20180191000

Titanium product

There is provided a titanium product for a separator of a polymer electrolyte fuel cell (pefc). The titanium product includes a substrate made of a titanium or a titanium alloy, and a passivation film formed on a surface of the substrate, wherein the passivation film includes a li-containing titanium oxide layer in its surface layer. ... Incyte Corporation

07/05/18 / #20180190999

Bipolar plate, cell frame, cell stack and redox-flow battery

A bipolar plate is a bipolar plate for a battery, the bipolar plate having a positive electrode disposed on a first surface side thereof and a negative electrode disposed on a second surface side thereof, wherein at least one of the first surface and the second surface is provided with a flow path through which an electrolyte flows. The flow path includes an introduction port for the electrolyte, a discharge port for the electrolyte, and a groove section which is located between the introduction port and the discharge port and guides the electrolyte to a predetermined route. ... Incyte Corporation

07/05/18 / #20180190997

Alkaline dry cell

An alkaline dry cell includes a positive electrode, a negative electrode, and an alkaline electrolyte solution. The negative electrode includes a terephthalic acid compound and a negative electrode active material containing zinc. ... Incyte Corporation

07/05/18 / #20180190995

Method for manufacturing cathode with improved mass transfer capability and cathode manufactured by the method

A method of manufacturing a cathode with improved mass transfer capability includes (a) mixing a metal-supported catalyst with an alkane compound having a thiol group and masking a surface of the metal-supported catalyst with the alkane compound having the thiol group by coating; (b) mixing the metal-supported catalyst masked with the alkane compound having the thiol group, with a polymer electrolyte and a solvent to produce a slurry and manufacturing the cathode using the slurry; and (c) producing a membrane electrode assembly (mea) using the cathode, an electrolyte membrane and an anode and applying a voltage to the membrane electrode assembly to remove the alkane compound having the thiol group.. . ... Incyte Corporation

07/05/18 / #20180190992

Electrochemical accumulator, with planar architecture obtained in part by printing

A metal-ion accumulator, including a metal element of flat surface forming a current collector of an electrode of one polarity; an insulating layer, deposited on the metal element while defining an interlocking pattern; a layer forming a current collector of an electrode of opposite polarity to the one having the current collector formed by the metal element, the collector layer being deposited on the interlocking pattern of the insulating layer; an electrode layer, deposited on the metal element according to a pattern at least partly interlocked in the interlocking pattern; an electrode layer of opposite polarity to the one deposited on the metal element, the layer of opposite polarity being deposited on the collector layer according to the interlocking pattern; a layer of electrolyte deposited at least in the spaces between the two layers of active materials of opposite polarity.. . ... Incyte Corporation

07/05/18 / #20180190983

Nickel composite hydroxide and manufacturing method thereof, cathode active material for nonaqueos-electrolyte secondary battery and manufacturing method thereof, and nonaqueous-electrolyte secondary battery

Provided are a cathode active material having a suitable particle size and high uniformity, and a nickel composite hydroxide as a precursor of the cathode active material. When obtaining nickel composite hydroxide by a crystallization reaction, nucleation is performed by controlling a nucleation aqueous solution that includes a metal compound, which includes nickel, and an ammonium ion donor so that the ph value at a standard solution temperature of 25° c. ... Incyte Corporation

07/05/18 / #20180190978

Transition metal-containing composite hydroxide and manufacturing method thereof, positive electrode active material for a non-aqueous electrolyte secondary battery and manufacturing method thereof, and non-aqueous electrolyte secondary battery

Provided is a positive electrode active material that is capable of simultaneously improving the battery capacity, output characteristics and cycling characteristics of a secondary battery. When obtaining a transition metal-containing composite hydroxide that is a precursor to the positive electrode active material, by adjusting the ph value of a reaction aqueous solution to be within the range 12.0 to 14.0 and performing generation of nuclei (nucleation), and then adjusting the ph value of the reaction aqueous solution to be within the range 10.5 to 12.0 and causing the nuclei to grow (particle growth), atmosphere control is performed at least one time in which the reaction atmosphere during nucleation and in the initial stage of particle growth is adjusted to be a non-oxidizing atmosphere, and during particle growth is switched to be an oxidizing atmosphere having an oxygen concentration that is 5% by volume or more by directly introducing an oxidizing gas into the reaction aqueous solution while continuing the supply of a raw material aqueous solution, and then is further switched to a non-oxidizing atmosphere by directly introducing an inert gas into the reaction aqueous solution while continuing the supply of the raw material aqueous solution.. ... Incyte Corporation

07/05/18 / #20180190973

Systems and methods of preparing lithium sulfur electrode using sacrificial template

Embodiments described herein relate generally to lithium sulfur batteries and methods of producing the same. As described herein, preventing coarsening of sulfur during the well-known melt-diffusion processing of cathodes allows a high areal capacity of 10.7 mah/cm2 at current density of 3.4 ma/cm2 (c-rate of 1/5 h−1). ... Incyte Corporation

07/05/18 / #20180190972

Negative electrode for power storage device and power storage device

A decomposition reaction of an electrolyte solution and the like caused as a side reaction of charge and discharge is minimized in repeated charge and discharge of a lithium ion battery or a lithium ion capacitor, and thus the lithium ion battery or the lithium ion capacitor can have long-term cycle performance. A negative electrode for a power storage device includes a negative electrode current collector and a negative electrode active material layer which includes a plurality of particles of a negative electrode active material. ... Incyte Corporation

07/05/18 / #20180190911

Functional hole transport materials for optoelectronic and/or electrochemical devices

The present invention relates to a compound of formula (i) based on a structure including functionalized spirofluorene and fused aromatics or non-aromatic rings with at least one heteroatom, and used as hole transporting material in a optoelectronic and/or photoelectrochemical device.. . ... Incyte Corporation

07/05/18 / #20180190478

Inorganic and organic mass spectrometry systems and methods of using them

Certain configurations of systems and methods that can detect inorganic ions and organic ions in a sample are described. In some configurations, the system may comprise one, two, three or more mass spectrometer cores. ... Incyte Corporation

07/05/18 / #20180190439

Flexible and shape-conformal rope-shape supercapacitors

Provided is a rope-shaped supercapacitor having a first and second conductive porous electrode in a rod shape, where the pores are filled with an electrolyte and an electrode active material. The pores of the first electrode may contain activated carbon or isolated graphene sheets. ... Incyte Corporation

07/05/18 / #20180190438

Dye sensitized solar cell module and dye sensitized solar cell comprising the same

The present invention relates to a dye-sensitized solar cell module, and more particularly, to a dye-sensitized solar cell module capable of minimizing a burst phenomenon of the dye-sensitized solar cell module caused by the bubbles by preventing occurrence of bubbles in an electrolyte solution, and securing reliability by preventing separation of a dye adsorbed onto a oxide semiconductor, and a dye-sensitized solar cell including the same.. . ... Incyte Corporation

07/05/18 / #20180190099

System and method of biomechanical posture detection and feedback

A system and method are described herein for a sensor device which biomechanically detects in real-time a user's movement state and posture and then provides real-time feedback to the user based on the user's real-time posture. The feedback is provided through immediate sensory feedback through the sensor device (e.g., a sound or vibration) as well as through an avatar within an associated application with which the sensor device communicates.. ... Incyte Corporation

07/05/18 / #20180189720

Event detection system and method for real-time inventory management system

A method and system of detecting events and updating inventory data in an inventory management system. The system is configured to sense and monitor inventory levels at one or more inventory locations, each having a load sensor that is configured to sense the weight of inventory items at the inventory location and generate a representative sensor signal. ... Incyte Corporation

07/05/18 / #20180188770

Memory clock frequency adjusting method, mainboard, and computer operating system

A memory clock frequency adjusting method suitable for a computer device is provided. The computer device includes a basic input output system (bios) and a memory. ... Incyte Corporation

07/05/18 / #20180188769

Memory overclocking method and computer device

A memory overclocking method adapted for a computer device is provided. The computer device includes a basic input output system and a memory. ... Incyte Corporation

07/05/18 / #20180188588

Display device

A display device comprises a casing, at least one adhesive member, a display panel and a flexible frame. The casing comprises a bottom plate and a plurality of lateral plates, and the plurality of lateral plates respectively connected to sides of the bottom plate so as to form an accommodating space within. ... Incyte Corporation

07/05/18 / #20180188281

Flow cell liquid degassing system and method

A system utilizes a flow cell for holding an analyte of interest for examination, such as a genetic material to be imaged for sequencing. Liquids, such as reagents and washing fluids are introduced into the flow cell during operations. ... Incyte Corporation

07/05/18 / #20180188272

Composition, device and imaging system for analysis using chemiluminescent probes

The present invention provides a method for the rapid monitoring of biological analytes in a point-of-care setting by providing a smart phone; providing a sample chamber; providing a sample; providing a dark box with a smartphone holder attached to the dark box top with the camera opening positioned about the aperture, adding a biological specimen suspected of containing a biological analyte in the sample chamber; adding a bis(2,4,6-trichlorophenyl) oxalate, an imidazole and a fluorophore to the sample chamber to react with the biological analyte; placing the sample chamber into the dark box; generating an emission from the fluorophore in response to the reaction with the biological analyte; and recording a set of time-lapse images of the emission with the smartphone.. . ... Incyte Corporation

07/05/18 / #20180188268

Cardiomyocyte-specific biological markers and uses thereof

The present invention is directed to particular monoclonal antibodies and fragments thereof that find use in the detection and isolation of in vitro differentiated cardiomyocytes. In particular, the present invention relates to lsmem2 biomarkers, including monoclonal antibodies having specificity for cell surface protein lsmem2 and to methods of using such biomarkers for diagnosis of cardiovascular injury.. ... Incyte Corporation

07/05/18 / #20180188249

Improved bacterial endotoxin test for the determination of endotoxins

Herein is reported a method for determining bacterial endotoxin at low concentrations in a sample of an antibody (that has been produced using bacterial cells) comprising the following steps in the following order: i) adding magnesium ions to the sample, ii) diluting the sample, iii) dialyzing the sample having a ph-value of 5.7-8.0 against an endotoxin-free aqueous solution, and iv) determining bacterial endotoxin in the sample using a bacterial endotoxin test, particularly the limulus amoebocyte lysate as say.. . ... Incyte Corporation

07/05/18 / #20180188247

Flushable test strip

We disclose a novel diagnostic test strip which may be used to conduct biochemical assays for analytes in liquid samples. The disclosed test strip may be loaded with much smaller volumes of sample than traditional test strips. ... Incyte Corporation

07/05/18 / #20180188244

Protein detection method

Described herein are systems and methods for detecting a target analyte in a sample with electrodes, comprising a linker and an antibody attached to the linker, and measuring an electrocatalytic signal changes generated by binding of an analyte in the sample to the antibody. Also disclosed herein are kits for electrochemical detection of protein analytes.. ... Incyte Corporation

07/05/18 / #20180188240

Portable device for detection of harmful substances

A self-contained apparatus and methods for detecting the presence of any specified substance in any medium. A sample of the medium is placed in a capsule, along with a solvent and a sensor configured to test for a target analyte. ... Incyte Corporation

07/05/18 / #20180188230

Devices and methods for sample analysis

Methods, devices, and systems for analyte analysis using a nanopore are disclosed. The methods, devices, and systems utilize a first and a second binding member that each specifically bind to an analyte in a biological sample. ... Incyte Corporation

07/05/18 / #20180188202

Nox sensor with catalytic filter and polarisation

A nox gas sensor for placing in a gas stream of a heat engine exhaust device. The sensor includes a sensing element having a solid electrolyte with a first surface on which there extend a work electrode, a reference electrode, and a counter-electrode. ... Incyte Corporation

07/05/18 / #20180188200

Accurate analyte measurements for electrochemical test strip based on sensed physical characteristic(s) of the sample containing the analyte and derived biosensor parameters

Various embodiments for a method that allow for a more accurate analyte concentration with a biosensor by determining at least one physical characteristic of the sample containing the analyte and deriving a parameter relating to the biosensor to attain accurate glucose concentration.. . ... Incyte Corporation

07/05/18 / #20180188199

Improved biosensor system analyte measurement

Methods and biosensor systems for compensating an analyte measurement are provided. The methods and systems determine a secondary output signal based on the measured primary output signal in order to better approximate the effects of an extraneous stimulus on the primary output signal under actual measurement conditions. ... Incyte Corporation

07/05/18 / #20180188142

Sample prep method

Disclosed is a method of supported liquid extraction (sle), wherein adsorption of at least one analyte to a solid phase is performed in the presence of salt. The method may include contacting a sample with salt, adsorption phase such as diatomaceous earth and optionally a subsequent step of phospholipid depletion. ... Incyte Corporation

07/05/18 / #20180188141

Reagent nozzle sipper mixing system and method

An analysis instrument may perform analytical operations on an analyte that is combined with multiple reagents prior to being introduced into a flow cell. The instrument may include a nozzle sipper that aspirates reagents from a recipient, along with an analyte. ... Incyte Corporation

07/05/18 / #20180187326

Sensor growth controller

A method for plating electrodes includes contacting a substrate with an electrolyte, the substrate comprising a plurality of working electrodes, applying an electric potential to one or more working electrodes of the plurality of working electrodes, monitoring a separate current through each of the one or more working electrodes of the plurality of working electrodes, and in response to determining that a first current through a first electrode of the plurality of working electrodes has reached a predetermined value, interrupting the first current through the first working electrode.. . ... Incyte Corporation

07/05/18 / #20180187319

Electrochemical hydrogen pump

An electrochemical hydrogen pump includes an electrolyte membrane having a pair of primary surfaces; a cathode catalyst layer provided on one primary surface of the electrolyte membrane; an anode catalyst layer provided on the other primary surface of the electrolyte membrane; a cathode gas diffusion layer provided on the cathode catalyst layer; an anode gas diffusion layer provided on the anode catalyst layer; and a voltage application device applying a voltage between the cathode catalyst layer and the anode catalyst layer, the anode gas diffusion layer includes a laminate of metal sheets which are provided with vents, and among the metal sheets, the maximum diameter of vents provided in a first metal sheet adjacent to the anode catalyst layer is smaller than the maximum diameter of vents provided in a second metal sheet adjacent to the first metal sheet.. . ... Incyte Corporation

07/05/18 / #20180187317

Method and apparatus for recovering metals and sulfur from feed streams containing metal sulfides and polysulfides

A system to remove sodium and sulfur from a feed stream containing alkali metal sulfides and polysulfides in addition to heavy metals. The system includes an electrolytic cell having an anolyte compartment housing an anode in contact with an anolyte. ... Incyte Corporation

07/05/18 / #20180187314

Cathodic protection of metal substrates

A metallic object to be protected from corrosion, such as a steel automobile body panel, is connected to an electron source as a cathode. An electrically isolating coating is disposed on the metallic object. ... Incyte Corporation

07/05/18 / #20180187255

Common line selector valve for a system

A system may include a flow cell to support analytes of interest; a selector valve coupled to the flow cell to select a flow path through the flow cell from a plurality of flow paths; a pump coupled to the flow cell to displace fluids through the selected flow path during an analysis operation; and control circuitry coupled to the selector valve to command the selector valve to select the selected flow path.. . ... Incyte Corporation

07/05/18 / #20180187249

Electrically active combinatorial chemical (eacc) chip for biochemical analyte detection

Apparatus and methods are disclosed for electrically active combinatorial-chemical (eacc) chips for biochemical analyte detection. An apparatus includes a substrate that has an array of regions defining multiple cells, wherein each of the cells includes a reaction cavity that contains multiple functional binding groups. ... Incyte Corporation

07/05/18 / #20180187162

Vascularized tissue, skin or mucosa equivalent

The disclosure relates to a method for the differentiation of stem cells to endothelial cells, vascular smooth muscle cells, fibroblasts and keratinocytes; their use in the production of a organotypic vascularized skin or mucosa model or composition; a method relating thereto; the use of the model or composition in the testing of pharmaceutical and/or cosmetic agents; and including therapeutic and cosmetic skin compositions developed or tested thereby.. . ... Incyte Corporation

07/05/18 / #20180187160

In vitro production of cholangiocytes

This invention relates to the efficient generation of cholangiocyte progenitor (cp) cells. Foregut stem cells (fscs) are cultured in a hepatic induction medium comprising bone morphogenetic protein (bmp) and a tgfβ signalling inhibitor to produce a population of hepatoblasts. ... Incyte Corporation

07/05/18 / #20180187151

Methods for obtaining regulatory t cells and uses thereof

Disclosed is a method for obtaining a population of human treg cells including the steps of: (a) culturing a population of human monocytes with a medium including an amount of an interleukin-34 (il-34) polypeptide in order to obtain a population of immunosuppressive macrophages; (b) co-culturing a population of human peripheral blood mononuclear cells (pbmcs) and the population of immunosuppressive macrophages obtained at step (a).. . ... Incyte Corporation

07/05/18 / #20180187150

Method for the cryopreservation of tumour-infiltrating lymphocytes

The invention relates to a method for the cryopreservation of at least one sample of tumour-infiltrating lymphocytes, comprising the following steps: i) the in vitro culture of tumour-infiltrating lymphocytes using a collection of samples of in-transit skin nodules, ganglion or metastasis, from a patient with a stage iii or iv melanoma, said step comprising the emergence of the tumour-infiltrating lymphocytes contained in the sample of in-transit skin nodules, ganglion or metastasis, followed by the stimulation of the tumour-infiltrating lymphocytes resulting from the emergence step, and, subsequently, the amplification of the stimulated tumour infiltrating lymphocytes; ii) the mixing of at least one sample obtained in step (i) with a composition comprising, in a physiologically acceptable medium, a) human albumin serum, b) at least one saccharide, and c) at least two ingredients selected from among dmso, l-cysteine, coenzyme q10 and c3-c5 alkanediols; and subsequently iii) the freezing of the mixture obtained in step (ii).. . ... Incyte Corporation

07/05/18 / #20180187148

Target populations of oligodendrocyte precursor cells and methods of making and using same

This application provides for enriched target populations oligodendrocyte precursor cells (opcs) that can differentiate into oligodendrocytes. The target opcs may be expanded and optionally subjected to conditions to induce their differentiation into oligodendrocytes. ... Incyte Corporation

07/05/18 / #20180186939

Method for the production of hydrogel comprising chitosan and negatively charged polyelectrolytes, and cellular, porous material resulting from said hydrogel

The third (iii) and fourth (iv) steps are replaced by a mixing fifth step (v), comprising mixing an acidified aqueous medium including at least one compound (c) comprising at least one unit of a hexose or a unit derived from a hexose, and/or at least one phosphate of said compound (c), with said mixture comprising at least the powders (a) and (b) obtained from the second step (ii).. . ... Incyte Corporation

07/05/18 / #20180186932

Electrochromic composition and electrochromic element

An electrochromic composition is provided. The electrochromic composition includes 0.5˜10 parts by weight of a first oxidizable polymer, 0.5˜10 parts by weight of a reducible organic compound, 0.5˜20 parts by weight of an electrolyte, and 60˜98.5 parts by weight of a solvent. ... Incyte Corporation

07/05/18 / #20180186897

Novel vaccines in prevention and treatment of malaria

The present invention provides a pharmaceutical composition, for example a vaccine, which comprises a rifin, which is able to bind to a mutated lair-1 fragment, which broadly binds to erythrocytes infected with plasmodium falciparum. Such a rifin may be useful in the prevention and/or treatment of malaria.. ... Incyte Corporation

07/05/18 / #20180186738

Crystalline l-arginine salt of (r)-2-(7-(4-cyclopentyl-3- (trifluoromethyl)benzyloxy)-1,2,3, 4-tetrahydrocyclo-penta [b]indol-3-yl)acetic acid(compound1) for use in sipi receptor-associated disorders

The present invention relates to, inter alia, a novel crystalline free-plate habit or morphology, processes for preparing the crystalline free-plate habit, and uses of the crystalline free-plate habit of the l-arginine salt of (r)-2-(7-(4-cyclopentyl-3-(trifluoromethyl)benzyloxy)-1,2,3,4-tetrahydrocyclo-penta[b]indol-3-yl)acetic acid (compound 1) in the treatment of s1p1 receptor-associated disorders, for example, diseases and disorders mediated by lymphocytes, transplant rejection, autoimmune diseases and disorders, inflammatory diseases and disorders (e.g., acute and chronic inflammatory conditions), cancer, and conditions characterized by an underlying defect in the vascular integrity or that are associated with angiogenesis such as may be pathologic (e.g., as may occur in inflammation, tumor development, and atherosclerosis).. . ... Incyte Corporation

07/05/18 / #20180186704

Substrate/oriented apatite-type composite oxide film complex and method for producing same

Provided is a substrate/oriented apatite-type composite oxide film complex which is suitable as a solid electrolyte for a battery, a sensor, a separation membrane, or the like, and can be produced inexpensively. Proposed is a substrate/oriented apatite-type composite oxide film complex provided with an oriented apatite-type composite oxide film on a substrate, wherein a film thickness of the oriented apatite-type composite oxide film is 10.0 μm or less, a degree of orientation (lotgering method) thereof is 0.6 or more, and a material of the substrate at a side on which at least the oriented apatite-type composite oxide film is formed is a metal, an alloy, a ceramic, or a composite material thereof.. ... Incyte Corporation

07/05/18 / #20180186666

System and method for reducing the dissolved solids of a non-potable aqueous flow

The present disclosure describes a flow-electrode capacitive deionization (fcdi) desalination system and method of use. The system employs clusters of tubular membranes oriented parallel to each other, each membrane having an internal flow path capable of receiving an electrolyte slurry (carbon slurry) therethrough. ... Incyte Corporation








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